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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Licarbazepine Manufacturer/High quality/Best price/In stock

Cas:29331-92-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE CAS:29331-92-8

Cas:29331-92-8

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-

Cas:29331-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

10,11-Dihydro-10-hydroxy

Cas:29331-92-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

CAS29331-92-8 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

10,11-Dihydro-10-hydroxy carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

10,11-Dihydro-10-Hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

5H-Dibenz[b,f]azepine-5-carboxaMide,10,11-dihydro-10-hydroxy-

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Licarbazepine cas 29331-92-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Licarbazepine cas 29331-92-8

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Other

inquiry

SAGECHEM LIMITED

29331-92-8 Application:intermediate

10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

10,11-Dihydro-10-hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

10,11-Dihydro-10-hydroxy carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Other

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Cas:29331-92-8

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

29331-92-8

Cas:29331-92-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Beijing Top Science biological technology co., LTD

Best service,high quality and reasonable price,COA 1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at m

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zhengzhou Kingorgchem Chemical Technology Co., Ltd.

1. Subsidiary of Institute of Chemistry, Henan Academy of Sciences, national research platform;2. About 30 years’ experience in this field since 1983;3. An experienced R&D team consisting of Doctors and Masters;4. Various types of analytical instrume

National Research Platform ISO 9001 29331-92-8

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

Licarbazepine

Cas:29331-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Reply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

please contact us to confirm the required quantity and quote, we will provide you with COA,NMR,HPLC and other relevant informationAppearance:White solid Storage:Store in a cool place. Keep container tightly closed in a dry and well-ventilated place P

5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Simson Pharma Limited

The system can just identify the products information in first sheet, it is not be permitted to add or edit new sheet by userself.Our products are required in MG to Gram only. · Pharmaceutical Reference Standards· Traceable workin

10,11-Dihydro-10-hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 10,11-Dihydro-10-hydroxy Carbamazepine, CAS:29331-92-8 with the most competitive pric

10,11-Dihydro-10-hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuxi Morality Chemical Co., Ltd

Do best quality products, erect the morality model Application:please email us, thanks

Topbatt Chemical Co., Ltd.

Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes produ

10,11-Dihydro-10-Hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Sumshine Biotech Co., Ltd.

1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

10,11-Dihydro-10-Hydroxy Carbamazepine

Cas:29331-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

oxcarbazepine
28721-07-5

oxcarbazepine

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol; water at 20 - 45℃; for 1.5h;97.3%
With sodium tetrahydroborate In ethanol; water at 45 - 50℃;94%
With sodium tetrahydroborate; water In methanol at 25 - 65℃; for 2.75h;93.8%
carbamazepine 10,11-epoxide
36507-30-9

carbamazepine 10,11-epoxide

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With palladium 10% on activated carbon; ammonium formate In methanol; dichloromethane; water at 20℃; for 1h; Inert atmosphere;93%
With palladium 10% on activated carbon; ammonium formate In methanol; dichloromethane; water at 20℃; for 1h; Inert atmosphere;93%
With hydrogen; triethylamine; palladium on activated charcoal In methanol; water at 50 - 55℃; under 7500.75 - 11251.1 Torr; for 1.66667h;82%
With 5%-palladium/activated carbon; hydrogen; triethylamine In methanol; water under 750.075 Torr; for 2h;63%
10-chloro-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide
791633-38-0

10-chloro-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With water at 20℃; for 48h;90%
With water In 1,3-dioxane; water at 50℃; for 0.666667h;69%
5-Carbamoyl-5H-dibenz[b,f]azepinEN5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine
356760-08-2

5-Carbamoyl-5H-dibenz[b,f]azepinEN5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With sodium perborate; ethanol; water for 0.05h; Product distribution / selectivity; Microwave irradiation;69%
With sodium perborate; water In ethanol for 0.05h; Product distribution / selectivity; Microwave irradiation;69%
With Oxone; sodium hydroxide; water In acetone for 2h; pH=7.5; Product distribution / selectivity; Aqueous phosphate buffer; Heating / reflux;67%
10,11-Dihydrocarbamazepin
3564-73-6

