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AstaTech ( Chengdu) BioPharmaceutical Corp.

High quality, ISO9001 system. Application:Oseltamivir N-5

Oseltamivir N-5

Cas:204254-96-6

Min.Order:0 Metric Ton

FOB Price: $650.0 / 700.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

LIDE PHARMACEUTICALS LIMITED

/ LIDE PHARMA- Factory supply / Best price Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

Oseltamivir Intermediate manufacturer/supplier

Cas:204254-96-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:cool dry place Package:1kg/foil bag;25kg/drum Application:pharmaceutical intermediate Transpo

Hangzhou Think Chemical Co. Ltd

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate CAS No.:204254-96-6 Name: (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate Synonyms: [1S-(1a,5b,6

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethyl (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationships with ma

TIANFU 204254-96-6 (1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate CAS 204254-96-6

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 204254-96-6 with best quality

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate CAS204254-96-6

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name: Oseltamivir epoxide CAS: 204254-96-6 Molecular formula: C14H22O4 Molecular weight: 254.32 Appearance:White/off?white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Syntheses Materi

Oseltamivir epoxide

Cas:204254-96-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate 204254-96-6

Cas:204254-96-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate 99%

Cas:204254-96-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Qingdao Beluga Import and Export Co., LTD

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate CAS:204254-96-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of che

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate CAS:204254-96-6

Cas:204254-96-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available; 4) Reasonable & Compet

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-Ethylpropoxy)-Cyclohex-1-Ene-1-Carboxylate

Cas:204254-96-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Oseltamivir Intermediate 2

Cas:204254-96-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ethyl(3R,4S,5S)4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate

Cas:204254-96-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl(3R,4S,5S)4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate

Cas:204254-96-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Tianjin Kind Pharma Co., Ltd.

An intermediate of Oseltamivir. Factory direct sales, accept customization. Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive a

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

(1S,5R,6S)-Ethyl 5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

Cas:204254-96-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

ethyl (3R,4R,5R)-3-(1-ethyl-propoxy)-4-hydroxy-5-methanesulfonyloxycyclohex-1-ene-1-carboxylate
204254-92-2

ethyl (3R,4R,5R)-3-(1-ethyl-propoxy)-4-hydroxy-5-methanesulfonyloxycyclohex-1-ene-1-carboxylate

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol; water at 60℃; for 2h;
With potassium hydrogencarbonate In ethanol at 60℃; for 1h;2 g
With sodium hydrogencarbonate In ethanol at 60 - 65℃; for 1.5h; Inert atmosphere; Industrial scale; Large scale;1.55 kg
ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate
204254-90-0

ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate; dimethylsulfide borane complex; potassium hydrogencarbonate 1.) dichloromethane, -20 - -10 deg C, 0.2 h, 2.) ethanol, water, 55-65 deg C, 1 h; Yield given. Multistep reaction;
Stage #1: ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate With trimethylsilyl trifluoromethanesulfonate; dimethylsulfide borane complex In dichloromethane at -30 - -20℃; for 1h;
Stage #2: With sodium hydrogencarbonate In dichloromethane; water at 20℃; for 12h;
Stage #3: With potassium hydrogencarbonate In ethanol; water at 55 - 65℃; for 2h;
ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate
204254-84-2

ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / perchloric acid
2: 1.) BH3-SMe2, trimethylsilyl trifluoromethanesulfonate, 2.) potassium hydroden carbonate / 1.) dichloromethane, -20 - -10 deg C, 0.2 h, 2.) ethanol, water, 55-65 deg C, 1 h
View Scheme
Multi-step reaction with 2 steps
1.1: perchloric acid / 18 h
2.1: dimethylsulfide borane complex; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -30 - -20 °C
2.2: 12 h / 20 °C
2.3: 2 h / 55 - 65 °C
View Scheme
ethyl (3aR,5S,7R,7aR)-5-hydroxy-7-methanesulfonyloxy-2,2-dimethylhexahydrobenzo[1,3]dioxole-5-carboxylate
204254-81-9

ethyl (3aR,5S,7R,7aR)-5-hydroxy-7-methanesulfonyloxy-2,2-dimethylhexahydrobenzo[1,3]dioxole-5-carboxylate

