DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:50-44-2
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiry6-Mercaptopurine CAS:50-44-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Cas:50-44-2
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inquiryProduct Detail Minimum Order Qty. 10 Gram
Cas:50-44-2
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
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inquirymoderate price & quick delivery. Appearance:yellowish-greenish solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:antineoplastic, immo
Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
6-mercaptopurine properties Melting point 241-244 ° C Store at RT Acidity (pKa) 7.77, 11.17 (at 25 ° C) CAS Database 50-44-2 (CAS DataBase Reference) EPA chemical information 6H-Purine-6-thione, 1,7-dihydro- (50-44-2) 6-mercapto
Cas:50-44-2
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inquiryHuarong Industrial Group Limited established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World.
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Appearance:Substance Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Metabolism Drug; Carcino-Chemotherapeutic Drug Transportation:by sea Port:Shanghai,Qingdao Port
Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
6-Mercaptopurine Basic information Product Name: 6-Mercaptopurine Synonyms: THIOPURINE;mercaptopurine,6-MP;mercaptopurin;mercapurin;merkaptopuryna;mern;nci-c04886;nsc755 CAS: 50-44-2 MF: C5H4N4S MW: 152.18 EINECS: 200-037-4 Product
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:50-44-2
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inquiryProduct name: Mercaptopurine CAS No,: 50-44-2 Molecule Formula:C5H6N4 Molecule Weight:122.13 Purity: 98.5% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING I
Cas:50-44-2
Min.Order:1 Kilogram
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inquiryConditions | Yield |
---|---|
With potassium hydrosulfide und Erwaermen des Reaktionsprodukts mit einem Gemisch von Jod, konz.HI und rotem Phosphor; |
[1,3]thiazolo[5,4-d]pyrimidin-7-amine
formamide
6H-purine-6-thione
Conditions | Yield |
---|---|
at 190℃; | |
at 190℃; |
6-amino-5-formylamino-3H-pyrimidin-4-one
6H-purine-6-thione
Conditions | Yield |
---|---|
With pyridine; tetraphosphorus decasulfide | |
With tetraphosphorus decasulfide; tetralin |
N-(4-amino-6-thioxo-1,6-dihydro-pyrimidin-5-yl)-formamide
6H-purine-6-thione
Conditions | Yield |
---|---|
With formamide at 200℃; |
5-Aminoimidazole-4-thioamide
formamide
6H-purine-6-thione
Conditions | Yield |
---|---|
at 200℃; |
Conditions | Yield |
---|---|
With ethanol |
Conditions | Yield |
---|---|
With tetraphosphorus decasulfide; tetralin | |
With pyridine; tetraphosphorus decasulfide | |
Multi-step reaction with 2 steps 1: N,N-dimethyl-aniline; POCl3 2: ethanol View Scheme |
S6-(N-methyl-N-methoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; Mechanism; pH 7.1; |
S6-(N-methyl-N-ethoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; pH 7.1; |
S6-(N-ethyl-N-methoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; pH 7.1; |
S6-(N-ethyl-N-ethoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; pH 7.1; |
S6-(N-butyl-N-methoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; pH 7.1; |
S6-(N-methyl-N-butoxycarbonyl)aminomethyl-6-mercaptopurine
6H-purine-6-thione
Conditions | Yield |
---|---|
With phosphate buffer; water at 32℃; Rate constant; pH 7.1; |
acetic anhydride
7-(dimethylamino)methyl-6-mercaptopurine
A
6H-purine-6-thione
B
7-acetyloxymethyl-6-mercaptopurine
C
9-acetyloxymethyl-6-mercaptopurine
D
S6,3-bisacetyloxymethyl-6-mercaptopurine
Conditions | Yield |
---|---|
With sodium acetate In dimethylsulfoxide-d6 for 20h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
6-thiocyanato-7(9)H-purine
tetrachloromethane
water
6H-purine-6-thione
Conditions | Yield |
---|---|
at 25℃; Kinetics; |
6H-purine-6-thione
Conditions | Yield |
---|---|
at 240℃; |
8-chloroxanthine
6H-purine-6-thione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: N,N-dimethyl-aniline; POCl3 2: aqueous KHS / und Erwaermen des Reaktionsprodukts mit einem Gemisch von Jod, konz.HI und rotem Phosphor View Scheme |
N-(4-amino-6-benzylsulfanyl-pyrimidin-5-yl)-formamide
6H-purine-6-thione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium; liquid NH3 2: formamide / 200 °C View Scheme |
Conditions | Yield |
---|---|
With triethylamine In ethanol for 24h; Reflux; Inert atmosphere; Schlenk technique; Darkness; | 89% |
Conditions | Yield |
---|---|
With potassium hydroxide In water; N,N-dimethyl-formamide for 2h; | 87% |
6H-purine-6-thione
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione; C24H24Cl2N4Ru With triethylamine In ethanol for 24h; Reflux; Inert atmosphere; Schlenk technique; Darkness; Stage #2: ammonium hexafluorophosphate In ethanol; water Inert atmosphere; Schlenk technique; Darkness; | 83% |
6H-purine-6-thione
N-(4-Nitrobenzoyl)-1-pyrrolidinecarbimidoyl Chloride
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide at 80℃; for 1.5h; | 72% |
D-glucose pentaacetate
6H-purine-6-thione