10,11-Dihydrocarbamazepin

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
Streptomyces violascens;
10,11-Dihydrocarbamazepin
3564-73-6

10,11-Dihydrocarbamazepin

A

oxcarbazepine
28721-07-5

oxcarbazepine

B

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

C

10,11-dioxo-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide

10,11-dioxo-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide

D

10-hydroperoxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide

10-hydroperoxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; benzaldehyde; nickel diacetate In acetic acid at 22℃; under 750.06 Torr; for 5h; Product distribution; Further Variations:; Catalysts; Reagents; Solvents; reaction time;A 27 % Chromat.
B 9 % Chromat.
C 1 % Chromat.
D 10 % Chromat.
carbamazepin
298-46-4

carbamazepin

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium permanganate on alumina; sodium carbonate; peroxyacetic acid; acetic acid / dichloromethane / 1.67 h / Reflux
2: ammonium formate; palladium 10% on activated carbon / dichloromethane; methanol; water / 1 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: peracetic acid; sodium carbonate; potassium permanganate; aluminum oxide / dichloromethane / 2 h / 20 °C
2: triethylamine; 5%-palladium/activated carbon; hydrogen / water; methanol / 2 h / 750.08 Torr
View Scheme
Multi-step reaction with 2 steps
1: sodium carbonate; acetic acid; perpropionic acid; / dichloromethane / 2 h / 20 °C / Reflux
2: ammonium formate; palladium 10% on activated carbon / dichloromethane; methanol; water / 1 h / 20 °C / Inert atmosphere
View Scheme
10,11-dihydro-5H-dibenzo[b,f]azepin-10-one
21737-58-6

10,11-dihydro-5H-dibenzo[b,f]azepin-10-one

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dichloromethane / 0 - 5 °C / Inert atmosphere
2: sodium tetrahydroborate / water; ethanol / 45 - 50 °C
View Scheme
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

acetic anhydride
108-24-7

acetic anhydride

Licarbazepine acetate

Licarbazepine acetate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 20℃; for 0.5h;96%
With pyridine Reflux;86%
With triethylamine In dichloromethane Solvent; Reagent/catalyst;4.6 kg
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

Methoxyacetyl chloride
38870-89-2

Methoxyacetyl chloride

licarbazepine methoxyacetate
1296102-92-5

licarbazepine methoxyacetate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 20℃;95%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(1R,2S,5R)-menthyl chloroformate
14602-86-9

(1R,2S,5R)-menthyl chloroformate

carbonic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester 2-isopropyl-5-methyl-cyclohexyl ester

carbonic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester 2-isopropyl-5-methyl-cyclohexyl ester

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;92%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(1S)-(-)-camphanic chloride
39637-74-6

(1S)-(-)-camphanic chloride

4,7,7-trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

4,7,7-trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;90%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

oxcarbazepine
28721-07-5

oxcarbazepine

Conditions
ConditionsYield
With peracetic acid; potassium dichromate; hydrogen In 1,2-dichloro-ethane at 20℃; for 1h;90%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In dichloromethane at 25 - 30℃; for 0.25h;65.5%
Stage #1: 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In dichloromethane at 25 - 30℃; for 0.25h;
Stage #2: With sodium hypochlorite; sodium hydrogencarbonate In dichloromethane; water at 0 - 5℃; for 1h; pH=9.7;
1.3 g
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
6283-74-5

(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate

C23H22N2O9
475674-43-2

C23H22N2O9

Conditions
ConditionsYield
Stage #1: 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide With pyridine; dmap In dichloromethane at 25 - 30℃; for 0.25h;
Stage #2: (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate In dichloromethane at 25 - 30℃; for 2h;
Stage #3: With water In dichloromethane at 15 - 20℃; for 4h;
88.9%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
6283-74-5

