Products

Refine

Country

Business Type

Certificate

Display

EAST CHEMSOURCES LIMITED

Hot Sale Aspartame Powder CAS #: 22839-47-0 Description: White powder or granules Assay(on dry basis): 98.00-102.00% Taste: Pure Transmittance: ≥95.0% Packing: 25kg fiber drum Appearance:White powder or granules Storage:in

Hot Sale Aspartame Powder

Cas:22839-47-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Hebei Sankai Chemical Technology Co., Ltd

Hebei Sankai Chemical Co., Ltd. is a scientific and technological company set of science and technology development and mass production as one of the comprehensive enterprises. Hebei Province is a professional product research and development manufac

Aspartame CAS22839-47-0

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $30.0 / 100.0

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

Factory Price Supply sweetest sweeteners Aspartame Powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, her

Factory Price Supply sweetest sweeteners Aspartame Powder

Cas:22839-47-0

Min.Order:5 Kilogram

FOB Price: $12.9 / 16.9

Type:Manufacturers

inquiry

Baoding Faithful Industry Co., Ltd.

Sales: 1.24hours to reply your E-mail 2.Market information trend share with customers Suggestion for purchase decision Reputation: 1.Implementing contract terms strictly 2.Timely solve any discrepancy or goods claims Take our responsibility for los

Aspartame

Cas:22839-47-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Lead Bio-Chemicals Co., Ltd.

English Name: Aspartame Chemical name: aspartame, alpha -L- aspartyl -L- phenylalanine methyl ester N-L- alpha day east aminoacyl -L- phenylalanine methyl ester Chemical English: L-alpha-aspartyl-L-phenylalanine methyl ester Molecular formula

Aspartame 22839-47-0

Cas:22839-47-0

Min.Order:5 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shanxi Zorui Biotechnology Co.Ltd.

Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ

Food Aspartame Sugar Substitute Powder CAS 22839-47-0

Cas:22839-47-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

SJZ THLD IMP & EXP CO LTD

we are committed to excellence.From manufacturing to packaging and delivery, we provide quality, reliability and the highest degree of customer service.Our scope of service is organized/structured around the unique needs of each client.Our mission is

Aspartame

Cas:22839-47-0

Min.Order:500 Kilogram

Negotiable

Type:Trading Company

inquiry

NANJING SUNNY PHARMATECH CO., LTD

Nanjing Sunny Pharmatech Co., Ltd has been deeply involved in the field of sweeteners for many years, providing customers around the world with high-quality and cost-effective sweetener products. Our company's supply of Aspartame has good quality

High intensity sweeteners Aspartame

Cas:22839-47-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Yuanmeng Biological Technology Co., Ltd.

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

Good Quality Aspartame CAS 22839-47-0

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2023 New Date Stevia Aspartame Sucralose Neotame Saccharin CAS 22839-47-0 Aspartame powder sweetener

Cas:22839-47-0

Min.Order:1 Metric Ton

FOB Price: $7.5

Type:Trading Company

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

Food Additives Sweeteners Aspartame

Cas:22839-47-0

Min.Order:0

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Aspartame Manufacturer/High quality/Best price/In stock

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

We are very compeitive on Aspartame.Our mfr is ISO certified for this item with HALAL document. Product Name: Aspartame CAS: 22839-47-0 MF: C14H18N2O5 MW: 294.31 EINECS: 245-261-3

factory supply ISO HALAL Aspartame

Cas:22839-47-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality l-asp-phe methyl ester supplier in China

Cas:22839-47-0

Min.Order:25 Kilogram

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Founded in 2014, as a professional international pharmaceutical corporation, headquartered in Xi'an (China), KonoChemCo., Ltd. is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, healt

Aspartame

Cas:22839-47-0

Min.Order:1 Metric Ton

FOB Price: $10.0

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------

High purity Aspartame 22839-47-0

Cas:22839-47-0

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

Factory supply magnesium aluminum silicate

Cas:22839-47-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name Aspartame CAS number 22839-47-0 Assay ≥99% Appearance White powder Capacity 200mt/year Application Food additives More information