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: pyridine; sulfuryl dichloride / dichloromethane / -30 - -20 °C
2.1: perchloric acid / 18 h
3.1: dimethylsulfide borane complex; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -30 - -20 °C
3.2: 12 h / 20 °C
3.3: 2 h / 55 - 65 °C
View Scheme
D-(-)-quinic acid
77-95-2

D-(-)-quinic acid

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: toluene-4-sulfonic acid / acetone / 2 h / Reflux; Large scale
2.1: ethanol / 2 h / 20 °C
2.2: 1 h / 0 - 10 °C
3.1: pyridine; sulfuryl dichloride / dichloromethane / -30 - -20 °C
4.1: perchloric acid / 18 h
5.1: dimethylsulfide borane complex; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -30 - -20 °C
5.2: 12 h / 20 °C
5.3: 2 h / 55 - 65 °C
View Scheme
2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: toluene-4-sulfonic acid / acetone / 2 h / Reflux; Large scale
2.1: ethanol / 2 h / 20 °C
2.2: 1 h / 0 - 10 °C
3.1: pyridine; sulfuryl dichloride / dichloromethane / -30 - -20 °C
4.1: perchloric acid / 18 h
5.1: dimethylsulfide borane complex; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -30 - -20 °C
5.2: 12 h / 20 °C
5.3: 2 h / 55 - 65 °C
View Scheme
(1S,3R,4S,5R)-3,4-O-isopropylidene-1,5-quinic lactone
32384-42-2

(1S,3R,4S,5R)-3,4-O-isopropylidene-1,5-quinic lactone

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: ethanol / 2 h / 20 °C
1.2: 1 h / 0 - 10 °C
2.1: pyridine; sulfuryl dichloride / dichloromethane / -30 - -20 °C
3.1: perchloric acid / 18 h
4.1: dimethylsulfide borane complex; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -30 - -20 °C
4.2: 12 h / 20 °C
4.3: 2 h / 55 - 65 °C
View Scheme
1-amino-2-propene
107-11-9

1-amino-2-propene

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4S,5R)-5-N-allyllamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate
312904-11-3

ethyl (3R,4S,5R)-5-N-allyllamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
With magnesium bromide In acetonitrile at 55℃; for 16h;97%
tert-butylamine
75-64-9

tert-butylamine

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

A

C14H20O3
1151665-78-9

C14H20O3

B

C14H23ClO4

C14H23ClO4

C

(3R,4S,5R)-[5-(tert-butylamino)-4-hydroxy-3-(pent-3-yloxy)]cyclohex-1-ene-1-carboxylic acid ethyl ester
651324-04-8

(3R,4S,5R)-[5-(tert-butylamino)-4-hydroxy-3-(pent-3-yloxy)]cyclohex-1-ene-1-carboxylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: tert-butylamine With magnesium chloride In toluene at 10℃; for 1h;
Stage #2: (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester In toluene at 60℃; for 48h; Temperature; Time;
A 1.65%
B 0.83%
C 95.8%
acetonitrile
75-05-8

acetonitrile

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(3R,4S,5R)-ethyl 5-acetylamino-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate
1443055-47-7

(3R,4S,5R)-ethyl 5-acetylamino-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate

Conditions
ConditionsYield
Stage #1: acetonitrile; (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester With boron trifluoride diethyl etherate at 0℃; for 1.16667h;
Stage #2: With water In acetonitrile at 0 - 20℃; for 4h;
Stage #3: With potassium carbonate In acetonitrile at 20℃; for 36h; diastereoselective reaction;
95%
tert-butylamine
75-64-9

tert-butylamine

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(3R,4S,5R)-[5-(tert-butylamino)-4-hydroxy-3-(pent-3-yloxy)]cyclohex-1-ene-1-carboxylic acid ethyl ester
651324-04-8

