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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4,4'-Diphenylmethane Diisocyanate (Mdi) supplier in China

Cas:101-68-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

Methylenediphenyl 4,4'-Diisocyanate

Cas:101-68-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4,4'-Diphenylmethane Diisocyanate (Mdi)

Cas:101-68-8

Min.Order:1

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4,4'-Diphenylmethane diisocyanate

Cas:101-68-8

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

4,4'-Diphenylmethane diisocyanate Manufacturer/High quality/Best price/In stock

Cas:101-68-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

4,4'-Diphenylmethane diisocyanate,101-68-8

Cas:101-68-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Lonwin Chemical Group Limited

4,4'-Diphenylmethane diisocyanate CAS:101-68-8 Specification Melting point 38-44 °C Boiling point 392 °C density 1.19 Fp 196 °C storage temp. Refrigerator s

Factory supply 4,4'-Diphenylmethane diisocyanate

Cas:101-68-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Triumph International Development Limilted

Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:As customer request Port:Qingda

4,4'-Diphenylmethane diisocyanate 101-68-8

Cas:101-68-8

Min.Order:1 Kilogram

FOB Price: $16.0 / 20.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4,4'-Diphenylmethane diisocyanate

Cas:101-68-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzene,1,1'-methylenebis[4-isocyanato-

Cas:101-68-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 4,4'-Diphenylmethane Diisocyanate (Mdi)

Cas:101-68-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermed

Benzene,1,1'-methylenebis[4-isocyanato-

Cas:101-68-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4,4'-Diphenylmethane diisocyanate

Cas:101-68-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

4,4'-Diphenylmethane diisocyanateCAS NO.: 101-68-8

Cas:101-68-8

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methylenedi-p-phenyl diisocyanate

Cas:101-68-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methylene diphenyl diisocyanate

Cas:101-68-8

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Diphenylmethane diisocyanate (mixture of 2,4'-and 4,4'-)

Cas:101-68-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Benzene,1,1'-methylenebis[4-isocyanato-

Cas:101-68-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4,4'-Diphenylmethane Diisocyanate (Mdi)

Cas:101-68-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 101-68-8 with competitive price

Cas:101-68-8

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzene,1,1'-methylenebis[4-isocyanato-

Cas:101-68-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

4,4'-Diphenylmethane diisocyanate (MDI)

Cas:101-68-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

High quality MDI for sale,99% Methylene diphenyl diisocyanate for PU Foam , CAS no 101-68-8 with best price !!! . Application:High quality MDI for sale,99% Methylene diphenyl diisocyanate for PU Foam , CAS no 101-68-8 with best price !!! .

Hunan Longxianng Runhui Trading Co.,Ltd

High quality MDI for sale,99% Methylene diphenyl diisocyanate for PU Foam , CAS no 101-68-8 with best price !!! .Appearance:brown liquid Storage:Keep in dry and ventilated place Package:200KG/DRUM or according to customer's requiement Application:MDI

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

we produce and sell good chemicals around the world.Appearance:white power Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:SEA OR AIR Port:China Main Po

Methylene diphenyl diisocyanate

Cas:101-68-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Methylenedi-p-phenyl diisocyanate 101-68-8

Cas:101-68-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#101-68-8;CAT#A800436

Cas:101-68-8

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

4,4'-Diphenylmethane diisocyanate Basic information

101-68-8 C15H10N2O2 4,4'-Diphenylmethane diisocyanate

Cas:101-68-8

Min.Order:5 Gram

Negotiable

Type:Trading Company

inquiry

WEIFANG XINGANGHENGRUI IMPORT AND EXPORT CO LTD

Q1: Are you a manufacturer A: Yes, We are the manufacturer invovled in this line for more than 10 years. Q2: Do you have stock A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some

Synthetic route

4,4'-methylenediphenyl dicarbamate

4,4'-methylenediphenyl dicarbamate

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With copper In para-xylene at 220℃; under 2625.26 Torr; for 2h; Reagent/catalyst; Pressure; Temperature; Solvent;98.7%
dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane
7450-63-7

dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With zinc diacetate; 1-((ethoxycarbonyl)methyl)-3-methylimidazolium tetrafluoroborate In neat (no solvent) at 25 - 230℃; for 0.25h; Catalytic behavior; Mechanism; Reagent/catalyst; Solvent; Inert atmosphere;96%
N-trimethyl-butyltetrafluoroboric acid; zinc(II) oxide at 200 - 240℃; under 48.7549 Torr; for 2.66667h;84%
With montmorillonite K-10 In decalin at 190℃; for 24h;40%
With boron trichloride; triethylamine In benzene for 0.5h; Heating;87 % Chromat.
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
at 130℃; for 2h;92%
In ethyl acetate for 4h; Heating;90%
(methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester
10097-16-2

(methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With isocyanurate for 200h; Reflux;92%
With boron trichloride; triethylamine In benzene for 0.5h; Heating;93 % Chromat.
N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid diphenyl ester
101-65-5

N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid diphenyl ester

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With DURANATE TPA-100 In 1,2-dichloro-benzene at 250℃; under 6000.6 Torr; for 200h; Inert atmosphere;86%
at 130 - 220℃; under 3.75038 - 450.045 Torr; for 240h; Product distribution / selectivity;82.3%
at 230℃; under 9.75098 Torr; Product distribution / selectivity; Industry scale;
phosgene
75-44-5

phosgene

4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With hydrogenchloride; N-benzyl-N,N,N-triethylammonium chloride In water; 1,2-dichloro-benzene at 40 - 160℃; for 5h; pH=2 - 3;85.8%
With N,N-dimethyl-aniline; toluene
With 1,2-dichloro-benzene
In chlorobenzene at 90℃; under 7500.75 Torr; Inert atmosphere;
4,4'-methylenediphenylene biscarbamate

4,4'-methylenediphenylene biscarbamate

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With benzoyl chloride In dodecane at 210℃; for 2.5h; Solvent;85%
4,4'-methylenediphenyldicarbamayl fluoride

4,4'-methylenediphenyldicarbamayl fluoride

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
at 160℃; for 0.5h; Glovebox;81%
dibutyl diphenyl methane-4,4’-dicarbamate
47636-24-8

dibutyl diphenyl methane-4,4’-dicarbamate

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
tetrabutylphosphonium bis(trifluoromethanesulfonyl)imide at 180 - 240℃; under 48.7549 Torr; for 2.66667h;79%
C25H36N4O2
216142-79-9

C25H36N4O2

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In 1,2-dichloro-benzene at 185℃; under 760.051 Torr; for 1.5h; Product distribution / selectivity;79%
phosgene
75-44-5

phosgene

polyamines

polyamines

2,4'-diaminodiphenylmethane
1208-52-2

2,4'-diaminodiphenylmethane

2,2'-methylenedianiline
6582-52-1

2,2'-methylenedianiline

4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

A

polyisocyanates

polyisocyanates

B

4,4′-methylenebis(phenylisocyanate)
2536-05-2

4,4′-methylenebis(phenylisocyanate)

C

2,4'-diisocyanatodiphenylmethane
5873-54-1

2,4'-diisocyanatodiphenylmethane

D

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In chlorobenzene at 0℃; Product distribution / selectivity;A 35%
B 0.2%
C 5.5%
D 44.1%
phosgene
75-44-5

phosgene

4,4'-Di(trimethylsilylamino)-diphenylmethan
1767-02-8

4,4'-Di(trimethylsilylamino)-diphenylmethan

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In toluene
phosgene
75-44-5

phosgene

Dimethylsilanyl-{4-[4-(1,1,3,3-tetramethyl-disilazan-2-yl)-benzyl]-phenyl}-amine
57586-53-5

Dimethylsilanyl-{4-[4-(1,1,3,3-tetramethyl-disilazan-2-yl)-benzyl]-phenyl}-amine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid dipropyl ester
60483-67-2

N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid dipropyl ester

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With boron trichloride; triethylamine In benzene for 0.5h; Heating;88 % Chromat.
C15H10N2O2*C8H9NO2

C15H10N2O2*C8H9NO2

A

N-phenyl methyl carbamate
2603-10-3

N-phenyl methyl carbamate

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 24.9℃; Equilibrium constant;
C15H10N2O2*C9H11NO2

C15H10N2O2*C9H11NO2

A

methyl p-tolylcarbamate
5602-96-0

methyl p-tolylcarbamate

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 24.9℃; Equilibrium constant;
C15H10N2O2*C10H13NO2

C15H10N2O2*C10H13NO2

A

carbamic acid, phenyl-, 1-methylethyl ester
122-42-9

carbamic acid, phenyl-, 1-methylethyl ester

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 24.9℃; Equilibrium constant;
C15H10N2O2*C11H15NO2