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With ammonium sulfate; chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; saccharin In acetonitrile for 5h; Vorbrueggen Nucleoside Synthesis; Reflux; Inert atmosphere; Stage #2: D-glucose pentaacetate With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Reflux; | 68% |
6H-purine-6-thione
D-galactose pentaacetate
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With ammonium sulfate; chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; saccharin In acetonitrile for 5h; Vorbrueggen Nucleoside Synthesis; Reflux; Inert atmosphere; Stage #2: D-galactose pentaacetate With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Reflux; | 63% |
6H-purine-6-thione
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide 1.) 80 deg C, 5 h, 2.) RT, 2 d; | 62% |
6H-purine-6-thione
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide 1.) 80 deg C, 5 h, 2.) RT, 2 d; | 60% |
6H-purine-6-thione
Conditions | Yield |
---|---|
With NaOH In methanol; water org. ligand suspended in aq. MeOH; pH adjusted to 8-9 (aq. NaOH); Ru complex added; mixt. refluxed for 3 h at 90°C; cooled to room temp.;NaClO4 added; mixt. concd. by rotary evaporator; recrystd. (H2O/MeOH); elem. anal.; | 60% |
6H-purine-6-thione
1,2,3,4-tetra-O-acetyl-D-xylopyranose
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With ammonium sulfate; chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; saccharin In acetonitrile for 5h; Vorbrueggen Nucleoside Synthesis; Reflux; Inert atmosphere; Stage #2: 1,2,3,4-tetra-O-acetyl-D-xylopyranose With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Reflux; | 60% |
1,2,3,4-Tetra-O-acetyl-D-lyxopyranose
6H-purine-6-thione
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With ammonium sulfate; chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; saccharin In acetonitrile for 5h; Vorbrueggen Nucleoside Synthesis; Reflux; Inert atmosphere; Stage #2: 1,2,3,4-Tetra-O-acetyl-D-lyxopyranose With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Reflux; | 58% |
D-Mannose pentaacetate
6H-purine-6-thione
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With ammonium sulfate; chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; saccharin In acetonitrile for 5h; Vorbrueggen Nucleoside Synthesis; Reflux; Inert atmosphere; Stage #2: D-Mannose pentaacetate With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Reflux; | 55% |
Conditions | Yield |
---|---|
With potassium hydroxide In ethanol; water for 2h; | 53% |
6H-purine-6-thione
Chloromethyl pivalate
A
S6,9-bispivaloyloxymethyl-6-mercaptopurine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane Ambient temperature; | A 45% B 8% C 0.3% D 1% |
6H-purine-6-thione
bis(6-purinyl) disulfide
Conditions | Yield |
---|---|
With iodine; potassium iodide In phosphate buffer at 40℃; pH=7.5; | 41% |
6H-purine-6-thione
6-Bromo-2-(1-bromoethyl)-3-phenyl-4H-chromen-4-one
2-(1-(9H-Purin-6-ylthio)ethyl)-6-bromo-3-phenyl-4H-chromen-4-one
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: 6-Bromo-2-(1-bromoethyl)-3-phenyl-4H-chromen-4-one In N,N-dimethyl-formamide for 12h; | 37% |
6H-purine-6-thione
fac-[CoCl3(1,4,7-triazacyclononane)]
Conditions | Yield |
---|---|
With NaOH; Sephadex A-25, ClO4-form In water pH-adjustment of soln. of equimolar amts. Co-complex and purine to 8-9 (NaOH, repeated evapn. to dryness at 60°C (stirring) and dissoln. in water; concn., filtration off of trimer, chromy. (Sephadex C25, ClO4-form, hot water), crystn. (two crops); elem. anal.; | A 20% B 36% |
6H-purine-6-thione
N-[1-Chloro-1-piperidin-1-yl-meth-(Z)-ylidene]-4-nitro-benzamide
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 72h; Ambient temperature; | A 32% B 35% |
6H-purine-6-thione
2-(Bromomethyl)-3-phenyl-4H-chromen-4-one
2-((9H-Purin-6-ylthio)methyl)-3-phenyl-4H-chromen-4-one
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: 2-(Bromomethyl)-3-phenyl-4H-chromen-4-one In N,N-dimethyl-formamide for 12h; | 33% |
6H-purine-6-thione
6-Bromo-2-(bromomethyl)-3-phenyl-4H-chromen-4-one
2-[(9H-Purin-6-ylthio)methyl]-6-bromo-3-phenyl-4H-chromen-4-one
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: 6-Bromo-2-(bromomethyl)-3-phenyl-4H-chromen-4-one In N,N-dimethyl-formamide for 12h; | 28% |
6H-purine-6-thione
Conditions | Yield |
---|---|
Stage #1: 6H-purine-6-thione; C29H23ClN5Ru In methanol; water Reflux; Inert atmosphere; Schlenk technique; Darkness; Stage #2: ammonium hexafluorophosphate In ethanol; water Inert atmosphere; Schlenk technique; Darkness; | 27% |
Conditions | Yield |
---|---|
With triethylamine In ethanol for 24h; Reflux; Inert atmosphere; Schlenk technique; Darkness; | 27% |
6H-purine-6-thione
Conditions | Yield |
---|---|
With triethylamine In methanol; water Reflux; Darkness; Schlenk technique; Inert atmosphere; | 16% |
Conditions | Yield |
---|---|
With hydrogen bromide In water at 70℃; for 3h; pH=Ca. 1 - 2; | 3.8% |
Conditions | Yield |
---|---|
In dimethyl sulfoxide Ambient temperature; | 2.5% |
Conditions | Yield |
---|---|
With sodium hydroxide; diethyl ether |
2-Chloromethylthiophene
6H-purine-6-thione
6-[2]thienylmethylsulfanyl-7(9)H-purine
Conditions | Yield |
---|---|
With potassium carbonate; N,N-dimethyl-formamide |
Conditions | Yield |
---|---|
With ethanol |
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