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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

Cas:2196-18-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

α,4'-Dihydroxy-3'-methoxypropiophenone CAS:2196-18-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializi

α,4'-Dihydroxy-3'-methoxypropiophenone CAS:2196-18-1

Cas:2196-18-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

Cas:2196-18-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

beta-Hydroxypropiovanillone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

β-Hydroxypropiovanillone

Cas:2196-18-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

α,4-Dihydroxy-3-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

α,4-Dihydroxy-3-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

α,4-Dihydroxy-3-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

β-Hydroxypropiovanillone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

α,4'-Dihydroxy-3'-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1 Application:C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

α,4'-Dihydroxy-3'-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri

α,4'-Dihydroxy-3'-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1Appearance:Powder Storage:1MT Package:Aluminium Foil Bag and Paper Drum Application:2196-18-1 Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airpo

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

2196-18-1

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Stable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

shanghai Tauto Biotech Co., Ltd

Appearance:powder or crystal Storage:-20degree Package:10mg,20mg,1g or on request Application:For research use only, like HPLC, Cell Culture, Animal Experiment, High Throughout Screening, etc.. Transportation:room temperature

3-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

β-Hydroxypropiovanillone manufacturer

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

α,4'-Dihydroxy-3'-methoxypropiophenone

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Shaanxi Cuicheng Biomedical Technology Co., Ltd. is located in Chuangzhi Industrial Park, Economic and Technological Development Zone, Hanzhong City, Shaanxi Province, China. It is a company specializing in natural medicines and high-throughput scree

β-hydroxypropiovanillone (2196-18-1)

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Jiashisheng Biotechnolgy Co.,Ltd

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

C10H12O4 α,4'-Dihydroxy-3'-methoxypropiophenone 2196-18-1

Cas:2196-18-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

3-chloro-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
7182-42-5

3-chloro-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
With sodium hydroxide In water at 20 - 65℃; for 1.5h; Reagent/catalyst; Temperature; Solvent; Industrial scale;100%
β-hydroxy-α-(2-methoxyphenoxy)4-hydroxy-3-methoxypropiophenone
22317-34-6

β-hydroxy-α-(2-methoxyphenoxy)4-hydroxy-3-methoxypropiophenone

A

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With formic acid; N-ethyl-N,N-diisopropylamine; Lumogen F Orange 240 In acetonitrile at 25℃; for 8h; Reagent/catalyst; UV-irradiation; Inert atmosphere;A 99%
B 96%
With formic acid; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 24h; Inert atmosphere; Irradiation;A 69%
B 74%
guaiacylglycerol-β-guaiacyl ether
7382-59-4

guaiacylglycerol-β-guaiacyl ether

A

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

C

1-(3-methoxy-4-hydroxyphenyl)ethanone
498-02-2

1-(3-methoxy-4-hydroxyphenyl)ethanone

Conditions
ConditionsYield
With oxygen; rose bengal In acetonitrile at 13℃; Irradiation;A 28 % Chromat.
B 15 % Chromat.
C 30 % Chromat.
3-acetoxy-1-<4-hydroxy-3-methoxy-phenyl>-propanone-(1)

3-acetoxy-1-<4-hydroxy-3-methoxy-phenyl>-propanone-(1)

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
With water; barium carbonate
3-bromo-1-<4-hydroxy-3-methoxy-phenyl>-propanone-(1)

3-bromo-1-<4-hydroxy-3-methoxy-phenyl>-propanone-(1)

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
With sodium hydroxide
4-benzyloxy-3-methoxyacetophenone
1835-11-6

4-benzyloxy-3-methoxyacetophenone

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 69 percent / Br2 / CHCl3; CCl4 / 1) 5 deg C, 20 min, 2) 5 deg C -> 40 deg C, 2 h
2: 95 percent / K2CO3 / dimethylformamide / 2 h / 25 °C
3: 1) K2CO3, 2) 1 M NaOH / 1) DMSO, 25 deg C, 10 min, 2) DMSO, H2O, 25 deg C, 1 h
4: 78 percent / NaBH4 / ethanol / 3 h / 5 - 25 °C
5: 28 percent Chromat. / O2, Rose Bengal / acetonitrile / 13 °C / Irradiation
View Scheme
β-hydroxy-α-(2-methoxyphenoxy)4-hydroxy-3-methoxypropiophenone
22317-34-6

β-hydroxy-α-(2-methoxyphenoxy)4-hydroxy-3-methoxypropiophenone

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / NaBH4 / ethanol / 3 h / 5 - 25 °C
2: 28 percent Chromat. / O2, Rose Bengal / acetonitrile / 13 °C / Irradiation
View Scheme
3-methoxy-4-benzyloxy-α-bromoacetophenone
1835-12-7

3-methoxy-4-benzyloxy-α-bromoacetophenone

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 95 percent / K2CO3 / dimethylformamide / 2 h / 25 °C
2: 1) K2CO3, 2) 1 M NaOH / 1) DMSO, 25 deg C, 10 min, 2) DMSO, H2O, 25 deg C, 1 h
3: 78 percent / NaBH4 / ethanol / 3 h / 5 - 25 °C
4: 28 percent Chromat. / O2, Rose Bengal / acetonitrile / 13 °C / Irradiation
View Scheme
1-(4-(benzyloxy)-3-methoxyphenyl)-2-(2-methoxyphenoxy)ethan-1-one
22317-29-9

