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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1-METHYLCYCLOBUTANAMINE

Cas:40571-47-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 40571-47-9 with best quality

Cas:40571-47-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

1-METHYL-CYCLOBUTYLAMINE CAS:40571-47-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

1-METHYL-CYCLOBUTYLAMINE CAS:40571-47-9

Cas:40571-47-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Cyclobutanamine, 1-methyl-

Cas:40571-47-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Cyclobutanamine, 1-methyl-

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Other

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

1-METHYL-CYCLOBUTYLAMINE HClAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

1-METHYL-CYCLOBUTYLAMINE HCl

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

40571-47-9

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

1-methyl-1-cyclobutanamine

Cas:40571-47-9

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

1-METHYLCYCLOBUTANAMINE CAS NO.40571-47-9

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of pl

Cyclobutanamine, 1-methyl-

Cas:40571-47-9

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

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Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.

High quality / commercialize;Stable production capacity.Appearance:actual character Storage:Temperature controlled NMT 30℃ Package:As customer request Application:Used for Synthesis API and Research Transportation:Follow the MSDS

1-methylcyclobutan-1-amine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zouping Mingxing Chemical Co.,Ltd.

high quality and competitive priceAppearance:colorless Storage:dry,cool Package:UN drum Application:intermediate Transportation:FOB or CIF

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chengdu Green Young Biopharmaceutical INC

pharmaceuticalintermediateAppearance:White Powder Storage:Cool Place Package:Bag/Drum Application:pharmaceutical intermediates Transportation:Air/Sea Port:Chengdu

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:1 Gram

FOB Price: $1.0 / 10.0

Type:Lab/Research institutions

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 1-Methyl-cyclobutylamine, CAS:40571-47-9 with the most competitive price and the best

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Nanjing Raymon Biotech Co., Ltd.

1-METHYL-CYCLOBUTYLAMINEAppearance:yellow to white solid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx.

1-METHYL-CYCLOBUTYLAMINE

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

40571-47-9

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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coolpharm Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar

1-METHYL-CYCLOBUTYLAMINE

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Other

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Beyond Pharmaceutical Co., Ltd

Used in medicine Application:Used in medicine

1-METHYL-CYCLOBUTYLAMINE HCl

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

1-Methyl-cyclobutylamine

Cas:40571-47-9

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

1-methylcyclobutanol
20117-47-9

1-methylcyclobutanol

potassium cyanide
151-50-8

potassium cyanide

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

Conditions
ConditionsYield
With dibutyl ether; sulfuric acid und Erhitzen des Reaktionsprodukts mit wss. HCl;
methylidenecyclobutane
1120-56-5

methylidenecyclobutane

sodium cyanide
143-33-9

sodium cyanide

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

Conditions
ConditionsYield
(i) AcOH, aq. H2SO4, (ii) aq. NaOH; Multistep reaction;
methylidenecyclobutane
1120-56-5

methylidenecyclobutane

acetonitrile
75-05-8

acetonitrile

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

Conditions
ConditionsYield
(i) AcOH, aq. H2SO4, (ii) aq. KOH, ethane-1,2-diol; Multistep reaction;
2-amino-4-methyl-thiophene-3-carboxylic acid ethyl ester
43088-42-2

2-amino-4-methyl-thiophene-3-carboxylic acid ethyl ester

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

ethyl 4-methyl-2-{[(1-methylcyclobutyl)carbamoyl]amino}thiophene-3-carboxylate

ethyl 4-methyl-2-{[(1-methylcyclobutyl)carbamoyl]amino}thiophene-3-carboxylate

Conditions
ConditionsYield
Stage #1: 2-amino-4-methyl-thiophene-3-carboxylic acid ethyl ester; 1,1'-carbonyldiimidazole With triethylamine In dichloromethane at 20℃; for 48h;
Stage #2: 1-methylcyclobutan-1-amine In dichloromethane at 20℃; for 1h;
97%
3,4-dichlorobenzenesulphonyl chloride
98-31-7

