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Cas:3482-14-2
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
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Cas:3482-14-2
Min.Order:1 Metric Ton
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Cas:3482-14-2
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
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Cas:3482-14-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry8-Isoquinolinol CAS:3482-14-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi
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Min.Order:1 Gram
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Type:Lab/Research institutions
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Cas:3482-14-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:3482-14-2
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryHigh Quality Best price Fast Delivery Good Service Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; developm
Cas:3482-14-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
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High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
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Cas:3482-14-2
Min.Order:0
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Type:Lab/Research institutions
inquiryThe process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai
Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
8-Isoquinolinol cas 3482-14-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Conditions | Yield |
---|---|
Stage #1: 8-methoxyisoquinoline With boron tribromide In dichloromethane at 0 - 20℃; for 2.5h; Heating / reflux; Stage #2: With methanol at -78 - 20℃; for 0.5h; Heating / reflux; | 98% |
With boron tribromide In dichloromethane for 1h; demethylation; Heating; | 83% |
8-chloroisoquinoline
isoquinolin-8-ol
Conditions | Yield |
---|---|
With copper acetylacetonate; lithium hydroxide monohydrate; 1,3-bis(4-hydroxy-2,6-dimethylphenyl)urea In water; dimethyl sulfoxide at 130℃; for 24h; Inert atmosphere; | 72% |
Conditions | Yield |
---|---|
biotransformation by Pseudomonas putida UV4; | A 5 mg B 43 mg C 41 mg |
isoquinolin-8-ol
Conditions | Yield |
---|---|
With sulfuric acid; sulfur trioxide at 300℃; Erhitzen des Reaktionsprodukts mit Natriumhydroxid unter Zusatz von Wasser auf 210grad; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: benzene / 5 h / Heating 1.2: ClCO2Et; (MeO)3P / 13 / 72 h / 20 °C 1.3: TiCl4 / 15 / 1 h / Heating 2.1: boron tribromide / dichloromethane / 1 h / Heating View Scheme |
isoquinolin-8-ol
Conditions | Yield |
---|---|
With sodiumsulfide nonahydrate In ethanol at 40℃; for 20h; |
isoquinolin-8-ol
Conditions | Yield |
---|---|
With bromine; sodium hydrogencarbonate In methanol at 20℃; for 0.0833333h; | 96% |
isoquinolin-8-ol
1,2,3,4-tetrahydro-8-hydroxyisoquinoline acetate
Conditions | Yield |
---|---|
With hydrogen; acetic acid; platinum(IV) oxide In ethanol under 3000.3 Torr; for 18h; | 92% |
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In acetonitrile at 20℃; | 90% |
isoquinolin-8-ol
carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester
Conditions | Yield |
---|---|
With (S)-(+)-N-(3,5-dioxa-4-phosphacyclohepta-[2,1-a;3,4-a′]dinaphthalen-4-yl)dibenz[b,f]azepine; bis(1,5-cyclooctadiene)diiridium(I) dichloride In methanol at 25℃; for 0.1h; Inert atmosphere; enantioselective reaction; | 87% |
Conditions | Yield |
---|---|
With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In chloroform at 60℃; | 86% |
isoquinolin-8-ol
carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester
Conditions | Yield |
---|---|
With (S)-(+)-N-(3,5-dioxa-4-phosphacyclohepta-[2,1-a;3,4-a′]dinaphthalen-4-yl)dibenz[b,f]azepine; bis(1,5-cyclooctadiene)diiridium(I) dichloride; 3,5-dichlorobenzoic acid In methanol at 25℃; for 10h; Inert atmosphere; enantioselective reaction; | 78% |
isoquinolin-8-ol
carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester
Conditions | Yield |