(3R,4S,5R)-[5-(tert-butylamino)-4-hydroxy-3-(pent-3-yloxy)]cyclohex-1-ene-1-carboxylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: tert-butylamine; (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester With magnesium chloride In toluene at 50℃; for 23h;
Stage #2: With citric acid
91%
Stage #1: tert-butylamine With magnesium chloride In toluene for 6h;
Stage #2: (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester In toluene at 25 - 50℃; for 20h;
89.7%
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl-(3R,4S,5R)-5-azido-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

ethyl-(3R,4S,5R)-5-azido-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

Conditions
ConditionsYield
Stage #1: (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester With water; ammonium chloride In ethanol for 0.333333h;
Stage #2: With sodium azide In ethanol at 68℃; for 14h;
90%
With sodium azide; ammonium chloride In ethanol; water at 65 - 75℃; for 8h;86.9%
With sodium azide; ammonium chloride In methanol; water at 65 - 70℃;70%
benzylamine
100-46-9

benzylamine

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4S,5R)-5-N-benzylamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate

ethyl (3R,4S,5R)-5-N-benzylamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Stage #1: benzylamine With zinc(II) chloride In tetrahydrofuran for 1h;
Stage #2: (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester In tetrahydrofuran at 50℃; for 24h; Reagent/catalyst; Temperature;
89%
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4S,5R)-5-amino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate
312904-12-4

ethyl (3R,4S,5R)-5-amino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 97 percent / MgBr2*OEt2 / acetonitrile; various solvent(s) / 16 h / 55 °C
2.1: ethanolamine; Pd/C / ethanol / 3 h / Heating
2.2: 77 percent / H2SO4
View Scheme
Multi-step reaction with 2 steps
1.1: zinc(II) chloride / tetrahydrofuran / 1 h
1.2: 24 h / 50 °C
2.1: hydrogen; palladium on activated charcoal / isopropyl alcohol; acetonitrile / 6 h / 60 °C / 760.05 Torr
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4R,5S)-5-N-allylamino-4-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
312904-15-7

ethyl (3R,4R,5S)-5-N-allylamino-4-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 97 percent / MgBr2*OEt2 / acetonitrile; various solvent(s) / 16 h / 55 °C
2.1: ethanolamine; Pd/C / ethanol / 3 h / Heating
2.2: 77 percent / H2SO4
3.1: various solvent(s)
4.1: Et3N / various solvent(s)
5.1: various solvent(s) / 15 h / 111 - 112 °C / 2625.21 - 3375.27 Torr
View Scheme
Multi-step reaction with 5 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: H2NCH2CH2OH / Pd/C / ethanol / 3 h / Heating
2.1: 6 h / 100 °C / 750.08 - 3750.38 Torr
3.1: Et3N / ethyl acetate / 0 - 20 °C
4.1: MeSO3H / ethanol / 2.67 h / Heating
5.1: ethyl acetate / 6 h / 112 °C / 750.08 - 4500.45 Torr
View Scheme
Multi-step reaction with 5 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: HOCH2CH2OH / Pd/C / ethanol / Heating
2.1: 6 h / 100 °C / 750.08 - 3750.38 Torr
3.1: Et3N / ethyl acetate / 0 - 20 °C
4.1: MeSO3H / ethanol / 2.67 h / Heating
5.1: ethyl acetate / 6 h / 112 °C / 750.08 - 4500.45 Torr
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4S,5R)-5-N-benzylideneamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate
332047-17-3

