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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(-)-Corey lactone aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (-)-Corey Lactone Aldehyde Benzoate supplier in China

Cas:39746-01-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality (-)-Corey aldehyde benzoate CAS 39746-01-5 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food

High quality (-)-Corey aldehyde benzoate CAS 39746-01-5 with factory price

Cas:39746-01-5

Min.Order:10 Gram

FOB Price: $10.0

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(3aR,4R,5R,6aS)-5-(Benzoyloxy)-hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde

Cas:39746-01-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(-)-5-(benzoyloxy)hexahydro-2-oxo-2H-cyclo-penta

Cas:39746-01-5

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 39746-01-5 with competitive price

Cas:39746-01-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(-)-Corey aldehyde benzoate 39746-01-5

Cas:39746-01-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

(-)-Corey aldehyde benzoate CAS:39746-01-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

(-)-Corey aldehyde benzoate CAS:39746-01-5

Cas:39746-01-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality (-)-Corey aldehyde benzoate CAS NO.39746-01-5

Cas:39746-01-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Saiwante (shanghai) New Material Technology Co., Ltd.

ProName:High quality (-)-Corey aldehyde benzoa... CasNo:39746-01-5 Molecular Formula:C15H14O5 Appearance:White Powder Application:Biologic Chemical DeliveryTime:Prompt PackAge:1kg/foil bag Port:shanghai ProductionCapacity:30 Kilogram/Month

(-)-Corey aldehyde benzoate CAS NO.39746-01-5

Cas:39746-01-5

Min.Order:1 Gram

FOB Price: $5.0 / 6.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (-)-5-(benzoyloxy)hexahydro-2-oxo-2H-cyclo -penta

Cas:39746-01-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality (-)-Corey Lactone Aldehyde Benzoate

Cas:39746-01-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(-)-Coreyaldehydebenzoate

Cas:39746-01-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2H-Cyclopenta[b]furan-4-carboxaldehyde,5-(benzoyloxy)hexahydro-2-oxo-, (3aR,4R,5R,6aS)-

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

(-)-5-(benzoyloxy)hexahydro-2-oxo-2H-cyclo-penta

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Other

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Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity (-)-Corey Lactone Aldehyde Benzoate 39746-01-5

Cas:39746-01-5

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

(-)-Corey Lactone Aldehyde Benzoate

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Manufacturers

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(-)-Corey aldehyde benzoate

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

(-)-Corey aldehyde benzoate CAS No.39746-01-5

Cas:39746-01-5

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
39746-00-4

(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

Conditions
ConditionsYield
With Dess-Martin periodane In dichloromethane at 0 - 20℃; for 1h;100%
With Dess-Martin periodane In dichloromethane at 0 - 10℃; for 2h;96.7%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; carbonic acid dimethyl ester In ethyl acetate at 0 - 5℃; Inert atmosphere;95.6%
(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
39746-00-4

(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one

A

(1S,5S)-3-oxo-2-oxabicyclo<3.3.0>oct-6-en-6-carbaldehyde
51260-12-9

(1S,5S)-3-oxo-2-oxabicyclo<3.3.0>oct-6-en-6-carbaldehyde

B

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

Conditions
ConditionsYield
With sulfur trioxide pyridine complex Inert atmosphere;
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(1S,5S)-3-oxo-2-oxabicyclo<3.3.0>oct-6-en-6-carbaldehyde
51260-12-9

(1S,5S)-3-oxo-2-oxabicyclo<3.3.0>oct-6-en-6-carbaldehyde

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at -78℃; for 1h; Elimination;100%
dimethyl (7-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate
500871-68-1

dimethyl (7-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-4-(E)-8-(tert-butyldimethylsilyloxy)-3-oxooct-1-enyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate

(3aR,4R,5R,6aS)-4-(E)-8-(tert-butyldimethylsilyloxy)-3-oxooct-1-enyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
Stage #1: dimethyl (7-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran; mineral oil at 0 - 20℃; for 2.5h; Inert atmosphere;
100%
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

Benzoic acid (3aR,4R,5R,6aS)-4-((E)-2-ethoxycarbonyl-vinyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester
1027275-03-1

Benzoic acid (3aR,4R,5R,6aS)-4-((E)-2-ethoxycarbonyl-vinyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
In benzene at 20℃; for 0.5h; Wittig reaction;98%
1-(triphenylphosphoranylidene)-2-hexanone
41693-11-2