Aspartame

Cas:22839-47-0

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Aspartame

Cas:22839-47-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price 99% Food Grade Aspartame 22839-47-0 Kosher Manufacturer

Cas:22839-47-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

22839-47-0 - Physico-chemical Properties Molecular Formula C14H18N2O5 Molar Mass 294.31 Density 1.2051 (rough estimate) Melting Point 242-248°C Boling Point 436.08°C (rough estimate

Factory high quality Aspartame

Cas:22839-47-0

Min.Order:1 Gram

FOB Price: $7.0 / 8.0

Type:Lab/Research institutions

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Aspartame

Cas:22839-47-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Aspartame

Cas:22839-47-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Aspartame CAS NO: 22839-47-0 Grade:Medical scientific research and export Molecular formula:C14H18N2O5 Molecular weight:294.3031 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Dat

Aspartame/cas:22839-47-0/Raw material spot

Cas:22839-47-0

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Aspartame Basic information Artificial sweeteners Neotame Content analysis Toxicity Use limits The maximum amount of food additives permitted maximum allowable residue limits chemical property Application Methods of produc

TIANFU-CHEM CAS:22839-47-0 Aspartame

Cas:22839-47-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Aspartame cas 22839-47-0

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 22839-47-0 with best quality

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

High quality Aspartame CAS 22839-47-0

Cas:22839-47-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Aspartame/ LIDE PHARMA- Factory supply / Best price

Cas:22839-47-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Name: Aspartame Synonyms: L-alpha-aspartyl-L-phenylalanine-methylester CAS:22839-47-0 MF: C14H18N2O5 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application: Sweeteners Transportation:B

Aspartame CAS:22839-47-0

Cas:22839-47-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Synthetic route

N-[N-[(phenylmethoxy)carbonyl]-L-α-aspartyl]-L-phenylalanine 4-(1,1-dimethylethyl) 1-methyl ester
27446-39-5

N-[N-[(phenylmethoxy)carbonyl]-L-α-aspartyl]-L-phenylalanine 4-(1,1-dimethylethyl) 1-methyl ester

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogen fluoride; methoxybenzene at 0℃; for 0.5h;98%
N-carbobenzyloxy-L-aspartyl-L-phenylalanine methyl ester
33605-72-0

N-carbobenzyloxy-L-aspartyl-L-phenylalanine methyl ester

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal97%
With hydrogen; palladium
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-(2-p-tolyl-acetylamino)-succinamic acid
140233-83-6

(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-(2-p-tolyl-acetylamino)-succinamic acid

A

4-tolylacetic acid
622-47-9

4-tolylacetic acid

B

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With penicillin amidase at 25℃; for 3.8h; Rate constant; Product distribution;A n/a
B 90%
N-phenacetyl-α-L-aspartyl-L-phenylalanine methyl ester
101623-22-7

N-phenacetyl-α-L-aspartyl-L-phenylalanine methyl ester

A

phenylacetic acid
103-82-2

phenylacetic acid

B

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With pH 7.5; penicillinacylase on Eupergit C beads In water at 28℃;A n/a
B 87%
With penicillin amidase at 25℃; for 2.5h;A n/a
B 99 % Chromat.
With penicillin amidase at 25℃; for 2.5h; Rate constant; Product distribution;A n/a
B 99 % Chromat.
α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
5910-52-1

α-L-aspartyl-L-phenylalanine methyl ester hydrochloride

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With sodium carbonate In water at 20℃; for 0.5h; pH=5;84%
With sodium carbonate In water pH=5.2;40%
methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine
40944-73-8

methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane for 0.5h;83%
With TFA-anisole
N-formylaspartame
33605-76-4

N-formylaspartame

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydroxylamine hydrochloride In methanol83%
methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

<(4S)-2,2-bis(trifluoromethyl)-5-oxo-1,3-oxazolidine-4-yl>acetate
131021-87-9

<(4S)-2,2-bis(trifluoromethyl)-5-oxo-1,3-oxazolidine-4-yl>acetate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
In diethyl ether at 20℃; for 24h;72%
In diethyl ether; ethyl acetate Ambient temperature;
4N-hydrochloric acid

