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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 2200-91-1 with best quality

Cas:2200-91-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4-ETHYNYL-PHENOL CAS:2200-91-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

4-ETHYNYL-PHENOL CAS:2200-91-1

Cas:2200-91-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SAGECHEM LIMITED

4-Ethynyl-phenol 2200-91-1 Application:4-Ethynyl-phenol 2200-91-1

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

2200-91-1

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

4-ETHYNYL-PHENOL CAS NO.2200-91-1

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

2200-91-1

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Raymon Biotech Co., Ltd.

4-Ethynyl-phenolAppearance:liquid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shenzhen

4-Ethynyl-phenol

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 4-ETHYNYL-PHENOL, CAS:2200-91-1 with the most competitive price and the best quality.

4-ETHYNYL-PHENOL

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Jinan Trio PharmaTech Co., Ltd

Storage:Low temperature dry and shady Package:according to the request of customer Application:only for research Transportation:according to the request of customer

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

2200-91-1

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Ark Pharm, Inc.

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

CHEMSTEP

Phenol, 4-ethynyl-

Cas:2200-91-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenol
402955-91-3

4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
With potassium hydroxide In 1,4-dioxane at 120℃; for 12h;99%
4-(2-(trimethylsilyl)ethynyl)phenol
88075-18-7

4-(2-(trimethylsilyl)ethynyl)phenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In chloroform for 1h; Inert atmosphere;97%
With tetrabutyl ammonium fluoride In methanol at 20℃; for 12h;97%
With potassium carbonate In methanol at 25℃; for 3h;85%
[{4-(1,1-dimethylethyl)dimethylsiloxyphenyl}ethynyl]trimethylsilane
200625-51-0

[{4-(1,1-dimethylethyl)dimethylsiloxyphenyl}ethynyl]trimethylsilane

A

4-ethynylphenol
2200-91-1

4-ethynylphenol

B

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene
136053-34-4

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene

Conditions
ConditionsYield
With silver nitrate In water; acetone at 20℃; for 44h;A n/a
B 88%
4-Iodophenol
540-38-5

4-Iodophenol

tributylethynyltin
994-89-8

tributylethynyltin

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
diphenylphosphine-based palladium(0) complex on MCM-41 In water; N,N-dimethyl-formamide at 60℃; for 8h; Stille coupling;85%
4-Iodophenol
540-38-5

4-Iodophenol

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: p-Iodophenol; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine Sonogashira coupling;
Stage #2: With potassium carbonate In methanol
82%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 60℃; for 4h; Inert atmosphere;80%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine Yield given. Multistep reaction;
1,1-dibromo-2-(4-hydroxyphenyl)ethylene
144256-13-3

1,1-dibromo-2-(4-hydroxyphenyl)ethylene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: 1,1-dibromo-2-(4-hydroxyphenyl)ethylene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: With water In tetrahydrofuran; hexane at -78℃; for 0.5h;
81%
carbon tetrabromide
558-13-4

carbon tetrabromide

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: carbon tetrabromide With triphenylphosphine In dichloromethane at 0℃; for 0.5h; Corey-Fuchs Alkyne Synthesis;
Stage #2: 4-hydroxy-benzaldehyde In dichloromethane at 0 - 20℃; for 2h; Corey-Fuchs Alkyne Synthesis;
Stage #3: With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Corey-Fuchs Alkyne Synthesis;
80%
4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenol
402955-91-3

4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
With potassium hydroxide In 1,4-dioxane at 120℃; for 12h;99%
4-(2-(trimethylsilyl)ethynyl)phenol
88075-18-7

4-(2-(trimethylsilyl)ethynyl)phenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In chloroform for 1h; Inert atmosphere;97%
With tetrabutyl ammonium fluoride In methanol at 20℃; for 12h;97%
With potassium carbonate In methanol at 25℃; for 3h;85%
[{4-(1,1-dimethylethyl)dimethylsiloxyphenyl}ethynyl]trimethylsilane
200625-51-0

