As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
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inquiry2-Amino-4,6-dichloropyrimidine Basic information Product Name: 2-Amino-4,6-dichloropyrimidine Synonyms: TIMTEC-BB SBB003919;LABOTEST-BB LT00080771;AKOS 90013;ADCP;4
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryProduct Name 2-Amino-4,6-dichloropyrimidine CAS NO. 56-05-3 Formula C4H3CL2N3 Molecular Weight 163.9927 Appearance
1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
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inquiryAbout Product Details Items Specifications Test Results Appearance White to white crystalline powde
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
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inquiryMassive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
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inquirysuperior quality Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:2 - amino - 4, 6 - dichloro pyrimidine is th
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
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inquiry2-Amino-4,6-dichloropyrimidine Chemical Properties Melting point 219-222 °C (lit.) Boiling point 219-222°C density 1.6662 (rough estimate) refractive index 1.6300 (estimate) pka 0.14±0.10(Predicted) form Liquid c
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inquiryCHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis
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inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
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inquiryfactory Storage:Shading, sealed and preserved. Package:Grams, Kilograms Application:An organic synthetic intermediate used Transportation:According to customer request Port:Qingdao
Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is
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inquiryhigh purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier
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inquiryJinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands
Cas:56-05-3
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inquiryConditions | Yield |
---|---|
With triethylamine; trichlorophosphate at 40 - 90℃; for 2h; | 98.8% |
With bis(trichloromethyl) carbonate In toluene at 70 - 75℃; for 6h; Reagent/catalyst; Temperature; Solvent; | 92% |
With thionyl chloride for 4h; Reagent/catalyst; Temperature; Reflux; | 92.7% |
Conditions | Yield |
---|---|
With sodium amide for 16h; Substitution; Heating; | 29% |
2,4,6-trichloropyrimidine
A
4-amino-2,6-dichloropyrimidine
B
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
With ethanol; ammonia | |
With ethanol; ammonia at 100℃; | |
With ethanol; ammonia at 20℃; | |
With sodium amide In dimethyl sulfoxide at 20℃; for 120h; Substitution; | A 244 mg B 55 mg |
2-aminopyrimidine-4,6-diol
A
2-Amino-4,6-dichloropyrimidine
B
2-amino-4,5,6-trichloropyrimidine
Conditions | Yield |
---|---|
With phosphorus pentachloride; trichlorophosphate |
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
With trichlorophosphate |
2,4,6-trichloropyrimidine
ammonia
A
4-amino-2,6-dichloropyrimidine
B
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
at 100℃; |
Conditions | Yield |
---|---|
With triethylamine; trichlorophosphate |
Conditions | Yield |
---|---|
With tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate In acetonitrile at 110℃; for 0.333333h; |
2-Amino-4,6-dichloropyrimidine
di-tert-butyl dicarbonate
tert-butyl N-tert-butoxycarbonyl-N-(4,6-dichloropyrimidin-2-yl)carbamate
Conditions | Yield |
---|---|
With dmap In tetrahydrofuran at 20℃; | 100% |