4N-hydrochloric acid

N-formylaspartame
33605-76-4

N-formylaspartame

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
In water; tert-butyl alcohol70%
(S)-3-Formylamino-N-(1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid

(S)-3-Formylamino-N-(1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogenchloride In methanol for 0.5h; Heating;65%
anhydride du N-chloroacetyl-L-acide aspartique
41567-23-1

anhydride du N-chloroacetyl-L-acide aspartique

methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

A

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

B

α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
5910-52-1

α-L-aspartyl-L-phenylalanine methyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; acetic acid; thiourea; sodium chloride In methanol; 1,1-dichloroethane; waterA n/a
B 48%
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-nitro-phenyl)-acetylamino]-succinamic acid
140233-85-8

(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-nitro-phenyl)-acetylamino]-succinamic acid

A

4-nitrobenzeneacetic acid
104-03-0

4-nitrobenzeneacetic acid

B

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With penicillin amidase at 25℃; for 8.3h; Rate constant; Product distribution;A n/a
B 30%
L-aspartic anhydride hydrochloride
104413-44-7

L-aspartic anhydride hydrochloride

methyl bisulfate
75-93-4

methyl bisulfate

methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With sulfuric acid In methanol; 1,2-dichloro-ethane21.9%
L-aspartic anhydride hydrochloride
104413-44-7

L-aspartic anhydride hydrochloride

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
21.8%
n-formyl-l-aspartic anhydride
116147-62-7

n-formyl-l-aspartic anhydride

methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With potassium hydroxide; hydroxylamine hydrochloride In methanol; ethyl acetate21%
L-aspartic anhydride hydrochloride
104413-44-7

L-aspartic anhydride hydrochloride

methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
In methanol; 1,2-dichloro-ethane19.2%
Boc-Asp(OtBu)-Phe-OMe
4976-94-7

Boc-Asp(OtBu)-Phe-OMe

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With trifluoroacetic acid
Z-Asp(OBzl)-Phe-OMe
5262-07-7

Z-Asp(OBzl)-Phe-OMe

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogen; acetic acid; palladium
With hydrogenchloride; hydrogen; palladium on activated charcoal In methanol
With hydrogen; palladium on activated charcoal
With palladium on carbon; hydrogen In methanol for 4h;
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

L-aspartic acid N-thiocarboxyanhydride
77217-04-0, 82522-65-4

L-aspartic acid N-thiocarboxyanhydride

A

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

B

aspartame
25548-16-7

aspartame

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide 1.) water, 0-5 deg C, pH 8.5-9.5, 2.) MeOH, water, 0 deg C, pH 4.5-5; Yield given. Multistep reaction. Yields of byproduct given;
(S)-2-[(2-Benzyl-5-oxo-isoxazolidine-3-carbonyl)-amino]-3-phenyl-propionic acid methyl ester
125507-05-3, 125507-06-4

(S)-2-[(2-Benzyl-5-oxo-isoxazolidine-3-carbonyl)-amino]-3-phenyl-propionic acid methyl ester

A

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

B

(R)-Asp-(S)-PhOMe
22839-66-3

(R)-Asp-(S)-PhOMe

Conditions
ConditionsYield
With hydrogen; palladium dihydroxide In ethanol; water at 20℃; under 760 Torr; for 5h; Yield given. Yields of byproduct given;
With hydrogen; palladium dihydroxide In ethanol; water at 20℃; under 1 Torr; for 5h; Yield given. Yields of byproduct given;
(S)-2-{[(S)-5-Oxo-2-((R)-1-phenyl-ethyl)-isoxazolidine-3-carbonyl]-amino}-3-phenyl-propionic acid methyl ester
125507-07-5, 125590-57-0, 125590-58-1

(S)-2-{[(S)-5-Oxo-2-((R)-1-phenyl-ethyl)-isoxazolidine-3-carbonyl]-amino}-3-phenyl-propionic acid methyl ester

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogen; palladium dihydroxide In ethanol; water at 70℃; under 760 Torr; for 5h;65 mg
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-methoxy-phenyl)-acetylamino]-succinamic acid
140233-84-7

(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-methoxy-phenyl)-acetylamino]-succinamic acid

