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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Bromo-2-fluorobenzotrifluoride Manufacturer/High quality/Best price/In stock

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Bromo-2-Fluorobenzotrifluoride

Cas:393-37-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2-fluoro-5-bromobenzotrifluoride

Cas:393-37-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2-Fluoro-5-bromobenzotrifluoride 393-37-3

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 393-37-3 with best quality

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 5-Bromo-2-fluorobenzotrifluoride Synonyms: 4-Bromo-1-fluoro-2-(trifluoromethyl)benzene CAS:393-37-3 MF: C7H3BrF4 Appearance:Colorless transparent liquid, Storage: Preserve in well-closed, light-resistant and airtight containers. Package

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzene,4-bromo-1-fluoro-2-(trifluoromethyl)- 393-37-3

Cas:393-37-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2-Fluoro-5-bromobenzotrifluoride

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $85.0 / 100.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzene,4-bromo-1-fluoro-2-(trifluoromethyl)-/ LIDE PHARMA- Factory supply / Best price

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:393-37-3

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Bromo-2-Fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Fluoro-5-bromobenzotrifluoride

Cas:393-37-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Bromo-6-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 2-Fluoro-5-bromobenzotrifluoride

Cas:393-37-3

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

5-Bromo-2-fluorobenzo-trifluoride 393-37-3

Cas:393-37-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2-Fluoro-5-bromobenzotrifluoride Synonyms: 5-Bromo-alpha,alpha,alpha,2-tetrafluorotoluene 4-Bromo-1-fluoro-2-(trifluoromethyl)benzene;5--2-of fluorinebroMinethree fluorine toluene;2-FLUORO-5-BROMO BENZOTRIFLUORIDE;4-BROMO-1-FLUORO

4-Fluoro-3-trifluoromethylbromobenzene 393-37-3 C7H3BrF4

Cas:393-37-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Fluoro-5-bromobenzotrifluoride

Cas:393-37-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/4-Fluoro-3-trifluoromethylbromobenzene

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

4-Fluoro-3-trifluoromethylbromobenzene

Cas:393-37-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

5-Bromo-2-fluorobenzotrifluoride Manufacturer/High quality/Best price/In stock CAS NO.393-37-3

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-Bromo-2-fluorobenzotrifluoride cas no. 393-37-3 98%

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

4-Bromo-1-fluoro-2-(trifluoromethyl)benzene

Cas:393-37-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

5-Bromo-2-fluorobenzotrifluoride

Cas:393-37-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Bromo-4-Fluorobenzotrifluoride

Cas:393-37-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4-Fluoro-3-trifluoromethylaniline
2357-47-3

4-Fluoro-3-trifluoromethylaniline

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

Conditions
ConditionsYield
With tert.-butylnitrite; copper(ll) bromide In acetonitrile at 20℃; Cooling with ice; Inert atmosphere;
With tert.-butylnitrite; copper(ll) bromide In acetonitrile at 20℃; for 2h; Inert atmosphere; Cooling with ice;
With tert.-butylnitrite; copper(ll) bromide In acetonitrile at 20℃; for 2h; Cooling with ice; Inert atmosphere;
With tert.-butylnitrite; copper(ll) bromide In acetonitrile at 20℃; for 2h; Inert atmosphere; Cooling with ice;2 g
1-fluoro-2-trifluoromethylbenzene
392-85-8

1-fluoro-2-trifluoromethylbenzene

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

Conditions
ConditionsYield
With ferric(III) bromide; sulfuric acid; tetrabutylammomium bromide; bromine; lithium bromide at 35 - 45℃; for 6h;93.98%
5-bromo-1-trifluoromethyl-benzenediazonium-(2)-tetrafluoroborate

5-bromo-1-trifluoromethyl-benzenediazonium-(2)-tetrafluoroborate

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

5-bromo-2-fluoro-3-(trifluoromethyl)benzaldehyde
1291487-26-7

5-bromo-2-fluoro-3-(trifluoromethyl)benzaldehyde

Conditions
ConditionsYield
Stage #1: 5-bromo-2-fluorobenzotrifluoride With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78 - 20℃; Inert atmosphere;
72%
Stage #1: 5-bromo-2-fluorobenzotrifluoride With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78℃; for 1h;
71.7%
Stage #1: 5-bromo-2-fluorobenzotrifluoride With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78℃; for 1h;
71.7%
Stage #1: 5-bromo-2-fluorobenzotrifluoride With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78℃; for 1h;
71.7%
Stage #1: 5-bromo-2-fluorobenzotrifluoride With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl-formamide In N,N-dimethyl-formamide at -78℃; for 1h;
71.7%
pyrrolidin-3-ol
40499-83-0

pyrrolidin-3-ol

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

1-[4-fluoro-3-(trifluoromethyl)phenyl]pyrrolidin-3-ol
1198181-19-9

1-[4-fluoro-3-(trifluoromethyl)phenyl]pyrrolidin-3-ol

Conditions
ConditionsYield
With caesium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 90℃; for 16h; Inert atmosphere;58%
With caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate In toluene at 90℃; for 16h; Inert atmosphere;58%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

