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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

Cas:485-19-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Reticuline

Cas:485-19-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

shanghai Tauto Biotech Co., Ltd

17-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China

Reticuline

Cas:485-19-8

Min.Order:10 Milligram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract Reticuline HACCP manufacturer

Cas:485-19-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

7-Isoquinolinol,1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-,(1S)-

Cas:485-19-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:Pale Yellow Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Precursor of many aporphine and morphine-type alkalo

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:Herbal extr

Hangzhou Dingyan Chem Co., Ltd

Hangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in your re

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Reticuline R81890 5mg

Cas:485-19-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE:1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day2. The products are provided with COA, HPLC, NMR, quality assurance, pac

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-Methoxyphenyl)Methyl]-6-Methoxy-2-Methylisoquinolin-7-ol

Cas:485-19-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Hangzhou Fandachem Co.,Ltd

7-Isoquinolinol,1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-,(1S)-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transporta

Asure Biochem CO.,LTD.

*stable and better quality products*efficient and meticulous servicesAppearance:Powder Storage:Store in dry, cool and ventilated place Package:1kg/tin 5kg/tin 25kg/carton Application:Use in healthcare products. Use in food products. Use in Cosmetic p

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Reticuline

Cas:485-19-8

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Basic information Product Name: (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-m

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

Cas:485-19-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

485-19-8

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Shaanxi Cuicheng Biomedical Technology Co., Ltd. is located in Chuangzhi Industrial Park, Economic and Technological Development Zone, Hanzhong City, Shaanxi Province, China. It is a company specializing in natural medicines and high-throughput scree

Reticuline(485-19-8)

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Haiqiang Chemical Co.,Ltd.

Hangzhou Haiqiang Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quali

Reticuline

Cas:485-19-8

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Run-Biotech Co., Ltd.

1.We have rich experience in the development and production 2.Our factory is in Shanghai of China,We have convenient traffic conditions.3.We have advanced testing equipment and shipping line. Package:5g, 10g, 50g, 100g, 1kg Application:Pharmaceutical

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

High Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate

FT-0699770

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BioBioPha Co., Ltd

In Stock,Offering NMR, HPLC/TLC and COA Reports Application:For pharmaceutical, cosmetics, agrochemical and food industries research / Activity Screening / Standard / Reference compounds

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

NovaChemistry

High purity Application:Screening the references, analyzing the expectant ingredients

Reticuline

Cas:485-19-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
With borane-ammonia complex; recombinant monoamine oxidase D11 from Aspergillus niger; oxygen In aq. phosphate buffer; dimethyl sulfoxide at 37℃; for 48h; pH=7.7; Time; Resolution of racemate; Enzymatic reaction; enantioselective reaction;80%
1-(3'-benzyloxy-4'-methoxybenzyl)-7-benzyloxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
916-40-5

1-(3'-benzyloxy-4'-methoxybenzyl)-7-benzyloxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol; acetic acid under 2585.7 Torr; for 6h;0.026 g
isovanillin
621-59-0

isovanillin

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 75 percent / KOH / H2O / 5 h / Heating
2: 93 percent / NaBH4 / ethanol / 1.) room temperature, 18 h, 2.) reflux, 1 h
3: 96 percent / PBr3 / tetrahydrofuran / 1.5 h / 0 °C
4: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
5: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
6: K2CO3 / acetone / 14 h / Heating
7: lithium aluminum hydride / tetrahydrofuran / Heating
8: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
3-methoxy-4-(phenylmethoxy)benzaldehyde
2426-87-1

3-methoxy-4-(phenylmethoxy)benzaldehyde

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 73 percent / ammonium acetate / 1.5 h / Heating
2: 55 percent / lithium aluminum hydride / diethyl ether; tetrahydrofuran / 1.) reflux, 2 h, 2.) room temperature, overnight
3: formic acid / 48 h / 50 °C
4: 88 percent / ammonium sulfate / toluene / 48 h / Heating
5: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
6: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
7: K2CO3 / acetone / 14 h / Heating
8: lithium aluminum hydride / tetrahydrofuran / Heating
9: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine
22231-61-4

2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: formic acid / 48 h / 50 °C
2: 88 percent / ammonium sulfate / toluene / 48 h / Heating
3: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
4: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
5: K2CO3 / acetone / 14 h / Heating
6: lithium aluminum hydride / tetrahydrofuran / Heating
7: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
3-benzyloxy-4-methoxy-benzyl alcohol
1860-60-2

