Hot Sale Aspartame Powder CAS #: 22839-47-0 Description: White powder or granules Assay(on dry basis): 98.00-102.00% Taste: Pure Transmittance: ≥95.0% Packing: 25kg fiber drum Appearance:White powder or granules Storage:in
Hebei Sankai Chemical Co., Ltd. is a scientific and technological company set of science and technology development and mass production as one of the comprehensive enterprises. Hebei Province is a professional product research and development manufac
Cas:22839-47-0
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inquiryFactory Price Supply sweetest sweeteners Aspartame Powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, her
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inquirySales: 1.24hours to reply your E-mail 2.Market information trend share with customers Suggestion for purchase decision Reputation: 1.Implementing contract terms strictly 2.Timely solve any discrepancy or goods claims Take our responsibility for los
English Name: Aspartame Chemical name: aspartame, alpha -L- aspartyl -L- phenylalanine methyl ester N-L- alpha day east aminoacyl -L- phenylalanine methyl ester Chemical English: L-alpha-aspartyl-L-phenylalanine methyl ester Molecular formula
Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ
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inquirywe are committed to excellence.From manufacturing to packaging and delivery, we provide quality, reliability and the highest degree of customer service.Our scope of service is organized/structured around the unique needs of each client.Our mission is
Nanjing Sunny Pharmatech Co., Ltd has been deeply involved in the field of sweeteners for many years, providing customers around the world with high-quality and cost-effective sweetener products. Our company's supply of Aspartame has good quality
Cas:22839-47-0
Min.Order:1 Kilogram
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inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:22839-47-0
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:22839-47-0
Min.Order:1 Metric Ton
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inquiry1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:22839-47-0
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWe are very compeitive on Aspartame.Our mfr is ISO certified for this item with HALAL document. Product Name: Aspartame CAS: 22839-47-0 MF: C14H18N2O5 MW: 294.31 EINECS: 245-261-3
Cas:22839-47-0
Min.Order:1 Kilogram
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:22839-47-0
Min.Order:25 Kilogram
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inquiryFounded in 2014, as a professional international pharmaceutical corporation, headquartered in Xi'an (China), KonoChemCo., Ltd. is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, healt
Items Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------
Cas:22839-47-0
Min.Order:1 Gram
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inquiryHebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
Cas:22839-47-0
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inquiryProduct description: Product name Aspartame CAS number 22839-47-0 Assay ≥99% Appearance White powder Capacity 200mt/year Application Food additives More information
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:22839-47-0
Min.Order:1 Gram
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inquiry22839-47-0 - Physico-chemical Properties Molecular Formula C14H18N2O5 Molar Mass 294.31 Density 1.2051 (rough estimate) Melting Point 242-248°C Boling Point 436.08°C (rough estimate
Cas:22839-47-0
Min.Order:1 Gram
FOB Price: $7.0 / 8.0
Type:Lab/Research institutions
inquiryColorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Name:Aspartame CAS NO: 22839-47-0 Grade:Medical scientific research and export Molecular formula:C14H18N2O5 Molecular weight:294.3031 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Dat
Cas:22839-47-0
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryAspartame Basic information Artificial sweeteners Neotame Content analysis Toxicity Use limits The maximum amount of food additives permitted maximum allowable residue limits chemical property Application Methods of produc
Cas:22839-47-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
Cas:22839-47-0
Min.Order:1 Kilogram
FOB Price: $48.0 / 58.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:22839-47-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:22839-47-0
Min.Order:10 Kilogram
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Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:22839-47-0
