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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Oleocanthal CAS 289030-99-5

Cas:289030-99-5

Min.Order:1 Kilogram

FOB Price: $6.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

4-Hexenoic acid, 4-formyl-3-(2-oxoethyl)-, 2-(4-hydroxyphenyl)ethyl ester, (3S,4E)-

Cas:289030-99-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Oleocanthal CAS:289030-99-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

Oleocanthal CAS:289030-99-5

Cas:289030-99-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

best price,best quality and fast delivery assurance available in sample product and customization with years of export experience along with excellent quality, advanced services and competitive prices the quality of products conform u

supply high quality (-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 289030-99-5 (-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Hexenoic acid, 4-formyl-3-(2-oxoethyl)-, 2-(4-hydroxyphenyl)ethyl ester, (3S,4E)-

Cas:289030-99-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4-Hexenoic acid, 4-formyl-3-(2-oxoethyl)-, 2-(4-hydroxyphenyl)ethyl ester, (3S,4E)-

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(-)- Oleocanthal

Cas:289030-99-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

ProName: (-)-Oleocanthal CAS NO.289030-99-5 CasNo: 289030-99-5 Molecular Formula: C17H20O5 Appearance: crystal, powder Application: Pharmaceutical intermediates DeliveryTime: 1-2 days PackAge: as your request Port: shanghai ProductionCapaci

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Gram

FOB Price: $5.0 / 6.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-(4-hydroxyphenyl)ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate

Cas:289030-99-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

Organic Intermediate Oleocanthal CAS 289030-99-5

Cas:289030-99-5

Min.Order:1 Liter

FOB Price: $4.5 / 5.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Oleocanthal

Cas:289030-99-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Oleocanthal

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Oleocanthal

Cas:289030-99-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Oleocanthal

Cas:289030-99-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, higher purity,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, s

(-)-Oleocanthal CAS NO.289030-99-5

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

Oleocanthal

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Oleocanthal

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

Oleocanthal

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

4-Hexenoic acid, 4-formyl-3-(2-oxoethyl)-, 2-(4-hydroxyphenyl)ethyl ester, (3S,4E)-

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Application:Pharmaceutical Intermediates

4-Hexenoic acid, 4-formyl-3-(2-oxoethyl)-, 2-(4-hydroxyphenyl)ethyl ester, (3S,4E)-

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

Oleocanthal

Cas:289030-99-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid 4-hydroxyphenethyl ester
869476-96-0

[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid 4-hydroxyphenethyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Stage #1: [(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid 4-hydroxyphenethyl ester With hydrogenchloride In acetonitrile
Stage #2: With sodium iodite In acetonitrile
75%
Multi-step reaction with 2 steps
1: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
2: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 2 steps
1: HCl / acetonitrile / 1 h / 20 °C
2: 20 mg / NaIO4 / CH2Cl2; H2O / 0 - 20 °C
View Scheme
[(1S,3S,4R)-2-Eth-(E)-ylidene-3,4-dihydroxy-cyclopentyl]-acetic acid 2-(4-hydroxy-phenyl)-ethyl ester
944340-53-8

[(1S,3S,4R)-2-Eth-(E)-ylidene-3,4-dihydroxy-cyclopentyl]-acetic acid 2-(4-hydroxy-phenyl)-ethyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
With sodium periodate In dichloromethane at 0℃; for 1.25h;45%
With sodium periodate In dichloromethane; water at 0 - 20℃;20 mg
With sodium periodate In tetrahydrofuran; water at 0 - 23℃; for 0.75h;66 mg
(2S,4S,E)-3-ethylidene-4-(2-(4-hydroxyphenethoxy)-2-oxoethyl)-2-{[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-3,4dihydro-2H-pyran-5-carboxylic acid

(2S,4S,E)-3-ethylidene-4-(2-(4-hydroxyphenethoxy)-2-oxoethyl)-2-{[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-3,4dihydro-2H-pyran-5-carboxylic acid

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
With β-glucosidase In aq. acetate buffer at 37℃; for 3h; pH=5; Enzymatic reaction;33%
((3aR,5S,6aR)-2,2-dimethyl-4-oxotetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl)acetic acid methyl ester
869476-93-7

((3aR,5S,6aR)-2,2-dimethyl-4-oxotetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl)acetic acid methyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
2: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
3: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
4: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
5: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 6 steps
1: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
2: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
3: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
4: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
5: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
6: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid methyl ester
869476-94-8

[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid methyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
2: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
3: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
4: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 5 steps
1: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
2: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
3: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
4: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
5: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid
869476-95-9

[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
2: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
3: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 4 steps
1: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
2: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
3: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
4: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 3 steps
1: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C
2: HCl / acetonitrile / 1 h / 20 °C
3: 20 mg / NaIO4 / CH2Cl2; H2O / 0 - 20 °C
View Scheme
[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid 2-[4-(tert-butyldimethylsilyloxy)phenyl]ethyl ester
951377-85-8

[(3aS,4E,5S,6aR)-4-ethylidene-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-yl]acetic acid 2-[4-(tert-butyldimethylsilyloxy)phenyl]ethyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
2: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
3: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
2: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
3: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
(3aR,6aR)-2,2-Dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one
115509-13-2

(3aR,6aR)-2,2-Dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 95 percent / hydrogen / Pd/C / ethyl acetate / 20 °C
2: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
3: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
4: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
5: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
6: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
7: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 8 steps
1: 95 percent / hydrogen / Pd/C / ethyl acetate / 20 °C
2: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
3: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
4: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
5: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
6: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
7: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
8: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
2-(4{[tert-butyl(dimethyl)silyl]oxy}phenyl)ethanol
96013-75-1