With dmap In tetrahydrofuran at 20℃; for 16h; | 97% |
With dmap In dichloromethane at 20℃; for 30h; | 97% |
2-Amino-4,6-dichloropyrimidine
(4-methylcyclohex-1-en-1-yl)boronic acid
4-chloro-6-(4-methylcyclohex-1-en-1-yl)pyrimidin-2-amine
Conditions | Yield |
---|---|
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water at 80℃; for 18h; | 100% |
2-Amino-4,6-dichloropyrimidine
5-(4-amino-2-fluorophenoxy)-1H-indazole
N-[2-amino-6-chloro-4-pyrimidinyl]-N-[3-fluoro-4-(1H-indazol-5-yloxy)phenyl]amine
Conditions | Yield |
---|---|
Stage #1: 2-Amino-4,6-dichloropyrimidine; 5-(4-amino-2-fluorophenoxy)-1H-indazole With hydrogenchloride In water at 100℃; Stage #2: With sodium hydrogencarbonate In water pH=> 7; | 100% |
2-Amino-4,6-dichloropyrimidine
tert-butylamine
2-amino-4-chloro-6-(1,1-dimethylethylamino)pyrimidine
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 150℃; for 1h; Microwave irradiation; | 100% |
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | 27% |
With triethylamine In acetonitrile at 170℃; for 2.25h; microwave irradiation; |
2-Amino-4,6-dichloropyrimidine
N-(4,6-dichloro-pyrimidin-2-yl)-2,2,2-trifluoro-acetamide
Conditions | Yield |
---|---|
With pyridine; trifluoroacetic anhydride In dichloromethane | 100% |
2-Amino-4,6-dichloropyrimidine
Cyclopentamine
6-chloro-4-N-cyclopentylpyrimidine-2,4-diamine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | 100% |
In methanol at 50℃; for 16h; Sealed tube; Inert atmosphere; | 93% |
In methanol at 60℃; for 7.5h; | |
In ethanol at 50 - 100℃; | |
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 100 - 160℃; Microwave irradiation; |
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 18h; Reagent/catalyst; Temperature; | 100% |
2-Amino-4,6-dichloropyrimidine
1-amino-2-propene
6-chloro-4-N-(prop-2-en-1-yl)pyrimidine-2,4-diamine
Conditions | Yield |
---|---|
With triethylamine for 21h; Ambient temperature; | 99% |
With triethylamine In neat (no solvent) Heating; | 85% |
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | 84% |
2-Amino-4,6-dichloropyrimidine
2-amino-4-hydroxy-6-iodopyrimidine
Conditions | Yield |
---|---|
With hydrogen iodide; sodium iodide In acetone at 100℃; for 0.0833333h; microwave irradiation; | 99% |
With hydrogen iodide; sodium iodide In acetone at 20℃; for 48h; | 86% |
2-Amino-4,6-dichloropyrimidine
isopropylamine
6-chloro-N4-isopropylpyrimidine-2,4-diamine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | 99% |
In methanol at 50℃; Sealed tube; Inert atmosphere; | 71% |
In sulfuric acid |
Conditions | Yield |
---|---|
With triethylamine In butan-1-ol at 110℃; for 12h; Inert atmosphere; | 99% |
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; |
2-Amino-4,6-dichloropyrimidine
cyclohexylamine
6-chloro-N4-cyclohexylpyrimidine-2,4-diamine
Conditions | Yield |
---|---|
In methanol at 50℃; for 48h; Inert atmosphere; Sealed tube; | 99% |
In methanol at 70℃; for 1h; | |
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | |
With triethylamine In ethanol at 80 - 90℃; for 0.666667h; Microwave irradiation; |
2-Amino-4,6-dichloropyrimidine
2-(N,N-dimethylamino)ethanol
4-chloro-6-(2-(dimethylamino)ethoxy)pyrimidin-2-amine
Conditions | Yield |
---|---|
With sodium hydride for 0.166667h; Microwave irradiation; | 99% |
2-Amino-4,6-dichloropyrimidine
2-(Diethylamino)ethanol
4-chloro-6-(2-(diethylamino)ethoxy)pyrimidin-2-amine
Conditions | Yield |
---|---|
With sodium hydride for 0.166667h; Microwave irradiation; | 99% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 95℃; | 99% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 85℃; | 99% |
Conditions | Yield |
---|---|
With triethylamine In ethanol; ethyl acetate | 98.7% |
