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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

Jinan Finer Chemical Co., Ltd

Product description: Product name D7-Amino-3-[(2-methyl-1,3,4-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid CAS number 30246-33-4 Assay ≥99% Appearance White powder Capacity 200

7-Amino-3-[(2-methyl-1,3,4-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid

Cas:30246-33-4

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)-thiomethyl]-cephalosporanic acid

Cas:30246-33-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Cefazedone Intermediate CAS No: 30246-33-4 7-Tda

Cas:30246-33-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com

TIANFU-CHEM - 7-AMINO-3-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)THIOMETHYL]CEPHALOSPHORANIC ACID

Cas:30246-33-4

Min.Order:1 Gram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

99% PureCAS 30246-33-4 with fast shipping

Cas:30246-33-4

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply 7-TDA CAS 30246-33-4

Cas:30246-33-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid CAS:30246-33-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of che

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid CAS:30246-33-4

Cas:30246-33-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

best price,best quality and fast delivery assurance available in sample product and customization with years of export experience along with excellent quality, advanced services and competitive prices the quality of products conform u

Cefazolin EP Impurity A CAS NO.30246-33-4

Cas:30246-33-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 30246-33-4 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid

Cas:30246-33-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

7-AMINO-3-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)THIOMETHYL]CEPHALOSPHORANIC ACID

Cas:30246-33-4

Min.Order:1 Kilogram

FOB Price: $60.0 / 80.0

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

PARENT NUCLEUS OF CEFAZEDONE (7-TDA)

Cas:30246-33-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

7-AMINO-3-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)THIOMETHYL]CEPHALOSPHORANIC ACID

Cas:30246-33-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid

Cas:30246-33-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl]cephalosphoranic acid

Cas:30246-33-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

cas:30246-33-4

Cas:30246-33-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

High quality 7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]Cephalosphoranic Acid supplier in

Cas:30246-33-4

Min.Order:1 Kilogram

FOB Price: $120.0 / 150.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranicacid CAS No.: 30246-33-4 Molecule Formula:C11H12N4O3S3 Molecule Weight:344.43 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufactur

Lower Price 7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranicacid on stock

Cas:30246-33-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Cefazolin Impurity 7(Cefazolin EP Impurity A)

Cas:30246-33-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]CephalosphoranicAcid

Cas:30246-33-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Product name: 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid CAS No.: 30246-33-4 Chemical name: 7-AMINO-3-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)THIOMETHYL]CEPHALOSPHORANIC ACID;TDA;(7r)-7-amino-3-[(5-methyl-1,3

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid

Cas:30246-33-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid Synonyms: (7r)-7-amino-3[(5-methyl-1,3,4-thiadiazole-2-yl)thiomethyl]-3-cephem-4-carboxylic acid;7-Amino-3-([5-methyl-1,3,4-thiadiazol-2-yl] thiomethy

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of service

7-TDA

Cas:30246-33-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

7-AMINO-3-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)THIOMETHYL]CEPHALOSPHORANIC ACID

Cas:30246-33-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

7-TDA

Cas:30246-33-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-mercapto-5-methyl-1,3,4-thiadiazole
29490-19-5

2-mercapto-5-methyl-1,3,4-thiadiazole

3-acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid

3-acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

Conditions
ConditionsYield
With boric acid; triethylamine In water96%
In water; acetone
In water; acetone
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0 ]oct-2-ene-2-carboxylic acid sodium salt
3855-09-2

3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0 ]oct-2-ene-2-carboxylic acid sodium salt

2-mercapto-5-methyl-1,3,4-thiadiazole
29490-19-5

2-mercapto-5-methyl-1,3,4-thiadiazole

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water
With sodium hydrogencarbonate In water
With sodium hydrogencarbonate In water
With sodium hydrogencarbonate In water
pyrrolidine
123-75-1

pyrrolidine

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-2-(pyrrolidine-1-carbonyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-8-one

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-2-(pyrrolidine-1-carbonyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-8-one

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.0333333h; microwave irradiation;93%
2-amino-5-(3-pyridyl)-1,3,4-thiadiazole
68787-52-0

2-amino-5-(3-pyridyl)-1,3,4-thiadiazole

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-pyridin-3-yl-[1,3,4]thiadiazol-2-yl)-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-pyridin-3-yl-[1,3,4]thiadiazol-2-yl)-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.0166667h; microwave irradiation;92%
2-amino-5-undecyl-1,3,4-thiadiazole
100539-95-5

2-amino-5-undecyl-1,3,4-thiadiazole

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-undecyl-[1,3,4]thiadiazol-2-yl)-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-undecyl-[1,3,4]thiadiazol-2-yl)-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.0333333h; microwave irradiation;90%
piperidine
110-89-4

piperidine

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-2-(piperidine-1-carbonyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-8-one

