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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone supplier in China

Cas:43229-01-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone

Cas:43229-01-2

Min.Order:1

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-1-[3-nitro-4-(phenylmethoxy)-phenyl]-ethanone

Cas:43229-01-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone_

Cas:43229-01-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 43229-01-2 with competitive price

Cas:43229-01-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 43229-01-2 , 2-Bromo-4,6-dinitroaniline

Cas:43229-01-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name:2-Bromo-4'-Benzyloxy-3'-nitroacetophenone CAS: 43229-01-2 Appearance:White Powder Application: Used as an organic synthesis intermediate Appearance: White Powder Storage:Store in cool and dry place, away from sun ligh

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone CAS:43229-01-2

Cas:43229-01-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone 43229-01-2

Cas:43229-01-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone Chemical Properties Melting point 135-137 °C(Solv: ethanol (64-17-5)) Boiling point 465.2±35.0 °C(Predicted) density 1.517±0.06 g/cm3(Predicted) storage temp. und

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone.

Cas:43229-01-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone CAS:43229-01-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializin

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone CAS:43229-01-2

Cas:43229-01-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

(phenylmethoxy)phenyl]-ethanone

Cas:43229-01-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone

Cas:43229-01-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-bromo-4'-benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2-bromo-4'-benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Bromo-4’-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone

Cas:43229-01-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-bromo-4'-benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Dry,Seal and Cool place Package:25kg/drum, or as per your request. Application:Intermediates Transportation:by air or by sea or by Express Port:Shanghai;Ningbo

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-bromo-4'-benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone CAS No.: 43229-01-2 Molecule Formula:C15H12BrNO4 Molecule Weight:150.16 Purity: 99.0% Package: 25kg/drum Description:Off-white to light yellow powder Manufacture Standard

Lower Price 2-Bromo-4'-Benzyloxy-3'-Nitroacetophenone

Cas:43229-01-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Hunan Kaimir Biotechnology Co., Ltd. is a professional technology company specializing in the research and production of raw materials and intermediates. In 2017, it was recognized as a high-tech enterprise and a small technological innovation giant

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Metric Ton

Negotiable

Type:Other

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-bromo-4'-benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Senova Technology Company Limited

We have most reliable quality, competitive prices and full documents for this APIs 1. GMP WORKSHOP 2. DMF Application:pharmaceutical intermediate

2-Bromo-4'-Benzyloxy-3'-nitroacetophenone

Cas:43229-01-2

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-benzyloxy-3-nitroacetophenone
14347-05-8

4-benzyloxy-3-nitroacetophenone

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
With N,N,N-trimethylanilinium bromide In dichloromethane at 300℃; for 4h;98%
With phenyltrimethylammonium tribromide In methanol; dichloromethane at 20℃;97%
With bromine; acetic acid at 20℃;85%
4'-hydroxy-3'-nitroacetophenone
6322-56-1

4'-hydroxy-3'-nitroacetophenone

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: TBAI, K2CO3 / acetone
2: Br2 / CHCl3
View Scheme
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C
1.2: 3 h / 20 °C / Reflux
2.1: tetra-N-butylammonium tribromide / tetrahydrofuran; methanol / 4 h
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / water; acetone / 20 °C
1.2: 17 h / Reflux
2.1: bromine / acetic acid / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone; water / 60 °C
2: bromine / acetic acid / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate; sodium iodide / acetone / 66 h / Heating / reflux
2: phenyltrimethylammonium tribromide / tetrahydrofuran / 12 h / 20 °C
View Scheme
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: HNO3 / acetic acid / 0 °C
2: TBAI, K2CO3 / acetone
3: Br2 / CHCl3
View Scheme
Multi-step reaction with 3 steps
1: HNO3 / acetic acid / -0.1 °C
2: TBAI, K2CO3 / acetone
3: Br2 / CHCl3
View Scheme
benzyl bromide
100-39-0

benzyl bromide

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C
1.2: 3 h / 20 °C / Reflux
2.1: tetra-N-butylammonium tribromide / tetrahydrofuran; methanol / 4 h
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate; sodium iodide / acetone / 66 h / Heating / reflux
2: phenyltrimethylammonium tribromide / tetrahydrofuran / 12 h / 20 °C
View Scheme
benzyl chloride
100-44-7

benzyl chloride

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium carbonate / water; acetone / 20 °C
1.2: 17 h / Reflux
2.1: bromine / acetic acid / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone; water / 60 °C
2: bromine / acetic acid / 20 °C
View Scheme
4'-hydroxy-3'-nitroacetophenone
6322-56-1