3-benzyloxy-4-methoxy-benzyl alcohol

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 96 percent / PBr3 / tetrahydrofuran / 1.5 h / 0 °C
2: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
3: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
4: K2CO3 / acetone / 14 h / Heating
5: lithium aluminum hydride / tetrahydrofuran / Heating
6: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
3-methoxy-4-benzyloxy-ω-nitrostyrolene
63909-38-6, 1860-56-6

3-methoxy-4-benzyloxy-ω-nitrostyrolene

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 55 percent / lithium aluminum hydride / diethyl ether; tetrahydrofuran / 1.) reflux, 2 h, 2.) room temperature, overnight
2: formic acid / 48 h / 50 °C
3: 88 percent / ammonium sulfate / toluene / 48 h / Heating
4: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
5: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
6: K2CO3 / acetone / 14 h / Heating
7: lithium aluminum hydride / tetrahydrofuran / Heating
8: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
4-methoxy-3-(benzyloxy)benzyl bromide
55667-12-4

4-methoxy-3-(benzyloxy)benzyl bromide

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
2: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
3: K2CO3 / acetone / 14 h / Heating
4: lithium aluminum hydride / tetrahydrofuran / Heating
5: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
vanillin
121-33-5

vanillin

KOH-solution

KOH-solution

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 88 percent / K2CO3 / ethanol
2: 73 percent / ammonium acetate / 1.5 h / Heating
3: 55 percent / lithium aluminum hydride / diethyl ether; tetrahydrofuran / 1.) reflux, 2 h, 2.) room temperature, overnight
4: formic acid / 48 h / 50 °C
5: 88 percent / ammonium sulfate / toluene / 48 h / Heating
6: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
7: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
8: K2CO3 / acetone / 14 h / Heating
9: lithium aluminum hydride / tetrahydrofuran / Heating
10: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
(S)-valinol-tert-butyl ether formamidine of 7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline
133320-18-0

(S)-valinol-tert-butyl ether formamidine of 7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
2: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
3: K2CO3 / acetone / 14 h / Heating
4: lithium aluminum hydride / tetrahydrofuran / Heating
5: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
1-(3'-benzyloxy-4'-methoxybenzyl)-7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline
19777-98-1

1-(3'-benzyloxy-4'-methoxybenzyl)-7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3 / acetone / 14 h / Heating
2: lithium aluminum hydride / tetrahydrofuran / Heating
3: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
(S)-7-Benzyloxy-1-(3-benzyloxy-4-methoxy-benzyl)-6-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester
23523-84-4, 56114-15-9

(S)-7-Benzyloxy-1-(3-benzyloxy-4-methoxy-benzyl)-6-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium aluminum hydride / tetrahydrofuran / Heating
2: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline
148776-16-3

7-benzyloxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 88 percent / ammonium sulfate / toluene / 48 h / Heating
2: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
3: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
4: K2CO3 / acetone / 14 h / Heating
5: lithium aluminum hydride / tetrahydrofuran / Heating
6: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
[1-[(S)-7-Benzyloxy-1-(3-benzyloxy-4-methoxy-benzyl)-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-meth-(E)-ylidene]-((S)-1-tert-butoxymethyl-2-methyl-propyl)-amine

[1-[(S)-7-Benzyloxy-1-(3-benzyloxy-4-methoxy-benzyl)-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-meth-(E)-ylidene]-((S)-1-tert-butoxymethyl-2-methyl-propyl)-amine

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
2: K2CO3 / acetone / 14 h / Heating
3: lithium aluminum hydride / tetrahydrofuran / Heating
4: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
3-benzyloxy-4-methoxybenzaldehyde
6346-05-0

3-benzyloxy-4-methoxybenzaldehyde

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 93 percent / NaBH4 / ethanol / 1.) room temperature, 18 h, 2.) reflux, 1 h
2: 96 percent / PBr3 / tetrahydrofuran / 1.5 h / 0 °C
3: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h
4: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature
5: K2CO3 / acetone / 14 h / Heating
6: lithium aluminum hydride / tetrahydrofuran / Heating
7: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr
View Scheme
Conditions
ConditionsYield
With ipecac alkaloid O-methyltransferase 3 Enzymatic reaction;
Conditions
ConditionsYield
With Escherichia coli monoamine oxidase MAO-N D11 Enzymatic reaction; enantioselective reaction;A n/a
B n/a
With recombinant monoamine oxidase D11 from Aspergillus niger In aq. phosphate buffer; dimethyl sulfoxide at 37℃; for 24h; pH=7.7; Resolution of racemate; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
formaldehyd
50-00-0

