Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:36070-80-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:36070-80-1
Min.Order:1 Metric Ton
Negotiable
Type:Manufacturers
inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Manufacturers
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:36070-80-1
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:36070-80-1
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:36070-80-1
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:36070-80-1
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:36070-80-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla
Cas:36070-80-1
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:36070-80-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry5-CHLORO-PYRAZINE-2-CARBOXYLIC ACID Chemical Properties Melting point 150-151℃ Boiling point 330.9±37.0 °C(Predicted) density 1.579±0.06 g/cm3(Predicted) storage temp. Keep in dark place,Sealed in dry,Room Temperatur
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry5-CHLORO-PYRAZINE-2-CARBOXYLIC ACID CAS:36070-80-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:36070-80-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:36070-80-1
Min.Order:0
Negotiable
Type:Manufacturers
inquiryAppearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Se
Cas:36070-80-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:36070-80-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:36070-80-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:36070-80-1
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryTop quality 36070-80-1 low price 5-chloro-pyrazine-2-carboxylic acid factory in China Molecular Formula C5H3ClN2O2 Molar Mass 158.54 Density 1.579±0.06 g/cm3(Predicted) Melting Point 150-151℃
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Other
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:36070-80-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white crystal powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:10g/bag,or as your request Application:Used as Pharmaceutical Intermediate
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h
Cas:36070-80-1
Min.Order:0
Negotiable
Type:Other
inquiryProduct name: 5-Chloro-2-Pyrazinecarboxylic Acid CAS No.:36070-80-1 Molecule Formula:C5H3ClN2O2 Molecule Weight:158.54 Purity: 98.0% Package: 25kg/drum Description:Light yellow powder Manufacture Standards:Enterprise Standard
Cas:36070-80-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:36070-80-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:36070-80-1
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Cas:36070-80-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:36070-80-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:36070-80-1
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryLocated in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h
methyl 5-chloropyrazine-2-carboxylate
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With potassium carbonate In tetrahydrofuran; water at 25℃; for 42h; | 96% |
Stage #1: methyl 5-chloropyrazine-2-carboxylate With methanol; sodium hydroxide; water In tetrahydrofuran at 0 - 20℃; for 5h; Stage #2: With hydrogenchloride In tetrahydrofuran; methanol; water | 92% |
With hydrogenchloride; potassium carbonate In tetrahydrofuran; water | 91% |
5-hydroxypyrazinoic acid
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With thionyl chloride In N,N-dimethyl-formamide at 80℃; for 16h; | 93% |
With thionyl chloride; N,N-dimethyl-formamide for 16h; Reflux; | 75% |
Multi-step reaction with 2 steps 1: thionyl chloride; N,N-dimethyl-formamide / 4 h / 75 °C 2: water View Scheme |
4,5-dihydro-5-oxo-2-pyrazinecarboxylic acid
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With phosphorus pentachloride In toluene at 80℃; for 2h; Large scale; | 85.6% |
2-chloro-5-furan-2-yl-pyrazine
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With potassium permanganate; Aliquat 336 In water; benzene at 0 - 40℃; for 4h; | 78% |
