Products

Refine

Country

Business Type

Certificate

Display

Greenutra Resource Inc

Appearance:White crystalline powder Storage:Store in a cool dry place, avoiding sunlight directly Package:Food grade multiplayer polyethylene bags, 25kg in one type cardboard drum Application:Nutritional health products and food additives Tr

Cytisine powder

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $35.0 / 150.0

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Cytisine with high purity

Cas:485-35-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Superiority pioneerbiotech is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best q

Cytisine

Cas:485-35-8

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Top quality Cytisine

Cas:485-35-8

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Cytisine Cas 485-35-8 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to yellowish powder Storage:Cool dry place Package:100g,1kg/foil bag

High quality Cytisine Cas 485-35-8 with best price

Cas:485-35-8

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

Company profile Xi’an Quanao Biotech Co., Ltd. with 10 years experience in plant extract filed. Focus on the research, production and sale of Plant and Animal extract, Medical intermediate, complete coverage six industries.

Pure Nature 98% Cytisine Powder From Thermopsis lanceolate Extract cas no 485-35-8

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $14.0 / 42.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cytisine

Cas:485-35-8

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Cytisine 485-35-8 ISO Producer

Cas:485-35-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality CYTISINE

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Cytisine Manufacturer/High quality/Best price/In stock

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(-)-Cytisine

Cas:485-35-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Cytisine Alias:Cytisine plantagenone uroline English Name:Cytisine Molecular formula:C11H14N2O Molecular weight:190.24 Packaging Specification: 25kg/drum high purity 99%min stock Hubei DiBo Chemical Co., Ltd. was founded in 2009, is

Cytisine material/powder /CAS:485-35-8

Cas:485-35-8

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM CYTISINE

Cas:485-35-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Sophora flavescens extract 98% cytosine powder CAS 485-35-8

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 485-35-8 with competitive price

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Henan Sinotech Import&Export Corporation

Product Name Cytisine Appearance White to Light Yellow Powder Odor &Taste Characteristic Identificat

Cytisine CAS: 485-35-8

Cas:485-35-8

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White or light yellow powder Storage:R.T Package:5kg/drum Application:Pharm raw material Transportation:Express/Sea/Air Port:Any port in China

99% Cytisine powder CAS 485-35-8

Cas:485-35-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed containers

Natural Cytisine 98% 99% CAS 485-35-8

Cas:485-35-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1. English Name: Cytisine/Sparteine/Baptitoxine 2. Variety: Thermopsis Lanceolata Extract 3. Testing Method: HPLC 4. Appearance: white Powder 5. Specification:10-98% 6. CAS No.:485-35-8 7.Molecular Formula: C11H14N2O

Fatory Cytisine 98% Gorse Extract Top Supplier

Cas:485-35-8

Min.Order:10 Pound

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Cytisine

Cas:485-35-8

Min.Order:5 Gram

FOB Price: $40.0 / 65.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

CYTISINE CAS:485-35-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, ste

CYTISINE CAS:485-35-8

Cas:485-35-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Cytisine

Cas:485-35-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers

Pure Natural gorse extract Cytisine 99%

Cas:485-35-8

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Cytisine

Cas:485-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Cytisine

Cas:485-35-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:as your requirement Application:Only used for research and development. Not as a drug, household or other USES. Transportat

CYTISINE

Cas:485-35-8

Min.Order:1 Gram

FOB Price: $1.0 / 10.0

Type:Lab/Research institutions

inquiry

Purestar Chem Enterprise Co.,Ltd

Cytisine English name: Cytisine Chinese alias:wild indigo alkali roxian ketone alkaloid Molecular formula: C11H14N2O Molecular quality: 190.24 CAS: 485-35-8. Product content: 98% HPLC Product traits: oblique prism yellow-white powder Produc

Cytisine

Cas:485-35-8

Min.Order:1 Kilogram

FOB Price: $5.0 / 8.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cytisine

Cas:485-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(6R,7R,9R)-(-)-N-benzyloxycarbonyl-cytisine
667940-15-0

(6R,7R,9R)-(-)-N-benzyloxycarbonyl-cytisine

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran for 3h; Heating;78%
N-nosyl-(−)-cytisine