C15H10N2O2*C11H15NO2

A

methyl N-(2,4,6-trimethylphenyl)carbamate
81517-97-7

methyl N-(2,4,6-trimethylphenyl)carbamate

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 24.9℃; Equilibrium constant;
C15H10N2O2*C9H10ClNO3

C15H10N2O2*C9H10ClNO3

A

methyl N-(4-chloro-3-metyhoxyphenyl)carbamate
154244-57-2

methyl N-(4-chloro-3-metyhoxyphenyl)carbamate

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In diethylene glycol dimethyl ether at 24.9℃; Equilibrium constant;
phosgene
75-44-5

phosgene

formaldehyd
50-00-0

formaldehyd

A

polymeric MDI; mixture of

polymeric MDI; mixture of

B

4,4′-methylenebis(phenylisocyanate)
2536-05-2

4,4′-methylenebis(phenylisocyanate)

C

2,4'-diisocyanatodiphenylmethane
5873-54-1

2,4'-diisocyanatodiphenylmethane

D

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
Stage #1: formaldehyd; aniline; hydrogenchloride In water at 40 - 100℃; for 13h; Heating / reflux;
Stage #2: phosgene In chlorobenzene at 100 - 210℃; for 2h; Product distribution / selectivity;
dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane
7450-63-7

dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane

A

[4-(4-Isocyanato-benzyl)-phenyl]-carbamic acid methyl ester
37144-79-9

[4-(4-Isocyanato-benzyl)-phenyl]-carbamic acid methyl ester

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With montmorillonite K-10 In decalin at 190℃; for 5h;
4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2SO4, (NH4)2SO4
2: toluene
View Scheme
2,2'-diisocyanatodiphenylmethane; 2,4'-diisocyanatodiphenylmethane; 4,4'-diisocyanatodiphenylmethane; mixture of

2,2'-diisocyanatodiphenylmethane; 2,4'-diisocyanatodiphenylmethane; 4,4'-diisocyanatodiphenylmethane; mixture of

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
Purification / work up;
phosgene
75-44-5

phosgene

2,4'-diaminodiphenylmethane
1208-52-2

2,4'-diaminodiphenylmethane

2,2'-methylenedianiline
6582-52-1

2,2'-methylenedianiline

4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

A

4,4′-methylenebis(phenylisocyanate)
2536-05-2

4,4′-methylenebis(phenylisocyanate)

B

2,4'-diisocyanatodiphenylmethane
5873-54-1

2,4'-diisocyanatodiphenylmethane

C

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In chlorobenzene at 0℃; Product distribution / selectivity; Heating / reflux;
In chlorobenzene at 0℃; Product distribution / selectivity; Industry scale;
N,N'-(4,4'-methanediyl-diphenyl)-biscarbamic acid bis(2,4-di-tert-amylphenyl) ester
1027096-23-6

N,N'-(4,4'-methanediyl-diphenyl)-biscarbamic acid bis(2,4-di-tert-amylphenyl) ester

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
at 210℃; under 0.750075 Torr; for 11h; Product distribution / selectivity;
at 260℃; under 11.2511 Torr; Industry scale;
N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid diisopentyl ester
102894-34-8

N,N'-(4,4'-methanediyl-di-phenyl)-bis-carbamic acid diisopentyl ester

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
With 2,4-di-tert-amylphenol; dibutyltin dilaurate at 220℃; under 9.75098 Torr; for 15h; Product distribution / selectivity;
With dibutyltin dilaurate at 270℃; under 9.75098 Torr; Industry scale;
dibutyltin dilaurate at 170 - 270℃; under 9.75098 Torr;
phosgene
75-44-5

phosgene

2,2'-methylenedianiline
6582-52-1

2,2'-methylenedianiline

4,4'-diamino diphenyl methane
101-77-9

4,4'-diamino diphenyl methane

A

4,4′-methylenebis(phenylisocyanate)
2536-05-2

4,4′-methylenebis(phenylisocyanate)

