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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,5-Dichloroanisole supplier in China

Cas:33719-74-3

Min.Order:0 Metric Ton

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Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract 3,5-Dichloroanisole HACCP manufacturer

Cas:33719-74-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3,5-dichloroanisole

Cas:33719-74-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 33719-74-3 with best quality

Cas:33719-74-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzene,1,3-dichloro-5-methoxy- 33719-74-3

Cas:33719-74-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3,5-Dichloroanisole CAS:33719-74-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

3,5-Dichloroanisole CAS:33719-74-3

Cas:33719-74-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzene,1,3-dichloro-5-methoxy-

Cas:33719-74-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzene,1,3-dichloro-5-methoxy-

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

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Type:Manufacturers

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

1,3-Dichloro-5-methoxybenzene

Cas:33719-74-3

Min.Order:1 Gram

FOB Price: $61.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,5-dichloroanisole

Cas:33719-74-3

Min.Order:0 Metric Ton

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Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzene,1,3-dichloro-5-methoxy-

Cas:33719-74-3

Min.Order:0

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Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Trading Company

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,5-Dichloroanisole cas no. 33719-74-3 98%

Cas:33719-74-3

Min.Order:0

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

3,5-dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3,5-dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Other

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Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

Best price 3,5-Dichloroanisole 33719-74-3

Cas:33719-74-3

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 3,5-Dichloroanisole D67210 1g

Cas:33719-74-3

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Manufacturers

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Benzene,1,3-dichloro-5-methoxy-

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Manufacturers

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzene,1,3-dichloro-5-methoxy-

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

3,5-Dichloroanisole CAS No.33719-74-3

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Trading Company

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DB BIOTECH CO., LTD

best seller Application:API

3,5-Dichloroanisole

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

3,5-DICHLOROANISOLEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3,5-DICHLOROANISOLE

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Other

inquiry

Changzhou Ansciep Chemical Co.,Ltd.

reagent grade ex stockAppearance:white or off-white crystalline powder Storage:Keep away of light,cool place Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:by Fedex, ship or plane

1,3-dichloro-5-methoxybenzene

Cas:33719-74-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

dimethyl sulfate
77-78-1

dimethyl sulfate

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
With potassium carbonate In acetone for 3h;100%
With potassium carbonate In acetone for 3h; Ambient temperature;100%
With sodium hydroxide
3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 90℃; Inert atmosphere;100%
1,3,5-trichlorobenzene
108-70-3

1,3,5-trichlorobenzene

sodium methylate
124-41-4

sodium methylate

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
In dimethyl sulfoxide at 80 - 90℃; Concentration; Reagent/catalyst; Solvent; Temperature; Time;98%
In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 1h;78%
In methanol; dimethyl sulfoxide at 50.1℃; Rate constant;
With methanol at 180℃;
methanol
67-56-1

methanol

1,3,5-trichlorobenzene
108-70-3

1,3,5-trichlorobenzene

sodium methylate
124-41-4

sodium methylate

A

3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

B

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
at 180℃; im Rohr;
at 175℃; Kinetics; im Rohr;
3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

methyl iodide
74-88-4

methyl iodide

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl acetamide at 25℃; Rate constant;
3,5-dichlorophenolate
65800-69-3

3,5-dichlorophenolate

S-methyldibenzothiophenium tetrafluoroborate
29829-22-9

S-methyldibenzothiophenium tetrafluoroborate

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
In methanol at 30℃; for 3h;
3,5-Dichloroaniline
626-43-7

3,5-Dichloroaniline

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Diazotization.Verkochen mit H2SO4
2: NaOH-solution
View Scheme
2-(3-chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
929626-16-4

2-(3-chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Conditions
ConditionsYield
With copper dichloride In methanol at 90℃;193 mg
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

3,4,5-trichloroanisole
54135-82-9

3,4,5-trichloroanisole

Conditions
ConditionsYield
With trichloroisocyanuric acid In N,N-dimethyl-formamide for 1h;87%
With 1,3,5-trichloro-2,4,6-triazine In N,N-dimethyl-formamide for 1h; Ambient temperature;87%
With chlorine
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