ethyl (3R,4S,5R)-5-N-benzylideneamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 97 percent / MgBr2*OEt2 / acetonitrile; various solvent(s) / 16 h / 55 °C
2.1: ethanolamine; Pd/C / ethanol / 3 h / Heating
2.2: 77 percent / H2SO4
3.1: various solvent(s)
View Scheme
Multi-step reaction with 2 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: H2NCH2CH2OH / Pd/C / ethanol / 3 h / Heating
2.1: 100 percent / toluene / 0.5 h / 110 °C
View Scheme
Multi-step reaction with 2 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: HOCH2CH2OH / Pd/C / ethanol / Heating
2.1: 100 percent / toluene / 0.5 h / 110 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4S,5R)-5-N-benzylideneamino-3-(1-ethylpropoxy)-4-methanesulfonyloxy-1-cyclohexene-1-carboxylate
332047-18-4

ethyl (3R,4S,5R)-5-N-benzylideneamino-3-(1-ethylpropoxy)-4-methanesulfonyloxy-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 97 percent / MgBr2*OEt2 / acetonitrile; various solvent(s) / 16 h / 55 °C
2.1: ethanolamine; Pd/C / ethanol / 3 h / Heating
2.2: 77 percent / H2SO4
3.1: various solvent(s)
4.1: Et3N / various solvent(s)
View Scheme
Multi-step reaction with 3 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: H2NCH2CH2OH / Pd/C / ethanol / 3 h / Heating
2.1: 100 percent / toluene / 0.5 h / 110 °C
3.1: 94 percent / Et3N / ethyl acetate / 1 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: HOCH2CH2OH / Pd/C / ethanol / Heating
2.1: 100 percent / toluene / 0.5 h / 110 °C
3.1: 94 percent / Et3N / ethyl acetate / 1 h / 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4R,5S)-4-N-acetylamino-5-N-allylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
312904-18-0

ethyl (3R,4R,5S)-4-N-acetylamino-5-N-allylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 97 percent / MgBr2*OEt2 / acetonitrile; various solvent(s) / 16 h / 55 °C
2.1: ethanolamine; Pd/C / ethanol / 3 h / Heating
2.2: 77 percent / H2SO4
3.1: various solvent(s)
4.1: Et3N / various solvent(s)
5.1: various solvent(s) / 15 h / 111 - 112 °C / 2625.21 - 3375.27 Torr
6.1: AcOH; MeSO3H / various solvent(s) / 15 h / 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: H2NCH2CH2OH / Pd/C / ethanol / 3 h / Heating
2.1: 6 h / 100 °C / 750.08 - 3750.38 Torr
3.1: Et3N / ethyl acetate / 0 - 20 °C
4.1: MeSO3H / ethanol / 2.67 h / Heating
5.1: ethyl acetate / 6 h / 112 °C / 750.08 - 4500.45 Torr
6.1: AcOH; MeSO3H / various solvent(s) / 0 - 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: MgBr2*OEt2 / acetonitrile; various solvent(s) / Heating
1.2: HOCH2CH2OH / Pd/C / ethanol / Heating
2.1: 6 h / 100 °C / 750.08 - 3750.38 Torr
3.1: Et3N / ethyl acetate / 0 - 20 °C
4.1: MeSO3H / ethanol / 2.67 h / Heating
5.1: ethyl acetate / 6 h / 112 °C / 750.08 - 4500.45 Torr
6.1: AcOH; MeSO3H / various solvent(s) / 0 - 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,5R,6R)-{7-(tert-butyl)-5-(pent-3-yloxy)-7-azabicyclo[4.1.0]}hept-3-ene-3-ethyl carboxylate

(1R,5R,6R)-{7-(tert-butyl)-5-(pent-3-yloxy)-7-azabicyclo[4.1.0]}hept-3-ene-3-ethyl carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: MgCl2 / toluene / 23 h / 50 °C
1.2: 91 percent / aq. citric acid
2.1: Et3N / toluene / 5 h / 70 °C
3.1: 93 percent / aq. K2CO3
View Scheme
Multi-step reaction with 2 steps
1.1: magnesium chloride / toluene / 6 h
1.2: 20 h / 25 - 50 °C
2.1: methanesulfonyl chloride / toluene / 1 h / 0 - 10 °C / Inert atmosphere
2.2: 3.5 h / 0 - 70 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(3R,4S,5R)-5-tert-Butylamino-3-(1-ethyl-propoxy)-4-methanesulfonyloxy-cyclohex-1-enecarboxylic acid ethyl ester

