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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Methyl 2-chloromethylbenzoate Manufacturer/High quality/Best price/In stock

Cas:34040-62-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-(Chloromethyl)-Benzoic Acid Methyl Ester supplier in China

Cas:34040-62-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

huge stock TC herbicide Methyl 2-chloromethylbenzoate 34040-62-5 GLP Manufacturer

Cas:34040-62-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(Chloromethyl)-benzoic acid methyl ester

Cas:34040-62-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 34040-62-5 with competitive price

Cas:34040-62-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,2-(chloromethyl)-, methyl ester 34040-62-5

Cas:34040-62-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Methyl 2-chloromethylbenzoate CAS:34040-62-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

Methyl 2-chloromethylbenzoate CAS:34040-62-5

Cas:34040-62-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,2-(chloromethyl)-, methyl ester

Cas:34040-62-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-(chloromethyl)-benzoic acid methyl ester

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoic acid,2-(chloromethyl)-, methyl ester

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-(Chloromethyl)-Benzoic Acid Methyl Ester

Cas:34040-62-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:1 Kilogram

FOB Price: $25.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

Methyl 2-chloromethylbenzoateCAS NO.: 34040-62-5

Cas:34040-62-5

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl o-chloromethyl benzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

Methyl 2-chloromethylbenzoate Manufacturer/High quality/Best price/In stock CAS NO.34040-62-5

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Methyl 2-(chloromethyl)benzoate 25g

Cas:34040-62-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

2-(Chloromethyl)-Benzoic Acid Methyl Ester

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Nanjing Fred Technology Co.,Ltd.

Fredchem focus on CRO/CMO business and its own R&D of API/Intermediates Package:Grams, Kilograms Application:Pharmaceutical field Transportation:According to customer request Port:Shanghai

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzoic acid,2-(chloromethyl)-, methyl ester

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Methyl 2-chloromethylbenzoate cas 34040-62-5Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Methyl 2-chloromethylbenzoate cas 34040-62-5

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

methyl 2-(chloromethyl)benzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Methyl o-chloromethyl benzoate 34040-62-5

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Methyl o-chloromethyl benzoate 34040-62-5

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Methyl 2-chloromethylbenzoate

Cas:34040-62-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

methanol
67-56-1

methanol

2-benzofuran-1(3H)-one
87-41-2

2-benzofuran-1(3H)-one

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 2-benzofuran-1(3H)-one With boron trifluoride diethyl etherate; N-benzyl-N,N,N-triethylammonium chloride In xylene at 100℃;
Stage #2: With thionyl chloride In xylene at 100 - 132℃; for 3h;
Stage #3: methanol at 50 - 60℃; for 2h;
100%
Stage #1: 2-benzofuran-1(3H)-one With dichlorotriphenyl-λ4-phosphane at 180℃; for 2h;
Stage #2: methanol With pyridine for 1h;
With pyridine; dichlorotriphenylphosphorane at 180℃;
methanol
67-56-1

methanol

2-(chloromethyl)benzoic acid
85888-81-9

2-(chloromethyl)benzoic acid

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid at 80℃; for 6h; Temperature;96.5%
2-Chloromethylbenzoyl chloride
42908-86-1

2-Chloromethylbenzoyl chloride

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
In methanol94%
With triethylamine In methanol; dichloromethane89%
2-Methyl-benzoic acid methyl ester
89-71-4

2-Methyl-benzoic acid methyl ester

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
With N-hydroxyphthalimide; carbon tetrabromide; trichloroisocyanuric acid; copper(II) acetate monohydrate In dichloromethane at 25℃; for 24h;61%
With N-hydroxyphthalimide; carbon tetrabromide; trichloroisocyanuric acid; copper(II) acetate monohydrate In dichloromethane at 25℃; for 20h;49%
methyl 3-<2-(methoxycarbonyl)benzyloxy>phenylacetate
93273-66-6

methyl 3-<2-(methoxycarbonyl)benzyloxy>phenylacetate

A

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

B

3-hydroxy-benzeneacetic acid, methyl ester
42058-59-3

3-hydroxy-benzeneacetic acid, methyl ester

C

methyl 3-hydroxy-4-<2-(methoxycarbonyl)benzyl>phenylacetate
93273-67-7

methyl 3-hydroxy-4-<2-(methoxycarbonyl)benzyl>phenylacetate

Conditions
ConditionsYield
With aluminium trichloride In 1,2-dichloro-ethane for 0.666667h; Ambient temperature;A 30.9%
B 55.2%
C 28.7%
methanol
67-56-1

methanol

2-Chloromethylbenzoyl chloride
42908-86-1

2-Chloromethylbenzoyl chloride

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
With pyridine for 18h; Yield given;
for 3h; Heating;1000 mg
Stage #1: methanol; 2-Chloromethylbenzoyl chloride at 50 - 60℃; for 2h;
Stage #2: With potassium carbonate In water; toluene for 0.5h;
3-(2-carboxybenzyloxy)phenylacetic acid
55690-19-2