N-nosyl-(−)-cytisine

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
With potassium carbonate; thiophenol In N,N-dimethyl-formamide; acetonitrile at 45℃; for 0.5h;96%
(1R,9R)-11-tert-butoxycarbonyl-7,11-diazatricyclo[7.3.1.02,7]tridec-2,4-dien-6,10-dione

(1R,9R)-11-tert-butoxycarbonyl-7,11-diazatricyclo[7.3.1.02,7]tridec-2,4-dien-6,10-dione

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Stage #1: (1R,9R)-11-tert-butoxycarbonyl-7,11-diazatricyclo[7.3.1.02,7]tridec-2,4-dien-6,10-dione With methanol; sodium tetrahydroborate at 0 - 20℃; for 2h;
Stage #2: With triethylsilane; boron trifluoride diethyl etherate In dichloromethane at -78 - 20℃; for 15h;
79%
(3S,5R)-(+)-3-acetoxymethyl-5-formyl-1-piperidine-1-carbvoxylic acid benzyl ester
206554-22-5

(3S,5R)-(+)-3-acetoxymethyl-5-formyl-1-piperidine-1-carbvoxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: (-)-B-methoxydiisopinocampheylborane / diethyl ether / 1.25 h / -78 - 20 °C
1.2: diethyl ether / -78 - 20 °C / Acid hydrolysis
1.3: 76 percent / aq. NaOH; aq. H2O2 / 3 h / Heating
2.1: 99 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
3.1: 87 percent / NaN3 / dimethylformamide / 2 h / 80 °C
4.1: Ph3P / tetrahydrofuran
4.2: 66 percent / H2O
5.1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
6.1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
7.1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
8.1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
9.1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
10.1: 50 percent / DDQ / dioxane / 4 h / 110 °C
11.1: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R)-3-acetoxymethyl-5-hydroxymethylpiperidine-1-carboxylic acid benzyl ester
206761-38-8

(3S,5R)-3-acetoxymethyl-5-hydroxymethylpiperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1.1: (-)-B-methoxydiisopinocampheylborane / diethyl ether / 1.25 h / -78 - 20 °C
1.2: diethyl ether / -78 - 20 °C / Acid hydrolysis
1.3: 76 percent / aq. NaOH; aq. H2O2 / 3 h / Heating
2.1: 99 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
3.1: 87 percent / NaN3 / dimethylformamide / 2 h / 80 °C
4.1: Ph3P / tetrahydrofuran
4.2: 66 percent / H2O
5.1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
6.1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
7.1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
8.1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
9.1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
10.1: 50 percent / DDQ / dioxane / 4 h / 110 °C
11.1: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R,1'S)-(-)-3-acetoxymethyl-5-(1'-hydroxybut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester
667940-16-1

(3S,5R,1'S)-(-)-3-acetoxymethyl-5-(1'-hydroxybut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: 99 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
2.1: 87 percent / NaN3 / dimethylformamide / 2 h / 80 °C
3.1: Ph3P / tetrahydrofuran
3.2: 66 percent / H2O
4.1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
5.1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
6.1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
7.1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
8.1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
9.1: 50 percent / DDQ / dioxane / 4 h / 110 °C
10.1: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R,1'R)-(-)-3-acetoxymethyl-5-(1'-azidobut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester
667940-11-6

(3S,5R,1'R)-(-)-3-acetoxymethyl-5-(1'-azidobut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: Ph3P / tetrahydrofuran
1.2: 66 percent / H2O
2.1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
3.1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
4.1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
5.1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
6.1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
7.1: 50 percent / DDQ / dioxane / 4 h / 110 °C
8.1: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R)-3-Acetoxymethyl-5-((R)-1-amino-but-3-enyl)-piperidine-1-carboxylic acid benzyl ester
667940-18-3

(3S,5R)-3-Acetoxymethyl-5-((R)-1-amino-but-3-enyl)-piperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
2: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
3: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
4: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
5: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
6: 50 percent / DDQ / dioxane / 4 h / 110 °C
7: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R,1'S)-(+)-3-acetoxymethyl-5-(1'-methanesulfonyloxybut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester
667940-10-5

(3S,5R,1'S)-(+)-3-acetoxymethyl-5-(1'-methanesulfonyloxybut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: 87 percent / NaN3 / dimethylformamide / 2 h / 80 °C
2.1: Ph3P / tetrahydrofuran
2.2: 66 percent / H2O
3.1: 89 percent / Et3N; DMAP / CH2Cl2 / 4.5 h / 0 - 20 °C
4.1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
5.1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
6.1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
7.1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
8.1: 50 percent / DDQ / dioxane / 4 h / 110 °C
9.1: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(3S,5R,1'R)-(+)-3-acetoxymethyl-5-(1'-acryloylaminobut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester
667940-08-1