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inquiryName: Aspartame Synonyms: L-alpha-aspartyl-L-phenylalanine-methylester CAS:22839-47-0 MF: C14H18N2O5 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application: Sweeteners Transportation:B
N-[N-[(phenylmethoxy)carbonyl]-L-α-aspartyl]-L-phenylalanine 4-(1,1-dimethylethyl) 1-methyl ester
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogen fluoride; methoxybenzene at 0℃; for 0.5h; | 98% |
N-carbobenzyloxy-L-aspartyl-L-phenylalanine methyl ester
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal | 97% |
With hydrogen; palladium |
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-(2-p-tolyl-acetylamino)-succinamic acid
A
4-tolylacetic acid
B
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With penicillin amidase at 25℃; for 3.8h; Rate constant; Product distribution; | A n/a B 90% |
N-phenacetyl-α-L-aspartyl-L-phenylalanine methyl ester
A
phenylacetic acid
B
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With pH 7.5; penicillinacylase on Eupergit C beads In water at 28℃; | A n/a B 87% |
With penicillin amidase at 25℃; for 2.5h; | A n/a B 99 % Chromat. |
With penicillin amidase at 25℃; for 2.5h; Rate constant; Product distribution; | A n/a B 99 % Chromat. |
α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With sodium carbonate In water at 20℃; for 0.5h; pH=5; | 84% |
With sodium carbonate In water pH=5.2; | 40% |
methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane for 0.5h; | 83% |
With TFA-anisole |
N-formylaspartame
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydroxylamine hydrochloride In methanol | 83% |
methyl (2S)-2-amino-3-phenylpropanoate
<(4S)-2,2-bis(trifluoromethyl)-5-oxo-1,3-oxazolidine-4-yl>acetate
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
In diethyl ether at 20℃; for 24h; | 72% |
In diethyl ether; ethyl acetate Ambient temperature; |
Conditions | Yield |
---|---|
In water; tert-butyl alcohol | 70% |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogenchloride In methanol for 0.5h; Heating; | 65% |
anhydride du N-chloroacetyl-L-acide aspartique
methyl (2S)-2-amino-3-phenylpropanoate
A
L-Asp-L-Phe-OMe
B
α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; acetic acid; thiourea; sodium chloride In methanol; 1,1-dichloroethane; water | A n/a B 48% |
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-nitro-phenyl)-acetylamino]-succinamic acid
A
4-nitrobenzeneacetic acid
B
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With penicillin amidase at 25℃; for 8.3h; Rate constant; Product distribution; | A n/a B 30% |
L-aspartic anhydride hydrochloride
methyl bisulfate
methyl (2S)-2-amino-3-phenylpropanoate
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With sulfuric acid In methanol; 1,2-dichloro-ethane | 21.9% |
L-aspartic anhydride hydrochloride
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
21.8% |
n-formyl-l-aspartic anhydride
methyl (2S)-2-amino-3-phenylpropanoate
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With potassium hydroxide; hydroxylamine hydrochloride In methanol; ethyl acetate | 21% |
L-aspartic anhydride hydrochloride
methyl (2S)-2-amino-3-phenylpropanoate
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
In methanol; 1,2-dichloro-ethane | 19.2% |
Boc-Asp(OtBu)-Phe-OMe
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With trifluoroacetic acid |
Z-Asp(OBzl)-Phe-OMe
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogen; acetic acid; palladium | |
With hydrogenchloride; hydrogen; palladium on activated charcoal In methanol | |
With hydrogen; palladium on activated charcoal | |
With palladium on carbon; hydrogen In methanol for 4h; |
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
L-aspartic acid N-thiocarboxyanhydride
A
L-Asp-L-Phe-OMe
B
aspartame
Conditions | Yield |
---|---|
With hydrogenchloride; sodium hydroxide 1.) water, 0-5 deg C, pH 8.5-9.5, 2.) MeOH, water, 0 deg C, pH 4.5-5; Yield given. Multistep reaction. Yields of byproduct given; |
(S)-2-[(2-Benzyl-5-oxo-isoxazolidine-3-carbonyl)-amino]-3-phenyl-propionic acid methyl ester
A
L-Asp-L-Phe-OMe
B
(R)-Asp-(S)-PhOMe
Conditions | Yield |
---|---|
With hydrogen; palladium dihydroxide In ethanol; water at 20℃; under 760 Torr; for 5h; Yield given. Yields of byproduct given; | |
With hydrogen; palladium dihydroxide In ethanol; water at 20℃; under 1 Torr; for 5h; Yield given. Yields of byproduct given; |
(S)-2-{[(S)-5-Oxo-2-((R)-1-phenyl-ethyl)-isoxazolidine-3-carbonyl]-amino}-3-phenyl-propionic acid methyl ester
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogen; palladium dihydroxide In ethanol; water at 70℃; under 760 Torr; for 5h; | 65 mg |
(S)-N-((S)-1-Methoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-methoxy-phenyl)-acetylamino]-succinamic acid
