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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Aldosterone

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Aldosterone 52-39-1 Producer

Cas:52-39-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Aldosterone

Cas:52-39-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

52-39-1 ALDOSTERONE

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

ALDOSTERONE 52-39-1

Cas:52-39-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 52-39-1 with competitive price

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)- 52-39-1

Cas:52-39-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

ALDOSTERONE CAS: 52-39-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

ALDOSTERONE CAS: 52-39-1

Cas:52-39-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)-

Cas:52-39-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)-

Cas:52-39-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Aldosterone 52-39-1

Cas:52-39-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

ALDOSTERONE

Cas:52-39-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)-

Cas:52-39-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

ALDOSTERONE CAS 52-39-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,

ALDOSTERONE CAS 52-39-1

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Aldosterone manufacturer

Cas:52-39-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

ALDOSTERONE

Cas:52-39-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

Aldosterone.99%

Cas:52-39-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Aldosterone 52-39-1

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed produc

High Quality ALDOSTERONE 52-39-1 Manufacturer

Cas:52-39-1

Min.Order:1 Kilogram

FOB Price: $34.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Aldosterone 52-39-1

Cas:52-39-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

Aldosterone

Cas:52-39-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Aldosterone 52-39-1

Cas:52-39-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Aldosterone 52-39-1

Cas:52-39-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)-

Cas:52-39-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Greenutra Resource Inc

AldosteroneAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

Aldosterone

Cas:52-39-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Aldosterone

Cas:52-39-1

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

aldosterone

Cas:52-39-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Pregn-4-en-18-al,11,21-dihydroxy-3,20-dioxo-, (11b)-

Cas:52-39-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Aldosterone 5mg

Cas:52-39-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

ALDOSTERONE(SH)

Cas:52-39-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

3,3;20,20-bis-ethanediyldioxy-11β,21-dihydroxy-pregn-5-en-18-al
124537-57-1

3,3;20,20-bis-ethanediyldioxy-11β,21-dihydroxy-pregn-5-en-18-al

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
With hydrogenchloride
Pregnenolone
145-13-1

Pregnenolone

A

Corticosterone
50-22-6

Corticosterone

B

aldosterone
52-39-1

aldosterone

C

18,21-dihydroxy-4-pregnen-3,20-dione
10385-97-4

18,21-dihydroxy-4-pregnen-3,20-dione

Conditions
ConditionsYield
With air; dibutyric cyclic AMP; NaHCO3 buffer; normal male Sprague-Dawley rat adrenal glands after feeding for 72 h with 1 percent NaCl at 37℃; for 3h; Product distribution; tritium labeled study;
aldosterone 21-acetate
297-91-6

aldosterone 21-acetate

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: chromium (VI)-oxide; acetic acid
2: methanol; concentrated aqueous hydrochloric acid
3: ethylene glycol; toluene-4-sulfonic acid / 0.2 Torr
4: dioxane; lithium alanate; diethyl ether
5: aqueous HCl
View Scheme
11β,21-dihydroxy-3,20-dioxo-pregn-4-en-18-oic acid-11-lactone
2507-89-3

11β,21-dihydroxy-3,20-dioxo-pregn-4-en-18-oic acid-11-lactone

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethylene glycol; toluene-4-sulfonic acid / 0.2 Torr
2: dioxane; lithium alanate; diethyl ether
3: aqueous HCl
View Scheme
21-acetoxy-11β-hydroxy-3,20-dioxo-pregn-4-en-18-oic acid-lactone
3329-80-4

21-acetoxy-11β-hydroxy-3,20-dioxo-pregn-4-en-18-oic acid-lactone

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: methanol; concentrated aqueous hydrochloric acid
2: ethylene glycol; toluene-4-sulfonic acid / 0.2 Torr
3: dioxane; lithium alanate; diethyl ether
4: aqueous HCl
View Scheme
3,3;20,20-bis-ethanediyldioxy-11β,21-dihydroxy-pregn-5-en-18-oic acid-11-lactone
86698-82-0

3,3;20,20-bis-ethanediyldioxy-11β,21-dihydroxy-pregn-5-en-18-oic acid-11-lactone

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dioxane; lithium alanate; diethyl ether
2: aqueous HCl
View Scheme
C21H30O2*C42H70O35
117824-25-6

C21H30O2*C42H70O35

A

11-alpha-hydroxyprogesterone
80-75-1

11-alpha-hydroxyprogesterone

B

20-hydroxy-pregnan-18-oic acid

20-hydroxy-pregnan-18-oic acid

C

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
With potassium dihydrogenphosphate; magnesium sulfate heptahydrate; L-asparagine; D-glucose In ethanol; water at 30℃; for 72h; pH=5.5; Time; Concentration; Microbiological reaction; Overall yield = 62.95 %Chromat.;A 48.25 %Chromat.
B 6.84 %Chromat.
C 7.86 %Chromat.
Progesterone
57-83-0