(3S,5R,1'R)-(+)-3-acetoxymethyl-5-(1'-acryloylaminobut-3'-enyl)-1-piperidine-1-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 79 percent / Cl2Ru(CHPh)(PCy3)2 / CH2Cl2 / 12 h / Heating
2: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
3: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
4: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
5: 50 percent / DDQ / dioxane / 4 h / 110 °C
6: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one
485-35-8, 15191-27-2, 55821-72-2

1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
With camphor-10-sulfonic acid
(6R,7R,9R)-(+)-N-benzyloxycarbonyl-5,6-dihydro-cytisine
667940-14-9

(6R,7R,9R)-(+)-N-benzyloxycarbonyl-5,6-dihydro-cytisine

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 50 percent / DDQ / dioxane / 4 h / 110 °C
2: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(2R,3'R,5'S)-(+)-5-hydroxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester
667940-12-7

(2R,3'R,5'S)-(+)-5-hydroxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
2: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
3: 50 percent / DDQ / dioxane / 4 h / 110 °C
4: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(2R,3'R,5'S)-(+)-5-acetoxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester
667940-07-0

(2R,3'R,5'S)-(+)-5-acetoxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 98 percent / NaOH / tetrahydrofuran / 2 h / 20 °C
2: 67 percent / Et3N; DMAP / CH2Cl2 / 1.5 h / 20 °C
3: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
4: 50 percent / DDQ / dioxane / 4 h / 110 °C
5: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(2R,3'R,5'S)-(+)-5-methanesulfonyloxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester
667940-13-8

(2R,3'R,5'S)-(+)-5-methanesulfonyloxymethyl-6-oxo-1,2,3,6,3',4',5',6'-octahydro-2'H-[2,3']-bipyridinyl-1'-carboxylic acid benzyl ester

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / NaH / tetrahydrofuran / 0 - 20 °C
2: 50 percent / DDQ / dioxane / 4 h / 110 °C
3: 78 percent / HCl / tetrahydrofuran / 3 h / Heating
View Scheme
(1R,5R)-6-methyl-3,7-diazabicyclo[3.3.1]non-6-en-2-one

(1R,5R)-6-methyl-3,7-diazabicyclo[3.3.1]non-6-en-2-one

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine; dmap / dichloromethane / 20 h
2.1: triethylamine / tetrahydrofuran / 5 h / 20 °C
3.1: methanol; sodium tetrahydroborate / 2 h / 0 - 20 °C
3.2: 15 h / -78 - 20 °C
View Scheme
(1R,5R)-3-tert-butoxycarbonyl-6-methyl-3,7-diazabicyclo[3.3.1]non-6-en-2-one

(1R,5R)-3-tert-butoxycarbonyl-6-methyl-3,7-diazabicyclo[3.3.1]non-6-en-2-one

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / tetrahydrofuran / 5 h / 20 °C
2.1: methanol; sodium tetrahydroborate / 2 h / 0 - 20 °C
2.2: 15 h / -78 - 20 °C
View Scheme
methyl 5-(6-bromopyridin-2-yl)-1-tosylpiperidine-3-carboxylate

methyl 5-(6-bromopyridin-2-yl)-1-tosylpiperidine-3-carboxylate

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C
2.1: triethylamine / dichloromethane / 1 h / 0 °C
3.1: chloroform / 6.5 h / Reflux
3.2: 9 h / 23 °C
4.1: thiophenol; potassium carbonate / acetonitrile; N,N-dimethyl-formamide / 0.5 h / 45 °C
View Scheme
(5-(6-bromopyridin-2-yl)-1-tosylpiperidin-3-yl)methanol

(5-(6-bromopyridin-2-yl)-1-tosylpiperidin-3-yl)methanol

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 1 h / 0 °C
2.1: chloroform / 6.5 h / Reflux
2.2: 9 h / 23 °C
3.1: thiophenol; potassium carbonate / acetonitrile; N,N-dimethyl-formamide / 0.5 h / 45 °C
View Scheme
C19H23BrN2O5S2