A
4-Methoxyphenylacetic acid
B
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With penicillin amidase at 25℃; for 7h; Product distribution; Rate constant; | A n/a B 92 % Chromat. |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal Yield given; |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
at 130℃; Kinetics; |
methyl (2S)-2-amino-3-phenylpropanoate
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: acetonitrile / 2 h / Ambient temperature 2: H2 / Pd View Scheme | |
Multi-step reaction with 2 steps 1: 1.) pyridine, triethylamine, pivaloyl chloride; 2.) DMFA, 1-hydroxybenzotriazole / 1.) THF, 20 min, -10 deg C; 2.) CHCl3, 1.5 h 20 deg C 2: 83 percent / 4 N HCl / dioxane / 0.5 h View Scheme | |
Multi-step reaction with 3 steps 1: 1.) pyridine, triethylamine, pivaloyl chloride; 2.) DMFA, 1-hydroxybenzotriazole / 1.) THF; 2.) CHCl3 2: hydrogen / Pd/C / acetic acid 3: 83 percent / 4 N HCl / dioxane / 0.5 h View Scheme |
L,L-N-t-Boc-Asp(OBz)-PM
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogen / Pd/C / acetic acid 2: 83 percent / 4 N HCl / dioxane / 0.5 h View Scheme | |
Multi-step reaction with 2 steps 1: 66 percent / H2 / Pd / methanol; acetic acid / 3 h 2: TFA-anisole View Scheme |
L-Asp-L-Phe-OMe
Asp-Phe-NH2
Conditions | Yield |
---|---|
With ammonia at -40℃; for 10.25h; | 97% |
di-tert-butyl dicarbonate
L-Asp-L-Phe-OMe
A
N-[(1,1-dimethylethoxy)carbonyl]-(L)-α-aspartyl-(L)-phenylalanine methyl ester mono(sodium) salt
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; water; ethyl acetate | A n/a B 97% |
L-Asp-L-Phe-OMe
sodium methylate
Conditions | Yield |
---|---|
In methanol byproducts: NaCl; under Ar, addn. of 2 equivalents NaOMe-soln. to Ru-compd. and 2 equivalents of ligand in methanol, stirred for 30 min at room temp.; evapd. in vac., residue taken up in CH2Cl2, centrifuge (NaCl), dropwise addn. to pentane; elem. anal.; | 97% |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With ammonia at -40℃; for 1.5h; | 95% |
L-Asp-L-Phe-OMe
[(2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl]acetic acid
Conditions | Yield |
---|---|
at 200℃; for 0.333333h; | 92% |
In dimethyl sulfoxide at 80℃; for 8h; | 88% |
at 180℃; Kinetics; |
methanol
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With thionyl chloride at 0 - 25℃; Schlenk technique; Inert atmosphere; | 91% |
nicotinoyl azide
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 0℃; for 3h; | 90% |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With hydrogenchloride In water at 50℃; for 0.166667h; | 87.2% |
L-Asp-L-Phe-OMe
sodium methylate
Conditions | Yield |
---|---|
In methanol byproducts: NaCl; under Ar, addn. of 4 equivalents NaOMe-soln. to Ru-compd. and 2 equivalents of ligand in methanol, stirred for 1.5 h min at room temp.; evapd. in vac., residue taken up in CH2Cl2, centrifuge (NaCl), dropwise addn. to pentane, diffusion of ether into a methanolic soln.; elem. anal.; | 86% |
Conditions | Yield |
---|---|
With hydrogen; palladium 10% on activated carbon In methanol; water at 20℃; for 6h; | 85% |
With hydrogen; palladium on activated charcoal under 1551.44 Torr; for 12h; Condensation; reduction; room t.; | 56% |
With hydrogen; palladium on activated charcoal In methanol at 20℃; under 1551.44 Torr; for 12h; Hydrogenation; reductive alkylation; | 56% |
3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With sodium tetrahydroborate; acetic acid at 10 - 20℃; for 2h; | 85% |
L-Asp-L-Phe-OMe
L-phenylalanine
Conditions | Yield |
---|---|
With sodium hydroxide for 6h; Heating; | 83% |
L-Asp-L-Phe-OMe
(1,1,1-trifluoroethyl) phenyl iodonium (N,N'-bis-trifluoromethylsulfonyl) imide
Conditions | Yield |
---|---|
80% |
L-Asp-L-Phe-OMe
sodium 3-benzyl-6-(carboxylatomethyl)-2,5-dioxopiperazine
Conditions | Yield |
---|---|
With sodium hydroxide In water | 78% |
3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With sodium tetrahydroborate; acetic acid at 10℃; | 78% |
di-tert-butyl dicarbonate
L-Asp-L-Phe-OMe
methyl ester of N-tert-butyloxycarbonyl-L-aspartyl-L-phenylalanine
Conditions | Yield |
---|---|
With triethylamine In 1,4-dioxane; water at 20℃; for 18h; | 72% |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
With copper(ll) sulfate pentahydrate; triflic azide; potassium carbonate; sodium hydroxide In methanol; dichloromethane; water at 20℃; for 18h; pH=9 - 9.5; | 70% |
L-Asp-L-Phe-OMe
Conditions | Yield |
---|---|
Stage #1: L-Asp-L-Phe-OMe; 3-hydroxy-4-methoxycinnamalaldehyde With sodium tetrahydroborate; acetic acid at 10 - 20℃; for 2h; Stage #2: With 5%-palladium/activated carbon; hydrogen In ethanol; water under 2585.81 Torr; for 10h; | 66% |
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