(4-bromo-2-(trifluoromethyl)phenyl)(methyl)sulfane
300356-31-4

(4-bromo-2-(trifluoromethyl)phenyl)(methyl)sulfane

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 50℃; for 2h;94%
In water; N,N-dimethyl-formamide at 50℃; for 2h;94%
In N,N-dimethyl-formamide at 50℃; for 1h;
In N,N-dimethyl-formamide at 20 - 50℃;
In N,N-dimethyl-formamide at 50℃; for 1h;
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

4-(4-fluoro-3-trifluoromethyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
1221069-81-3

4-(4-fluoro-3-trifluoromethyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 100℃; for 24h; Heating;100%
ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

2,2,2-trifluoro-1-[4-fluoro-3-(trifluoromethyl)phenyl]ethanone
1335013-55-2

2,2,2-trifluoro-1-[4-fluoro-3-(trifluoromethyl)phenyl]ethanone

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; hexane at -100 - -20℃;86%
3-phenyl-2,2-bis(3-(trifluoromethoxy)phenyl)propan-1-amine
1032189-06-2

3-phenyl-2,2-bis(3-(trifluoromethoxy)phenyl)propan-1-amine

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

4-fluoro-N-(3-phenyl-2,2-bis(3-(trifluoromethoxy)phenyl)propyl)-3-(trifluoromethyl)benzenamine
1032187-97-5

4-fluoro-N-(3-phenyl-2,2-bis(3-(trifluoromethoxy)phenyl)propyl)-3-(trifluoromethyl)benzenamine

Conditions
ConditionsYield
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) In toluene at 100℃;32%
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
61676-62-8

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

2-(4-Fluoro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

2-(4-Fluoro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Conditions
ConditionsYield
Stage #1: 5-bromo-2-fluorobenzotrifluoride With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran; hexane at 20℃; for 12h; Inert atmosphere;
82%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

3-hydroxy-benzeneacetic acid, methyl ester
42058-59-3

3-hydroxy-benzeneacetic acid, methyl ester

methyl 2-[3-[4-bromo-2-(trifluoromethyl)phenoxy]phenyl]acetate

methyl 2-[3-[4-bromo-2-(trifluoromethyl)phenoxy]phenyl]acetate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 100℃;55%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

isopropyl alcohol
67-63-0

isopropyl alcohol

4-bromo-1-[(1-methylethyl)oxy]-2-(trifluoromethyl)benzene
914635-61-3

4-bromo-1-[(1-methylethyl)oxy]-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
Stage #1: isopropyl alcohol With potassium tert-butylate In tetrahydrofuran at 50℃; for 0.166667h; Inert atmosphere;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 50℃;
Stage #1: isopropyl alcohol With potassium tert-butylate In tetrahydrofuran at 50℃; for 0.166667h; Inert atmosphere;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 50℃;
Stage #1: isopropyl alcohol With potassium tert-butylate In tetrahydrofuran at 50℃; for 0.166667h; Inert atmosphere;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 50℃;
Stage #1: isopropyl alcohol With potassium tert-butylate In tetrahydrofuran at 50℃; for 0.166667h;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 50℃;
5.21 g
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

6-chloropyridin-3-ylboronic acid
444120-91-6

6-chloropyridin-3-ylboronic acid

C12H6ClF4N

C12H6ClF4N

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In tetrahydrofuran; water at 70℃; for 2h; Inert atmosphere; Reflux;53%
octanol
111-87-5

octanol

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

4-bromo-1-(octyloxy)-2-(trifluoromethyl)benzene
161712-25-0

4-bromo-1-(octyloxy)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran Heating / reflux;100%
t-butylsulfonamide
34813-49-5

t-butylsulfonamide

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

N-(4-bromo-2-(trifluoromethyl)phenyl)-2-methylpropane-2-sulfonamide
1442431-99-3

N-(4-bromo-2-(trifluoromethyl)phenyl)-2-methylpropane-2-sulfonamide

Conditions
ConditionsYield
Stage #1: t-butylsulfonamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In N,N-dimethyl-formamide; mineral oil at 120℃;
31%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

4-pyridylboronic acid
1692-15-5

4-pyridylboronic acid

4-(4-fluoro-3-trifluoromethyl-phenyl)-pyridine
388118-59-0

4-(4-fluoro-3-trifluoromethyl-phenyl)-pyridine

Conditions
ConditionsYield
With palladium diacetate; triphenylphosphine In propan-1-ol; water for 4h; Suzuki coupling; Heating;82%
With sodium carbonate; triphenylphosphine; palladium diacetate In propan-1-ol; hexane; water
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