With potassium permanganate; Aliquat 336 In water; benzene at 15 - 20℃; for 4.5h; | 76% |
2-Hydroxy-5-(2'-furyl)pyrazine
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 52 percent / POCl3 / 3 h / Heating 2: 76 percent / KMnO4 / tricaprylmethylammonium chloride / benzene; H2O / 4.5 h / 15 - 20 °C View Scheme |
methyl 5-chloropyrazine-2-carboxylate
hexan-1-ol
A
5-(hexyloxy)pyrazine-2-carboxylic acid
B
hexyl 5-hexyloxypyrazine-2-carboxylate
C
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Stage #1: hexan-1-ol With sodium at 60℃; for 0.75h; Stage #2: methyl 5-chloropyrazine-2-carboxylate at 50℃; for 0.583333h; |
5-chloropyrazine-2-carbonyl chloride
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With water |
1,6-dihydro-6-oxo-2,3-pyrazinedicarbonitrile
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: sodium hydroxide / water / 6 h / 100 °C / Large scale 2.1: Aliquat 336 / sulfolane; toluene / 2.5 h / 150 °C / Dean-Stark; Large scale 2.2: Large scale 3.1: phosphorus pentachloride / toluene / 2 h / 80 °C / Large scale View Scheme |
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: Aliquat 336 / sulfolane; toluene / 2.5 h / 150 °C / Dean-Stark; Large scale 1.2: Large scale 2.1: phosphorus pentachloride / toluene / 2 h / 80 °C / Large scale View Scheme |
5-chloropyrazinoic acid
5-hydroxypyrazinoic acid
Conditions | Yield |
---|---|
With sodium hydroxide for 1h; Heating; | 100% |
5-chloropyrazinoic acid
5-chloropyrazine-2-carbonyl chloride
Conditions | Yield |
---|---|
With (COCl)2; N-methyl-acetamide In dichloromethane | 100% |
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane | 100% |
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 0 - 20℃; | 100% |
5-chloropyrazinoic acid
diazomethyl-trimethyl-silane
methyl 5-chloropyrazine-2-carboxylate
Conditions | Yield |
---|---|
In methanol; diethyl ether for 0.5h; | 100% |
methyl 4-hydroxy-2-methyl-2H-indazole-6-carboxylate
5-chloropyrazinoic acid
5-chloropyrazine-2-carbonyl chloride
Conditions | Yield |
---|---|
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 23℃; for 18h; | 100% |
oxetan-2-ylmethanol
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With potassium tert-butylate In N,N-dimethyl-formamide at 120℃; for 0.5h; Sealed tube; Microwave irradiation; | 99% |
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With 2-chloro-1-methyl-pyridinium iodide In 1-methyl-pyrrolidin-2-one at 20℃; for 2h; Inert atmosphere; | 99% |
trifluoroethylamine
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; | 98.9% |
With HATU In dichloromethane; N,N-dimethyl-formamide at 20℃; Inert atmosphere; | 72.8% |
tert-Butyl 2,2,2-trichloroacetimidate
5-chloropyrazinoic acid
5-chloropyrazine-2-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With boron trifluoride dimethyl etherate In tetrahydrofuran; cyclohexane at 25℃; for 16h; | 94% |
Stage #1: tert-Butyl 2,2,2-trichloroacetimidate; 5-chloropyrazinoic acid In tetrahydrofuran; cyclohexane at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: With boron trifluoride dimethyl etherate In tetrahydrofuran; cyclohexane at 20℃; for 16h; Inert atmosphere; | 94% |
With boron trifluoride diethyl etherate In tetrahydrofuran; cyclohexane at 25℃; for 16h; | 92% |
sodium methylate
5-chloropyrazinoic acid
5-methoxy-pyrazine-2-carboxylic acid
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With sulfuric acid In methanol at 65℃; for 4h; Stage #2: sodium methylate In methanol at 20℃; for 0.5h; Stage #3: With sodium hydroxide In methanol; water at 40℃; for 1h; | 94% |
(R)-tert-butyl 2-methylpiperazine-1-carboxylate
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 2h; | 92% |
difluoroethanol
5-chloropyrazinoic acid
5-(2,2-difluoroethoxy)pyrazine-2-carboxylic acid
Conditions | Yield |
---|---|
With potassium tert-butylate In N,N-dimethyl-formamide at 20 - 100℃; Inert atmosphere; | 91% |
dimethyl amine
5-chloropyrazinoic acid