B

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In chlorobenzene Heating;
aniline
62-53-3

aniline

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 4-t-amylphenol / 80 °C / Industry scale
2: 200 °C / 60.01 Torr / Industry scale
3: sulfuric acid / nitrobenzene / 10 h / 100 °C / Industry scale
4: 260 °C / 11.25 Torr / Industry scale
View Scheme
Multi-step reaction with 4 steps
1: 4-t-amylphenol / 80 °C / Industry scale
2: 190 °C / 375.04 Torr / Industry scale
3: dibutyltin dilaurate / 250 °C / 375.04 Torr / Industry scale
4: 260 °C / 11.25 Torr / Industry scale
View Scheme
Multi-step reaction with 4 steps
1: 4-t-amylphenol / 80 °C / Industry scale
2: 220 °C / 187.52 Torr / Industry scale
3: sulfuric acid / nitrobenzene / 15 h / 100 °C / Industry scale
4: 260 °C / 7.5 Torr / Industry scale
View Scheme
methanol
67-56-1

methanol

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane
7450-63-7

dimethyl 4,4'-methylenebis(1,4-phenylene)diurethane

Conditions
ConditionsYield
for 4h; Heating;100%
for 3h;96%
ethanol
64-17-5

ethanol

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

(methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester
10097-16-2

(methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester

Conditions
ConditionsYield
With MoCl2O2(dmf)2 In dichloromethane at 20℃; for 1h; Inert atmosphere;100%
In tetrahydrofuran at 20℃; for 2h;94%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

tert-butyl alcohol
75-65-0

tert-butyl alcohol

O,O'-di-tert-butyl 4,4'-methylenebis(4,1-phenylene)dicarbamate
59255-81-1

O,O'-di-tert-butyl 4,4'-methylenebis(4,1-phenylene)dicarbamate

Conditions
ConditionsYield
With MoCl2O2(dmf)2 In dichloromethane at 20℃; for 1h; Inert atmosphere;100%
In toluene at 85℃; for 3h; Inert atmosphere;96%
In toluene at 85℃; for 3h; Inert atmosphere;96%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

butan-1-ol
71-36-3

butan-1-ol

dibutyl diphenyl methane-4,4’-dicarbamate
47636-24-8

dibutyl diphenyl methane-4,4’-dicarbamate

Conditions
ConditionsYield
for 4h; Heating;100%
In tetrahydrofuran at 20℃; for 2h;84%
N,N-dibutyl amino-2 ethanol
102-81-8

N,N-dibutyl amino-2 ethanol

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

4,4'-methylenebis(phenyl-carbamic acid 2-[bis-butyl-amino]-ethyl ester)
939402-96-7

4,4'-methylenebis(phenyl-carbamic acid 2-[bis-butyl-amino]-ethyl ester)

Conditions
ConditionsYield
In tetrahydrofuran for 12h; Heating / reflux;99%
(4R,5R)-1,3-dioxolane-4,5-dicarbohydrazide
1380440-07-2

(4R,5R)-1,3-dioxolane-4,5-dicarbohydrazide

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

(4R,5R,25R,26R)-tetra-(hydrazinecarboxamide)cyclophane
1447810-13-0

(4R,5R,25R,26R)-tetra-(hydrazinecarboxamide)cyclophane

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 24h;99%
(2R,3R)-1,4-dioxaspiro[4.5]decane-2,3-dicarbohydrazide
1374018-88-8

(2R,3R)-1,4-dioxaspiro[4.5]decane-2,3-dicarbohydrazide

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

(4R,5R,25R,26R)-tetra-(hydrazinecarboxamide)cyclophane
1447810-17-4

(4R,5R,25R,26R)-tetra-(hydrazinecarboxamide)cyclophane

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 24h;99%
N-acetylglycine
543-24-8

N-acetylglycine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C21H24N4O4

C21H24N4O4

Conditions
ConditionsYield
With triethylamine In chloroform; toluene for 2h; Reflux;99%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

diphenylmethane-4,4'-bis-carbamic acid chloride
10016-36-1

diphenylmethane-4,4'-bis-carbamic acid chloride

Conditions
ConditionsYield
With hydrogenchloride In chlorobenzene at 30℃;99%
1,1-dimethylhydrazine
57-14-7

1,1-dimethylhydrazine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

4,4'-bis(diimethylamino-urea)diphenylmethane
85095-61-0

4,4'-bis(diimethylamino-urea)diphenylmethane

Conditions
ConditionsYield
In benzene 0-5 deg C, then 1 h at 20-25 deg C;98%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

12-[4-(12-hydroxydodecyloxy)phenoxy]dodecan-1-ol
209588-75-0

12-[4-(12-hydroxydodecyloxy)phenoxy]dodecan-1-ol

Polymer, Mw 107000; Monomer(s): 1,4-bis(12-hydroxydodecyloxy)benzene; 1,1-methylenebis[4-isocyanatobenzene]