[{4-(1,1-dimethylethyl)dimethylsiloxyphenyl}ethynyl]trimethylsilane

A

4-ethynylphenol
2200-91-1

4-ethynylphenol

B

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene
136053-34-4

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene

Conditions
ConditionsYield
With silver nitrate In water; acetone at 20℃; for 44h;A n/a
B 88%
4-Iodophenol
540-38-5

4-Iodophenol

tributylethynyltin
994-89-8

tributylethynyltin

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
diphenylphosphine-based palladium(0) complex on MCM-41 In water; N,N-dimethyl-formamide at 60℃; for 8h; Stille coupling;85%
4-Iodophenol
540-38-5

4-Iodophenol

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: p-Iodophenol; trimethylsilylacetylene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine Sonogashira coupling;
Stage #2: With potassium carbonate In methanol
82%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 60℃; for 4h; Inert atmosphere;80%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine Yield given. Multistep reaction;
1,1-dibromo-2-(4-hydroxyphenyl)ethylene
144256-13-3

1,1-dibromo-2-(4-hydroxyphenyl)ethylene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: 1,1-dibromo-2-(4-hydroxyphenyl)ethylene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: With water In tetrahydrofuran; hexane at -78℃; for 0.5h;
81%
carbon tetrabromide
558-13-4

carbon tetrabromide

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Stage #1: carbon tetrabromide With triphenylphosphine In dichloromethane at 0℃; for 0.5h; Corey-Fuchs Alkyne Synthesis;
Stage #2: 4-hydroxy-benzaldehyde In dichloromethane at 0 - 20℃; for 2h; Corey-Fuchs Alkyne Synthesis;
Stage #3: With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Corey-Fuchs Alkyne Synthesis;
80%
[4-(tetrahydropyran-2-yloxy)phenyl]ethyne
119754-16-4

[4-(tetrahydropyran-2-yloxy)phenyl]ethyne

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In ethanol at 65℃; for 1h;67%
3-methyl-4-(4-hydroxyphenyl)methylene-isoxazole-5(4H)-one
103906-10-1

3-methyl-4-(4-hydroxyphenyl)methylene-isoxazole-5(4H)-one

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
at 800℃; under 0.000750075 Torr;67%
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
34.7%
4-Iodophenol
540-38-5

4-Iodophenol

anilinooxalyl azide

anilinooxalyl azide

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 65.3 percent / p-toluenesulfonis acid monohydrate / dioxane / 1.5 h
2.1: triphenylphosphine; copper(I) iodide; palladium(II) chloride / triethylamine / 0.5 h / 50 °C
2.2: 93 percent / 5 h / 85 °C
3.1: 75.4 percent / potassium hydroxide / toluene / 6 h / 100 °C
4.1: 67 percent / pyridinium p-toluenesulfonate / ethanol / 1 h / 65 °C
View Scheme
4-[(tetrahydro-2H-pyran-2-yl)oxy]iodobenzene
99522-34-6

4-[(tetrahydro-2H-pyran-2-yl)oxy]iodobenzene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triphenylphosphine; copper(I) iodide; palladium(II) chloride / triethylamine / 0.5 h / 50 °C
1.2: 93 percent / 5 h / 85 °C
2.1: 75.4 percent / potassium hydroxide / toluene / 6 h / 100 °C
3.1: 67 percent / pyridinium p-toluenesulfonate / ethanol / 1 h / 65 °C
View Scheme
1-[(tetrahydro-2H-pyran-2-yl)oxy]-4-[3-hydroxy-3-methylbut-1-ynyl]benzene
119754-13-1

1-[(tetrahydro-2H-pyran-2-yl)oxy]-4-[3-hydroxy-3-methylbut-1-ynyl]benzene

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 75.4 percent / potassium hydroxide / toluene / 6 h / 100 °C
2: 67 percent / pyridinium p-toluenesulfonate / ethanol / 1 h / 65 °C
View Scheme
t-butyldimethylsilyl-4-bromophenol
67963-68-2

t-butyldimethylsilyl-4-bromophenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 64 percent / diisopropylamine; tri(tert-butyl)phosphane; CuI / PdCl2(PhCN)2 / dioxane / 20 h / 20 °C
2: AgNO3 / acetone; H2O / 44 h / 20 °C
View Scheme
4-Iodophenol
540-38-5