Progesterone

A

11-alpha-hydroxyprogesterone
80-75-1

11-alpha-hydroxyprogesterone

B

20-hydroxy-pregnan-18-oic acid

20-hydroxy-pregnan-18-oic acid

C

aldosterone
52-39-1

aldosterone

Conditions
ConditionsYield
With potassium dihydrogenphosphate; magnesium sulfate heptahydrate; L-asparagine; D-glucose; β‐cyclodextrin In ethanol; water at 30℃; for 48h; pH=5.5; Solvent; Reagent/catalyst; Time; Concentration; Microbiological reaction; Overall yield = 87.15 %Chromat.;A 71.33 %Chromat.
B 8.58 %Chromat.
C 7.24 %Chromat.
aldosterone
52-39-1

aldosterone

4-bromoaldosterone

4-bromoaldosterone

Conditions
ConditionsYield
With oxone; triethylamine; sodium bromide In tetrahydrofuran; water at 20℃; for 3h;83%
aldosterone
52-39-1

aldosterone

C21H27ClO4

C21H27ClO4

Conditions
ConditionsYield
Stage #1: aldosterone With dmap; methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 20℃; for 1h;
Stage #2: With lithium chloride In N,N-dimethyl-formamide at 60℃; for 2h;
80.9%
Stage #1: aldosterone With dmap; methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 20℃; for 1h;
Stage #2: With lithium chloride In N,N-dimethyl-formamide at 60℃; for 2h;
80.9%
aldosterone
52-39-1

aldosterone

diethyl malonate
105-53-3

diethyl malonate

C28H40O9

C28H40O9

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran at 0 - 20℃; for 6h; Schlenk technique;57%
aldosterone
52-39-1

aldosterone

(18Ξ)-11β,18-epoxy-18-hydroxy-3-oxo-androst-4-ene-17β-carboxylic acid-lactone
21966-75-6

(18Ξ)-11β,18-epoxy-18-hydroxy-3-oxo-androst-4-ene-17β-carboxylic acid-lactone

Conditions
ConditionsYield
With methanol; sodium periodate
aldosterone
52-39-1

aldosterone

acetic anhydride
108-24-7

acetic anhydride

Aldosterone 18,21-diacetate
3329-79-1

Aldosterone 18,21-diacetate

Conditions
ConditionsYield
With pyridine
aldosterone
52-39-1

aldosterone

A

2C21H27O8S(1-)*2H4N(1+)*3H2O

2C21H27O8S(1-)*2H4N(1+)*3H2O

B

aldosterone 21-ammonium sulphate

aldosterone 21-ammonium sulphate

C

2C21H27O8S(1-)*2H4N(1+)*3H2O

2C21H27O8S(1-)*2H4N(1+)*3H2O

D

2C21H27O8S(1-)*2H4N(1+)*3H2O

2C21H27O8S(1-)*2H4N(1+)*3H2O

Conditions
ConditionsYield
With triethylamine sulfur trioxide In pyridine at 20℃; for 4h; Yield given. Title compound not separated from byproducts;
aldosterone
52-39-1

aldosterone

A

20β-dihydroaldosterone 18,11β-hemiacetal

20β-dihydroaldosterone 18,11β-hemiacetal

B

C21H28(2)H2O5

C21H28(2)H2O5

Conditions
ConditionsYield
With Tris-HCl buffer; 1,4-dihydronicotinamide adenine dinucleotide for 7h; Ambient temperature; 3α,20β-hydroxysteroid dehydrogenase;
aldosterone
52-39-1

aldosterone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

aldosterone 21-TBDMS ether
113249-21-1

aldosterone 21-TBDMS ether

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane for 0.166667h;30 mg
aldosterone
52-39-1

aldosterone

A

11β,21-dihydroxy-3,20-dioxo-5α-pregnan-18-al
6251-71-4

11β,21-dihydroxy-3,20-dioxo-5α-pregnan-18-al

B

11β,21-dihydroxy-3,20-dioxo-5β-pregnan-18-al
7305-52-4

11β,21-dihydroxy-3,20-dioxo-5β-pregnan-18-al

C

3α,11β,21-trihydroxy-20-oxo-5β-pregnan-18-al
2527-07-3

3α,11β,21-trihydroxy-20-oxo-5β-pregnan-18-al

D

3α,11β,21-trihydroxy-20-oxo-5α-pregnan-18-al

3α,11β,21-trihydroxy-20-oxo-5α-pregnan-18-al

E

3β,11β,21-trihydroxy-20-oxo-5α-pregnan-18-al

3β,11β,21-trihydroxy-20-oxo-5α-pregnan-18-al

F

3β,11β,21-trihydroxy-20-oxo-5β-pregnan-18-al

3β,11β,21-trihydroxy-20-oxo-5β-pregnan-18-al

G

polar metabolites

polar metabolites

Conditions
ConditionsYield
With Tris-HCl buffer; adult male Sprague-Dawley rat liver microsomes; NADPH; magnesium chloride at 37℃; for 0.0833333h; Kinetics; <3H>labeled, Km, Vmax;
aldosterone
52-39-1