Polymer, Mw 107000; Monomer(s): 1,4-bis(12-hydroxydodecyloxy)benzene; 1,1-methylenebis[4-isocyanatobenzene]

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃; for 20h; Polymerization;98%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

cytisine
485-35-8

cytisine

N,N'-[methylene-bis(4,1-phenylene)]dicytisinecarboxamide
1620659-65-5

N,N'-[methylene-bis(4,1-phenylene)]dicytisinecarboxamide

Conditions
ConditionsYield
In benzene at 80℃;98%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

ethylhydrazine carboxylate
4114-31-2

ethylhydrazine carboxylate

diethyl 2,2'-[methylenebis(4,1-phenyleneiminocarbonyl)]dihydrazinecarboxylate

diethyl 2,2'-[methylenebis(4,1-phenyleneiminocarbonyl)]dihydrazinecarboxylate

Conditions
ConditionsYield
In toluene at 20 - 90℃; for 4h; Inert atmosphere;98%
In toluene at 0℃; for 3.66667h; Inert atmosphere; Reflux;96%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C15H12Br2N2O2

C15H12Br2N2O2

Conditions
ConditionsYield
With hydrogen bromide In chlorobenzene at 30℃;98%
C2F5SO2N(CH3)CH2CH2OH

C2F5SO2N(CH3)CH2CH2OH

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C20H18F5N3O5S
856220-63-8

C20H18F5N3O5S

Conditions
ConditionsYield
dibutyltin(II) dilaurate In n-heptane at 50℃; for 4.46667h;97.2%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

6-[4-(6-hydroxy-hexyloxy)-phenoxy]-hexan-1-ol
154876-99-0

6-[4-(6-hydroxy-hexyloxy)-phenoxy]-hexan-1-ol

Polymer, Mw 59900; Monomer(s): 1,4-bis(6-hydroxyhexyloxy)benzene; 1,1-methylenebis[4-isocyanatobenzene]

Polymer, Mw 59900; Monomer(s): 1,4-bis(6-hydroxyhexyloxy)benzene; 1,1-methylenebis[4-isocyanatobenzene]

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃; for 20h; Polymerization;97%
N-methyl-1,1,2,2,3,3,4,4-nonafluoro-N-(2-hydroxyethyl)butane-1-sulphonamide
34454-97-2

N-methyl-1,1,2,2,3,3,4,4-nonafluoro-N-(2-hydroxyethyl)butane-1-sulphonamide

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C22H18F9N3O5S
856220-61-6

C22H18F9N3O5S

Conditions
ConditionsYield
dibutyltin(II) dilaurate In n-heptane at 45℃; for 2.53333h; Product distribution / selectivity;97%
dibutyltin(II) dilaurate In n-heptane; toluene at 45℃; for 2.25 - 2.5h;
dibutyltin(II) dilaurate In toluene at 20 - 45℃; for 2.5h;
dibutyltin(II) dilaurate In HFE-7100 (C4F90CH3) at 45℃; for 2.5h;
dibutyltin(II) dilaurate In Petroleum ether at 45℃; for 2.5h;
n-Octylamine
111-86-4

n-Octylamine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

4,4'-bis(octylureido)diphenylmethane

4,4'-bis(octylureido)diphenylmethane

Conditions
ConditionsYield
Stage #1: n-Octylamine; di(4-isocyanatophenyl)methane In 1,4-dioxane at 40℃; for 2.5h;
Stage #2: With sulfuric acid In 1,4-dioxane at 40℃; for 3.5h;
96.4%
1,1-Dimethyl-2-trimethylsilanyloxy-ethylamine
38421-19-1

1,1-Dimethyl-2-trimethylsilanyloxy-ethylamine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