1-(triphenylphosphoranylidene)-2-hexanone

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

C21H24O5

C21H24O5

Conditions
ConditionsYield
In dichloromethane at 20 - 25℃; for 8h; Wittig Olefination;97.1%
dimethyl 2-oxoheptylphosphonate
36969-89-8

dimethyl 2-oxoheptylphosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

A

(3aR,6aS)-4-((E)-3-Oxo-oct-1-enyl)-3,3a,6,6a-tetrahydro-cyclopenta[b]furan-2-one
49673-16-7

(3aR,6aS)-4-((E)-3-Oxo-oct-1-enyl)-3,3a,6,6a-tetrahydro-cyclopenta[b]furan-2-one

B

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; Horner-Emmons reaction;A 1%
B 96%
2-oxohexylphosphonic acid dimethyl ester
61728-15-2

2-oxohexylphosphonic acid dimethyl ester

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; Inert atmosphere;96%
(2,2-difluoro-3-phenoxypropyl) diethyl phosphate

(2,2-difluoro-3-phenoxypropyl) diethyl phosphate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate
209861-00-7

(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
Stage #1: (2,2-difluoro-3-phenoxypropyl) diethyl phosphate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 30℃; for 0.25h; Inert atmosphere; Cooling with ice;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran; mineral oil at 40℃; for 2h;
93.6%
dimethyl 2-oxoheptylphosphonate
36969-89-8

dimethyl 2-oxoheptylphosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
Stage #1: dimethyl 2-oxoheptylphosphonate With lithium hydroxide In tert-butyl methyl ether at 20℃; for 1h;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tert-butyl methyl ether; water at 20℃; for 1h;
91.5%
Stage #1: dimethyl 2-oxoheptylphosphonate; (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one With lithium chloride In tetrahydrofuran; dichloromethane at -20℃; for 2.5h;
Stage #2: With triethylamine In tetrahydrofuran; dichloromethane at -5℃; for 19h;
dimethyl (3-phenoxy-2-oxopropyl)phosphonate
40665-68-7

dimethyl (3-phenoxy-2-oxopropyl)phosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
51638-91-6

(3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
With sodium hydride Horner-Emmons reaction;90%
Stage #1: dimethyl (3-phenoxy-2-oxopropyl)phosphonate With sodium hydride; zinc(II) chloride In tetrahydrofuran; mineral oil at 25 - 35℃; for 0.416667h; Inert atmosphere;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran; dichloromethane; mineral oil at 25 - 40℃; for 2.08333h; Inert atmosphere;
61%
Stage #1: dimethyl (3-phenoxy-2-oxopropyl)phosphonate With sodium hydroxide; zinc(II) chloride In tetrahydrofuran at 27℃; Inert atmosphere;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran at 27℃; for 15h; Inert atmosphere;
50%
4-phenyl-1-(1-phenyl-1H-tetrazole-5-sulfonyl)butan-2-one
1174193-89-5

4-phenyl-1-(1-phenyl-1H-tetrazole-5-sulfonyl)butan-2-one

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-2-oxo-4-((1E)-3-oxo-5-phenylpent-1-en-1-yl)-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
55076-60-3

(3aR,4R,5R,6aS)-2-oxo-4-((1E)-3-oxo-5-phenylpent-1-en-1-yl)-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
With potassium tert-butylate In dichloromethane; tert-butyl alcohol at -60 - -55℃; Solvent; Inert atmosphere;89.43%
dimethyl(2-oxo-4-phenylbutyl)phosphonate
41162-19-0

dimethyl(2-oxo-4-phenylbutyl)phosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-2-oxo-4-((1E)-3-oxo-5-phenylpent-1-en-1-yl)-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
55076-60-3

(3aR,4R,5R,6aS)-2-oxo-4-((1E)-3-oxo-5-phenylpent-1-en-1-yl)-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
Stage #1: dimethyl(2-oxo-4-phenylbutyl)phosphonate With N-ethyl-N,N-diisopropylamine; lithium chloride In acetonitrile at -15℃;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In acetonitrile at -15℃; Wittig Reaction;
84.7%
With triethylamine; lithium chloride In tetrahydrofuran; dichloromethane at 0℃; for 2h; Horner-Wadsworth-Emmons Olefination; Cooling with ice;73%
Stage #1: dimethyl(2-oxo-4-phenylbutyl)phosphonate With sodium hexamethyldisilazane In 1,2-dimethoxyethane Metallation;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In 1,2-dimethoxyethane Condensation;
With n-butyllithium In tetrahydrofuran; hexane; dichloromethane; acetic acid
With triethylamine; lithium chloride In dichloromethane at 0℃; for 2h; Horner-Emmons reaction;
dimethyl diazo-2-oxopropylphosphonate
815610-17-4

dimethyl diazo-2-oxopropylphosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