4'-hydroxy-3'-nitroacetophenone

benzyl chloride
100-44-7

benzyl chloride

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate; N-benzyl-N,N,N-triethylammonium chloride / N,N-dimethyl-formamide / 4 h / 115 - 120 °C
2: 2,2'-azobis(isobutyronitrile); bromine / 4 h / 38 - 42 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol
188690-82-6

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol

Conditions
ConditionsYield
With dimethylsulfide borane complex; (3aS-cis)-(-)-3,3a,8,8a-tetrahydro-2H-indeno[1,2-d]oxazole-2-isopropylborane In tetrahydrofuran at -5 - 5℃; for 0.5h; Solvent; Temperature;99%
With oxazaborolidine from cis (1R,2S)-aminoindanol and trimethylboroxine; borane In tetrahydrofuran at -15℃;98%
With borane N,N-diethylaniline complex; (1R,2S)-1-Amino-2-indanol In tetrahydrofuran at 3 - 5℃; for 3.5h; optical yield given as %ee;95%
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol
193761-53-4

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol

Conditions
ConditionsYield
With oxazaborolidine from cis (1S,2R)-aminoindanol and trimethylboroxine; borane In tetrahydrofuran at -15℃;98%
With borane N,N-diethylaniline complex; (1S,2R)-1-amino-2-indanol In tetrahydrofuran at 0 - 5℃; for 2h;94%
With borane N,N-diethylaniline complex; (1S,2R)-1-amino-2-indanol In tetrahydrofuran at 0 - 5℃; for 2h;94%
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(+/-)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol
299964-35-5

(+/-)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran at 0 - 20℃;91%
With borane-THF In tetrahydrofuran at -20℃; Reduction;87%
With sodium tetrahydroborate In methanol
With sodium tetrahydroborate In tetrahydrofuran
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione
653572-66-8

3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione

1-(2-(4-(benzyloxy)-3-nitrophenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione

1-(2-(4-(benzyloxy)-3-nitrophenyl)-2-oxoethyl)-3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;74.1%
N-(tert-butoxycarbonyl)-4-aminobutanoic acid
57294-38-9

N-(tert-butoxycarbonyl)-4-aminobutanoic acid

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-(4-(benzyloxy)-3-nitrophenyl)-2-oxoethyl-4-(tert-butoxycarbonylamino)butanoate
1292299-09-2

2-(4-(benzyloxy)-3-nitrophenyl)-2-oxoethyl-4-(tert-butoxycarbonylamino)butanoate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃;67%
2-Amino-4-methylpyridine
695-34-1

2-Amino-4-methylpyridine

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-(4-benzyloxy-3-nitrophenyl)-7-methylimidazo<1,2-a>pyridine
141244-34-0

2-(4-benzyloxy-3-nitrophenyl)-7-methylimidazo<1,2-a>pyridine

Conditions
ConditionsYield
In acetonitrile for 7h; Heating;65%
5-methylpyrazin-2-amine
5521-58-4

5-methylpyrazin-2-amine

4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-(4-(benzyloxy)-3-nitrophenyl)-6-methylimidazo[1,2-a]pyrazine
1254709-33-5

2-(4-(benzyloxy)-3-nitrophenyl)-6-methylimidazo[1,2-a]pyrazine

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol Reflux;45%
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

A

(S)-4-benzyloxy-3-nitrostyrene oxide
188730-96-3

(S)-4-benzyloxy-3-nitrostyrene oxide

B

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol
193761-53-4

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol

C

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol
188690-82-6

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol

Conditions
ConditionsYield
With sodium formate; Triton X-100; (R,R)-TsDPEN; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer In water at 28℃; for 6h; Title compound not separated from byproducts;A 7%
B n/a
C n/a
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-(3-benzyloxy-4-nitrophenyl)oxirane
51582-41-3

