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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-Chloro-6-fluorophenol Manufacturer/High quality/Best price/In stock

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Chloro-6-Fluorophenol supplier in China

Cas:2040-90-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-chloro-6-fluoro-phenol

Cas:2040-90-6

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥98% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

2-Chloro-6-fluorophenol CAS:2040-90-6

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $245.0 / 255.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 2040-90-6 with competitive price

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Chloro-6-fluorophenol 2040-90-6

Cas:2040-90-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2040-90-6

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 2040-90-6 ,2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Chloro-6-Fluorophenol

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

2-chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

2-Chloro-6-fluorophenol 2040-90-6

Cas:2040-90-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2040-90-6--2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Chloro-6-fluorophenol Basic information Product Name: 2-Chloro-6-fluorophenol Synonyms: 2-CHLORO-6-FLUOROPHENOL;Chlorofluorophenol3;2-Chloro-6-fluorophenol, 97+%;6-CHLORO-2-FLUORO PHENOL;2-Chloro-6-flurophenol;2-Chloro-6-fluorophenol, 98%,

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2040-90-6 CAS NO.2040-90-6

Cas:2040-90-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-Chloro-6-fluorophenol cas no. 2040-90-6 98%

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-Chloro-6-fluorophenol

Cas:2040-90-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

2-chloro-6-fluorophenyl isopropylcarbamate
899427-23-7

2-chloro-6-fluorophenyl isopropylcarbamate

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; ethanol at 20℃; for 2h;98%
(2-chloro-6-fluorophenyl)(isopropoxy)dimethylsilane
1228447-85-5

(2-chloro-6-fluorophenyl)(isopropoxy)dimethylsilane

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol; water at 20℃; for 16h; Inert atmosphere;94%
2-fluorophenol
367-12-4

2-fluorophenol

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With 1,3-dichloro-5,5-dimethylhydantoin; diisopropylamine hydrochloride In toluene at 0℃; for 4h; Darkness; regioselective reaction;91%
With tetrachloromethane; chlorine
With chlorine In tetrachloromethane
Multi-step reaction with 5 steps
1.1: TMEDA / diethyl ether; pentane / 0.5 h / 20 °C
2.1: n-butyllithium; TMEDA / diethyl ether; pentane / 1 h / -78 °C
2.2: C2Cl6 / diethyl ether; pentane / 1 h / -78 °C
3.1: 0.210 g / aq. HCl / methanol / -78 - 20 °C
4.1: 98 percent / aq. NaOH / ethanol; tetrahydrofuran / 2 h / 20 °C
View Scheme
With diisobutylamine; sulfuryl dichloride In toluene at 20℃;
2-(2-fluoro-6-chlorophenyl)oxypyridine

2-(2-fluoro-6-chlorophenyl)oxypyridine

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Stage #1: 2-(2-fluoro-6-chlorophenyl)oxypyridine With methyl trifluoromethanesulfonate In toluene at 100℃; for 2h; Inert atmosphere;
Stage #2: With sodium ethanolate for 1h; Reflux; Inert atmosphere;
78%
2-monochlorophenol
95-57-8

2-monochlorophenol

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With acetic acid; Selectfluor; eosin y In water at 20℃; for 6h; Irradiation; Green chemistry;77%
Multi-step reaction with 3 steps
1.1: copper(l) iodide; 2-Picolinic acid; potassium phosphate / dimethyl sulfoxide / 24 h / 80 °C / Inert atmosphere
2.1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethyl acetate / 5 h / 80 °C
3.1: methyl trifluoromethanesulfonate / toluene / 2 h / 100 °C / Inert atmosphere
3.2: 1 h / Reflux; Inert atmosphere
View Scheme
1-chloro-3-fluoro-2-methoxybenzene
53145-38-3

1-chloro-3-fluoro-2-methoxybenzene

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With pyridine hydrochloride
With boron tribromide In dichloromethane at -78 - 20℃; for 16h;
2-fluorophenyl isopropylcarbamate
199585-08-5

2-fluorophenyl isopropylcarbamate

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: TMEDA / diethyl ether; pentane / 0.5 h / 20 °C
2.1: n-butyllithium; TMEDA / diethyl ether; pentane / 1 h / -78 °C
2.2: C2Cl6 / diethyl ether; pentane / 1 h / -78 °C
3.1: 0.210 g / aq. HCl / methanol / -78 - 20 °C
4.1: 98 percent / aq. NaOH / ethanol; tetrahydrofuran / 2 h / 20 °C
View Scheme
C13H20FNO2Si

C13H20FNO2Si

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium; TMEDA / diethyl ether; pentane / 1 h / -78 °C
1.2: C2Cl6 / diethyl ether; pentane / 1 h / -78 °C
2.1: 0.210 g / aq. HCl / methanol / -78 - 20 °C
3.1: 98 percent / aq. NaOH / ethanol; tetrahydrofuran / 2 h / 20 °C
View Scheme
C13H19ClFNO2Si