(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate

(10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide tartarate

(10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide tartarate

Conditions
ConditionsYield
Stage #1: 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide With pyridine; dmap In dichloromethane at 25 - 30℃; for 0.25h;
Stage #2: (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate In dichloromethane at 25 - 30℃; for 2h; Reagent/catalyst;
88.9%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

licarbazepine ethyl carbonate

licarbazepine ethyl carbonate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;87%
With pyridine In dichloromethane at 20℃; for 1h;72%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

acetyl chloride
75-36-5

acetyl chloride

Licarbazepine acetate

Licarbazepine acetate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;85%
With N-ethyl-N,N-diisopropylamine; dmap In dichloromethane at 20 - 25℃; for 1h;
With pyridine In dichloromethane at 0 - 25℃; for 5h; Large scale;2.65 kg
With pyridine; dmap In dichloromethane at 0 - 20℃; Inert atmosphere;
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

propionic acid anhydride
123-62-6

propionic acid anhydride

(RS)-10,11-dihydro-10-propionyloxy-5H-dibenz[b,f]azepine-5-carboxamide

(RS)-10,11-dihydro-10-propionyloxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With pyridine Reflux;85%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

benzoyl chloride
98-88-4

benzoyl chloride

(RS)-10-benzoyloxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

(RS)-10-benzoyloxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;84%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

butyric acid
107-92-6

butyric acid

(RS)-10-butyroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

(RS)-10-butyroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;80%
nicotinic acid
59-67-6

nicotinic acid

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

nicotinic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

nicotinic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;76%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

propionic acid
802294-64-0

propionic acid

(RS)-10,11-dihydro-10-propionyloxy-5H-dibenz[b,f]azepine-5-carboxamide

(RS)-10,11-dihydro-10-propionyloxy-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;75%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

L-menthoxyacetyl chloride
15356-62-4

L-menthoxyacetyl chloride

(2-isopropyl-5-methyl-cyclohexyloxy)-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

(2-isopropyl-5-methyl-cyclohexyloxy)-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;71%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

t-Boc-L-valine
13734-41-3

t-Boc-L-valine

2-tert-butoxycarbonylamino-3-methyl-butyric acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

2-tert-butoxycarbonylamino-3-methyl-butyric acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;66%
4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(4-methoxy-phenyl)-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

(4-methoxy-phenyl)-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;60%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

valproic acid
99-66-1

valproic acid

10-[(2-propyl)pentanoyloxy]-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

10-[(2-propyl)pentanoyloxy]-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;59%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

O-acetylsalicyloyl chloride
5538-51-2

O-acetylsalicyloyl chloride

10-(2-acetoxybenzoyloxy)-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

10-(2-acetoxybenzoyloxy)-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;56%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

chloroacetic acid
79-11-8

chloroacetic acid

chloro-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

chloro-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;55%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(R,S)-2-chloropropionic acid
598-78-7

(R,S)-2-chloropropionic acid

2-chloro-propionic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

2-chloro-propionic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;55%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

4-nitrobenzeneacetic acid
104-03-0

4-nitrobenzeneacetic acid

10-(4-nitrophenyl)acetoxy-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

10-(4-nitrophenyl)acetoxy-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;52%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

(S)-2-chloro-2-oxo-1-phenylethyl acetate
51019-44-4

(S)-2-chloro-2-oxo-1-phenylethyl acetate

acetoxy-phenyl-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

acetoxy-phenyl-acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;52%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

2-ethylvaleric acid
20225-24-5

2-ethylvaleric acid

2-ethyl-pentanoic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

2-ethyl-pentanoic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;50%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

pivaloyl chloride
3282-30-2

pivaloyl chloride

2,2-dimethyl-propionic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

2,2-dimethyl-propionic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 1h; Ambient temperature;50%
10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
29331-92-8

10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

benzoic acid anhydride
93-97-0

benzoic acid anhydride

(RS)-10-benzoyloxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

(RS)-10-benzoyloxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

Conditions
ConditionsYield
With pyridine Reflux;50%

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