4-Iodophenol

Wang resin

Wang resin

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77 percent / PPh3 / PdCl2(PPh3)2; CuI / triethylamine / 15 h / 70 °C
2: 99 percent / KOH / dioxane / 12 h / 120 °C
View Scheme
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triphenylphosphine / dichloromethane / 1 h / 0 °C
1.2: 2 h / 0 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
2.2: 0.5 h / -78 °C
View Scheme
Multi-step reaction with 2 steps
1: chloroform / 24 h / Cooling with ice; Inert atmosphere; Darkness
2: 800 °C / 0 Torr
View Scheme
4-Iodophenol
540-38-5

4-Iodophenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / triethylamine / 3 h / 80 °C / Inert atmosphere
2: sodium hydroxide; water / methanol / 3 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.33 h / Inert atmosphere
1.2: 20 h / Darkness; Inert atmosphere
2.1: tetrabutyl ammonium fluoride / chloroform / 1 h / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide
2: tetrabutyl ammonium fluoride
View Scheme
4-ethynylphenol
2200-91-1

4-ethynylphenol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene
136053-34-4

1-[(tert-butyldimethylsilyl)oxy]-4-ethynylbenzene

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;67%
In N,N-dimethyl-formamide at 20℃;
4-ethynylphenol
2200-91-1

4-ethynylphenol

C9H4ClN3O3

C9H4ClN3O3

C17H10ClN3O4

C17H10ClN3O4

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethyl 2,2,2”-(4,4’,4”-nitrilotris(methylene)tris(1H-1,2,3-triazole-4,1-diyl))triacetate In ethanol; water at 20℃; for 1h; Huisgen Cycloaddition;100%
4-ethynylphenol
2200-91-1

4-ethynylphenol

1-iodo-4-(trimethylsilylethynyl)benzene
134856-58-9

1-iodo-4-(trimethylsilylethynyl)benzene

4-(4-trimethylsilanylethynyl-phenylethynyl)-phenol
910467-75-3

4-(4-trimethylsilanylethynyl-phenylethynyl)-phenol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine In tetrahydrofuran at 25℃; Sonogashira coupling reaction;93%
4-ethynylphenol
2200-91-1

4-ethynylphenol

3-azido-7-hydroxycoumarin
817638-68-9

3-azido-7-hydroxycoumarin

C17H11N3O4

C17H11N3O4

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethyl 2,2,2”-(4,4’,4”-nitrilotris(methylene)tris(1H-1,2,3-triazole-4,1-diyl))triacetate In ethanol; water at 20℃; Huisgen Cycloaddition;92%
With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethyl 2,2,2”-(4,4’,4”-nitrilotris(methylene)tris(1H-1,2,3-triazole-4,1-diyl))triacetate In ethanol; water at 20℃; for 1h; Huisgen Cycloaddition;92%
4-ethynylphenol
2200-91-1

4-ethynylphenol

4-methyl-2-oxo-2H-chromen-7-yl-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
93131-78-3

4-methyl-2-oxo-2H-chromen-7-yl-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate

7-(2-(4-hydroxyphenyl)ethynyl)-4-methyl-2H-chromen-2-one
1600531-56-3

7-(2-(4-hydroxyphenyl)ethynyl)-4-methyl-2H-chromen-2-one

Conditions
ConditionsYield
Stage #1: 4-methyl-2-oxo-2H-chromen-7-yl-1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate With (bis(tricyclohexyl)phosphine)palladium(II) dichloride In N,N-dimethyl acetamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: 4-ethynylphenol With tetrabutyl ammonium fluoride In N,N-dimethyl acetamide at 100℃; for 0.333333h; Sonogashira Cross-Coupling; Inert atmosphere; Microwave irradiation;
91%
carbon monoxide
201230-82-2

carbon monoxide

4-ethynylphenol
2200-91-1

4-ethynylphenol

4-amino-phenol
123-30-8

4-amino-phenol

C15H13NO3

C15H13NO3

Conditions
ConditionsYield
With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; toluene-4-sulfonic acid In tetrahydrofuran; acetonitrile at 120℃; under 23272.3 Torr; for 72h; regioselective reaction;91%
2-Iodophenol
533-58-4