1-(4-(benzyloxy)-3-methoxyphenyl)-2-(2-methoxyphenoxy)ethan-1-one

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) K2CO3, 2) 1 M NaOH / 1) DMSO, 25 deg C, 10 min, 2) DMSO, H2O, 25 deg C, 1 h
2: 78 percent / NaBH4 / ethanol / 3 h / 5 - 25 °C
3: 28 percent Chromat. / O2, Rose Bengal / acetonitrile / 13 °C / Irradiation
View Scheme
guaiacylglycerol-β-guaiacyl ether
7382-59-4

guaiacylglycerol-β-guaiacyl ether

A

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: oxygen; N-hydroxyphthalimide / acetone / 30 h / 20 °C / 760.05 Torr / Irradiation
2: N-ethyl-N,N-diisopropylamine; formic acid / acetonitrile / 24 h / 20 °C / Inert atmosphere; Irradiation
View Scheme
pinoresinol
7452-03-1

pinoresinol

A

3,4-Dihydroxybenzoic acid
99-50-3

3,4-Dihydroxybenzoic acid

B

3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

C

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
With potassium superoxide; sphingobacterium sp. T2 manganese superoxide dismutase In dimethyl sulfoxide for 1h; pH=7.8; Inert atmosphere; Enzymatic reaction;
guaiacylglycerol-β-guaiacyl ether
7382-59-4

guaiacylglycerol-β-guaiacyl ether

A

coniferol
458-35-5

coniferol

B

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C

1-(4-hydroxy-3-methoxyphenyl)-2-propene-1-one
2983-65-5

1-(4-hydroxy-3-methoxyphenyl)-2-propene-1-one

D

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With 4ZnS*In2S3 In water; acetonitrile for 20h; Inert atmosphere; UV-irradiation;
1-(4-hydroxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol
56122-34-0

1-(4-hydroxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

A

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

B

1-(4-hydroxy-3-methoxyphenyl)-2-propene-1-one
2983-65-5

1-(4-hydroxy-3-methoxyphenyl)-2-propene-1-one

C

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With 4ZnS*In2S3 In water; acetonitrile for 16h; Inert atmosphere; UV-irradiation;
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

3-chloro-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
7182-42-5

3-chloro-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

Conditions
ConditionsYield
With hydrogenchloride at 90℃; for 0.5h;96%
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-1-propanol
3063-86-3

3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-1-propanol

Conditions
ConditionsYield
With sodium tetrahydroborate; sodium hydroxide In water at 26℃; for 24h;79%
With lithium aluminium tetrahydride In diethyl ether
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

acetic anhydride
108-24-7

acetic anhydride

ω-hydroxypropioguaiacone diacetate
107682-24-6

ω-hydroxypropioguaiacone diacetate

Conditions
ConditionsYield
In pyridine for 24h; Ambient temperature;2 mg
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

3,3-bis(4-hydroxy-3-methoxyphenyl)-1-propanol

3,3-bis(4-hydroxy-3-methoxyphenyl)-1-propanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; sodium hydroxide / water / 24 h / 26 °C
2: methanesulfonic acid / water / 22.5 h / 65 °C
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

coniferol
458-35-5

coniferol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; sodium hydroxide / water / 24 h / 26 °C
2: triethylamine / isopropyl alcohol / 48 h / 85 - 90 °C
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

A

C20H32O4Si

C20H32O4Si

B

C20H32O4Si

C20H32O4Si

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: (2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; N-ethyl-N,N-diisopropylamine / toluene / 16 h / -78 °C / Inert atmosphere; Resolution of racemate
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

A

C19H26O5

C19H26O5

B

C15H20O4

C15H20O4

C

C19H26O5

C19H26O5

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: (2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; N-ethyl-N,N-diisopropylamine / toluene / 16 h / -78 °C / Inert atmosphere; Resolution of racemate
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C23H34O5Si

C23H34O5Si

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C19H32O5Si

C19H32O5Si

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
6.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
7.1: sodium acetate; hydrogen; palladium 10% on activated carbon / methanol / 12 h / 20 °C
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C19H30O5Si

C19H30O5Si

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
6.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
7.1: sodium acetate; hydrogen; palladium 10% on activated carbon / methanol / 12 h / 20 °C
8.1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C19H30O6Si

C19H30O6Si

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
6.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
7.1: sodium acetate; hydrogen; palladium 10% on activated carbon / methanol / 12 h / 20 °C
8.1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere
9.1: sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

C18H31NO4Si

C18H31NO4Si

Conditions
ConditionsYield
Multi-step reaction with 15 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
4.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
6.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
7.1: sodium acetate; hydrogen; palladium 10% on activated carbon / methanol / 12 h / 20 °C
8.1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere
9.1: sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 12 h / 20 °C / Inert atmosphere
10.1: thionyl chloride / dichloromethane / 0.75 h / 20 °C / Inert atmosphere
10.2: 1.5 h / Inert atmosphere
11.1: toluene-4-sulfonic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
12.1: boron trifluoride diethyl etherate; triethylsilane / dichloromethane / 2 h / -78 °C / Inert atmosphere
13.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere
13.2: 1 h / Inert atmosphere
14.1: sodium azide / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere
15.1: hydrogen; palladium 10% on activated carbon / ethyl acetate / 1 h / 20 °C
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

1-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)prop-2-en-1-one

1-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)prop-2-en-1-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
View Scheme
3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone
2196-18-1

3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone

1-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)prop-2-en-1-ol
1491173-73-9

1-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)prop-2-en-1-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: tetra-(n-butyl)ammonium iodide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 2 h / Inert atmosphere
2.1: dmap; 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere
3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 1 h / 0 °C / Inert atmosphere
View Scheme

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