5-chloro-N,N-dimethylpyrazine-2-carboxamide
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20 - 25℃; for 2.16667h; Stage #2: dimethyl amine In tetrahydrofuran; dichloromethane at 20 - 25℃; for 3.16667h; | 91% |
Stage #1: 5-chloropyrazinoic acid With thionyl chloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2.16667h; Stage #2: dimethyl amine With triethylamine In dichloromethane at 20℃; for 2h; | 91% |
Stage #1: 5-chloropyrazinoic acid With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.333333h; Stage #2: dimethyl amine With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 2h; | 71.18% |
5-chloropyrazinoic acid
2-chloro-5-(trifluoromethyl)-pyrazine
Conditions | Yield |
---|---|
With sulfur tetrafluoride; hydrogen fluoride at -40 - 80℃; for 6h; Temperature; Autoclave; | 90% |
tert-butyl N-[(4aR,6S,11bR)-10-amino-3,3,6,11b-tetramethyl-4,4-dioxo-5,6-dihydro-4aH-[1]benzoxepino[4,5-b][1,4]thiazin-2-yl]-N-tert-butoxycarbonylcarbamate
5-chloropyrazinoic acid
tert-butyl N-[(4aR,6S,11bR)-10-[(5-chloropyrazine-2-carbonyl)amino]-3,3,6,11b-tetramethyl-4,4-dioxo-5,6-dihydro-4aH-[1]benzoxepino[4,5-b][1,4]thiazin-2-yl]-N-tert-butoxycarbonylcarbamate
Conditions | Yield |
---|---|
With pyridine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h; Sealed tube; | 87% |
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In dichloromethane; ethyl acetate at 20℃; | 83% |
azetidine
5-chloropyrazinoic acid
azetidin-1-yl(5-chloropyrazin-2-yl)methanone
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 2h; Stage #2: azetidine With triethylamine In dichloromethane at 20℃; for 72h; | 82% |
methanol
5-chloropyrazinoic acid
methyl 5-chloropyrazine-2-carboxylate
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With thionyl chloride at 80℃; for 2h; Stage #2: methanol at 50℃; for 2h; | 81% |
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h; Time; | 65% |
With thionyl chloride at 0 - 70℃; for 2h; | 4.5 g |
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1,2-dichloro-ethane; triethylamine In dichloromethane at 20℃; for 0.5h; | 80% |
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In tetrahydrofuran; ethyl acetate at 20℃; for 2h; Alkaline conditions; | 77% |
5-chloropyrazinoic acid
5-chloro-N-[(1R)-2,2,2-trifluoro-1-methylethyl]pyrazine-2-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; | 76% |
5-chloropyrazinoic acid
(5-chloro-2-pyrazinyl)methanol
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With oxalyl dichloride In 1,4-dioxane; N,N-dimethyl-formamide at 20℃; Inert atmosphere; Stage #2: With sodium hydroxide In 1,4-dioxane; water at 5℃; Inert atmosphere; | 75% |
Multi-step reaction with 2 steps 1: diethyl ether; methanol / 0.5 h 2: diisobutylaluminium hydride / tetrahydrofuran / 2 h / 0 °C View Scheme |
ethanolamine
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Stage #1: 5-chloropyrazinoic acid With triethylamine; isobutyl chloroformate In dichloromethane at 0℃; for 0.333333h; Stage #2: ethanolamine In dichloromethane at 0 - 20℃; for 1h; | 75% |
(S)-1,1,1-trifluoropropan-2-amine
5-chloropyrazinoic acid
5-chloro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrazine-2-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; | 73% |
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; | 73% |
(S)-1-cyclopropyl-2,2,2-trifluoroethan-1-amine hydrochloride
5-chloropyrazinoic acid
5-chloro-N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]pyrazine-2-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; | 72% |
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
Stage #1: 2-amino-3,5-bis(4-trifluoromethylphenyl)pyrazine With 1-methyl-1H-imidazole; methanesulfonyl chloride In dichloromethane at 0 - 20℃; for 0.75h; Stage #2: 5-chloropyrazinoic acid In dichloromethane at 0 - 45℃; for 4h; Reflux; | 72% |
carbostyril 124
5-chloropyrazinoic acid
Conditions | Yield |
---|---|
With tin; copper; potassium carbonate Reflux; | 71% |
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