formaldehyd

N-benzoyl-norreticuline
13168-51-9

N-benzoyl-norreticuline

B

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
With sodium cyanoborohydride; zinc(II) chloride In methanol at 20℃; for 24h; Overall yield = 96 %; Overall yield = 32.5 mg;
dopamine
51-61-6

dopamine

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
With 4-morpholineethanesulfonic acid; ascorbate; isopropyl β-D-thiogalactopyranoside at 37℃; Enzymatic reaction;
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

(+)-reticuline N-oxide

(+)-reticuline N-oxide

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 2.5h;66%
5-Chloro-1-phenyltetrazole
14210-25-4

5-Chloro-1-phenyltetrazole

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

7,11-O,O-bis(1-phenyl-1H-tetrazol-5-yl)reticuline

7,11-O,O-bis(1-phenyl-1H-tetrazol-5-yl)reticuline

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In acetonitrile for 24h; Reflux;63%
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

B

(S)-(-)-pallidine
25650-75-3

(S)-(-)-pallidine

C

S-(-)-coreximine
483-45-4

S-(-)-coreximine

Conditions
ConditionsYield
With phosphate buffer; (S)-2-[3]pyridyl-pyrrolidine-1-carboxylic acid amide; NADPH; magnesium chloride at 37℃; for 2h; rat liver microsomes;A 7.5%
B 5.2%
C 21.1%
D 7.9%
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

(S)-(+)-<2',6',8-3H3>reticuline
74080-69-6

(S)-(+)-<2',6',8-3H3>reticuline

Conditions
ConditionsYield
With tritium oxide; potassium tert-butylate at 100℃; for 110h; sealed tube;
With tritium oxide; potassium tert-butylate at 100℃; for 110h;
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
enzymatic reaction with berberine bridge enzyme;
berberine bridge enzyme Mechanism; stereochemistry of enzymatic berberine bridge formation;
With glycine-NaOH buffer; berberine bridge-forming enzyme In water at 30℃; for 1h; Mechanism; further benzylisoquinolines; tritium labelling (-N-CT3) experiments;
With berberine bridge enzyme; tris hydrochloride at 37℃; for 2h; pH=8.8; Enzymatic reaction;
With berberine bridge enzyme Enzymatic reaction;
acetic anhydride
108-24-7

acetic anhydride

(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

L-Reticulin-diacetat
14199-49-6

L-Reticulin-diacetat

Conditions
ConditionsYield
With pyridine at 20℃;
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

(1S,2S)-reticuline Nα-oxide

(1S,2S)-reticuline Nα-oxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / 20 °C
2: m-CPBA / CH2Cl2
3: 1.6 mg / aq. NH4OH / methanol / 20 °C
View Scheme
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

C23H27NO7

C23H27NO7

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / 20 °C
2: m-CPBA / CH2Cl2
View Scheme
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

(1S,2R)-reticuline Nβ-oxide

(1S,2R)-reticuline Nβ-oxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / 20 °C
2: m-CPBA / CH2Cl2
3: 1.3 mg / aq. NH4OH / methanol / 20 °C
View Scheme
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

columbamine
3621-36-1

columbamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: enzymatic reaction with berberine bridge enzyme
2: S-adenosyl-L-methionine / enzymatic reaction with (S)-scoulerine-9-O-methyltransferase
3: enzymatic reaction with (S)-tetrahydroprotoberberine oxidase
View Scheme
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: enzymatic reaction with berberine bridge enzyme
2: S-adenosyl-L-methionine / enzymatic reaction with (S)-scoulerine-9-O-methyltransferase
View Scheme
(+)-(S)-reticuline
485-19-8

(+)-(S)-reticuline

Nandinine
572-76-9

Nandinine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: recombinant berberine bridge enzyme; recombinant CYP719A13 enzyme from Argemone mexicana; recombinant CYP719A14 enzyme from Argemone mexicana; recombinant cytochrome P450 reductase from Eschscholzia californica; NADPH / 1 h / 30 °C / pH 8 / Enzymatic reaction
2: recombinant CYP719A13 enzyme from Argemone mexicana; NADPH / 0.17 h / 30 °C / pH 8 / Enzymatic reaction
View Scheme

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