2-Iodophenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

1-Fluoro-3-iodobenzene
1121-86-4

1-Fluoro-3-iodobenzene

4-(3-(3-fluorophenyl)benzofuran-2-yl)phenol

4-(3-(3-fluorophenyl)benzofuran-2-yl)phenol

Conditions
ConditionsYield
Stage #1: 2-Iodophenol; 4-ethynylphenol With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In tetrahydrofuran at 40℃; for 0.5h; Microwave irradiation; Inert atmosphere;
Stage #2: 1-Fluoro-3-iodobenzene In acetonitrile at 100℃; for 0.5h; Inert atmosphere; Microwave irradiation;
91%
carbon dioxide
124-38-9

carbon dioxide

4-ethynylphenol
2200-91-1

4-ethynylphenol

3-(4-methylphenyl)prop-2-ynoic acid
2227-58-9

3-(4-methylphenyl)prop-2-ynoic acid

Conditions
ConditionsYield
With [CuI(1,1′-bis(di-tert-butylphosphino)ferrocene)]; caesium carbonate In N,N-dimethyl-formamide at 25℃; under 760.051 Torr; for 24h; Inert atmosphere;90%
4-ethynylphenol
2200-91-1

4-ethynylphenol

α-azido-4'-hydroxyacetophenone
169315-44-0

α-azido-4'-hydroxyacetophenone

Conditions
ConditionsYield
With dipotassium peroxodisulfate; trimethylsilylazide; oxygen; copper diacetate In dimethyl sulfoxide at 20 - 25℃; for 12h;89%
4-ethynylphenol
2200-91-1

4-ethynylphenol

3,4,5-tris(((S)-3,7-dimethyloctyl)oxy)benzoic acid
798567-90-5

3,4,5-tris(((S)-3,7-dimethyloctyl)oxy)benzoic acid

C45H70O5

C45H70O5

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 48h;89%
carbon monoxide
201230-82-2

carbon monoxide

4-ethynylphenol
2200-91-1

4-ethynylphenol

4-amino-phenol
123-30-8

4-amino-phenol

C15H13NO3
111527-00-5

C15H13NO3

Conditions
ConditionsYield
With 5-chloro-2-hydroxybenzoic acid; boric acid; palladium diacetate; 1,2-bis[di(t-butyl)phosphinomethyl]benzene In acetonitrile at 110℃; under 18100.7 Torr; for 48h;89%
4-ethynylphenol
2200-91-1

4-ethynylphenol

4-n-pentadecylbenzoic acid
62443-08-7

4-n-pentadecylbenzoic acid

4-ethynylphenyl 4-tetradecyloxybenzoate
142663-61-4

4-ethynylphenyl 4-tetradecyloxybenzoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 16h; Inert atmosphere; Cooling with ice;88%
4-ethynylphenol
2200-91-1

4-ethynylphenol

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

tert-butyl-(4-ethynylphenoxy)-diphenylsilane

tert-butyl-(4-ethynylphenoxy)-diphenylsilane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 24h; Inert atmosphere;88%
3-iodopyridine
1120-90-7

3-iodopyridine

2-Iodophenol
533-58-4

2-Iodophenol

4-ethynylphenol
2200-91-1

4-ethynylphenol

4-(3-(pyridin-3-yl)benzofuran-2-yl)phenol

4-(3-(pyridin-3-yl)benzofuran-2-yl)phenol

Conditions
ConditionsYield
Stage #1: 2-Iodophenol; 4-ethynylphenol With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine In tetrahydrofuran at 40℃; for 0.5h; Microwave irradiation; Inert atmosphere;
Stage #2: 3-iodopyridine In acetonitrile at 100℃; for 0.5h; Inert atmosphere; Microwave irradiation;
88%
dichloromethane
75-09-2

dichloromethane

4-ethynylphenol
2200-91-1

4-ethynylphenol

diethylamine
109-89-7

diethylamine

C13H17NO

C13H17NO

Conditions
ConditionsYield
With 4,4'-bipyridine; [nickel(II)(pyridine)4(chloride)2]; N,N,N',N'-tetramethylguanidine In acetonitrile at 70℃; for 28h; Sealed tube; Green chemistry;85%
4-ethynylphenol
2200-91-1