(3R,4S,5R)-5-tert-Butylamino-3-(1-ethyl-propoxy)-4-methanesulfonyloxy-cyclohex-1-enecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: MgCl2 / toluene / 23 h / 50 °C
1.2: 91 percent / aq. citric acid
2.1: Et3N / toluene / 5 h / 70 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4R,5S)-5-N,N-diallylamino-4-(1,1-dimethylethyl)amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
651324-06-0

ethyl (3R,4R,5S)-5-N,N-diallylamino-4-(1,1-dimethylethyl)amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: MgCl2 / toluene / 23 h / 50 °C
1.2: 91 percent / aq. citric acid
2.1: Et3N / toluene / 5 h / 70 °C
3.1: 93 percent / aq. K2CO3
4.1: 93 percent / PhSO3H / 5 h / 120 °C
View Scheme
Multi-step reaction with 3 steps
1.1: magnesium chloride / toluene / 6 h
1.2: 20 h / 25 - 50 °C
2.1: methanesulfonyl chloride / toluene / 1 h / 0 - 10 °C / Inert atmosphere
2.2: 3.5 h / 0 - 70 °C
3.1: benzenesulfonic acid / 5.5 h / 120 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

ethyl (3R,4R,5S)-4-N-acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
651324-07-1

ethyl (3R,4R,5S)-4-N-acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: MgCl2 / toluene / 23 h / 50 °C
1.2: 91 percent / aq. citric acid
2.1: Et3N / toluene / 5 h / 70 °C
3.1: 93 percent / aq. K2CO3
4.1: 93 percent / PhSO3H / 5 h / 120 °C
5.1: 95 percent / NaOAc / 4 h / 116 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-5-cyano-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester
382148-62-1

(3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-5-cyano-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-cyano-5-(1-ethyl-propoxy)-cyclohexanecarboxylic acid ethyl ester
382148-63-2

(1R,3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-cyano-5-(1-ethyl-propoxy)-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
3: 91 percent / H2 / Pd/C / ethyl acetate / 2585.81 Torr
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,3R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-thiocarbamoyl-cyclohexanecarboxylic acid ethyl ester
382148-59-6

(1R,3R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-thiocarbamoyl-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
3: 91 percent / H2 / Pd/C / ethyl acetate / 2585.81 Torr
4: 73 percent / (TMS)2S; NaOMe / N,N-dimethyl-acetamide / 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-thiocarbamoyl-cyclohexanecarboxylic acid ethyl ester
382148-64-3

(1R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-thiocarbamoyl-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
3: 91 percent / H2 / Pd/C / ethyl acetate / 2585.81 Torr
4: 7 percent / (TMS)2S; NaOMe / N,N-dimethyl-acetamide / 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-(4-phenyl-thiazol-2-yl)-cyclohexanecarboxylic acid ethyl ester

(1R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-(4-phenyl-thiazol-2-yl)-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
3: 91 percent / H2 / Pd/C / ethyl acetate / 2585.81 Torr
4: 73 percent / (TMS)2S; NaOMe / N,N-dimethyl-acetamide / 20 °C
5: 9 percent / dimethylformamide / 1 h / 20 °C
View Scheme
(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester
204254-96-6

(1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester

(1R,3R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-(4-phenyl-thiazol-2-yl)-cyclohexanecarboxylic acid ethyl ester

(1R,3R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(1-ethyl-propoxy)-5-(4-phenyl-thiazol-2-yl)-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 85 percent / toluene / 20 °C
2: 87 percent / imidasole / dimethylformamide / 20 °C
3: 91 percent / H2 / Pd/C / ethyl acetate / 2585.81 Torr
4: 73 percent / (TMS)2S; NaOMe / N,N-dimethyl-acetamide / 20 °C
5: 74 percent / dimethylformamide / 1 h / 20 °C
View Scheme

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