3,4-dichlorobenzenesulphonyl chloride

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

3,4-dichloro-N-(1-methylcyclobutyl)benzenesulfonamide

3,4-dichloro-N-(1-methylcyclobutyl)benzenesulfonamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 23℃; for 16h; Inert atmosphere;86%
4-phenyl-1,3-oxazole
20662-89-9

4-phenyl-1,3-oxazole

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

1-(1-methylcyclobutyl)-4-phenyl-1H-imidazole
1552273-92-3

1-(1-methylcyclobutyl)-4-phenyl-1H-imidazole

Conditions
ConditionsYield
With trifluoroacetic acid In 1,2-dichloro-benzene at 200℃; for 3h; Microwave irradiation;80%
3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylbenzoic acid
1382848-07-8

3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methylbenzoic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methyl-N-(1-methylcyclobutyl)benzamide
1382845-06-8

3-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-4-methyl-N-(1-methylcyclobutyl)benzamide

Conditions
ConditionsYield
With dmap; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 50℃; for 15h;78%
tert-butyl 4-((2-chloro-5-nitropyrimidin-4-yl)amino)piperidine-1-carboxylate
1124330-16-0

tert-butyl 4-((2-chloro-5-nitropyrimidin-4-yl)amino)piperidine-1-carboxylate

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

tert-butyl 4-((2-((1-methylcyclobutyl)amino)-5-nitropyrimidin-4-yl)amino)piperidine-1-carboxylate

tert-butyl 4-((2-((1-methylcyclobutyl)amino)-5-nitropyrimidin-4-yl)amino)piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium carbonate In N,N-dimethyl-formamide at 20℃; for 4h;61%
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

(1s,4s)-4-((2-chloro-5-nitropyrimidin-4-yl)amino)cyclohexane-1-carboxamide

(1s,4s)-4-((2-chloro-5-nitropyrimidin-4-yl)amino)cyclohexane-1-carboxamide

(1s,4s)-4-((2-((1-methylcyclobutyl)amino)-5-nitropyrimidin-4-yl)amino)cyclohexane-1-carboxamide

(1s,4s)-4-((2-((1-methylcyclobutyl)amino)-5-nitropyrimidin-4-yl)amino)cyclohexane-1-carboxamide

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 60℃; for 4h;51%
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

(2R)-2-{4-[(2-methylpentyl)oxy]phenyl}-2-[(2S)-2-phenylpropanamido]acetic acid

(2R)-2-{4-[(2-methylpentyl)oxy]phenyl}-2-[(2S)-2-phenylpropanamido]acetic acid

(2S)-N-((1R)-2-((1-methylcyclobutyl)amino)-1-(4-((2-methylpentyl)oxy)phenyl)-2-oxoethyl)-2-phenylpropanamide

(2S)-N-((1R)-2-((1-methylcyclobutyl)amino)-1-(4-((2-methylpentyl)oxy)phenyl)-2-oxoethyl)-2-phenylpropanamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;48%
5-phenyloxazole
1006-68-4

5-phenyloxazole

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

1-(1-methylcyclobutyl)-5-phenyl-1H-imidazole
1552273-91-2

1-(1-methylcyclobutyl)-5-phenyl-1H-imidazole

Conditions
ConditionsYield
With trifluoroacetic acid In 1,2-dichloro-benzene at 200℃; for 14h; Microwave irradiation;36%
cis {3-(3-chloro-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl}(morpholin-4-yl)methanone

cis {3-(3-chloro-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl}(morpholin-4-yl)methanone

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

cis (3-{3-[(1-methylcyclobutyl)amino]-1,2,4-oxadiazol-5-yl}-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl)(morpholin-4-yl)methanone

cis (3-{3-[(1-methylcyclobutyl)amino]-1,2,4-oxadiazol-5-yl}-5-[4-(trifluoromethyl)phenyl]piperidin-1-yl)(morpholin-4-yl)methanone