C19H23BrN2O5S2

cytisine
485-35-8

cytisine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: chloroform / 6.5 h / Reflux
1.2: 9 h / 23 °C
2.1: thiophenol; potassium carbonate / acetonitrile; N,N-dimethyl-formamide / 0.5 h / 45 °C
View Scheme
cytisine
485-35-8

cytisine

Nitrosocytisine
19634-60-7

Nitrosocytisine

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite at 20℃; for 288h; Nitrosation;100%
With potassiuim nitrosodisulfonate; hydroxylamine hydrochloride; sodium carbonate In pyridine for 0.25h;91%
acetic anhydride
108-24-7

acetic anhydride

cytisine
485-35-8

cytisine

(-)-(1R,5S)-N-acetyl-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one
6018-52-6

(-)-(1R,5S)-N-acetyl-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido-[1,2-a][1,5]diazocin-8-one

Conditions
ConditionsYield
With dmap In pyridine at 20℃; for 12h; Acetylation;100%
88.4%
1-adamantyl isocyanate
4411-25-0

1-adamantyl isocyanate

cytisine
485-35-8

cytisine

N-1-adamantylcytisine-12-carbamide

N-1-adamantylcytisine-12-carbamide

Conditions
ConditionsYield
In benzene at 80℃;100%
1-adamantylisothiocyanate
4411-26-1

1-adamantylisothiocyanate

cytisine
485-35-8

cytisine

N-1-adamantylcytisine-12-thiocarbamide
1621257-20-2

N-1-adamantylcytisine-12-thiocarbamide

Conditions
ConditionsYield
In benzene at 80℃;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

cytisine
485-35-8

cytisine

8-oxo-1,5,6,8-tetrahydro-2H,4H-1,5-methano-pyrido[1,2-a][1,5]diazocine-3-carboxylic acid tert-butyl ester [N-tboccytisine]
207390-62-3

8-oxo-1,5,6,8-tetrahydro-2H,4H-1,5-methano-pyrido[1,2-a][1,5]diazocine-3-carboxylic acid tert-butyl ester [N-tboccytisine]

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran; water at 20℃; for 48h;99%
With sodium carbonate In tetrahydrofuran at 20℃; for 24h;96%
With sodium carbonate In tetrahydrofuran; water for 72h;93%
benzyl bromide
100-39-0

benzyl bromide

cytisine
485-35-8

cytisine

(1R,9S)-11-benzyl-7,11-diazatricyclo[7.3.1.0]trideca-2,4-dien-6-one
78867-61-5, 109667-42-7

(1R,9S)-11-benzyl-7,11-diazatricyclo[7.3.1.0]trideca-2,4-dien-6-one

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 20h; Reflux;99%
With potassium carbonate In acetonitrile for 5h; Heating;94%
With potassium carbonate In acetonitrile for 5h; Reflux; Inert atmosphere;94%
With sodium carbonate In dichloromethane; water for 4h; Heating;77%
thiourea
17356-08-0

thiourea

cytisine
485-35-8

cytisine

N-cytisine-12-thiocarbamide
1401073-44-6

N-cytisine-12-thiocarbamide

Conditions
ConditionsYield
In pentan-1-ol at 137℃;98%
allylisocyanate
1476-23-9

allylisocyanate

cytisine
485-35-8

cytisine

N-allylcytisine-11-carbamide
449797-68-6

N-allylcytisine-11-carbamide

Conditions
ConditionsYield
In benzene at 20℃;98%
phenyl isocyanate
103-71-9

phenyl isocyanate

cytisine
485-35-8

cytisine

N-phenylcytisine-11-carbamide
40705-13-3

N-phenylcytisine-11-carbamide

Conditions
ConditionsYield
In benzene at 20℃;98%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

cytisine
485-35-8

cytisine

N,N'-[methylene-bis(4,1-phenylene)]dicytisinecarboxamide
1620659-65-5

N,N'-[methylene-bis(4,1-phenylene)]dicytisinecarboxamide

Conditions
ConditionsYield
In benzene at 80℃;98%
2-(4-phenoxybutyl)oxirane
85234-59-9

2-(4-phenoxybutyl)oxirane

cytisine
485-35-8

cytisine

(1R,2'ζ,5S)-3-(2-hydroxy-6-phenoxyhexyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

(1R,2'ζ,5S)-3-(2-hydroxy-6-phenoxyhexyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

