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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(R)-METHYL 7-(3-HYDROXY-5-OXOCYCLOPENT-1-EN-1-YL)HEPTANOATE

Cas:41138-61-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(R)-7-(3-Hydroxy-5-oxo-1-cyclopenten-1-yl)-heptanoic acid methyl ester

Cas:41138-61-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE Synonyms: METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE;methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclo-pentene-1-;METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLO-P EN

41138-61-8 METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 41138-61-8 with best quality

Cas:41138-61-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Cyclopentene-1-heptanoicacid, 3-hydroxy-5-oxo-, methyl ester, (3R)- 41138-61-8

Cas:41138-61-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Cyclopentene-1-heptanoicacid, 3-hydroxy-5-oxo-, methyl ester, (3R)-

Cas:41138-61-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Cyclopentene-1-heptanoicacid, 3-hydroxy-5-oxo-, methyl ester, (3R)-

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

methyl 7-[3(R)-hydroxy-5-oxo-1-cyclopenten-1-yl]heptanoate 41138-61-8

Cas:41138-61-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLO-PENTENE-1-

Cas:41138-61-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

methyl (r)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate

Cas:41138-61-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-Cyclopentene-1-heptanoic acid, 3-hydroxy-5-oxo-, methyl ester, (3R)-

Cas:41138-61-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

methyl 7-[3(R)-hydroxy-5-oxo-1-cyclopenten-1-yl]heptanoate

Cas:41138-61-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 1-Cyclopentene-1-Heptanoic Acid,3-Hydroxy-5-Oxo-,Methyl Ester,(3R)- CAS No.:41138-61-8 Molecule Formula:C13H20O4 Molecule Weight:240.30 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise St

High Quality 1-Cyclopentene-1-Heptanoic Acid,3-Hydroxy-5-Oxo-,Methyl Ester,(3R)- on stock

Cas:41138-61-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD

CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD. founded in 1984, engages in pharmaceutical research, development, production, process design and technical consultation of synthetic and fermentation pharmaceutical products. The organizational s

41138-61-8 manufacturer/high quality/in stock

Cas:41138-61-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclo-pentene-1-

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1-Cyclopentene-1-heptanoicacid, 3-hydroxy-5-oxo-, methyl ester, (3R)-

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear light yellow liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

methyl (r)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate manufacture

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

41138-61-8

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate

Cas:41138-61-8

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

METHYL (R)-(+)-3-H

METHYL (R)-(+)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE

Cas:41138-61-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

Methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclopentene-1-heptanoate

Cas:41138-61-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Mingqi Chemical Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers. Our advantages:1, High quality with competitive price:1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer

High purity 99% methyl (R)-(+)-3-hydroxy-5-oxo-1-cyclo-pentene-1- factory in stock

Cas:41138-61-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methyl 7-<3(R)-(acetyloxy)-5-oxo-1-cyclopenten-1-yl>heptanoate
127126-27-6

methyl 7-<3(R)-(acetyloxy)-5-oxo-1-cyclopenten-1-yl>heptanoate

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
With guanidine nitrate98%
With guanidine nitrate In methanol at 0℃;
7-{5-oxo-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopent-1-en-1-yl}heptanoic acid methyl ester
60934-42-1

7-{5-oxo-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopent-1-en-1-yl}heptanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
With acetic acid In tetrahydrofuran; water for 24h; Ambient temperature;88%
Benzoic acid (R)-4-hydroxy-2-(6-methoxycarbonyl-hexyl)-3-oxo-cyclopent-1-enyl ester
41138-65-2

Benzoic acid (R)-4-hydroxy-2-(6-methoxycarbonyl-hexyl)-3-oxo-cyclopent-1-enyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
(i) Al, (ii) AcOH; Multistep reaction;
7-((R)-4-Hydroxy-2-isopropoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid methyl ester
53147-05-0

7-((R)-4-Hydroxy-2-isopropoxy-5-oxo-cyclopent-1-enyl)-heptanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
(i) Al, (ii) AcOH; Multistep reaction;
7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester
41138-69-6

7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran
7-[(R)-3-Oxo-5-(tetrahydro-pyran-2-yloxy)-cyclopent-1-enyl]-heptanoic acid methyl ester

7-[(R)-3-Oxo-5-(tetrahydro-pyran-2-yloxy)-cyclopent-1-enyl]-heptanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
With acetic acid
7-((S)-3-Methanesulfonyloxy-5-oxo-cyclopent-1-enyl)-heptanoic acid methyl ester
251659-67-3