4-ethynylphenol

12-iodododecanol
1620155-57-8

12-iodododecanol

C39H56O10
1620155-58-9

C39H56O10

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 90℃; for 24h;84%
4-ethynylphenol
2200-91-1

4-ethynylphenol

aniline
62-53-3

aniline

p-benzoquinone
106-51-4

p-benzoquinone

4,4'-(1H-indole-2,3-diyl)diphenol
5890-93-7

4,4'-(1H-indole-2,3-diyl)diphenol

Conditions
ConditionsYield
Stage #1: 4-ethynylphenol; aniline With copper(l) chloride In methanol Inert atmosphere;
Stage #2: p-benzoquinone In methanol at 25 - 28℃; for 6h; Irradiation; Inert atmosphere; regioselective reaction;
84%
carbon monoxide
201230-82-2

carbon monoxide

4-ethynylphenol
2200-91-1

4-ethynylphenol

2-amino-5-hydroxybenzoic acid
394-31-0

2-amino-5-hydroxybenzoic acid

N-(4’-hydroxycinnamoyl)-5-hydroxyanthranilic acid

N-(4’-hydroxycinnamoyl)-5-hydroxyanthranilic acid

Conditions
ConditionsYield
With 5-chloro-2-hydroxybenzoic acid; boric acid; palladium diacetate; 1,2-bis[di(t-butyl)phosphinomethyl]benzene In acetonitrile under 18100.7 Torr; for 48h; Heating;84%
4-ethynylphenol
2200-91-1

4-ethynylphenol

C11H8N4O3

C11H8N4O3

C19H14N4O4

C19H14N4O4

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethyl 2,2,2”-(4,4’,4”-nitrilotris(methylene)tris(1H-1,2,3-triazole-4,1-diyl))triacetate In ethanol; water at 20℃; Huisgen Cycloaddition;83%
4-ethynylphenol
2200-91-1

4-ethynylphenol

4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

Conditions
ConditionsYield
With 3,4,5-trihydroxybenzoic acid; water at 60℃; for 6h; Sealed tube; Green chemistry;83%
With ethyl 2-hydroxypropionate; water at 110℃; Green chemistry;83%
With 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); water; aniline; sodium chloride at 100℃; for 1h; Microwave irradiation; Sealed tube;71%
With water
linoleic acid
60-33-3

linoleic acid

4-ethynylphenol
2200-91-1

4-ethynylphenol

(9Z,12Z)-4-methoxystyryl octadeca-9,12-dienoate

(9Z,12Z)-4-methoxystyryl octadeca-9,12-dienoate

Conditions
ConditionsYield
With [Ru(dppp)2(CH3CN)Cl][BPh4] In toluene at 110℃; for 12h; Inert atmosphere; stereoselective reaction;82%
4-ethynylphenol
2200-91-1

4-ethynylphenol

(2S,3S,4R)-N-tert-butoxycarbonyl-2-azidomethyl-3,4-O-isopropylidenepyrrolidine-3,4-diol
1415972-59-6

(2S,3S,4R)-N-tert-butoxycarbonyl-2-azidomethyl-3,4-O-isopropylidenepyrrolidine-3,4-diol

(2S,3S,4R)-N-tert-butoxycarbonyl-2-[(4-(4-hydroxyphenyl)-1H-1,2,3-triazol-1-yl)methyl]-3,4-O-isopropylidene-pyrrolidine-3,4-diol

(2S,3S,4R)-N-tert-butoxycarbonyl-2-[(4-(4-hydroxyphenyl)-1H-1,2,3-triazol-1-yl)methyl]-3,4-O-isopropylidene-pyrrolidine-3,4-diol

Conditions
ConditionsYield
With copper(l) iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide; toluene at 50℃;81%

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