2-(4{[tert-butyl(dimethyl)silyl]oxy}phenyl)ethanol

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
2: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
3: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
4: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
(4R,5R)-1-(2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)prop-2-en-1-ol
683276-43-9

(4R,5R)-1-(2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)prop-2-en-1-ol

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: Grubbs catalyst / CH2Cl2 / 4 h / 23 °C
1.2: 87 percent / pyridinium chlorochromate / CH2Cl2 / 12 h / 23 °C
2.1: 95 percent / hydrogen / Pd/C / ethyl acetate / 20 °C
3.1: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
4.1: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
5.1: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
6.1: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
7.1: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
8.1: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 9 steps
1.1: Grubbs catalyst / CH2Cl2 / 4 h / 23 °C
1.2: 87 percent / pyridinium chlorochromate / CH2Cl2 / 12 h / 23 °C
2.1: 95 percent / hydrogen / Pd/C / ethyl acetate / 20 °C
3.1: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
4.1: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
5.1: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
6.1: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
7.1: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
8.1: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
9.1: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
(3aR,6aR)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-one
595581-64-9

(3aR,6aR)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-one

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
2: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
3: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
4: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran
5: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
6: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
Multi-step reaction with 7 steps
1: 57 percent / LHMDS; HMPA; Me2Zn / tetrahydrofuran; toluene / -78 - -45 °C
2: KHMDS; CeCl3 / tetrahydrofuran / -45 °C
3: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
4: 87 percent / N,N'-dicyclohexylcarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 0 - 23 °C
5: tetrabutylammonium fluoride; hydrofluoric acid / tetrahydrofuran; H2O / 0 °C / pH 6.5 - 7.0
6: aq. HCl / acetonitrile; H2O / 0.75 h / 23 °C
7: 66 mg / NaIO4 / tetrahydrofuran; H2O / 0.75 h / 0 - 23 °C
View Scheme
[(3aS,5S,6aR)-4-Eth-(E)-ylidene-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-5-yl]-acetic acid methyl ester

[(3aS,5S,6aR)-4-Eth-(E)-ylidene-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-5-yl]-acetic acid methyl ester

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / LiOH / tetrahydrofuran; methanol; H2O / 20 °C
2: 92 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C
3: HCl / acetonitrile / 1 h / 20 °C
4: 20 mg / NaIO4 / CH2Cl2; H2O / 0 - 20 °C
View Scheme
C20H26O5

C20H26O5

A

Oleocanthal
289030-99-5

Oleocanthal

B

(3S,Z)-oleocanthal

(3S,Z)-oleocanthal

Conditions
ConditionsYield
Stage #1: C20H26O5 With hydrogenchloride In acetonitrile
Stage #2: With sodium periodate
(2S,4S,E)-4-(carboxymethyl)-3-ethylidene-2-{[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylic acid
178600-68-5

(2S,4S,E)-4-(carboxymethyl)-3-ethylidene-2-{[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylic acid

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / ethyl acetate / 0 - 20 °C / Inert atmosphere
2: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
3: diethylamine / 20 °C
4: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
Multi-step reaction with 4 steps
1: pyridine / ethyl acetate / 0 - 20 °C / Inert atmosphere
2: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
3: hydrazine hydrate / ethanol; water / 6 h / 44 °C
4: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
oleuropeine
32619-42-4

oleuropeine

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sodium hydroxide; water / 24 h / 20 °C
2: pyridine / ethyl acetate / 0 - 20 °C / Inert atmosphere
3: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
4: diethylamine / 20 °C
5: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
Multi-step reaction with 5 steps
1: sodium hydroxide; water / 24 h / 20 °C
2: pyridine / ethyl acetate / 0 - 20 °C / Inert atmosphere
3: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
4: hydrazine hydrate / ethanol; water / 6 h / 44 °C
5: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
C24H28O14

C24H28O14

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
2: diethylamine / 20 °C
3: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
Multi-step reaction with 3 steps
1: dmap; triethylamine / 0 - 20 °C / Inert atmosphere
2: hydrazine hydrate / ethanol; water / 6 h / 44 °C
3: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
C32H38O16

C32H38O16

Oleocanthal
289030-99-5

Oleocanthal

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol; water / 6 h / 44 °C
2: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: diethylamine / 20 °C
2: β-glucosidase / aq. acetate buffer / 3 h / 37 °C / pH 5 / Enzymatic reaction
View Scheme
Oleocanthal
289030-99-5

Oleocanthal

(3S,4E)-3-(2-hydroxyethyl)-4-hydroxymethylhex-4-enoic acid 2-(4-hydroxyphenyl)ethyl ester
951378-02-2

(3S,4E)-3-(2-hydroxyethyl)-4-hydroxymethylhex-4-enoic acid 2-(4-hydroxyphenyl)ethyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 0℃; for 0.5h;97%
Oleocanthal
289030-99-5

Oleocanthal

(3S,4E)-4-formyl-3-(2-hydroxyethyl)hex-4-enoic acid 2-(4-hydroxyphenyl)ethyl ester

(3S,4E)-4-formyl-3-(2-hydroxyethyl)hex-4-enoic acid 2-(4-hydroxyphenyl)ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 97 percent / NaBH4 / methanol / 0.5 h / 0 °C
2: 52 percent / MnO2 / tetrahydrofuran / 48 h / 23 °C
View Scheme
Oleocanthal
289030-99-5

Oleocanthal

N-methoxylamine hydrochloride
593-56-6

N-methoxylamine hydrochloride

C19H26N2O5
1273095-02-5

C19H26N2O5

Conditions
ConditionsYield
In methanol at 55℃; for 1h;
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