7-((S)-3-Methanesulfonyloxy-5-oxo-cyclopent-1-enyl)-heptanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
With guanidine nitrate In methanol at 0℃; for 0.25h; Substitution; Mitsunobu inversion;
8-(furan-2-yl)-8-oxooctanoic acid methyl ester
38199-47-2

8-(furan-2-yl)-8-oxooctanoic acid methyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating
2: 46 percent / PPL
3: 98 percent / guanidine
View Scheme
suberic acid monomethyl ester
3946-32-5

suberic acid monomethyl ester

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating
2: 46 percent / PPL
3: 98 percent / guanidine
View Scheme
methyl 7-(3-hydroxy-5-oxocyclopent-1-en-1-yl)heptanoate
40098-26-8

methyl 7-(3-hydroxy-5-oxocyclopent-1-en-1-yl)heptanoate

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 46 percent / PPL
2: 98 percent / guanidine
View Scheme
Multi-step reaction with 2 steps
1: lipase (PPL)
2: quanidine / methanol / 0 °C
View Scheme
methyl 7-(2-hydroxy-5-oxocyclopent-3-enyl)heptanoate
98818-31-6

methyl 7-(2-hydroxy-5-oxocyclopent-3-enyl)heptanoate

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating
2: 46 percent / PPL
3: 98 percent / guanidine
View Scheme
methyl 8-(2-furyl)-8-hydroxy-octanoate
101650-79-7

methyl 8-(2-furyl)-8-hydroxy-octanoate

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aq. phosphate buffer; dioxane / 30 h / pH 8 / Heating
2: 46 percent / PPL
3: 98 percent / guanidine
View Scheme
methyl 7-<3(S)-(hydroxy)-5-oxo-1-cyclopenten-1-yl>heptanoate
42038-75-5

methyl 7-<3(S)-(hydroxy)-5-oxo-1-cyclopenten-1-yl>heptanoate

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Et3N / CH2Cl2 / -10 °C
2: guanidine / methanol / 0.25 h / 0 °C
View Scheme
C7H13IO2Zn
131392-85-3

C7H13IO2Zn

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1) CuCN / 2) THF, -78 deg C up to r.t.
2: n-Bu4NF / tetrahydrofuran
View Scheme
(3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-methoxy-2-methylene-cyclopentanone
117254-03-2

(3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-methoxy-2-methylene-cyclopentanone

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1) CuCN / 2) THF, -78 deg C up to r.t.
2: n-Bu4NF / tetrahydrofuran
View Scheme
2-(6-Methoxycarbonylhexyl)-cyclopentan-1,3,4-trion
41138-63-0

2-(6-Methoxycarbonylhexyl)-cyclopentan-1,3,4-trion

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (microbiological transformation)
2: Et3N
3: (i) Al, (ii) AcOH
View Scheme
Multi-step reaction with 3 steps
1: (microbiological transformation)
2: K2CO3
3: (i) Al, (ii) AcOH
View Scheme
2-(6'-carbomethoxyhexyl)-4(R)-hydroxy-cyclopentane-1,3-dione
41138-64-1

2-(6'-carbomethoxyhexyl)-4(R)-hydroxy-cyclopentane-1,3-dione

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Et3N
2: (i) Al, (ii) AcOH
View Scheme
Multi-step reaction with 2 steps
1: K2CO3
2: (i) Al, (ii) AcOH
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester
41138-69-6

7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide98%
With 1H-imidazole In N,N-dimethyl-formamide for 0.5h; Ambient temperature;95%
With 1H-imidazole; triethylamine In N,N-dimethyl-formamide84%
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester
41138-69-6

7-{3-[(tert-butyldimethylsilanyl)oxy]-5-oxocyclopent-1-en-1-yl}heptanoic acid methyl ester

Conditions
ConditionsYield
With 2,6-dimethylpyridine In dichloromethane at -78 - 20℃; for 15h; silylation;89%
With 2,6-dimethylpyridine In dichloromethane at -78 - 20℃; for 15.5h;
triethylsilyl chloride
994-30-9

triethylsilyl chloride

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

methyl-7-[5-oxo-3(R)-[(triethylsilyl)oxy]-1-cyclopenten-1yl]-heptanoate
118456-54-5

methyl-7-[5-oxo-3(R)-[(triethylsilyl)oxy]-1-cyclopenten-1yl]-heptanoate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; Etherification;88%
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