aldosterone

C22H31(2)H2NO5

C22H31(2)H2NO5

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tris-HCl buffer, NADH / 7 h / Ambient temperature; 3α,20β-hydroxysteroid dehydrogenase
2: pyridine / Ambient temperature
View Scheme
aldosterone
52-39-1

aldosterone

C23H34(2)H2N2O5

C23H34(2)H2N2O5

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tris-HCl buffer, NADH / 7 h / Ambient temperature; 3α,20β-hydroxysteroid dehydrogenase
2: pyridine / Ambient temperature
View Scheme
aldosterone
52-39-1

aldosterone

3β,11β-dihydroxy-18-nor-5α-androstane-13β,17β-dicarboxylic acid-13=>11-lactone
112442-39-4

3β,11β-dihydroxy-18-nor-5α-androstane-13β,17β-dicarboxylic acid-13=>11-lactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol; aqueous sodium periodate solution
2: platinum; acetic acid / Erhitzen des Reaktionsprodukts mit Hydrazin-hydrat und Natriumaethylat in Aethanol auf 150grad
View Scheme
aldosterone
52-39-1

aldosterone

3β,11β-dihydroxy-18-nor-5α-androstane-13β,17β-dicarboxylic acid-13=>11-lactone-17-methyl ester
102443-94-7

3β,11β-dihydroxy-18-nor-5α-androstane-13β,17β-dicarboxylic acid-13=>11-lactone-17-methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: methanol; aqueous sodium periodate solution
2: platinum; acetic acid; pyridine / Hydrogenation.Reaktion ueber zwei Stufen
3: hydrazine hydrate; sodium ethylate; ethanol / 150 °C / Behandeln des Reaktionsprodukts mit Diazomethan in Aether
View Scheme
aldosterone
52-39-1

aldosterone

(18Ξ)-3β-acetoxy-11β,18-epoxy-18-hydroxy-5α-androstane-17β-carboxylic acid-lactone
124222-50-0

(18Ξ)-3β-acetoxy-11β,18-epoxy-18-hydroxy-5α-androstane-17β-carboxylic acid-lactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol; aqueous sodium periodate solution
2: platinum; acetic acid; pyridine / Hydrogenation.Reaktion ueber zwei Stufen
View Scheme
aldosterone
52-39-1

aldosterone

C34H51NO8

C34H51NO8

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
View Scheme
aldosterone
52-39-1

aldosterone

C25H35NO6

C25H35NO6

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
4.1: hydrogenchloride / 1,4-dioxane / 5 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
4.1: hydrogenchloride / 1,4-dioxane / 5 h / 20 °C
View Scheme
aldosterone
52-39-1

aldosterone

C29H43NO6

C29H43NO6

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 40 °C
View Scheme
Multi-step reaction with 2 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
View Scheme
aldosterone
52-39-1

aldosterone

C26H37NO6

C26H37NO6

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
4.1: hydrogenchloride / 1,4-dioxane / 5 h / 20 °C
5.1: thionyl chloride / 0 - 70 °C
View Scheme
aldosterone
52-39-1

aldosterone

C25H37NO5

C25H37NO5

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
4.1: hydrogenchloride / 1,4-dioxane / 5 h / 20 °C
5.1: thionyl chloride / 0 - 70 °C
6.1: sodium tetrahydroborate / methanol / 0 - 20 °C
View Scheme
aldosterone
52-39-1

aldosterone

C29H38N2O6

C29H38N2O6

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: dmap; methanesulfonyl chloride; triethylamine / dichloromethane / 1 h / 0 - 20 °C
1.2: 2 h / 60 °C
2.1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 3 h / 20 - 40 °C
3.1: triethylamine / dichloromethane / 1 h / 10 - 20 °C
4.1: hydrogenchloride / 1,4-dioxane / 5 h / 20 °C
5.1: thionyl chloride / 0 - 70 °C
6.1: sodium tetrahydroborate / methanol / 0 - 20 °C
7.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 70 °C / Inert atmosphere
View Scheme

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