(2-Isocyanato-2-methyl-propoxy)-trimethyl-silane
123717-12-4

(2-Isocyanato-2-methyl-propoxy)-trimethyl-silane

Conditions
ConditionsYield
at 200℃;96%
1,1-dimethylhydrazine
57-14-7

1,1-dimethylhydrazine

toluene
108-88-3

toluene

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

4,4'-bis(diimethylamino-urea)diphenylmethane toluene complex

4,4'-bis(diimethylamino-urea)diphenylmethane toluene complex

Conditions
ConditionsYield
at 20℃; for 0.5h;96%
N-Methyldiethanolamine
105-59-9

N-Methyldiethanolamine

4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride
1107-00-2

4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

polymer, product of diol-diisocyanate condensation followed by polycondensation with dianhydride and heating; monomer(s): 4,4\-methylenebis(phenyl isocyanate); N-methyldiethanolamine; 4,4\-(hexafluoroisopropylidene)bis(phthalic anhydride)

polymer, product of diol-diisocyanate condensation followed by polycondensation with dianhydride and heating; monomer(s): 4,4\-methylenebis(phenyl isocyanate); N-methyldiethanolamine; 4,4\-(hexafluoroisopropylidene)bis(phthalic anhydride)

Conditions
ConditionsYield
Stage #1: N-Methyldiethanolamine; di(4-isocyanatophenyl)methane In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: 4,4'-(1,1,1,3,3,3-hexafluoroisopropylidene)diphthalic anhydride In N,N-dimethyl-formamide at 60 - 80℃;
Stage #3: for 15h; Heating; vacuum;
96%
propargyl alcohol
107-19-7

propargyl alcohol

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C21H18N2O4
20723-73-3

C21H18N2O4

Conditions
ConditionsYield
Stage #1: propargyl alcohol With dibutyltin dilaurate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: di(4-isocyanatophenyl)methane In N,N-dimethyl-formamide for 6h;
95%
With triethylamine In tetrahydrofuran at 20℃; for 24h; Solvent;73%
In benzene
With propylene glycol methyl ether acetate at 50 - 60℃; for 5.83333h;
2-hydroxyethylhydrazine
109-84-2

2-hydroxyethylhydrazine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

p,p'-diphenylmethanedi[2-(β-hydroxyethyl)-4-semicarbazide]
49805-23-4

p,p'-diphenylmethanedi[2-(β-hydroxyethyl)-4-semicarbazide]

Conditions
ConditionsYield
In isopropyl alcohol at 10℃; Addition;95%
N,N-diallyl-hydrazine
5164-11-4

N,N-diallyl-hydrazine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

C27H34N6O2
85095-62-1

C27H34N6O2

Conditions
ConditionsYield
In benzene 0-5 deg C, then 1 h at 20-25 deg C;95%
4-(trimethylsilyloxy)aniline
36309-42-9

4-(trimethylsilyloxy)aniline

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

4-<(trimethylsilyl)oxy>phenyl isocyanate
42003-65-6

4-<(trimethylsilyl)oxy>phenyl isocyanate

Conditions
ConditionsYield
at 200℃;95%
di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

12-[12-(12-hydroxy-dodecyloxy)-dodecyloxy]-dodecan-1-ol

12-[12-(12-hydroxy-dodecyloxy)-dodecyloxy]-dodecan-1-ol

Polymer, Mw 84400; Monomer(s): 13,26-dioxaoctatriacontane-1,38-diol; 1,1-methylenebis[4-isocyanatobenzene]

Polymer, Mw 84400; Monomer(s): 13,26-dioxaoctatriacontane-1,38-diol; 1,1-methylenebis[4-isocyanatobenzene]

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃; for 20h; Polymerization;95%
(S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine
22751-68-4, 60508-97-6, 60509-62-8, 70749-06-3, 118628-68-5

(S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Polymer; Monomers: (1S,2S)-N,N\-dimethyl-1,2-diphenylethane-1,2-diamine; bis(4-isocyanatophenyl)methane

Polymer; Monomers: (1S,2S)-N,N\-dimethyl-1,2-diphenylethane-1,2-diamine; bis(4-isocyanatophenyl)methane

Conditions
ConditionsYield
In dichloromethane at 20℃;95%
Cu(N4{14}(2-))
39060-36-1, 31075-94-2

Cu(N4{14}(2-))

di(4-isocyanatophenyl)methane
101-68-8

di(4-isocyanatophenyl)methane

Cu*(C10N4H2(CH3)4H8C(O)NH(C6H4)CH2(C6H4)NHC(O))

Cu*(C10N4H2(CH3)4H8C(O)NH(C6H4)CH2(C6H4)NHC(O))

Conditions
ConditionsYield
In chloroform Kinetics; to soln. of Cu complex was added 4,4'-diphenylmethane diisocyanate, themixt. was stirred at 25°C for 48 h under N2; ppt. was filtered off, washed with benzene, chloroform, n-hexane, driedin vac., elem. anal.;95%
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