A

4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

B

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With penicillin amidase at 25℃; for 7h; Product distribution; Rate constant;A n/a
B 92 % Chromat.
(S)-3-Benzyloxycarbonylamino-N-(1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid

(S)-3-Benzyloxycarbonylamino-N-(1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal Yield given;
aspartame hemihydrate, form I, ball-milled

aspartame hemihydrate, form I, ball-milled

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
at 130℃; Kinetics;
methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetonitrile / 2 h / Ambient temperature
2: H2 / Pd
View Scheme
Multi-step reaction with 2 steps
1: 1.) pyridine, triethylamine, pivaloyl chloride; 2.) DMFA, 1-hydroxybenzotriazole / 1.) THF, 20 min, -10 deg C; 2.) CHCl3, 1.5 h 20 deg C
2: 83 percent / 4 N HCl / dioxane / 0.5 h
View Scheme
Multi-step reaction with 3 steps
1: 1.) pyridine, triethylamine, pivaloyl chloride; 2.) DMFA, 1-hydroxybenzotriazole / 1.) THF; 2.) CHCl3
2: hydrogen / Pd/C / acetic acid
3: 83 percent / 4 N HCl / dioxane / 0.5 h
View Scheme
L,L-N-t-Boc-Asp(OBz)-PM
104413-52-7

L,L-N-t-Boc-Asp(OBz)-PM

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen / Pd/C / acetic acid
2: 83 percent / 4 N HCl / dioxane / 0.5 h
View Scheme
Multi-step reaction with 2 steps
1: 66 percent / H2 / Pd / methanol; acetic acid / 3 h
2: TFA-anisole
View Scheme
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Asp-Phe-NH2
5241-71-4

Asp-Phe-NH2

Conditions
ConditionsYield
With ammonia at -40℃; for 10.25h;97%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

A

N-[(1,1-dimethylethoxy)carbonyl]-(L)-α-aspartyl-(L)-phenylalanine methyl ester mono(sodium) salt
222641-22-7

N-[(1,1-dimethylethoxy)carbonyl]-(L)-α-aspartyl-(L)-phenylalanine methyl ester mono(sodium) salt

B

N-[(1,1-dimethylethoxy)carbonyl]-(L)-α-aspartyl-(L)-phenylalanine mono(sodium) salt

N-[(1,1-dimethylethoxy)carbonyl]-(L)-α-aspartyl-(L)-phenylalanine mono(sodium) salt

Conditions
ConditionsYield
With sodium hydroxide In methanol; water; ethyl acetateA n/a
B 97%
dichloro(p-cymene)ruthenium(II) dimer

dichloro(p-cymene)ruthenium(II) dimer

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

sodium methylate
124-41-4

sodium methylate

{(η6-p-cymene)Ru(L-aspartyl-L-phenylalaninemethylester)}Cl

{(η6-p-cymene)Ru(L-aspartyl-L-phenylalaninemethylester)}Cl

Conditions
ConditionsYield
In methanol byproducts: NaCl; under Ar, addn. of 2 equivalents NaOMe-soln. to Ru-compd. and 2 equivalents of ligand in methanol, stirred for 30 min at room temp.; evapd. in vac., residue taken up in CH2Cl2, centrifuge (NaCl), dropwise addn. to pentane; elem. anal.;97%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

((L)-α-aspartyl)-(L)-phenylalaninamide ammonium salt

((L)-α-aspartyl)-(L)-phenylalaninamide ammonium salt

Conditions
ConditionsYield
With ammonia at -40℃; for 1.5h;95%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

[(2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl]acetic acid
5262-10-2

[(2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl]acetic acid

Conditions
ConditionsYield
at 200℃; for 0.333333h;92%
In dimethyl sulfoxide at 80℃; for 8h;88%
at 180℃; Kinetics;
methanol
67-56-1

methanol

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

N-α-L-aspartyl-L-phenylalanine dimethyl ester hydrochloride

N-α-L-aspartyl-L-phenylalanine dimethyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 25℃; Schlenk technique; Inert atmosphere;91%
nicotinoyl azide
4013-72-3

nicotinoyl azide

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

Nα-nicotinoyl-L-aspartyl-L-phenylalanine methyl ester

Nα-nicotinoyl-L-aspartyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0℃; for 3h;90%
(2R, 4R)-monatin sodium salt