3-(2-carboxybenzyloxy)phenylacetic acid

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95.3 percent / conc. H2SO4 / 22 h / Heating
2: 30.9 percent / aluminium chloride / 1,2-dichloro-ethane / 0.67 h / Ambient temperature
View Scheme
2-benzofuran-1(3H)-one
87-41-2

2-benzofuran-1(3H)-one

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride; N-benzyl-N,N,N-triethylammonium chloride
2: methanol
View Scheme
ortho-methylbenzoic acid
118-90-1

ortho-methylbenzoic acid

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2,2'-azobis(isobutyronitrile); thionyl chloride / 1,2-dichloro-ethane / 4 h / 60 °C
2: sulfuric acid / 6 h / 80 °C
View Scheme
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid 1,1-dimethylethyl ester
161468-45-7

2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid 1,1-dimethylethyl ester

tert-butyl 3-(2-(methoxycarbonyl)benzyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-carboxylate

tert-butyl 3-(2-(methoxycarbonyl)benzyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-carboxylate

Conditions
ConditionsYield
With caesium carbonate In dimethyl sulfoxide at 80℃; for 5h;100%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

cyclohexylamine
108-91-8

cyclohexylamine

2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one
3823-13-0

2-cyclohexyl-2,3-dihydro-1H-isoindol-1-one

Conditions
ConditionsYield
In neat (no solvent) at 140℃; for 2h;98%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

aniline
62-53-3

aniline

N-phenylphthalimidine
5388-42-1

N-phenylphthalimidine

Conditions
ConditionsYield
In neat (no solvent) at 140℃; for 2h;98%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

Methyl 4-hydroxyphenylacetate
14199-15-6

Methyl 4-hydroxyphenylacetate

4-(2-methoxycarbonylbenzyloxy)phenyl acetic acid
1009378-92-0

4-(2-methoxycarbonylbenzyloxy)phenyl acetic acid

Conditions
ConditionsYield
With potassium carbonate In ethanol for 24h; Reagent/catalyst; Reflux;96.9%
With potassium carbonate In ISOPROPYLAMIDE at 90℃; for 8h;
With potassium carbonate In ISOPROPYLAMIDE at 90℃; for 8h;
2-mercapto-4-methylbenzonitrile
613263-26-6

2-mercapto-4-methylbenzonitrile

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

methyl 2-{[(2-cyano-5-methylphenyl)thio]methyl}benzoate

methyl 2-{[(2-cyano-5-methylphenyl)thio]methyl}benzoate

Conditions
ConditionsYield
With triethylamine In chloroform for 0.666667h; Reflux;92%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

4-chloro-2-mercaptobenzonitrile
1339650-77-9

4-chloro-2-mercaptobenzonitrile

methyl 2-{[(5-chloro-2-cyanophenyl)thio]methyl}benzoate

methyl 2-{[(5-chloro-2-cyanophenyl)thio]methyl}benzoate

Conditions
ConditionsYield
With triethylamine In chloroform for 0.666667h; Reflux;86%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

4,6-diphenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile
58327-74-5

4,6-diphenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4,6-diphenylpyridine

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4,6-diphenylpyridine

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;86%
methanol
67-56-1

methanol

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

methyl 2-(methoxymethyl)benzoate
942-57-4

methyl 2-(methoxymethyl)benzoate

Conditions
ConditionsYield
With sodium hydride for 4h; Heating;85%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2-cyanothiophenol
34761-11-0

2-cyanothiophenol

methyl 2-{[(2-cyanophenyl)thio]methyl}benzoate

methyl 2-{[(2-cyanophenyl)thio]methyl}benzoate

Conditions
ConditionsYield
With triethylamine In chloroform for 0.666667h; Reflux;84%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

6-(4-bromophenyl)-3-cyano-4-phenylpyridine-2(1H)-thione

6-(4-bromophenyl)-3-cyano-4-phenylpyridine-2(1H)-thione

6-(4-bromophenyl)-3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4-phenylpyridine

6-(4-bromophenyl)-3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4-phenylpyridine

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;84%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2-(Chlorosulfonylmethyl)benzoic acid methyl ester
103342-27-4