(-)-1-mercapto-2(S)-heptanol
82542-28-7

(-)-1-mercapto-2(S)-heptanol

A

5-(6-methoxycarbonylhexyl)-3-<2(S)-hydroxyheptylthio>-2-cyclopentenone
82542-34-5

5-(6-methoxycarbonylhexyl)-3-<2(S)-hydroxyheptylthio>-2-cyclopentenone

B

13,14-dihydro-13-thia-prostaglandin-E1 methylester
82542-32-3

13,14-dihydro-13-thia-prostaglandin-E1 methylester

C

/PBNDC003-1180/

/PBNDC003-1180/

Conditions
ConditionsYield
With triethylamine In methanol for 48h; Ambient temperature;A 7.9%
B 12.3%
C n/a
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

n-hexylmagnesium bromide
3761-92-0

n-hexylmagnesium bromide

(-)-methyl 7-[(1S,2R)-2-hexyl-5-oxocyclopent-3-enyl]heptanoate
947409-07-6

(-)-methyl 7-[(1S,2R)-2-hexyl-5-oxocyclopent-3-enyl]heptanoate

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at 0 - 30℃; for 36h;
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

(-)-methyl 7-[(1S,2R,5R)-2-hexyl-5-hydroxycyclopentyl]heptanoate

(-)-methyl 7-[(1S,2R,5R)-2-hexyl-5-hydroxycyclopentyl]heptanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran; diethyl ether / 36 h / 0 - 30 °C
2: L-selectride / tetrahydrofuran; 2-methyl-propan-2-ol / 1 h / -78 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

methyl 7-(5-but-3-enyl-2-hydroxy-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate
221629-33-0

methyl 7-(5-but-3-enyl-2-hydroxy-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-[(1R,2R,3R,5S)-2-But-3-enyl-3-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-cyclopentyl]-heptanoic acid methyl ester
221629-43-2

7-[(1R,2R,3R,5S)-2-But-3-enyl-3-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-cyclopentyl]-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

methyl 7-(2-hydroxy-5-(2-(2-oxiranyl)ethyl)-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate
221629-44-3

methyl 7-(2-hydroxy-5-(2-(2-oxiranyl)ethyl)-4-(1,1,2,2-tetramethyl-1-silapropoxy)cyclopentyl)heptanoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid methyl ester
1027145-33-0

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: triethylamine / benzene / 20 h / 0 - 20 °C
6.1: HF/pyridine / acetonitrile / 3 h / 0 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid methyl ester

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: triethylamine / benzene / 20 h / 0 - 20 °C
6.1: HF/pyridine / acetonitrile / 3 h / 0 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester
221629-35-2

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: triethylamine / benzene / 20 h / 0 - 20 °C
6.1: HF/pyridine / acetonitrile / 3 h / 0 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid

7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: triethylamine / benzene / 20 h / 0 - 20 °C
6.1: HF/pyridine / acetonitrile / 3 h / 0 °C
7.1: LiOH / tetrahydrofuran; H2O / 20 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acid

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: magnesium perchlorate / tetrahydrofuran / 3 h / Heating
6.1: HF/pyridine / acetonitrile / 5 h / 0 °C
7.1: 57 percent / LiOH / tetrahydrofuran; H2O / 20 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acid methyl ester
221629-38-5

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: magnesium perchlorate / tetrahydrofuran / 3 h / Heating
6.1: HF/pyridine / acetonitrile / 5 h / 0 °C
View Scheme
(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone
41138-61-8

(4R)-4-hydroxy-2-(6-methoxycarbonylhexyl)cyclopent-2-enone

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 89 percent / 2,6-lutidine / CH2Cl2 / 15 h / -78 - 20 °C
2.1: Mg; I2 / tetrahydrofuran / 3 h / Heating
2.2: 71 percent / CuBr*DMS / tetrahydrofuran / 2.25 h / -78 - 20 °C
3.1: 61 percent / NaBH4 / methanol / 25 h / -78 - -40 °C
4.1: 73 percent / m-CPBA; sodium bicarbonate / CH2Cl2 / 20 h / 20 °C
5.1: triethylamine / benzene / 20 h / 0 - 20 °C
6.1: HF/pyridine / acetonitrile / 3 h / 0 °C
7.1: LiOH / tetrahydrofuran; H2O / 20 °C
View Scheme

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