(2R, 4R)-monatin sodium salt

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

mixed crystals (salt) of (2R,4R)-monatin and aspartame

mixed crystals (salt) of (2R,4R)-monatin and aspartame

Conditions
ConditionsYield
With hydrogenchloride In water at 50℃; for 0.166667h;87.2%
dichloro(p-cymene)ruthenium(II) dimer

dichloro(p-cymene)ruthenium(II) dimer

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

sodium methylate
124-41-4

sodium methylate

(η6-p-cymene)Ru(L-aspartyl-L-phenylalaninemethylester(2-))*H2O

(η6-p-cymene)Ru(L-aspartyl-L-phenylalaninemethylester(2-))*H2O

Conditions
ConditionsYield
In methanol byproducts: NaCl; under Ar, addn. of 4 equivalents NaOMe-soln. to Ru-compd. and 2 equivalents of ligand in methanol, stirred for 1.5 h min at room temp.; evapd. in vac., residue taken up in CH2Cl2, centrifuge (NaCl), dropwise addn. to pentane, diffusion of ether into a methanolic soln.; elem. anal.;86%
3,3-dimethylbutyrylaldehyde
2987-16-8

3,3-dimethylbutyrylaldehyde

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

neotame
165450-17-9

neotame

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In methanol; water at 20℃; for 6h;85%
With hydrogen; palladium on activated charcoal under 1551.44 Torr; for 12h; Condensation; reduction; room t.;56%
With hydrogen; palladium on activated charcoal In methanol at 20℃; under 1551.44 Torr; for 12h; Hydrogenation; reductive alkylation;56%
3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde
76678-64-3

3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

N-[N-[3-(3-hydroxy-4-methoxyphenyl)propenyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

N-[N-[3-(3-hydroxy-4-methoxyphenyl)propenyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate; acetic acid at 10 - 20℃; for 2h;85%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

L-phenylalanine
63-91-2

L-phenylalanine

Conditions
ConditionsYield
With sodium hydroxide for 6h; Heating;83%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

(1,1,1-trifluoroethyl) phenyl iodonium (N,N'-bis-trifluoromethylsulfonyl) imide
307501-98-0

(1,1,1-trifluoroethyl) phenyl iodonium (N,N'-bis-trifluoromethylsulfonyl) imide

L-Asp-L-Phe-OMe

L-Asp-L-Phe-OMe

Conditions
ConditionsYield
80%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

sodium 3-benzyl-6-(carboxylatomethyl)-2,5-dioxopiperazine
136983-81-8

sodium 3-benzyl-6-(carboxylatomethyl)-2,5-dioxopiperazine

Conditions
ConditionsYield
With sodium hydroxide In water78%
3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde
76678-64-3

3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

N-[N-[3-(3-benzyloxy-4-methoxyphenyl)propenyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

N-[N-[3-(3-benzyloxy-4-methoxyphenyl)propenyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate; acetic acid at 10℃;78%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine
40944-73-8

methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water at 20℃; for 18h;72%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

2-azido-α-L-aspartyl-L-phenylalanine methyl ester

2-azido-α-L-aspartyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; triflic azide; potassium carbonate; sodium hydroxide In methanol; dichloromethane; water at 20℃; for 18h; pH=9 - 9.5;70%
L-Asp-L-Phe-OMe
22839-47-0

L-Asp-L-Phe-OMe

(3-hydroxy-4-methoxy)cinnamaldehyde

(3-hydroxy-4-methoxy)cinnamaldehyde

N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L-aspartyl]-L-phenylalanine-1-methyl ester

Conditions
ConditionsYield
Stage #1: L-Asp-L-Phe-OMe; 3-hydroxy-4-methoxycinnamalaldehyde With sodium tetrahydroborate; acetic acid at 10 - 20℃; for 2h;
Stage #2: With 5%-palladium/activated carbon; hydrogen In ethanol; water under 2585.81 Torr; for 10h;
66%
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View