---|---|
With (S)-(+)-N-(3,5-dioxa-4-phosphacyclohepta-[2,1-a;3,4-a′]dinaphthalen-4-yl)dibenz[b,f]azepine; bis(1,5-cyclooctadiene)diiridium(I) dichloride In methanol at 25℃; for 0.1h; Inert atmosphere; enantioselective reaction; | 74% |
isoquinolin-8-ol
acetic acid
1,2,3,4-tetrahydro-8-hydroxyisoquinoline acetate
Conditions | Yield |
---|---|
With platinum(IV) oxide; hydrogen at 65℃; for 48h; | 72% |
isoquinolin-8-ol
1,2,3,4-tetrahydroisoquinoline-8-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate; acetic acid at 20℃; for 1h; Cooling; | 71% |
4-chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine
isoquinolin-8-ol
Conditions | Yield |
---|---|
Stage #1: isoquinolin-8-ol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: 4-chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine In N,N-dimethyl-formamide Further stages.; | 63% |
Conditions | Yield |
---|---|
Stage #1: isoquinolin-8-ol With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: propyl bromide In N,N-dimethyl-formamide at 20℃; for 1h; | 63% |
Stage #1: isoquinolin-8-ol With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: propyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 1h; | 63% |
isoquinolin-8-ol
3-acetamido-2,6-dichlorobenzyl methanesulfonate
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide Substitution; | 25% |
isoquinolin-8-ol
(1R,3s,5S)-tert-butyl 3-((1s,4S)-4-hydroxycyclohexyloxy)-8-azabicyclo[3.2.1]octane-8-carboxylate
(1R,3s,5S)-tert-butyl 3-((1r,4R)-4-(isoquinolin-8-yloxy)cyclohexyloxy)-8-azabicyclo[3.2.1]octane-8-carboxylate
Conditions | Yield |
---|---|
With di-isopropyl azodicarboxylate; triethylamine; triphenylphosphine In tetrahydrofuran at 20℃; for 19h; Inert atmosphere; | 16.2% |
isoquinolin-8-ol
Conditions | Yield |
---|---|
With copper(l) iodide; dimethylaminoacetic acid; caesium carbonate In 1,4-dioxane at 120℃; for 24h; Inert atmosphere; Sealed tube; | 12% |
Conditions | Yield |
---|---|
With sulfur dioxide; water unter Druck; |
isoquinolin-8-ol
8-aminoisoquinoline
Conditions | Yield |
---|---|
With ammonium hydroxide; sulfur dioxide at 150 - 160℃; |
isoquinolin-8-ol
4-fluoro-6-(4-(1-(4-fluorophenyl)ethyl)piperazin-1-yl)pyrimidine
Conditions | Yield |
---|---|
With caesium carbonate In dimethyl sulfoxide at 115℃; for 0.5h; |
isoquinolin-8-ol
trimethylsilyl iodide
N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide
N-(trimethylsilyl)trifluoroacetamide
Conditions | Yield |
---|---|
In tetrahydrofuran; dichloromethane; acetonitrile |
isoquinolin-8-ol
1-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-2-bromo-propan-1-one
C24H25N3O3
Conditions | Yield |
---|---|
With caesium carbonate In acetone at 20℃; for 24h; |
isoquinolin-8-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C 1.2: 1 h / 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C 2.2: 0.08 h / 20 °C View Scheme |
isoquinolin-8-ol
1-chloro-8-propoxy-isoquinoline
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C 1.2: 1 h / 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C 2.2: 0.08 h / 20 °C 3.1: trichlorophosphate / 5 h / 90 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C 1.2: 1 h / 0 - 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C 2.2: 0.08 h / 20 °C 3.1: trichlorophosphate / 5 h / 90 °C View Scheme |
isoquinolin-8-ol
A
1-chloro-8-propoxy-isoquinoline-5-sulfonic acid
B
1-chloro-8-propoxy-isoquinoline-7-sulfonic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C 1.2: 1 h / 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C 2.2: 0.08 h / 20 °C 3.1: trichlorophosphate / 5 h / 90 °C 4.1: fuming sulphuric acid / water / 0.5 h / 0 °C View Scheme |
isoquinolin-8-ol
1-chloro-8-propoxy-isoquinoline-5-sulfonic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C 1.2: 1 h / 0 - 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C 2.2: 0.08 h / 20 °C 3.1: trichlorophosphate / 5 h / 90 °C 4.1: sulfur trioxide; sulfuric acid / 0.5 h / 0 °C View Scheme |
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