Conditions
ConditionsYield
In ethanol at 80 - 100℃; for 36h; Microwave irradiation;24%
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

2,4-dichloro-alpha(elhoxymethlene)-5-fluoro-beta-oxo-benzene propanoic acid ethyl ester
86483-52-5

2,4-dichloro-alpha(elhoxymethlene)-5-fluoro-beta-oxo-benzene propanoic acid ethyl ester

(Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-(1-methyl-cyclobutylamino)-acrylic acid ethyl ester
118539-53-0

(Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-(1-methyl-cyclobutylamino)-acrylic acid ethyl ester

Conditions
ConditionsYield
In ethanol Ambient temperature;
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

7-Chloro-6-fluoro-1-(1-methyl-cyclobutyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

7-Chloro-6-fluoro-1-(1-methyl-cyclobutyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethanol / Ambient temperature
2: NaH / dioxane / 1.) r.t., 30 min, 2.) reflux, 2.5 h
3: KOH / H2O / 1.5 h / Heating
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

7-Chloro-6-fluoro-1-(1-methyl-cyclobutyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

7-Chloro-6-fluoro-1-(1-methyl-cyclobutyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethanol / Ambient temperature
2: NaH / dioxane / 1.) r.t., 30 min, 2.) reflux, 2.5 h
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

6-Fluoro-1-(1-methyl-cyclobutyl)-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
118539-35-8

6-Fluoro-1-(1-methyl-cyclobutyl)-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ethanol / Ambient temperature
2: NaH / dioxane / 1.) r.t., 30 min, 2.) reflux, 2.5 h
3: KOH / H2O / 1.5 h / Heating
4: 30 percent / pyridine / 18 h / Heating
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

hexanal
66-25-1

hexanal

C11H21N

C11H21N

Conditions
ConditionsYield
In dichloromethane Dehydrating agent; Inert atmosphere;
With magnesium sulfate In dichloromethane for 1h;
4-amino-8-bromo-cinnoline-3-carboxylic acid sulfate

4-amino-8-bromo-cinnoline-3-carboxylic acid sulfate

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C14H15BrN4O
1309764-50-8

C14H15BrN4O

Conditions
ConditionsYield
Stage #1: 4-amino-8-bromo-cinnoline-3-carboxylic acid sulfate With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 0 - 20℃; for 2.25h;
Stage #2: 1-methylcyclobutan-1-amine With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃;
4-amino-8-bromo-cinnoline-3-carboxylic acid sulfate

4-amino-8-bromo-cinnoline-3-carboxylic acid sulfate

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C22H24N4O3
1309764-24-6

C22H24N4O3

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1,1'-carbonyldiimidazole / N,N-dimethyl-formamide / 2.25 h / 0 - 20 °C
1.2: 0 - 20 °C
2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,2-dimethoxyethane; ethanol; water / 90 °C
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C14H15BrN4O
1309764-50-8

C14H15BrN4O

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 20 °C
2.1: hydrogenchloride; acetic acid; sodium nitrite / water / 0 - 5 °C
2.2: -5 - 0 °C
3.1: aluminum (III) chloride / toluene / 70 - 90 °C
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C14H15BrN4O

C14H15BrN4O

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 20 °C
2.1: hydrogenchloride; acetic acid; sodium nitrite / water / 0 - 5 °C
2.2: -5 - 0 °C
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C22H24N4O3
1309764-24-6

C22H24N4O3

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 20 °C
2.1: hydrogenchloride; acetic acid; sodium nitrite / water / 0 - 5 °C
2.2: -5 - 0 °C
3.1: aluminum (III) chloride / toluene / 70 - 90 °C
4.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,2-dimethoxyethane; ethanol; water / 90 °C
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

