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Hangzhou Think Chemical Co. Ltd

2-Thioadenosine CAS No.:43157-50-2 Name: 2-Thioadenosine Synonyms: 2-Mercaptoadenosine Molecular Structure

High purity 2-Thioadenosine CAS No.:43157-50-2

Cas:43157-50-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 2-Thioadenosine 43157-50-2 Producer

Cas:43157-50-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

2-THIOADENOSINE

Cas:43157-50-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-THIOADENOSINE

Cas:43157-50-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-THIOADENOSINE

Cas:43157-50-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details

China Largest factory Manufacturer Supply 2-THIOADENOSINE CAS 43157-50-2

Cas:43157-50-2

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM-- 2-THIOADENOSINE

Cas:43157-50-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 43157-50-2 with competitive price

Cas:43157-50-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Adenosine,1,2-dihydro-2-thioxo-/ LIDE PHARMA- Factory supply / Best price

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Adenosine,1,2-dihydro-2-thioxo-

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

2-THIOADENOSINE 43157-50-2

Cas:43157-50-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

2-Thioadenosine cas 43157-50-2

Cas:43157-50-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2-THIOADENOSINE

Cas:43157-50-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

2,?3-?dihydro-?2-?thioxo-Adenosine

Cas:43157-50-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2-Thioadenosine

Cas:43157-50-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac

2-THIOADENOSINE

Cas:43157-50-2

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2,3-dihydro-2-thioxoAdenosine

Cas:43157-50-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Thioadenosine

Cas:43157-50-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Adenosine,1,2-dihydro-2-thioxo-

Cas:43157-50-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

2-Thioadenosine

Cas:43157-50-2

Min.Order:100 Gram

Negotiable

Type:Manufacturers

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Thioadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-Thioadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-Mercaptoadenosine

Cas:43157-50-2

Min.Order:1 Kilogram

Negotiable

Type:Other

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Senova Technology Company Limited

Good price, high purity, mature production technology, in stock, accept custom synthesis per customer's requirements Storage:in stock Package:As per Customer‘ requirements Application:Pharmaceutical API

2-Mercaptoadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:Off-white to light yellow solid powder Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Thioadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Thioadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Thioadenosine

Cas:43157-50-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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BOC Sciences

BOC Sciences is committed to supplying cost-effective products and services. We provide Cangrelor Impurity 6. an impurity of Cangrelor More information please visit: www.bocsci.com/cangrelor-impurity-6-cas-43157-50-2-item-468051.html Package:inqui

Cangrelor Impurity 6

Cas:43157-50-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

2-Thioadenosine

Cas:43157-50-2

Min.Order:0

Negotiable

Type:Manufacturers

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Synthetic route

carbon disulfide
75-15-0

carbon disulfide

5-amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamidoxime
57004-06-5

5-amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamidoxime

2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

Conditions
ConditionsYield
In tetrahydrofuran; methanol; dimethyl sulfoxide at 140 - 150℃; for 12h; Solvent;80%
In methanol; water at 120℃; for 5h; Autoclave;
With diammonium sulfide In methanol; water at 120℃; for 5h; Inert atmosphere; Sealed tube;30.73 g
carbon disulfide
75-15-0

carbon disulfide

2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

Conditions
ConditionsYield
With sodium hydroxide 1.) reflux, 2.) MeOH, H2O, 120 deg C, 5 h; Multistep reaction;
adenosine
58-61-7

adenosine

/PRBRB020--095/

/PRBRB020--095/

2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 45 percent / m-chloroperbenzoic acid / acetic acid / 48 h / Ambient temperature
2: 1.) 5N aq. NaOH / 1.) reflux, 2.) MeOH, H2O, 120 deg C, 5 h
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; water / 0.17 h / 140 °C
2: diammonium sulfide / methanol; water / 5 h / 120 °C / Inert atmosphere; Sealed tube
View Scheme
Stage #1: adenosine 1-oxide With sodium hydroxide
Stage #2: With carbon disulfide In methanol; water at 120℃;
Stage #1: adenosine 1-oxide With sodium hydroxide In water for 15h; Reflux;
Stage #2: With carbon disulfide In methanol; water at 120℃; for 5h; Autoclave;
adenosine
58-61-7