2-(3-benzyloxy-4-nitrophenyl)oxirane

Conditions
ConditionsYield
With sodium hydroxide; sodium tetrahydroborate 1.) MeOH; Multistep reaction;
With sodium tetrahydroborate In methanol at 20℃; for 3h;
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

dibenzylamine
103-49-1

dibenzylamine

ω-(dibenzylamino)-4-benzyloxy-3-nitroacetophenone
173283-38-0

ω-(dibenzylamino)-4-benzyloxy-3-nitroacetophenone

Conditions
ConditionsYield
In benzene for 72h; Ambient temperature;
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

A

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol
193761-53-4

(S)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethanol

B

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol
188690-82-6

(R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol

Conditions
ConditionsYield
With boron trifluoride-tetrahydrofuran complex; (-)-(1R,2S)-1-amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene In tetrahydrofuran at 0℃; for 2h; Product distribution; other reag., other temp.;
With borane N,N-diethylaniline complex; (S)-Corey-Bakshi-Shibata oxazaborolidine In 1,2-dimethoxyethane; dichloromethane; water at 25 - 30℃; for 9h; Corey-Itsuno reduction; Inert atmosphere; optical yield given as %ee;
With borane N,N-diethylaniline complex; (1R,2S)-1-Amino-2-indanol In tetrahydrofuran at 25℃; for 1h; Concentration; enantioselective reaction;A n/a
B n/a
With dimethylsulfide borane complex; C9H10BNO In tetrahydrofuran at 25℃; for 2h; Temperature; Inert atmosphere; Cooling with ice; enantioselective reaction;A n/a
B n/a
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-benzyloxy-5-vinylaniline
876753-52-5

2-benzyloxy-5-vinylaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: NaBH4 / methanol / 3 h / 20 °C
2: HOAc / methanol
3: 10.6 g / triphenylphosphine; imidazole; iodine / toluene / 3 h / Heating
4: 79.5 percent / Fe; HOAc / methanol / 2 h / Heating
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

2-benzyloxy-5-vinylnitrobenzene
515152-69-9

2-benzyloxy-5-vinylnitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaBH4 / methanol / 3 h / 20 °C
2: HOAc / methanol
3: 10.6 g / triphenylphosphine; imidazole; iodine / toluene / 3 h / Heating
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

N-(2-(benzyloxy)-5-(oxiran-2-yl)phenyl)formamide

N-(2-(benzyloxy)-5-(oxiran-2-yl)phenyl)formamide

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: NaBH4 / methanol / 3 h / 20 °C
2: HOAc / methanol
3: 10.6 g / triphenylphosphine; imidazole; iodine / toluene / 3 h / Heating
4: 79.5 percent / Fe; HOAc / methanol / 2 h / Heating
5: acetic anhydride / CH2Cl2 / 1.5 h / 0 °C
6: 1.15 g / m-CPBA; NaHCO3 / CH2Cl2; H2O / 3 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / tetrahydrofuran
2: platinum on carbon; dimethylsulfide; hydrogen
3: acetic anhydride
4: potassium carbonate / tetrahydrofuran; methanol
View Scheme
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C
2: hydrogen; platinum on carbon; dimethylsulfide
3: acetic anhydride / 0 - 20 °C
4: potassium carbonate / methanol; tetrahydrofuran
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

N-(2-benzyloxy-5-vinylphenyl)formamide
876753-53-6

N-(2-benzyloxy-5-vinylphenyl)formamide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: NaBH4 / methanol / 3 h / 20 °C
2: HOAc / methanol
3: 10.6 g / triphenylphosphine; imidazole; iodine / toluene / 3 h / Heating
4: 79.5 percent / Fe; HOAc / methanol / 2 h / Heating
5: acetic anhydride / CH2Cl2 / 1.5 h / 0 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(4-benzyloxy-3-nitrophenyl)ethane-1,2-diol
876753-51-4

(4-benzyloxy-3-nitrophenyl)ethane-1,2-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / methanol / 3 h / 20 °C
2: HOAc / methanol
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(R)-1-(4-benzyloxy-3-nitrophenyl)oxirane
188730-94-1

(R)-1-(4-benzyloxy-3-nitrophenyl)oxirane

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 98 percent / oxazaborolidine from cis (1R,2S)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
View Scheme
Multi-step reaction with 2 steps
1: (-)-diisopinocamphenylborane chloride / dichloromethane / 20 - 30 °C / Inert atmosphere
2: potassium carbonate / tetrahydrofuran; methanol / 20 - 30 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(S)-4-benzyloxy-3-nitrostyrene oxide
188730-96-3

