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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-FURO[3,2-B]PYRIDINE-6-CARBONITRILE

Cas:247098-18-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

Cas:247098-18-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide Manufacturer Factory CAS 247098-18-6 3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide Manufacturer Factory CAS 247098-18-6 3-Ethyl-2,5-Dih

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 247098-18-6 with best quality

Cas:247098-18-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide CAS:247098-18-6

Cas:247098-18-6

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)- 247098-18-6

Cas:247098-18-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

Qingdao Beluga Import and Export Co., LTD

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide CAS:247098-18-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemica

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide CAS:247098-18-6

Cas:247098-18-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

Cas:247098-18-6

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

3-ethyl-4-methyl-2-oxo-3-pyrroline-1-(N-phenylethyl)carboxamide

Cas:247098-18-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-Ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-1H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzene

Cas:247098-18-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

Cas:247098-18-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermediates Trans

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing HuaNuo Bio-Pharmacuetical Co.,Ltd

Independent research and development of impurities, familiar with the market and impurity characteristics; We can ship out on the same day if the products are in stock; Focus on impurity development of new products in the market; Expert in customizi

Glimepiride Impurity 7

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystals powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-FURO[3,2-B]PYRIDINE-6-CARBONITRILEAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:An important raw material and intermediate used in Organic

2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-FURO[3,2-B]PYRIDINE-6-CARBONITRILE

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide Application:4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

4-ethyl-3-methyl-5-oxo-N-(2-phenylethyl)-2H-pyrrole-1-carboxamide

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Fandachem Co.,Ltd

1H-Pyrrole-1-carboxamide,3-ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea,

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Ethyl-2,5-Dihydro-4-Methyl-2-Oxo-N-(2-Phenylethyl)-1h-Pyrrole-1-Carboxamide

Cas:247098-18-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3-ethyl-4-methyl-3-pyrrolin-2-one
766-36-9

3-ethyl-4-methyl-3-pyrrolin-2-one

phenethyl isocyanate
1943-82-4

phenethyl isocyanate

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
In toluene at 120 - 130℃; for 2h; Industrial scale;97%
In n-heptane at 70 - 100℃; for 7h; Temperature;90%
In toluene for 4h; Molecular sieve; Reflux; Inert atmosphere;80%
In toluene Heating;65%
In toluene for 4h; Heating / reflux;
3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamide

3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamide

2-phenylethyl chloride
622-24-2

2-phenylethyl chloride

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
With copper(l) iodide; sodium hydroxide In Petroleum ether at 85℃; for 9h; Temperature;85.24%
With copper(l) iodide; sodium hydroxide In Petroleum ether at 85℃; for 9h; Temperature;85.24%
1-acetyl-3-ethyl-4-methyl-1,5-dihydro-pyrrol-2-one
61892-80-6

1-acetyl-3-ethyl-4-methyl-1,5-dihydro-pyrrol-2-one

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / Na2CO3; H2O / Heating
2: 65 percent / toluene / Heating
View Scheme
ethyl-α-ethylacetoacetate cyanohydrin
247098-17-5

ethyl-α-ethylacetoacetate cyanohydrin

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 15 percent / H2; Ac2O / Ra-Ni / 40 °C / 3800 Torr
2: 90 percent / Na2CO3; H2O / Heating
3: 65 percent / toluene / Heating
View Scheme
ethyl 2-ethyl-3-oxobutanoate
607-97-6

ethyl 2-ethyl-3-oxobutanoate

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 80 percent / dimethylformamide / 0 - 5 °C
2: 15 percent / H2; Ac2O / Ra-Ni / 40 °C / 3800 Torr
3: 90 percent / Na2CO3; H2O / Heating
4: 65 percent / toluene / Heating
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

4-{2-[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carbonyl)amino]ethyl}benzene-1-sulfonic acid

4-{2-[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carbonyl)amino]ethyl}benzene-1-sulfonic acid

Conditions
ConditionsYield
With chlorosulfonic acid In tetrahydrofuran at 20℃; Temperature;88.15%
With chlorosulfonic acid In tetrahydrofuran at 20℃; Temperature;88.15%
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

4-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]benzenesulfonyl chloride
119043-16-2

4-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]benzenesulfonyl chloride

Conditions
ConditionsYield
With chlorosulfonic acid at 10℃;
With chlorosulfonic acid at 15 - 35℃; for 4.5 - 6.5h;
With chlorosulfonic acid In dichloromethane at -5 - 30℃;
With chlorosulfonic acid at 80℃; for 0.5h;
With chlorosulfonic acid In dichloromethane at 30 - 35℃; for 5.5h; Inert atmosphere;
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
119018-29-0

N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / tetrahydrofuran / 20 °C
2: ammonia / 1,4-dioxane / 35 °C
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / dichloromethane / -5 - 30 °C
2: ammonium hydroxide / methanol / 2 h / 20 - 30 °C / Industrial scale
View Scheme
Multi-step reaction with 2 steps
1: chlorosulfonic acid / dichloromethane / 5.5 h / 30 - 35 °C / Inert atmosphere
2: ammonium hydroxide / 16 h / 20 °C
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

trans-hydroxyglimepiride

trans-hydroxyglimepiride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
3: 80 percent / K2CO3 / acetone / 8 h / Heating
4: BF3*OEt2 / CH2Cl2 / 0 °C
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

cis-hydroxyglimepiride

cis-hydroxyglimepiride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
3: 80 percent / K2CO3 / acetone / 8 h / Heating
4: BF3*OEt2 / CH2Cl2 / 0 °C
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

C32H42N4O7S
599174-28-4

C32H42N4O7S

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ClSO3H / 10 °C
2: NH3 / H2O / 4 h / 60 °C
3: 80 percent / K2CO3 / acetone / 8 h / Heating
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

glimepiride
93479-97-1

glimepiride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chlorosulfonic acid / tetrahydrofuran / 20 °C
2: ammonia / 1,4-dioxane / 35 °C
3: cyclohexanone; tert-butyl methyl ether / 10 h / 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: chlorosulfonic acid / dichloromethane / 5.5 h / 30 - 35 °C / Inert atmosphere
2.1: ammonium hydroxide / 16 h / 20 °C
3.1: potassium carbonate / acetone; butanone / 0.5 h / Inert atmosphere; Reflux
3.2: Inert atmosphere; Reflux
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

glimepiride
93479-97-1

glimepiride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: chlorosulfonic acid / dichloromethane / -5 - 30 °C
2.1: ammonium hydroxide / methanol / 2 h / 20 - 30 °C / Industrial scale
3.1: potassium carbonate / acetonitrile / 6 h / 50 - 60 °C
3.2: 4 h / 70 - 75 °C
View Scheme
3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
247098-18-6

3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide

A

C16H21N3O4S

C16H21N3O4S

B

C16H21N3O4S

C16H21N3O4S

Conditions
ConditionsYield
Stage #1: 3-ethyl-4-methyl-2-oxo-N-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide With chlorosulfonic acid at 10 - 50℃; for 8h;
Stage #2: With ammonium hydroxide at 20 - 40℃; for 8h;
A 2.8 g
B 2.2 g

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