C16H14O4

C16H14O4

Conditions
ConditionsYield
With potassium carbonate In methanol at 0 - 5℃; for 12.5h;81.9%
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

dimethyl (2-oxoheptyl)phosphonate

dimethyl (2-oxoheptyl)phosphonate

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
Stage #1: dimethyl (2-oxoheptyl)phosphonate With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran at 20℃; for 1.5h;
80%
1-(triphenylphosphoranylidene)-2-heptanone
33803-58-6

1-(triphenylphosphoranylidene)-2-heptanone

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
at 20 - 30℃; for 8h; Time; Wittig Olefination;79.2%
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

{2-[(3-methoxymethyl-phenyl)methyl]-2-oxo-ethyl}phosphonic acid dimethyl ester
256382-39-5

{2-[(3-methoxymethyl-phenyl)methyl]-2-oxo-ethyl}phosphonic acid dimethyl ester

(3aR,4R,5R,6aS)-4-[(1E)-4-[3-(methoxymethyl)phenyl]-3-oxo-1-buten-1-yl]-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
1175629-43-2

(3aR,4R,5R,6aS)-4-[(1E)-4-[3-(methoxymethyl)phenyl]-3-oxo-1-buten-1-yl]-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
Stage #1: {2-[(3-methoxymethyl-phenyl)methyl]-2-oxo-ethyl}phosphonic acid dimethyl ester With sodium hydride In tetrahydrofuran at 20℃; Inert atmosphere;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran for 0.5h; Honer-Emmons reaction; Inert atmosphere;
73.7%
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
39746-00-4

(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol; dichloromethane at 0℃; for 0.416667h;69%
With sodium tetrahydroborate In methanol
With sodium tetrahydroborate In methanol; dichloromethane
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate
336625-17-3

dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Benzoic acid (3aR,4R,5R,6aS)-4-[(E)-4-(2-iodo-5-trifluoromethyl-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester
336625-19-5

Benzoic acid (3aR,4R,5R,6aS)-4-[(E)-4-(2-iodo-5-trifluoromethyl-phenoxy)-3-oxo-but-1-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
With triethylamine; lithium chloride In tetrahydrofuran at 5 - 20℃; for 3.33333h;60%
C15H27(2)H6O5PSi
1352751-86-0

C15H27(2)H6O5PSi

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

C28H34(2)H6O6Si

C28H34(2)H6O6Si

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at -10 - 20℃; Inert atmosphere;54%
Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(1S,5R,6R,7R)-7-(benzoyloxy)-6-vinyl-2-oxabicyclo[3.3.0]octan-3-one
618387-07-8

(1S,5R,6R,7R)-7-(benzoyloxy)-6-vinyl-2-oxabicyclo[3.3.0]octan-3-one

Conditions
ConditionsYield
Stage #1: Methyltriphenylphosphonium bromide With sodium hexamethyldisilazane In tetrahydrofuran at -30℃; for 0.5h; Inert atmosphere;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
51%
With potassium tert-butylate In tetrahydrofuran Wittig olefination;
dimethyl 4-(3-trifluoromethylphenyl)-2-oxobutylphosphonate
70783-99-2

dimethyl 4-(3-trifluoromethylphenyl)-2-oxobutylphosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

Benzoic acid (3aR,4R,5R,6aS)-2-oxo-4-[(E)-3-oxo-5-(3-trifluoromethyl-phenyl)-pent-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
294856-03-4

Benzoic acid (3aR,4R,5R,6aS)-2-oxo-4-[(E)-3-oxo-5-(3-trifluoromethyl-phenyl)-pent-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
Stage #1: dimethyl 4-(3-trifluoromethylphenyl)-2-oxobutylphosphonate With sodium hexamethyldisilazane In 1,2-dimethoxyethane Metallation;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In 1,2-dimethoxyethane Condensation;
50%
dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate
50889-46-8

dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxooct-1-enyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate

(3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxooct-1-enyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate

Conditions
ConditionsYield
Stage #1: dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate With lithium hydroxide In tert-butyl methyl ether at 20℃; for 1h;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tert-butyl methyl ether; water at 20℃; for 3h; Product distribution / selectivity;
49.5%
Stage #1: dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate With lithium hydride In tert-butyl methyl ether at 20℃; for 2h;
Stage #2: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tert-butyl methyl ether at 20℃; for 6h; Product distribution / selectivity;
4.8%
Stage #1: dimethyl (3,3-difluoro-2-oxoheptyl)-phosphonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: With zinc(II) chloride In tetrahydrofuran; mineral oil at 26℃; for 0.5h; Inert atmosphere;
Stage #3: (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one In tetrahydrofuran; mineral oil at 25 - 45℃; for 20h;
dimethyl 2-oxoheptylphosphonate
36969-89-8

dimethyl 2-oxoheptylphosphonate

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

A

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester
40834-86-4

(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester

B

Benzoic acid (3aR,4R,5R,6aS)-2-oxo-4-((Z)-3-oxo-oct-1-enyl)-hexahydro-cyclopenta[b]furan-5-yl ester

Benzoic acid (3aR,4R,5R,6aS)-2-oxo-4-((Z)-3-oxo-oct-1-enyl)-hexahydro-cyclopenta[b]furan-5-yl ester

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at -78 - 20℃; Horner-Emmons reaction;A n/a
B 20%
methyl 2,2,5-trimethylhex-4-enoate
66478-19-1

methyl 2,2,5-trimethylhex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.10Z.13E)-(8R.12R.15S)-15-Hydroxy-9-oxo-16.16.19-trimethyl-5.10.13.18-prostatetraensaeure-methylester

(5Z.10Z.13E)-(8R.12R.15S)-15-Hydroxy-9-oxo-16.16.19-trimethyl-5.10.13.18-prostatetraensaeure-methylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

methyllithium
917-54-4

methyllithium

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.13E)-(8R.11R.12R.15R)-15-Hydroxy-9-oxo-11.19-dimethyl-5.13.18-prostatriensaeure-methylester

(5Z.13E)-(8R.11R.12R.15R)-15-Hydroxy-9-oxo-11.19-dimethyl-5.13.18-prostatriensaeure-methylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

methyllithium
917-54-4

methyllithium

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.13E)-(8R.11R.12R.15S)-15-Hydroxy-9-oxo-11.19-dimethyl-5.13.18-prostatriensaeure-methylester

(5Z.13E)-(8R.11R.12R.15S)-15-Hydroxy-9-oxo-11.19-dimethyl-5.13.18-prostatriensaeure-methylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

methylmagnesium bromide
75-16-1

methylmagnesium bromide

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.10Z.13E)-(8R.12R.15RS)-15-Hydroxy-9-oxo-15.19-dimethyl-5.10.13.18-prostatetraensaeure-methylester

(5Z.10Z.13E)-(8R.12R.15RS)-15-Hydroxy-9-oxo-15.19-dimethyl-5.10.13.18-prostatetraensaeure-methylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.13E)-(8R.11R.12R.15S)-9-Oxo-11.15-dihydroxy-19-methyl-5.13.18-prostatriensaeuremethylester
66477-71-2

(5Z.13E)-(8R.11R.12R.15S)-9-Oxo-11.15-dihydroxy-19-methyl-5.13.18-prostatriensaeuremethylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(8R.9S.11R.12R.15R)-9.11.15-Trihydroxy-19-methyl-18-prostensaeuremethylester
66477-98-3

(8R.9S.11R.12R.15R)-9.11.15-Trihydroxy-19-methyl-18-prostensaeuremethylester

Conditions
ConditionsYield
Multistep reaction;
methyl 5-methyl-hex-4-enoate
35901-76-9

methyl 5-methyl-hex-4-enoate

(4-carboxybutyl)triphenylphosphonium bromide
17814-85-6

(4-carboxybutyl)triphenylphosphonium bromide

Methyltriphenylphosphonium bromide
1779-49-3

Methyltriphenylphosphonium bromide

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one
39746-01-5

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

(5Z.13E)-(8R.12R.15S)-15-Hydroxy-9-oxo-19-methyl-5.13.18-prostatriensaeure-methylester
66477-82-5

(5Z.13E)-(8R.12R.15S)-15-Hydroxy-9-oxo-19-methyl-5.13.18-prostatriensaeure-methylester

Conditions
ConditionsYield
Multistep reaction;

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