2,4-dichlorobenzoyl chloride
89-75-8

2,4-dichlorobenzoyl chloride

(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methanone
934562-64-8

(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methanone

Conditions
ConditionsYield
With aluminium trichloride In nitrobenzene at -78 - 20℃; for 25h; Friedel-Crafts reaction;85%
With aluminum (III) chloride In nitrobenzene at -78 - 20℃; for 25h;85%
Stage #1: 3,5-dichloroanisole; 2,4-dichlorobenzoyl chloride With aluminum (III) chloride In nitromethane at -78 - 20℃; for 25h; Friedel Crafts Acylation;
Stage #2: With sodium hydroxide In diethyl ether; nitromethane at 0℃; Product distribution / selectivity; Friedel Crafts Acylation;
80%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

3-chloro-5-methoxyphenol
65262-96-6

3-chloro-5-methoxyphenol

Conditions
ConditionsYield
With copper acetylacetonate; N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water In water; dimethyl sulfoxide at 130℃; for 24h; Schlenk technique; Inert atmosphere;82%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

A

1-methoxy-3,5-diamino-benzene
100-96-9

1-methoxy-3,5-diamino-benzene

B

3-chloro-5-methoxyaniline
10272-06-7

3-chloro-5-methoxyaniline

Conditions
ConditionsYield
With ammonium hydroxide; potassium phosphate; copper(l) iodide; N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide In water; dimethyl sulfoxide at 110℃; for 24h; Concentration; Inert atmosphere; Sealed tube;A 10%
B 81%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

2,4,6-trichlorobenzoyl chloride
4136-95-2

2,4,6-trichlorobenzoyl chloride

(2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methanone
1380572-64-4

(2,6-dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl)methanone

Conditions
ConditionsYield
With aluminum (III) chloride In nitrobenzene at 0 - 20℃; Friedel-Crafts reaction;80%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Propionamid
79-05-0

Propionamid

N-(3-chloro-5-methoxyphenyl)propionamide

N-(3-chloro-5-methoxyphenyl)propionamide

Conditions
ConditionsYield
With copper(I) oxide; potassium phosphate; N1,N2-bis(thiophen-2-ylmethyl)oxalamide In tert-butyl alcohol at 130℃; for 24h; Schlenk technique;78%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

1,3-dichloro-2-iodo-5-methoxybenzene
98273-17-7

1,3-dichloro-2-iodo-5-methoxybenzene

Conditions
ConditionsYield
With iodine; silver sulfate In acetonitrile at 20℃; for 72h; Inert atmosphere;77%
Multi-step reaction with 3 steps
1: HNO3; H2SO4 / CH2Cl2 / 18 h / 20 °C
2: 7 percent / Na2S2O4 / aq. ethanol / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: sulfuric acid; nitric acid / dichloromethane / 18 h
1.2: 14 h / Heating
2.1: sulfuric acid; potassium iodide; sodium nitrite / water / 18 h / 0 °C / Heating
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid; nitric acid / dichloromethane / 18 h
2: sodium dithionite / ethanol; water / 14 h / Heating
3: sulfuric acid; potassium iodide; sodium nitrite / water / 18 h / 0 °C / Heating
View Scheme
With iodine; silver sulfate In acetonitrile at 20℃; for 42h; regioselective reaction;65 %Chromat.
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

2,6-Dichlorobenzoyl chloride
4659-45-4

2,6-Dichlorobenzoyl chloride

(2,4-dichloro-6-hydroxyphenyl)(2,6-dichlorophenyl)methanone
34786-96-4

(2,4-dichloro-6-hydroxyphenyl)(2,6-dichlorophenyl)methanone

Conditions
ConditionsYield
With aluminum (III) chloride at 0 - 110℃; for 15h; Inert atmosphere;72%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

Conditions
ConditionsYield
With boron triiodide-N,N-diethylaniline In benzene for 4h; Ambient temperature;67%
With hydrogen bromide In water Reflux;
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