(S)-4-benzyloxy-3-nitrostyrene oxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 98 percent / oxazaborolidine from cis (1S,2R)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(R,R)-formoterol
73573-87-2

(R,R)-formoterol

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
4: dimethylsulfoxide / 87 h / 80 °C
5: neutral Al2O3 (activity III)
6: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
7: 69 percent / pyridine / 6.5 h / 60 °C
8: H2 / 10 percentPd/C / ethanol / 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
3.1: dimethylsulfoxide / 87 h / 80 °C
4.1: neutral Al2O3 (activity III)
5.1: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
6.1: 69 percent / pyridine / 6.5 h / 60 °C
7.1: H2 / 10 percentPd/C / ethanol / 20 °C
View Scheme
Multi-step reaction with 6 steps
1: 98 percent / oxazaborolidine from cis (1R,2S)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
3: 90 °C
4: H2 / PtO2
6: H2 / Pd-C / ethanol
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Acetic acid (R)-1-(4-benzyloxy-3-nitro-phenyl)-2-bromo-ethyl ester

Acetic acid (R)-1-(4-benzyloxy-3-nitro-phenyl)-2-bromo-ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

Acetic acid (S)-1-(4-benzyloxy-3-nitro-phenyl)-2-bromo-ethyl ester
299964-37-7

Acetic acid (S)-1-(4-benzyloxy-3-nitro-phenyl)-2-bromo-ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(R)-1-(3-Amino-4-benzyloxy-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol
299964-43-5

(R)-1-(3-Amino-4-benzyloxy-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
4: dimethylsulfoxide / 87 h / 80 °C
5: neutral Al2O3 (activity III)
6: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
View Scheme
Multi-step reaction with 5 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
3.1: dimethylsulfoxide / 87 h / 80 °C
4.1: neutral Al2O3 (activity III)
5.1: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol
245759-61-9

(R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
4: dimethylsulfoxide / 87 h / 80 °C
5: neutral Al2O3 (activity III)
View Scheme
Multi-step reaction with 4 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
3.1: dimethylsulfoxide / 87 h / 80 °C
4.1: neutral Al2O3 (activity III)
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

N-(2-Benzyloxy-5-{(R)-1-hydroxy-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide
408497-91-6

N-(2-Benzyloxy-5-{(R)-1-hydroxy-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
4: dimethylsulfoxide / 87 h / 80 °C
5: neutral Al2O3 (activity III)
6: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
7: 69 percent / pyridine / 6.5 h / 60 °C
View Scheme
Multi-step reaction with 6 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
3.1: dimethylsulfoxide / 87 h / 80 °C
4.1: neutral Al2O3 (activity III)
5.1: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
6.1: 69 percent / pyridine / 6.5 h / 60 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

[(R)-2-(4-Benzyloxy-3-nitro-phenyl)-2-trimethylsilanyloxy-ethyl]-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine

[(R)-2-(4-Benzyloxy-3-nitro-phenyl)-2-trimethylsilanyloxy-ethyl]-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C
2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C
3: K2CO3 / methanol / 2.5 h / 20 °C
4: dimethylsulfoxide / 87 h / 80 °C
View Scheme
Multi-step reaction with 3 steps
1.1: BH3*THF / tetrahydrofuran / -20 °C
1.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C
2.1: K2CO3 / methanol / 2.5 h / 20 °C
3.1: dimethylsulfoxide / 87 h / 80 °C
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(S,R)-Formoterol
67346-50-3

(S,R)-Formoterol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 98 percent / oxazaborolidine from cis (1S,2R)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
3: 90 °C
4: H2 / PtO2
6: H2 / Pd-C / ethanol
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide
67346-51-4

N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 98 percent / oxazaborolidine from cis (1R,2S)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
3: 90 °C
4: H2 / PtO2
6: H2 / Pd-C / ethanol
View Scheme
4-benzyloxy-3-nitrophenacyl bromide
43229-01-2

4-benzyloxy-3-nitrophenacyl bromide

(S,S)-formoterol

(S,S)-formoterol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 98 percent / oxazaborolidine from cis (1S,2R)-aminoindanol and trimethylboroxine, BH3 / tetrahydrofuran / -15 °C
2: 98 percent / aqueous sodium hydroxide / methanol / 0.5 h
3: 90 °C
4: H2 / PtO2
6: H2 / Pd-C / ethanol
View Scheme

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