adenosine

2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

Conditions
ConditionsYield
Stage #1: adenosine With dihydrogen peroxide; acetic acid
Stage #2: With sodium hydroxide In water
Stage #3: With carbon disulfide In methanol; water at 120℃; for 5h; Autoclave;
Stage #1: adenosine With dihydrogen peroxide; acetic acid
Stage #2: With sodium hydroxide In water
Stage #3: With carbon disulfide In methanol; water at 120℃; for 5h; Autoclave;
Multi-step reaction with 3 steps
1: acetic acid; dihydrogen peroxide / 20 h / 50 °C
2: sodium hydroxide; water / 0.17 h / 140 °C
3: diammonium sulfide / methanol; water / 5 h / 120 °C / Inert atmosphere; Sealed tube
View Scheme
Multi-step reaction with 2 steps
1.1: 3-chloro-benzenecarboperoxoic acid / methanol / 38 h
2.1: sodium hydroxide / water / 15 h / Reflux
2.2: 5 h / 120 °C / Autoclave
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1-bromo-butane
109-65-9

1-bromo-butane

2-(n-butylthioether)adenosine
36965-96-5

2-(n-butylthioether)adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium hydroxide In methanol at 20℃; for 1h; deprotonation;
Stage #2: 1-bromo-butane In N,N-dimethyl-formamide at 20℃; for 4h; Alkylation;
92%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1,1,1-trifluoro-3-iodopropane
460-37-7

1,1,1-trifluoro-3-iodopropane

2-[(3,3,3-trifluoropropyl)thio]adenosine
163706-51-2

2-[(3,3,3-trifluoropropyl)thio]adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium dithionite In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: With sodium hydroxide In water; N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #3: 1,1,1-trifluoro-3-iodopropane In water; N,N-dimethyl-formamide at 20℃; Cooling with ice;
92%
In ethyl acetate at 20℃;84%
With sodium hydroxide In water
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

methyl iodide
74-88-4

methyl iodide

2-(methylthio)adenosine
4105-39-9

2-(methylthio)adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium dithionite In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: With sodium hydroxide In water; N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #3: methyl iodide In water; N,N-dimethyl-formamide at 20℃; Cooling with ice;
89%
With sodium hydroxide In methanol at 0℃; for 3h;
With sodium hydride In N,N-dimethyl-formamide at 20℃;
With sodium hydroxide In methanol; water at 0℃; for 3h;2.1 g
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

2-[(6-bromohexyl)thio]adenosine

2-[(6-bromohexyl)thio]adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine In methanol; sodium hydroxide at 20℃; for 1h;
Stage #2: 1 ,6-dibromohexane In N,N-dimethyl-formamide at 20℃; for 4h;
86%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

ethyl iodide
75-03-6

ethyl iodide

2-(Ethylthio)adenosine
31528-52-6

2-(Ethylthio)adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium dithionite In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: With sodium hydroxide In water; N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #3: ethyl iodide In water; N,N-dimethyl-formamide at 20℃; Cooling with ice;
81%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

8-(2-bromoethyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

8-(2-bromoethyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

S-[2-(4,4-difluoro-11,3,5,7-tetra-methyl-4-bora-3a,4a-diazas-indacen-8-yl)ethyl]-2-thioadenosine

S-[2-(4,4-difluoro-11,3,5,7-tetra-methyl-4-bora-3a,4a-diazas-indacen-8-yl)ethyl]-2-thioadenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium methylate In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: 8-(2-bromoethyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene In N,N-dimethyl-formamide at 20℃; for 16h;
79%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1-iodo-propane
107-08-4

1-iodo-propane

2-(propylthio)adenosine
31528-53-7

2-(propylthio)adenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium dithionite In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: With sodium hydroxide In water; N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #3: 1-iodo-propane In water; N,N-dimethyl-formamide at 20℃; Cooling with ice;
78%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

amyl iodide
628-17-1

amyl iodide

2-Amylthioadenosine
50823-24-0

2-Amylthioadenosine

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium dithionite In N,N-dimethyl-formamide for 0.5h; Inert atmosphere;
Stage #2: With sodium hydroxide In water; N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #3: amyl iodide In water; N,N-dimethyl-formamide at 20℃; Cooling with ice;
64%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

6-Bromo-1-hexene
2695-47-8

6-Bromo-1-hexene

2-(5-hexenylthio) adenosine
148527-85-9

2-(5-hexenylthio) adenosine

Conditions
ConditionsYield
With sodium hydroxide for 3h; Ambient temperature;55%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

2,2-dimethylpropyl bromide
630-17-1

2,2-dimethylpropyl bromide

(2R,3R,4S,5R)-2-[6-Amino-2-(2,2-dimethyl-propylsulfanyl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