C8H12N2O

C8H12N2O

Conditions
ConditionsYield
at 20℃;
1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C33H37N3O6*C2HF3O2

C33H37N3O6*C2HF3O2

Conditions
ConditionsYield
Stage #1: 1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid; 1-methylcyclobutan-1-amine With acetic acid In 1,2-dichloro-ethane at 20℃;
Stage #2: With sodium triacetoxyborohydride at 20℃;
Stage #3: With trifluoroacetic acid In methanol
100.9 mg
1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

4-hydroxy-9-methyl-10-(((1-methylcyclobutyl)amino)methyl)-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]indole-3-carboxylic acid hydrochloride

4-hydroxy-9-methyl-10-(((1-methylcyclobutyl)amino)methyl)-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]indole-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid / 1,2-dichloro-ethane / 1 h / 20 °C
2: chlorotriisopropylsilane; trifluoroacetic acid / 1 h / 65 °C
View Scheme
1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C33H37N3O6

C33H37N3O6

Conditions
ConditionsYield
Stage #1: 1-(2,4-dimethoxybenzyl)-10-formyl-4-hydroxy-9-methyl-2-oxo-1,2,5,6,7,9-hexahydropyrido[3',2':6,7]cyclohepta[1,2-f]-indole-3-carboxylic acid; 1-methylcyclobutan-1-amine With acetic acid In 1,2-dichloro-ethane at 20℃; for 1h;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane
1-(2,4-dimethoxvbenzvl)-10-formyl-4-hydroxy-9-methyl-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid

1-(2,4-dimethoxvbenzvl)-10-formyl-4-hydroxy-9-methyl-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

4-hydroxy-9-methyl-10-(((1-methylcyclobutyl)amino)methyl)-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid hydrochloride

4-hydroxy-9-methyl-10-(((1-methylcyclobutyl)amino)methyl)-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid / 1,2-dichloro-ethane / 1 h / 20 °C
2: chlorotriisopropylsilane; trifluoroacetic acid / 1 h / 65 °C
View Scheme
1-(2,4-dimethoxvbenzvl)-10-formyl-4-hydroxy-9-methyl-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid

1-(2,4-dimethoxvbenzvl)-10-formyl-4-hydroxy-9-methyl-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid

1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

C32H35N3O7

C32H35N3O7

Conditions
ConditionsYield
Stage #1: 1-(2,4-dimethoxvbenzvl)-10-formyl-4-hydroxy-9-methyl-2-oxo-2,5,6,9-tetrahydro-1H-pyrido[2',3':4,5]oxepino[3,2-f]indole-3-carboxylic acid; 1-methylcyclobutan-1-amine With acetic acid In 1,2-dichloro-ethane at 20℃; for 1h;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

hexanal
66-25-1

hexanal

N-[(5Z)-4-butyl-2-(1-methylcyclobutyl)-isothiazol-5(2H)-ylidene]-5-chloro-2-methoxybenzamide
1075241-57-4

N-[(5Z)-4-butyl-2-(1-methylcyclobutyl)-isothiazol-5(2H)-ylidene]-5-chloro-2-methoxybenzamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: magnesium sulfate / dichloromethane / 1 h
2.1: tetrahydrofuran / 1 h
2.2: 1 h / 20 °C
View Scheme
1-methyl-1-cyclobutylamine
40571-47-9

1-methyl-1-cyclobutylamine

N-((2S,3S)-3-amino-2-hydroxy-3-phenylpropyl)-3,4-dichloro-N-(1-methylcyclobutyl)benzenesulfonamide

N-((2S,3S)-3-amino-2-hydroxy-3-phenylpropyl)-3,4-dichloro-N-(1-methylcyclobutyl)benzenesulfonamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / 23 °C / Inert atmosphere
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / isopropyl alcohol / 16 h / Inert atmosphere; Heating
3: trimethylphosphane / water; tetrahydrofuran / 3 h / 23 °C / Inert atmosphere
View Scheme

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