High quality Purity(GC)>90%; e.e%>99% This product can be produced with dozens of kg per bacth Appearance:Colorless to light yellow liquid Storage:2-8 ℃ Application:It is key intermediate for synthesizing treprostinil Transportation:Be ca
Cas:223734-62-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Cas:223734-62-1
Min.Order:1 Gram
FOB Price: $1.0
Type:Manufacturers
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:223734-62-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:223734-62-1
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:223734-62-1
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:223734-62-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:223734-62-1
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:223734-62-1
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirybulk productionChemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical manufacturing for overseas customers, in the field of API, pharmaceutical intermediates, chemical intermediates, fine chem
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Trading Company
inquiry1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:223734-62-1
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryHigh quality / commercialize;Stable production capacity.Appearance:actual character Storage:Temperature controlled NMT 30℃ Package:As customer request Application:Used for Synthesis API and Research Transportation:Follow the MSDS
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryIt is composed of professionals with senior industry background and rich market experience. More than 90% of the personnel have chemistry, chemical, pharmaceutical or related professional knowledge. They are all rigorously trained and evaluated, and
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryReply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Quality systemWe has a sound quality management system and documents, equipped with SHIMADZU HPLC, GC chromatography and other series of testing equipment, in order to meet the quality priority principle. Quality management department is independ
Cas:223734-62-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryR & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
1-(trimethylsilyl)-O-tetrahydropyran-2-yl-1-decyn-5-(S)-ol
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol at 20℃; for 20h; |
3,4-dihydro-2H-pyran
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: TsOH*pyridine / CH2Cl2 / 15 h / 20 °C 2: BuLi / tetrahydrofuran; hexane / 15 h / 0 - 20 °C 3: NaOH / ethanol / 20 h / 20 °C View Scheme |
(S)-1-chloroheptane-2-ol
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: TsOH*pyridine / CH2Cl2 / 15 h / 20 °C 2: BuLi / tetrahydrofuran; hexane / 15 h / 0 - 20 °C 3: NaOH / ethanol / 20 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: sodium hydroxide / tert-butyl methyl ether / 18 h / 25 °C 2.1: magnesium; iodine; mercury dichloride / diethyl ether / 0 - 36 °C / Inert atmosphere 2.2: 0.5 h 3.1: pyridinium p-toluenesulfonate / dichloromethane / 24 h / 0 - 25 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydroxide / tert-butyl methyl ether / 18 h / 25 °C 2.1: n-butyllithium / tetrahydrofuran; hexane / 3.5 h / -50 - -35 °C / Inert atmosphere 2.2: 2.5 h / -40 - -20 °C 3.1: sodium hydroxide; ethanol / 2 h / 25 °C 4.1: pyridinium p-toluenesulfonate / dichloromethane / 24 h / 0 - 25 °C View Scheme | |
Multi-step reaction with 5 steps 1: sodium hydroxide / tert-butyl methyl ether / 18 h / 25 °C 2: copper(l) iodide / tetrahydrofuran / 3 h / 0 - 5 °C / Inert atmosphere 3: pyridinium p-toluenesulfonate / dichloromethane / 25 °C 4: pyridine; pyridinium perbromide hydrobromide / dichloromethane / 3 h / 0 - 5 °C 5: sodium amide / tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene / Inert atmosphere; Reflux View Scheme |
(S)-1-chloro-O-tetrahydropyran-2-yl-heptan-2-ol
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: BuLi / tetrahydrofuran; hexane / 15 h / 0 - 20 °C 2: NaOH / ethanol / 20 h / 20 °C View Scheme |
(S)-2-pentyloxirane
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: magnesium; iodine; mercury dichloride / diethyl ether / 0 - 36 °C / Inert atmosphere 1.2: 0.5 h 2.1: pyridinium p-toluenesulfonate / dichloromethane / 24 h / 0 - 25 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3.5 h / -50 - -35 °C / Inert atmosphere 1.2: 2.5 h / -40 - -20 °C 2.1: sodium hydroxide; ethanol / 2 h / 25 °C 3.1: pyridinium p-toluenesulfonate / dichloromethane / 24 h / 0 - 25 °C View Scheme | |
Multi-step reaction with 4 steps 1: copper(l) iodide / tetrahydrofuran / 3 h / 0 - 5 °C / Inert atmosphere 2: pyridinium p-toluenesulfonate / dichloromethane / 25 °C 3: pyridine; pyridinium perbromide hydrobromide / dichloromethane / 3 h / 0 - 5 °C 4: sodium amide / tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene / Inert atmosphere; Reflux View Scheme |
(5S)-dec-1-en-5-ol
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: pyridinium p-toluenesulfonate / dichloromethane / 25 °C 2: pyridine; pyridinium perbromide hydrobromide / dichloromethane / 3 h / 0 - 5 °C 3: sodium amide / tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene / Inert atmosphere; Reflux View Scheme |
3,4-dihydro-2H-pyran
(S)-Dec-1-yn-5-ol
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
With pyridinium p-toluenesulfonate In dichloromethane at 0 - 25℃; for 24h; Temperature; | 65.1 g |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine; pyridinium perbromide hydrobromide / dichloromethane / 3 h / 0 - 5 °C 2: sodium amide / tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene / Inert atmosphere; Reflux View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
With sodium amide In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene Inert atmosphere; Reflux; |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydroxide; ethanol / 2 h / 25 °C 2: pyridinium p-toluenesulfonate / dichloromethane / 24 h / 0 - 25 °C View Scheme |