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
With triethylamine In butan-1-ol for 46h; Heating; | 98% |
2-Amino-4,6-dichloropyrimidine
benzyl alcohol
2-amino-4-(benzyloxy)-6-chloropyrimidine
Conditions | Yield |
---|---|
Stage #1: benzyl alcohol With sodium hydride In tetrahydrofuran Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran; N,N-dimethyl-formamide | 98% |
Stage #1: benzyl alcohol With sodium hydride In dimethyl sulfoxide at 20℃; for 0.5h; Stage #2: 2-Amino-4,6-dichloropyrimidine In dimethyl sulfoxide at 80℃; for 5h; Inert atmosphere; | 75% |
Stage #1: benzyl alcohol With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.5h; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran; N,N-dimethyl-formamide at 100℃; for 1h; | |
Stage #1: benzyl alcohol With sodium hydride In tetrahydrofuran at 0 - 25℃; for 0.5h; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran; N,N-dimethyl-formamide at 100℃; for 1h; Sealed vial; |
Conditions | Yield |
---|---|
Stage #1: 2-Amino-4,6-dichloropyrimidine With thiourea In ethanol for 2h; Reflux; Stage #2: With water; sodium hydroxide at 80℃; for 16h; | 98% |
2-Amino-4,6-dichloropyrimidine
3-Dimethylamino-1-propanol
4-chloro-6-(3-(dimethylamino)propoxy)pyrimidin-2-amine
Conditions | Yield |
---|---|
With sodium hydride for 0.166667h; Microwave irradiation; | 98% |
methanol
2-Amino-4,6-dichloropyrimidine
sodium methylate
2-amino-4-chloro-6-methoxypyrimidine
Conditions | Yield |
---|---|
at 17℃; for 4.5h; Product distribution / selectivity; Heating / reflux; | 97% |
for 20h; Heating / reflux; | 90% |
Conditions | Yield |
---|---|
With sodium at 70℃; for 23.5h; | 97% |
Stage #1: ethanol With sodium hydride In tetrahydrofuran for 0.25h; Inert atmosphere; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran for 15h; Inert atmosphere; | 94% |
With sodium hydride for 12h; Reflux; Inert atmosphere; | 89% |
With sodium hydride In mineral oil at 20℃; for 12h; Reflux; Inert atmosphere; | 89% |
Conditions | Yield |
---|---|
With sodium hydroxide for 1h; Heating; | 96% |
With sodium hydroxide In water for 2h; Reflux; | 95% |
With sodium hydroxide In water for 5h; Reflux; | 86% |
2-Amino-4,6-dichloropyrimidine
4-Aminobenzonitrile
4-[(2-amino-6-chloropyrimidin-4-yl)amino]benzonitrile
Conditions | Yield |
---|---|
With hydrogenchloride In water at 100℃; | 96% |
2-Amino-4,6-dichloropyrimidine
2,2,2-trifluoroethanol
4,6-bis(2,2,2-trifluoroethoxy)pyrimidine-2-amine
Conditions | Yield |
---|---|
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran at 0℃; for 0.0166667h; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran at 62℃; for 15h; | 96% |
Stage #1: 2,2,2-trifluoroethanol With sodium hydride In tetrahydrofuran for 0.25h; Inert atmosphere; Stage #2: 2-Amino-4,6-dichloropyrimidine In tetrahydrofuran for 15h; Inert atmosphere; | 94% |
With sodium hydride In tetrahydrofuran at 0 - 62℃; for 15h; Inert atmosphere; | 94% |
2-Amino-4,6-dichloropyrimidine
N-benzylhydrazine hydrochloride
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 60℃; for 3h; | 96% |
2-Amino-4,6-dichloropyrimidine
sodium methylate
2-amino-4-chloro-6-methoxypyrimidine
Conditions | Yield |
---|---|
In acetone at 17 - 30℃; for 6.5h; Product distribution / selectivity; | 95.3% |
In acetic acid methyl ester at 17 - 30℃; for 6.5h; Product distribution / selectivity; | 94.6% |
In methanol for 20h; Heating / reflux; | 90% |
2-Amino-4,6-dichloropyrimidine
Conditions | Yield |
---|---|
With sodium carbonate In Isopropyl acetate; water at 78 - 80℃; for 12.5h; Reagent/catalyst; Temperature; Solvent; Time; Inert atmosphere; Sealed tube; Industrial scale; | 95.2% |
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