(2R,3R,4S,5R)-2-[6-Amino-2-(2,2-dimethyl-propylsulfanyl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Conditions
ConditionsYield
Stage #1: 2-Mercaptoadenosine With sodium hydroxide In methanol at 20℃; for 1.5h;
Stage #2: 2,2-dimethylpropyl bromide In N,N-dimethyl-formamide at 80℃; for 48h; Further stages.;
52%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1,7-dibromoheptane
4549-31-9

1,7-dibromoheptane

2-<(7-bromoheptyl)thio>adenosine
151566-02-8

2-<(7-bromoheptyl)thio>adenosine

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 3h; Ambient temperature;33%
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1-bromocyclohexane
108-85-0

1-bromocyclohexane

2-(Cyclohexylthio)adenosine
43157-47-7

2-(Cyclohexylthio)adenosine

Conditions
ConditionsYield
With triethylamine 1.) DMF, 0.5 h, RT, 2.) DMF, 2.5 h; Multistep reaction;
Stage #1: 2-Mercaptoadenosine With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: 1-bromocyclohexane In ethanol; water at 20℃;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1-bromo-hexane
111-25-1

1-bromo-hexane

2-(Hexylthio)adenosine
50823-26-2

2-(Hexylthio)adenosine

Conditions
ConditionsYield
With triethylamine 1.) DMF, 0.5 h, RT, 2.) DMF, 2.5 h; Multistep reaction;
Stage #1: 2-Mercaptoadenosine With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: 1-bromo-hexane In ethanol; water at 20℃;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

7-bromo-heptanonitrile
20965-27-9

7-bromo-heptanonitrile

2-(6-cyanohexylthio)adenosine
148527-88-2

2-(6-cyanohexylthio)adenosine

Conditions
ConditionsYield
With triethylamine 1.) DMF, 0.5 h, RT, 2.) DMF, 2.5 h; Yield given. Multistep reaction;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

(4-nitrophenyl)ethyl bromide
5339-26-4

(4-nitrophenyl)ethyl bromide

2-(6-amino-2-(p-nitrophenylethyl)sulfanyl-7H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
151566-00-6

2-(6-amino-2-(p-nitrophenylethyl)sulfanyl-7H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Conditions
ConditionsYield
With triethylamine 1.) DMF, 0.5 h, RT, 2.) DMF, 2.5 h; Multistep reaction;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

1-phenyl-2-bromoethane
103-63-9

1-phenyl-2-bromoethane

2-<(phenylethyl)thio>adenosine
148527-86-0

2-<(phenylethyl)thio>adenosine

Conditions
ConditionsYield
With triethylamine 1.) DMF, 0.5 h, RT, 2.) DMF, 2.5 h; Multistep reaction;
Stage #1: 2-Mercaptoadenosine With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: 1-phenyl-2-bromoethane In ethanol; water at 20℃;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

3-chloro-1,1,1-trifluoropropane
460-35-5

3-chloro-1,1,1-trifluoropropane

2-[(3,3,3-trifluoropropyl)thio]adenosine
163706-51-2

2-[(3,3,3-trifluoropropyl)thio]adenosine

Conditions
ConditionsYield
With sodium hydride 1.) DMF, 2.) DMF, 36 h; Yield given; Multistep reaction;
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

2[(6-bromohexyl)thio]adenosine 5'-triphosphate

2[(6-bromohexyl)thio]adenosine 5'-triphosphate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: methanol; aq. NaOH / 1 h / 20 °C
1.2: 86 percent / dimethylformamide / 4 h / 20 °C
2.1: proton sponge; trimethyl phosphate; phosphorous oxychloride / 2.33 h / 0 °C
2.2: (Bu3NH(1+))2P2O7H2; Bu3N; tetraethylammonium bromide / dimethylformamide / 0.75 h / 20 °C
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

C11H14Cl2N5O4PS2
762287-83-2

C11H14Cl2N5O4PS2

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aq. NaOH / methanol / 3 h / 0 °C
2.1: proton sponge; pyridine / 0.25 h / 0 °C
2.2: PSCl3 / 0.25 h / 0 °C
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

(SP)-2-methylthioadenosine-5'-O-(1-thiotriphosphate) sodium salt

(SP)-2-methylthioadenosine-5'-O-(1-thiotriphosphate) sodium salt

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aq. NaOH / methanol / 3 h / 0 °C
2.1: proton sponge; pyridine / 0.25 h / 0 °C
2.2: PSCl3 / 0.25 h / 0 °C
3.1: H2P2O7(2-)*[(Bu3NH)(1+)]2; Bu3N / 0.05 h / 20 °C
3.2: aq. TEAB / 0.67 h / 20 °C
3.3: Sephadex-CM C-25
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