C13H19ClFNO2Si

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 0.210 g / aq. HCl / methanol / -78 - 20 °C
2: 98 percent / aq. NaOH / ethanol; tetrahydrofuran / 2 h / 20 °C
View Scheme
2,2,6-trichloro-6-fluoro-1,1-cyclohexane-diol
145706-45-2

2,2,6-trichloro-6-fluoro-1,1-cyclohexane-diol

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Å molecular sieve In pyridine
C12H19ClFNSi

C12H19ClFNSi

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol; water at 20℃; for 16h; Inert atmosphere;277 mg
2-(2-chlorophenoxy)pyridine
4783-70-4

2-(2-chlorophenoxy)pyridine

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide / ethyl acetate / 5 h / 80 °C
2.1: methyl trifluoromethanesulfonate / toluene / 2 h / 100 °C / Inert atmosphere
2.2: 1 h / Reflux; Inert atmosphere
View Scheme
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

2-chloro-6-fluorophenyl trifluoromethanesulfonate
1443684-70-5

2-chloro-6-fluorophenyl trifluoromethanesulfonate

Conditions
ConditionsYield
With pyridine at 0 - 20℃;100%
With pyridine In dichloromethane at 0 - 20℃; for 3h;
With pyridine In dichloromethane at 0℃; for 3h;1.25 g
With pyridine In dichloromethane at 0℃; for 3h;
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

4-chlorobenzoyl chloride
586-75-4

4-chlorobenzoyl chloride

C13H7BrClFO2
1443037-89-5

C13H7BrClFO2

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;97%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

4-methyl-benzoyl chloride
874-60-2

4-methyl-benzoyl chloride

2-chloro-6-fluorophenyl 4-methylbenzoate
1443037-91-9

2-chloro-6-fluorophenyl 4-methylbenzoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;96%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;96%
With triethylamine In dichloromethane at 0℃; for 5h;96%
With sodium hydroxide at 0℃; for 3h;
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

4-chloro-benzoyl chloride
122-01-0

4-chloro-benzoyl chloride

4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester
1443037-88-4

4-chloro-benzoic acid 2-chloro-6-fluoro-phenyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;95%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;95%
With triethylamine In dichloromethane at 0℃; for 5h;95%
With sodium hydroxide In water at 0 - 5℃;85%
With sodium hydroxide at 0 - 5℃;82%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

methyl iodide
74-88-4

methyl iodide

1-chloro-3-fluoro-2-methoxybenzene
53145-38-3

1-chloro-3-fluoro-2-methoxybenzene

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 3h;94%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

4-fluorobenzoyl chloride
403-43-0

4-fluorobenzoyl chloride

2-chloro-6-fluorophenyl 4-fluorobenzoate
1443037-87-3

2-chloro-6-fluorophenyl 4-fluorobenzoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;94%
With triethylamine In dichloromethane at 0℃; for 5h;94%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;92%
With sodium hydroxide at 0℃; for 3h;
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

4-iodobenzoic acid chloride
1711-02-0

4-iodobenzoic acid chloride

2-chloro-6-fluorophenyl 4-iodobenzoate
1443037-90-8

2-chloro-6-fluorophenyl 4-iodobenzoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;93%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;93%
With sodium hydroxide at 0℃; for 3h;
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

benzyl bromide
100-39-0

benzyl bromide

2-chloro-6-fluorophenyl phenylmethyl ether
938180-34-8

2-chloro-6-fluorophenyl phenylmethyl ether

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide for 12h;92%
With potassium carbonate In acetone at 65℃; for 16h;
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(2-chloro-6-fluorophenoxy)(tert-butyl)dimethylsilane
1434722-77-6

(2-chloro-6-fluorophenoxy)(tert-butyl)dimethylsilane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 25℃;90%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(S)-2-(6-(hydroxymethyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethan-1-ol

(S)-2-(6-(hydroxymethyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethan-1-ol

(S)-2-(6-((2-chloro-6-fluorophenoxy)methyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethan-1-ol

(S)-2-(6-((2-chloro-6-fluorophenoxy)methyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethan-1-ol

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 20℃; for 1h;89%
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 20℃; for 1h;89%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

sodium 2-chloro-6-fluorophenolate

sodium 2-chloro-6-fluorophenolate

Conditions
ConditionsYield
With sodium hydroxide In methanol Inert atmosphere; Schlenk technique;87%
3-bromo-2-chloropyridine
52200-48-3

3-bromo-2-chloropyridine

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

3-bromo-2-(2-chloro-6-fluorophenoxy)pyridine
1167991-82-3

3-bromo-2-(2-chloro-6-fluorophenoxy)pyridine

Conditions
ConditionsYield
With caesium carbonate In dimethyl sulfoxide at 140℃;80%
With caesium carbonate In dimethyl sulfoxide at 120℃;
2-iodo-propane
75-30-9