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-2-(piperidine-1-carbonyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-8-one

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.025h; microwave irradiation;89%
2-amino-5-phenyl-1,3,4-thiadiazole
2002-03-1

2-amino-5-phenyl-1,3,4-thiadiazole

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-phenyl-[1,3,4]thiadiazol-2-yl)-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-phenyl-[1,3,4]thiadiazol-2-yl)-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.0166667h; microwave irradiation;87%
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

2-amino-5-(4-chlorophenyl)-1,3,4-thiadiazole
28004-62-8

2-amino-5-(4-chlorophenyl)-1,3,4-thiadiazole

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid [5-(4-chloro-phenyl)-[1,3,4]thiadiazol-2-yl]-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid [5-(4-chloro-phenyl)-[1,3,4]thiadiazol-2-yl]-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.025h; microwave irradiation;86%
5-methyl-1,3,4-thiadiazol-2-amine
108-33-8

5-methyl-1,3,4-thiadiazol-2-amine

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-methyl-[1,3,4]thiadiazol-2-yl)-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-methyl-[1,3,4]thiadiazol-2-yl)-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.025h; microwave irradiation;85%
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

5-nonyl-[1,3,4]thiadiazol-2-ylamine
113836-51-4

5-nonyl-[1,3,4]thiadiazol-2-ylamine

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-nonyl-[1,3,4]thiadiazol-2-yl)-amide

7-amino-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-nonyl-[1,3,4]thiadiazol-2-yl)-amide

Conditions
ConditionsYield
With aluminum oxide at 120℃; for 0.025h; microwave irradiation;83%
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

A

7-amino-3-methylenecepham-4-carboxylic acid
36996-01-7, 51795-31-4

7-amino-3-methylenecepham-4-carboxylic acid

B

7-aminodesacetoxycephalosporanic acid
26395-99-3

7-aminodesacetoxycephalosporanic acid

Conditions
ConditionsYield
With N,N-Bis(trimethylsilyl)urea; ammonium chloride; zinc In N,N-dimethyl-formamide 1.) 25 deg C, 13 min, 2.) 5 deg C, 18 min, 3.) 5 deg C, 30 min;A 66.5%
B 3.0 % Chromat.
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-amino-3-hydroxycepham-4-carboxylic acid
68403-70-3, 115889-60-6

7-amino-3-hydroxycepham-4-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 66.5 percent / bis(trimethylsilyl)urea (BSU), NH4Cl, zinc dust / dimethylformamide / 1.) 25 deg C, 13 min, 2.) 5 deg C, 18 min, 3.) 5 deg C, 30 min
2: 1.) MsOH, ozone, 2.) NaBH4, NaOH / 1.) MeOH, -75 deg C, 2.) MeOH/H2O, 0 - 10 deg C
View Scheme
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

3-methylene-7-phenylacetamidocepham-4-carboxylic acid 1-sulfoxide
115824-01-6, 121055-15-0

3-methylene-7-phenylacetamidocepham-4-carboxylic acid 1-sulfoxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 66.5 percent / bis(trimethylsilyl)urea (BSU), NH4Cl, zinc dust / dimethylformamide / 1.) 25 deg C, 13 min, 2.) 5 deg C, 18 min, 3.) 5 deg C, 30 min
2: 1.) ozone, MsOH, 2.) NaBH4 / 1.) MeOH, -40 deg C, 2.) MeOH/H2O, 3.) pH 6.5 - 7.5
View Scheme
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

3-hydroxy-7-phenylacetamido-cepham-4-carboxylic acid
90305-32-1, 115889-59-3

3-hydroxy-7-phenylacetamido-cepham-4-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 66.5 percent / bis(trimethylsilyl)urea (BSU), NH4Cl, zinc dust / dimethylformamide / 1.) 25 deg C, 13 min, 2.) 5 deg C, 18 min, 3.) 5 deg C, 30 min
2: 1.) ozone, MsOH, 2.) NaBH4 / 1.) MeOH, -40 deg C, 2.) MeOH/H2O, 3.) pH 6.5 - 7.5
View Scheme
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

7-[[2-carboethoxy-2-(1-pyrryl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

7-[[2-carboethoxy-2-(1-pyrryl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

7-aminocephalosporanic acid
108260-00-0

7-aminocephalosporanic acid

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

isobutene
115-11-7

isobutene

3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester
6187-87-7, 102253-55-4

3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sulfuric acid; sodium hydrogencarbonate In 1,4-dioxane; ethyl acetate; 7-aminodesacetoxycephalosporanic acid
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid
30246-33-4

7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

A

7-amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid t-butyl ester
54895-35-1

7-amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid t-butyl ester

B

3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester
6187-87-7, 102253-55-4

3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
In 7-aminodesacetoxycephalosporanic acid
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