2-(Dimethylaminophenylmethyl)cyclohexanone
94318-23-7

2-(Dimethylaminophenylmethyl)cyclohexanone

2-(dimethylaminophenylmethyl)-1-(4-fluoro-3-trifluoromethylphenyl)cyclohexanol, hydrochloride
300658-92-8

2-(dimethylaminophenylmethyl)-1-(4-fluoro-3-trifluoromethylphenyl)cyclohexanol, hydrochloride

Conditions
ConditionsYield
With magnesium In ethyl acetate63.7%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

(S)-2-amino-2,4-dimethylpentan-1-ol

(S)-2-amino-2,4-dimethylpentan-1-ol

(S)-1-(4-bromo-2-(trifluoromethyl)phenoxy)-2,4-dimethylpentan-2-amine

(S)-1-(4-bromo-2-(trifluoromethyl)phenoxy)-2,4-dimethylpentan-2-amine

Conditions
ConditionsYield
Stage #1: (S)-2-amino-2,4-dimethylpentan-1-ol With potassium tert-butylate In tetrahydrofuran for 0.0833333h; Inert atmosphere;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
Stage #1: (S)-2-amino-2,4-dimethylpentan-1-ol With potassium tert-butylate In tetrahydrofuran for 0.0833333h; Inert atmosphere;
Stage #2: 5-bromo-2-fluorobenzotrifluoride In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
2-(4-Fluorophenyl)ethanol
7589-27-7

2-(4-Fluorophenyl)ethanol

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

4-bromo-1-(4-fluorophenethoxy)-2-(trifluoromethyl)benzene

4-bromo-1-(4-fluorophenethoxy)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide for 2h;62%
2-(phenyl)pyrrolidine
1006-64-0

2-(phenyl)pyrrolidine

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

1-(4-bromo-2-(trifluoromethyl)phenyl)-2-phenylpyrrolidine

1-(4-bromo-2-(trifluoromethyl)phenyl)-2-phenylpyrrolidine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 150℃; Sealed tube;4.9%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

methyl(2-hydroxyethyl)carbamic acid tert-butyl ester
57561-39-4

methyl(2-hydroxyethyl)carbamic acid tert-butyl ester

tert-butyl 2-(4-bromo-2-(trifluoromethyl)phenoxy)ethyl(methyl)carbamate
1315465-33-8

tert-butyl 2-(4-bromo-2-(trifluoromethyl)phenoxy)ethyl(methyl)carbamate

Conditions
ConditionsYield
With sodium hydride; triethylamine In N,N-dimethyl-formamide at 20℃;
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

2-(4-Fluoro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

2-(4-Fluoro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 110℃; for 0.166667h; Miyaura Borylation Reaction; Microwave irradiation;
3-oxabicyclo[3.1.0]hexane-2,4-dione
5617-74-3

3-oxabicyclo[3.1.0]hexane-2,4-dione

5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

2-[4-fluoro-3-(trifluoromethyl)benzoyl]cyclopropane-1-carboxylic acid

2-[4-fluoro-3-(trifluoromethyl)benzoyl]cyclopropane-1-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromo-2-fluorobenzotrifluoride With iodine; magnesium In tetrahydrofuran at 40℃;
Stage #2: 3-oxabicyclo[3.1.0]hexane-2,4-dione In tetrahydrofuran at -73℃; for 0.5h;
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

4-tert-butyl-dimethylsilyloxyphenylboronic acid anhydride
123088-32-4

4-tert-butyl-dimethylsilyloxyphenylboronic acid anhydride

4'-fluoro-3'-trifluoromethyl-biphenyl-4-ol
634192-41-9

4'-fluoro-3'-trifluoromethyl-biphenyl-4-ol

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 95℃; Suzuki reaction;62%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

C13H14BBrF4O2

C13H14BBrF4O2

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 20℃; for 24h; Catalytic behavior; Inert atmosphere; Glovebox;62%
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; Glovebox;62%
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

A

5-bromo-2-fluoro-1-nitro-3-trifluoromethyl-benzene
889459-12-5

5-bromo-2-fluoro-1-nitro-3-trifluoromethyl-benzene

B

1-bromo-4-fluoro-2-nitro-5-trifluoromethyl-benzene
889459-13-6

1-bromo-4-fluoro-2-nitro-5-trifluoromethyl-benzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 15 - 30℃; for 4h;
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

sodium thioethylate
811-51-8

sodium thioethylate

4-bromo-1-(ethylthio)-2-(trifluoromethyl)-benzene
873194-97-9

4-bromo-1-(ethylthio)-2-(trifluoromethyl)-benzene

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50℃; for 1.5h;
5-bromo-2-fluorobenzotrifluoride
393-37-3

5-bromo-2-fluorobenzotrifluoride

potassium cyanide
151-50-8

potassium cyanide

4-bromo-2-(trifluoromethyl)benzonitrile
191165-13-6

4-bromo-2-(trifluoromethyl)benzonitrile

Conditions
ConditionsYield
In dimethyl sulfoxide at 80℃; for 14h;

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