Conditions
ConditionsYield
In methanol at 90℃; for 8h;98%
formaldehyd
50-00-0

formaldehyd

Ethyl isocyanoacetate
2999-46-4

Ethyl isocyanoacetate

cytisine
485-35-8

cytisine

ethyl 2-(5-(((1R,5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)methyl)-1H-tetrazol-1-yl)acetate

ethyl 2-(5-(((1R,5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)methyl)-1H-tetrazol-1-yl)acetate

Conditions
ConditionsYield
With trimethylsilylazide In methanol at 20℃; for 24h; Ugi Condensation;98%
formaldehyd
50-00-0

formaldehyd

cytisine
485-35-8

cytisine

methyl 3-isocyanopropanoate

methyl 3-isocyanopropanoate

methyl 3-(5-(((1R,5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)methyl)-1H-tetrazol-1-yl)propanoate

methyl 3-(5-(((1R,5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)methyl)-1H-tetrazol-1-yl)propanoate

Conditions
ConditionsYield
With trimethylsilylazide In methanol at 20℃; for 24h; Ugi Condensation;98%
Methoxyacetyl chloride
38870-89-2

Methoxyacetyl chloride

cytisine
485-35-8

cytisine

(1R,5S)-N-(2-methoxyacetyl)-1,2,3,4,5,6-hexahydro-1,5-methanopyrido[1,2-a]diazocin-8-one
881853-39-0

(1R,5S)-N-(2-methoxyacetyl)-1,2,3,4,5,6-hexahydro-1,5-methanopyrido[1,2-a]diazocin-8-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 18h;97%
3,5-dichlorobenzoyl chloride
2905-62-6

3,5-dichlorobenzoyl chloride

cytisine
485-35-8

cytisine

(1R,5S)-3-(3,5-Dichloro-benzoyl)-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one

(1R,5S)-3-(3,5-Dichloro-benzoyl)-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one

Conditions
ConditionsYield
With triethylamine In acetone Acylation; Heating;96%
propionyl chloride
79-03-8

propionyl chloride

cytisine
485-35-8

cytisine

(1R,5S)-3-propionyl-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
474116-07-9

(1R,5S)-3-propionyl-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;96%
With triethylamine In dichloromethane at 0 - 22℃; for 3h;12.3 g
N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

cytisine
485-35-8

cytisine

cytisino-N-allylthiocarbamide
945421-04-5

cytisino-N-allylthiocarbamide

Conditions
ConditionsYield
In benzene at 35 - 40℃;96%
1,1-bis(diethylphosphono)ethylene
37465-31-9

1,1-bis(diethylphosphono)ethylene

cytisine
485-35-8

cytisine

C13H20N2O7P2*BrH

C13H20N2O7P2*BrH

Conditions
ConditionsYield
In chloroform at 20℃; for 72h;96%
3-(4-chlorophenyl)-2-methyl-7-(4-(oxiran-2-yl)butoxy)-4H-chromen-4-one

3-(4-chlorophenyl)-2-methyl-7-(4-(oxiran-2-yl)butoxy)-4H-chromen-4-one

cytisine
485-35-8

cytisine

(1R,2’ζ,5S)-3-(6-((3-(4-chlorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)-2-hydroxyhexyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

(1R,2’ζ,5S)-3-(6-((3-(4-chlorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)-2-hydroxyhexyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

Conditions
ConditionsYield
In ethanol at 90℃; for 20h;96%
In ethanol at 90℃; for 20h;96%
cytisine
485-35-8

cytisine

formic acid ethyl ester
109-94-4

formic acid ethyl ester

(1R,5S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(4H)-carbaldehyde
53007-06-0

(1R,5S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocine-3(4H)-carbaldehyde

Conditions
ConditionsYield
With triethylamine for 19h; Reflux;96%
tert-butylisonitrile
119072-55-8, 7188-38-7

tert-butylisonitrile

pentan-3-one
96-22-0

pentan-3-one

cytisine
485-35-8

cytisine

(1R,5S)-3-(3-(1-(tert-butyl)-1H-tetrazol-5-yl)pentan-3-yl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

(1R,5S)-3-(3-(1-(tert-butyl)-1H-tetrazol-5-yl)pentan-3-yl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one

Conditions
ConditionsYield
With trimethylsilylazide In methanol at 20℃; for 24h; Ugi Condensation;96%
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View