2-iodo-propane

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

1-chloro-3-fluoro-2-isopropoxybenzene

1-chloro-3-fluoro-2-isopropoxybenzene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 12h;78%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

N-(3-(bromomethyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

N-(3-(bromomethyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

N-(3-((2-chloro-6-fluorophenoxy)methyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

N-(3-((2-chloro-6-fluorophenoxy)methyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 4h;74%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(S)-(2-methyl-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)methanol

(S)-(2-methyl-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)methanol

(S)-6-((2-chloro-6-fluorophenoxy)methyl)-2-methyl-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

(S)-6-((2-chloro-6-fluorophenoxy)methyl)-2-methyl-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 20℃; for 1h;73%
With di-isopropyl azodicarboxylate; triphenylphosphine at 20℃; for 1h;73%
Ethyl 2-butynoate
4341-76-8

Ethyl 2-butynoate

2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(E)-3-(2-chloro-6-fluoro-phenoxy)-but-2-enoic acid ethyl ester
1191997-67-7

(E)-3-(2-chloro-6-fluoro-phenoxy)-but-2-enoic acid ethyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Reflux;71%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(1-((3-(trifluoromethyl)phenyl)sulfonyl)-1H-indol-6-yl)methanol

(1-((3-(trifluoromethyl)phenyl)sulfonyl)-1H-indol-6-yl)methanol

6-((2-chloro-6-fluorophenoxy)methyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)-1H-indole

6-((2-chloro-6-fluorophenoxy)methyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)-1H-indole

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 20℃; Mitsunobu Displacement;69%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline-6-carboxylic acid

1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline-6-carboxylic acid

2-chloro-6-fluorophenyl 1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline-6-carboxylate

2-chloro-6-fluorophenyl 1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline-6-carboxylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In 1,2-dichloro-ethane at 60℃;67%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In 1,2-dichloro-ethane at 60℃;18 mg
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

2-bromoethanol
540-51-2

2-bromoethanol

2-(2-chloro-6-fluorophenoxy)ethanol

2-(2-chloro-6-fluorophenoxy)ethanol

Conditions
ConditionsYield
With sodium hydroxide at 90℃; for 16h;64.5%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

ethyl iodide
75-03-6

ethyl iodide

1-chloro-2-ethoxy-3-fluorobenzene

1-chloro-2-ethoxy-3-fluorobenzene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 16h;63%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

N-ethyl-N-(3-(1-hydroxyethyl)phenyl)-3-(trifluoromethyl)benzenesulfonamide

N-ethyl-N-(3-(1-hydroxyethyl)phenyl)-3-(trifluoromethyl)benzenesulfonamide

N-(3-(1-(2-chloro-6-fluorophenoxy)ethyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

N-(3-(1-(2-chloro-6-fluorophenoxy)ethyl)phenyl)-N-ethyl-3-(trifluoromethyl)benzenesulfonamide

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 2h;62%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

C6H3ClFNO3

C6H3ClFNO3

Conditions
ConditionsYield
With sulfuric acid; potassium nitrate at 0℃; for 0.25h;61%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(1-((3-(trifluoromethyl)phenyl)sulfonyl)indolin-6-yl)methanol

(1-((3-(trifluoromethyl)phenyl)sulfonyl)indolin-6-yl)methanol

6-((2-chloro-6-fluorophenoxy)methyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline

6-((2-chloro-6-fluorophenoxy)methyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)indoline

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 20℃; Mitsunobu Displacement;44%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

2-(tert-butoxycarbonylamino)ethyl methanesulfonate
96628-67-0

2-(tert-butoxycarbonylamino)ethyl methanesulfonate

tert-butyl (2-(2-chloro-6-fluorophenoxy)ethyl)carbamate

tert-butyl (2-(2-chloro-6-fluorophenoxy)ethyl)carbamate

Conditions
ConditionsYield
Stage #1: 2-chloro-6-fluorophenol With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: 2-(tert-butoxycarbonylamino)ethyl methanesulfonate In N,N-dimethyl-formamide at 100℃; for 16h;
42%
2-chloro-6-fluorophenol
2040-90-6

2-chloro-6-fluorophenol

(S)-isopropyl 2-(5-(2-bromoethoxy)-4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-[2,3'-bipyridin]-5'-yl)-2-(tert-butoxy)acetate

(S)-isopropyl 2-(5-(2-bromoethoxy)-4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-[2,3'-bipyridin]-5'-yl)-2-(tert-butoxy)acetate

(S)-isopropyl 2-(tert-butoxy)-2-(5-(2-(2-chloro-6-fluorophenoxy)ethoxy)-4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-[2,3'-bipyridin]-5'-yl)acetate

(S)-isopropyl 2-(tert-butoxy)-2-(5-(2-(2-chloro-6-fluorophenoxy)ethoxy)-4'-(4,4-dimethylpiperidin-1-yl)-6'-methyl-[2,3'-bipyridin]-5'-yl)acetate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 12h;41.5%

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