2-allyl-3-methoxybenzaldehyde
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
3-methoxy-2-(2-propenyl)-α-[(5S)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-1-decynyl]benzenemethanol
Conditions | Yield |
---|---|
With ethylmagnesium bromide In tetrahydrofuran; diethyl ether at 0 - 20℃; | 92% |
2-allyl-3-methoxybenzaldehyde
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(αS)-3-methoxy-2-(2-propenyl)-α-[(5S)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-1-decynyl]benzenemethanol
Conditions | Yield |
---|---|
Stage #1: 2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran With (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine In toluene at 20℃; for 0.25h; Stage #2: 2-allyl-3-methoxybenzaldehyde In toluene for 3h; | 87% |
2-allyl-3-(carbomethoxy)benzyloxybenzaldehyde
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
C34H44O6
Conditions | Yield |
---|---|
Stage #1: 2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran With (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine In toluene at 20℃; Stage #2: 2-allyl-3-(carbomethoxy)benzyloxybenzaldehyde In toluene at 20℃; for 2h; | 84% |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Stage #1: 2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran With ethylmagnesium bromide In tetrahydrofuran; diethyl ether at 35 - 40℃; Stage #2: 2-allyl-3-benzyloxy-N-methoxy-N-methyl-benzamide In tetrahydrofuran; diethyl ether at 25℃; for 1h; Reflux; | 77.9% |
2-allyl-3-[(carbomethoxy)methoxy]benzaldehyde
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
C28H40O6
Conditions | Yield |
---|---|
Stage #1: 2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran With (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine In toluene at 20℃; Stage #2: 2-allyl-3-[(carbomethoxy)methoxy]benzaldehyde In toluene at 20℃; for 16h; | 70% |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
treprostinil
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr 7: NaBH4; aq. NaOH / ethanol / 6 h / -10 °C 8: 2162 g / TsOH / methanol / 15 h / 0 - 20 °C 9: 80 percent / Ph2PH; n-BuLi / tetrahydrofuran; hexane / 20 h / Heating 10: 100 percent / K2CO3; tetrabutylammonium bromide / acetone / 8 h / Heating 11: 83 percent / aq. KOH / methanol / 3 h / Heating View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(1R,2R,3aS,9aS)-1-[(3S)-3-hydroxyoctyl]-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr 7: NaBH4; aq. NaOH / ethanol / 6 h / -10 °C 8: 2162 g / TsOH / methanol / 15 h / 0 - 20 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(1R,2R,3aS,9aS)-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalene-2,5-diol
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr 7: NaBH4; aq. NaOH / ethanol / 6 h / -10 °C 8: 2162 g / TsOH / methanol / 15 h / 0 - 20 °C 9: 80 percent / Ph2PH; n-BuLi / tetrahydrofuran; hexane / 20 h / Heating View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
2-((1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3S)-3-hydroxyoctyl)-1H-cyclopenta[b]naphthalen-5-yloxy)acetonitrile
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr 7: NaBH4; aq. NaOH / ethanol / 6 h / -10 °C 8: 2162 g / TsOH / methanol / 15 h / 0 - 20 °C 9: 80 percent / Ph2PH; n-BuLi / tetrahydrofuran; hexane / 20 h / Heating 10: 100 percent / K2CO3; tetrabutylammonium bromide / acetone / 8 h / Heating View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(6S)-1-[3-methoxy-2-(2-propenyl)phenyl]-6-[(tetrahydro-2H-pyran-2-yl)oxy]-2-undecyn-1-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(αS)-3-methoxy-2-(2-propenyl)-α-[(5S)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-1-decynyl]benzenemethanol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
1,3,3a,4,9,9a-hexahydro-5-methoxy-1-[(3S)-3-[(tetrahydro-2H-pyran-2-yl)oxy]octyl]-2H-benz[f]inden-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-5-methoxy-1-[(3S)-3-[(tetrahydro-2H-pyran-2-yl)oxy]octyl]-1H-benz[f]inden-2-ol
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C 6: H2; K2CO3 / Pd/C / ethanol / 20 °C / 4654.33 Torr 7: NaBH4; aq. NaOH / ethanol / 6 h / -10 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(1,1-dimethylethyl)[[(1S,6S)-1-[3-methoxy-2-(2-propenyl)phenyl]-6-[(tetrahydro-2H-pyran-2-yl)oxy]-2-undecynyl]oxy]dimethylsilane
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
(3aS,9aS)-9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3a,4,9-tetrahydro-5-methoxy-1-[(3S)-3-[(tetrahydro-2H-pyran-2-yl)oxy]octyl]-2H-benz[f]inden-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C 2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C 3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C 4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C 5: CH2Cl2 / 2 h / 20 °C View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: zinc trifluoromethanesulfonate; triethylamine; (1S,2R)-(+)-N-methylephedrine 2: 1H-imidazole / dichloromethane View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: zinc trifluoromethanesulfonate; triethylamine; (1S,2R)-(+)-N-methylephedrine 2: 1H-imidazole / dichloromethane 3: Co(CO)8 / 1,2-dimethoxyethane / 3620.13 Torr View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: zinc trifluoromethanesulfonate; triethylamine; (1S,2R)-(+)-N-methylephedrine 2: 1H-imidazole / dichloromethane 3: Co(CO)8 / 1,2-dimethoxyethane / 3620.13 Torr 4: palladium on activated charcoal; hydrogen; potassium carbonate / ethanol / 4137.29 Torr View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: zinc trifluoromethanesulfonate; triethylamine; (1S,2R)-(+)-N-methylephedrine 2: 1H-imidazole / dichloromethane 3: Co(CO)8 / 1,2-dimethoxyethane / 3620.13 Torr 4: palladium on activated charcoal; hydrogen; potassium carbonate / ethanol / 4137.29 Torr 5: sodium hydroxide; sodium tetrahydroborate View Scheme |
2-[[(1S)-1-(3-butynyl)hexyl]oxy]tetrahydro-2H-pyran
Conditions | Yield |
---|---|
With (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View