(2-(4-bromophenyl)ethynyl)triisopropylsilane
271242-20-7

(2-(4-bromophenyl)ethynyl)triisopropylsilane

2'-iodo-5'-methoxy-4,4''-bis[2-(triisopropylsilyl)ethynyl]-1,1':3',1''-terphenyl

2'-iodo-5'-methoxy-4,4''-bis[2-(triisopropylsilyl)ethynyl]-1,1':3',1''-terphenyl

Conditions
ConditionsYield
Stage #1: 3,5-dichloroanisole With [bis-(trifluoroacetoxy)iodo]benzene; iodine In dichloromethane at 20℃; for 2.5h;
Stage #2: (2-(4-bromophenyl)ethynyl)triisopropylsilane With tert.-butyl lithium In diethyl ether; pentane at 10 - 20℃; for 15h;
Stage #3: With iodine In diethyl ether; pentane at 0℃; for 1h;
66%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

Potassium; 3,5-dichloro-phenolate

Potassium; 3,5-dichloro-phenolate

Conditions
ConditionsYield
With Triton X-114; potassium thioacyanate at 180℃; for 6h;65%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

A

1,5-dichloro-2-iodo-3-methoxybenzene
1271523-34-2

1,5-dichloro-2-iodo-3-methoxybenzene

B

1,3-dichloro-2-iodo-5-methoxybenzene
98273-17-7

1,3-dichloro-2-iodo-5-methoxybenzene

Conditions
ConditionsYield
With [bis-(trifluoroacetoxy)iodo]benzene; iodine In dichloromethane at 20℃; for 2.5h; Overall yield = 85 %; Overall yield = 3.20 g;A 21%
B 64%
With N-iodo-succinimide; toluene-4-sulfonic acid In acetonitrile for 18h; regioselective reaction;A 14 %Chromat.
B 68 %Chromat.
piperidine
110-89-4

piperidine

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

1,1′-(5-methoxy-1,3-phenylene)dipiperidine

1,1′-(5-methoxy-1,3-phenylene)dipiperidine

Conditions
ConditionsYield
With potassium tert-butylate In toluene at 155℃; for 24h; Autoclave;63%
furan
110-00-9

furan

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

7-chloro-5-methoxy-1,4-dihydro-1,4-epoxidonaphthalene

7-chloro-5-methoxy-1,4-dihydro-1,4-epoxidonaphthalene

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 0℃; for 3h;60%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

2,4,6-trichlorobenzoyl chloride
4136-95-2

2,4,6-trichlorobenzoyl chloride

(2,4-dichloro-6-hydroxyphenyl)(2,4,6-trichlorophenyl)methanone

(2,4-dichloro-6-hydroxyphenyl)(2,4,6-trichlorophenyl)methanone

Conditions
ConditionsYield
With aluminum (III) chloride at 0 - 110℃; for 15h; Inert atmosphere;58.6%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

ethylene dibromide
106-93-4

ethylene dibromide

3-methoxy-5-chlorobenzaldehyde
164650-68-4

3-methoxy-5-chlorobenzaldehyde

Conditions
ConditionsYield
Stage #1: 3,5-dichloroanisole; ethylene dibromide With magnesium In tetrahydrofuran for 3h; Heating / reflux;
Stage #2: With N,N-dimethyl-formamide In tetrahydrofuran at 0℃;
54%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

3-methoxy-5-chlorobenzaldehyde
164650-68-4

3-methoxy-5-chlorobenzaldehyde

Conditions
ConditionsYield
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran at 0 - 25℃; for 3h; Heating / reflux;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran
Stage #3: With hydrogenchloride; water In tetrahydrofuran
54%
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran for 3h; Heating / reflux;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at 0℃;
54%
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran for 3h; Heating / reflux;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at 0℃;
54%
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran for 3h; Heating / reflux;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at 0℃;
54%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

sodium methylate
124-41-4

sodium methylate

A

3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

B

3-chloro-5-methoxyphenol
65262-96-6

3-chloro-5-methoxyphenol

C

1-chloro-3,5-dimethoxybenzene
7051-16-3

1-chloro-3,5-dimethoxybenzene

Conditions
ConditionsYield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃;A 51%
B 7%
C 40%
In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 1h;A 51%
B 7%
C 40%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