(RP)-2-methylthioadenosine-5'-O-(1-thiotriphosphate) sodium salt

(RP)-2-methylthioadenosine-5'-O-(1-thiotriphosphate) sodium salt

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aq. NaOH / methanol / 3 h / 0 °C
2.1: proton sponge; pyridine / 0.25 h / 0 °C
2.2: PSCl3 / 0.25 h / 0 °C
3.1: H2P2O7(2-)*[(Bu3NH)(1+)]2; Bu3N / 0.05 h / 20 °C
3.2: aq. TEAB / 0.67 h / 20 °C
3.3: Sephadex-CM C-25
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

C15H26N5O13P3S

C15H26N5O13P3S

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaOH / methanol / 1.5 h / 20 °C
1.2: 52 percent / dimethylformamide / 48 h / 80 °C
2.1: POCl3; PO(OCH3)3
2.2: (Bu3NH(1+))2H2P2O7(2-)
2.3: 71 percent / H2O
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

C14H20Cl2N5O5PS

C14H20Cl2N5O5PS

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 0.25 M aq. NaOH / methanol / 1 h / 20 °C
1.2: 92 percent / dimethylformamide / 4 h / 20 °C
2.1: proton sponge / various solvent(s) / 0.33 h / 0 °C
2.2: POCl3 / various solvent(s) / 2 h / 0 °C
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

2-(n-butylthioether)adenosine 5'-monophosphate

2-(n-butylthioether)adenosine 5'-monophosphate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 0.25 M aq. NaOH / methanol / 1 h / 20 °C
1.2: 92 percent / dimethylformamide / 4 h / 20 °C
2.1: proton sponge / various solvent(s) / 0.33 h / 0 °C
2.2: POCl3 / various solvent(s) / 2 h / 0 °C
3.1: 60 percent / (Bu3NH+)2P2O7H2; Bu3N / dimethylformamide / 0.02 h
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

2-BuS-ATP

2-BuS-ATP

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 0.25 M aq. NaOH / methanol / 1 h / 20 °C
1.2: 92 percent / dimethylformamide / 4 h / 20 °C
2.1: proton sponge / various solvent(s) / 0.33 h / 0 °C
2.2: POCl3 / various solvent(s) / 2 h / 0 °C
3.1: 30 percent / (Bu3NH+)2P2O7H2; Bu3N / dimethylformamide / 0.02 h
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

N6-(2-methoxyethyl)-2-(3,3,3-trifluoropropylthio)adenosine
163706-59-0

N6-(2-methoxyethyl)-2-(3,3,3-trifluoropropylthio)adenosine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) NaH / 1.) DMF, 2.) DMF, 36 h
2: 73 percent / AcONa / 7 h / 80 °C
3: NaH / dimethylformamide / 24 h / 60 °C
4: 0.1 M NaOH / methanol / 0.5 h / Heating
View Scheme
2-Mercaptoadenosine
43157-50-2

2-Mercaptoadenosine

(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
163706-58-9

(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) NaH / 1.) DMF, 2.) DMF, 36 h
2: 73 percent / AcONa / 7 h / 80 °C
3: NaH / dimethylformamide / 24 h / 60 °C
4: 0.1 M NaOH / methanol / 0.5 h / Heating
View Scheme
Multi-step reaction with 5 steps
1: ethyl acetate / 20 °C
2: triethylamine; dmap / acetonitrile / 0.5 h / 20 - 25 °C
3: copper(ll) bromide; isopentyl nitrite / tetrahydrofuran / 2 h / 30 - 50 °C
4: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
5: sodium hydroxide; methanol / 0.25 h / 5 °C / Cooling
View Scheme
Multi-step reaction with 5 steps
1: ethyl acetate / 20 °C
2: triethylamine; dmap / acetonitrile / 0.5 h / 20 - 25 °C
3: isopentyl nitrite; copper dichloride / tetrahydrofuran / 2 h / 30 - 50 °C
4: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
5: sodium hydroxide; methanol / 0.25 h / 5 °C / Cooling
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide / water
2: sodium acetate / 80 °C
3: sodium hydride / N,N-dimethyl-formamide
4: sodium hydroxide / methanol / Reflux
View Scheme

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