2-(Chlorosulfonylmethyl)benzoic acid methyl ester

Conditions
ConditionsYield
With Sodium thiosulfate pentahydrate; chlorine; acetic acid In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water83%
Multi-step reaction with 2 steps
1: sodium thiosulfate / water / 3 h / 70 °C
2: water; chlorine / 1,2-dichloro-benzene / 5 h / 10 - 30 °C
View Scheme
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

o-(2-ethoxycarbonyl)phenylmethanesulfonyl chloride
221631-54-5

o-(2-ethoxycarbonyl)phenylmethanesulfonyl chloride

Conditions
ConditionsYield
With Sodium thiosulfate pentahydrate81%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

methyl 2-(chloromethyl)-5-nitrobenzoate
90537-42-1

methyl 2-(chloromethyl)-5-nitrobenzoate

Conditions
ConditionsYield
With sulfuric acid; potassium nitrate at 0 - 20℃; for 4h;80%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

1,2,5,6,7,8-hexahydro-2-thioxoquinoline-3-carbonitrile
112629-69-3

1,2,5,6,7,8-hexahydro-2-thioxoquinoline-3-carbonitrile

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-5,6,7,8-tetrahydroquinoline

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-5,6,7,8-tetrahydroquinoline

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;78%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2-Fluorobenzaldehyde
446-52-6

2-Fluorobenzaldehyde

3-(2-fluorophenyl)-3,4-dihydroisocoumarin
95217-42-8

3-(2-fluorophenyl)-3,4-dihydroisocoumarin

Conditions
ConditionsYield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 16h; Glovebox; Inert atmosphere;77%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

4-phenyl-6-(thiophen-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile
82127-11-5

4-phenyl-6-(thiophen-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4-phenyl-6-(2-thienyl)pyridine

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-4-phenyl-6-(2-thienyl)pyridine

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;76%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

3,4-dihydro-3-(4'-fluorophenyl)isocoumarine

3,4-dihydro-3-(4'-fluorophenyl)isocoumarine

Conditions
ConditionsYield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 16h; Glovebox; Inert atmosphere;75%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile
54585-47-6

4,6-Dimethyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile

3-cyano-4,6-dimethyl-2-{[2-(methoxycarbonyl)benzyl]thio}pyridine

3-cyano-4,6-dimethyl-2-{[2-(methoxycarbonyl)benzyl]thio}pyridine

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;74%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2-thioxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile
104960-49-8

2-thioxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-6-phenyl-4-(trifluoromethyl)pyridine

3-cyano-2-{[2-(methoxycarbonyl)benzyl]thio}-6-phenyl-4-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With triethylamine In chloroform for 0.5h; Reflux;74%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

1-cyano-2-hydroxynaphthalene
52805-47-7

1-cyano-2-hydroxynaphthalene

C20H15NO3
1293961-06-4

C20H15NO3

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50 - 55℃; for 0.666667h;72%
m-bromobenzoic aldehyde
3132-99-8

m-bromobenzoic aldehyde

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

(dl)-3-(3'-bromophenyl)-3,4-dihydroisocoumarin

(dl)-3-(3'-bromophenyl)-3,4-dihydroisocoumarin

Conditions
ConditionsYield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 16h; Glovebox; Inert atmosphere;71%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

allyltrimethoxysilane
2551-83-9

allyltrimethoxysilane

methyl 5-allyl-2-methylbenzoate

methyl 5-allyl-2-methylbenzoate

Conditions
ConditionsYield
Stage #1: o-(chloromethyl)benzoic acid methyl ester; allyltrimethoxysilane With tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; for 12h; Hiyama Coupling; Inert atmosphere;
Stage #2: With toluene-4-sulfonic acid In tetrahydrofuran; dichloromethane at 20℃; for 0.166667h; Inert atmosphere; regioselective reaction;
70%
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

3-(4-(trifluoromethyl)phenyl)-3,4-dihydroisocoumarin

3-(4-(trifluoromethyl)phenyl)-3,4-dihydroisocoumarin

Conditions
ConditionsYield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 16h; Glovebox; Inert atmosphere;68%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

5-chloro-2-hydroxybenzonitrile
13589-72-5

5-chloro-2-hydroxybenzonitrile

C16H12ClNO3
1293960-94-7

C16H12ClNO3

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50 - 55℃; for 0.666667h;67%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

2-cyano-4-methylphenol
51282-90-7

2-cyano-4-methylphenol

C17H15NO3
1293960-91-4

C17H15NO3

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50 - 55℃; for 0.666667h;65%
o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

benzaldehyde
100-52-7

benzaldehyde

3-phenyl-isochroman-1-one
2674-44-4, 146518-60-7

3-phenyl-isochroman-1-one

Conditions
ConditionsYield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 16h; Reagent/catalyst; Solvent; Temperature; Glovebox; Inert atmosphere;64%
salicylonitrile
611-20-1

salicylonitrile

o-(chloromethyl)benzoic acid methyl ester
34040-62-5

o-(chloromethyl)benzoic acid methyl ester

methyl 2-[(2-cyanobenzyl)oxy]benzoate
1293960-89-0

methyl 2-[(2-cyanobenzyl)oxy]benzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50 - 55℃; for 0.666667h;62%

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