A

3,5-dichlorophenol
591-35-5

3,5-dichlorophenol

B

3-chloro-5-methoxyphenol
65262-96-6

3-chloro-5-methoxyphenol

C

1-chloro-3,5-dimethoxybenzene
7051-16-3

1-chloro-3,5-dimethoxybenzene

Conditions
ConditionsYield
With sodium methylate In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 1h;A 51%
B 7%
C 40%
carbon dioxide
124-38-9

carbon dioxide

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

3-chloro-5-methoxy-benzoic acid
82477-67-6

3-chloro-5-methoxy-benzoic acid

Conditions
ConditionsYield
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran for 2h; Heating / reflux;
Stage #2: carbon dioxide In tetrahydrofuran
41%
With hydrogenchloride; magnesium Yield given. Multistep reaction;
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

3-chloro-5-methoxy-benzoic acid
82477-67-6

3-chloro-5-methoxy-benzoic acid

Conditions
ConditionsYield
Stage #1: 3,5-dichloroanisole With magnesium; ethylene dibromide In tetrahydrofuran for 2h; Heating / reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran; water
41%
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

acetyl chloride
75-36-5

acetyl chloride

1-(2,6-dichloro-4-methoxyphenyl)ethanone
157487-30-4

1-(2,6-dichloro-4-methoxyphenyl)ethanone

Conditions
ConditionsYield
Stage #1: acetyl chloride With aluminum (III) chloride In dichloromethane at 0℃; for 0.5h;
Stage #2: 3,5-dichloroanisole In dichloromethane at 20℃; for 2h;
40%
formaldehyd
50-00-0

formaldehyd

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

(2,6-dichloro-4-methoxy-phenyl)-methanol
86111-47-9

(2,6-dichloro-4-methoxy-phenyl)-methanol

Conditions
ConditionsYield
Stage #1: formaldehyd; 3,5-dichloroanisole With hydrogenchloride; sulfuric acid In water at 60℃;
Stage #2: With sodium hydroxide In 1,4-dioxane; water for 3h; Heating;
30%
With hydrogenchloride; sulfuric acid In water at 60℃;30%
Stage #1: formaldehyd; 3,5-dichloroanisole With hydrogenchloride; sulfuric acid In water at 100℃; for 8h;
Stage #2: With water; sodium hydroxide In 1,4-dioxane at 100℃; for 3h;
4.67 g
Dichloromethyl methyl ether
4885-02-3

Dichloromethyl methyl ether

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

2,6-dichloro-4-methoxy-benzaldehyde
82772-93-8

2,6-dichloro-4-methoxy-benzaldehyde

Conditions
ConditionsYield
With tin(IV) chloride In dichloromethane 1.) 0 deg C, 30 min, 2.) RT, 3 h;28%
formaldehyd
50-00-0

formaldehyd

3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

A

2,4-dichloro-6-methoxybenzyl alcohol
911718-18-8

2,4-dichloro-6-methoxybenzyl alcohol

B

(2,6-dichloro-4-methoxy-phenyl)-methanol
86111-47-9

(2,6-dichloro-4-methoxy-phenyl)-methanol

Conditions
ConditionsYield
With hydrogenchloride; sulfuric acid In water at 60℃; for 7h; Inert atmosphere;A 15%
B 25%
Stage #1: formaldehyd; 3,5-dichloroanisole With hydrogenchloride; sulfuric acid In water at 70℃; for 7h; Inert atmosphere;
Stage #2: With sodium hydroxide In 1,4-dioxane; water for 7h; Reflux; Inert atmosphere;
A 3.74 g
B 7.9 g
3,5-dichloroanisole
33719-74-3

3,5-dichloroanisole

A

4-bromo-3,5-dichloroanisole

4-bromo-3,5-dichloroanisole

B

C7H5BrCl2O
73931-43-8

C7H5BrCl2O

Conditions
ConditionsYield
With hydrogenchloride; N-Bromosuccinimide In water; acetone at 20℃; for 0.5h;A 25%
B n/a
With hydrogenchloride; N-Bromosuccinimide; water In acetone at 20℃; for 0.0833333h; Inert atmosphere;

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