Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 59702-31-7 N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Ethyl-2,3-piperazinedione

Cas:59702-31-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Leader Biochemical Group

About Product Technical Details

China Largest factory Manufacturer Supply Highest Quality 1-Ethyl-2,3-dioxopiperazine CAS 59702-31-7

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product name N-Ethyl-2,3-dioxopiperazine CAS 59702-31-7 Assay 99% Appearance Yellow

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--59702-31-7--High purity N-Ethyl-2,3-dioxopiperazine factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established

TIANFUCHEM--59702-31-7--High purity N-Ethyl-2,3-dioxopiperazine factory price

Cas:59702-31-7

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 59702-31-7 with best quality

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

N-Ethyl-2,3-dioxopiperazine 59702-31-7

Cas:59702-31-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: 4-Ethyl-2,3-dioxo-piperazine Synonyms: N-Ethyl-2,3-dioxopiperazine CAS No.: 59702-31-7 Molecular Formula: C6H10N2O2 Properties: white to pale yellow crystalline powder Application: The important intermediate of Pipera

4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride cas no 59703-00-3

Cas:59702-31-7

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3-Piperazinedione,1-ethyl- 59702-31-7

Cas:59702-31-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1-Ethyl-2,3-dioxopiperazine CAS:59702-31-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

1-Ethyl-2,3-dioxopiperazine CAS:59702-31-7

Cas:59702-31-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,3-Piperazinedione,1-ethyl-

Cas:59702-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

N-Ethyl-2,3-Dioxopiperazine

Cas:59702-31-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Ethyl-2,3-dioxypiperazine

Cas:59702-31-7

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide interm

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 4-Ethyl-2,3-Dioxo-Piperazine CAS No.:59702-31-7 Molecule Formula:C6H10N2O2 Molecule Weight:142.16 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

High Quality 4-Ethyl-2,3-Dioxo-Piperazine

Cas:59702-31-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

1-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

1-Ethyl-2,3-dioxopiperazine Basic information Product Name: 1-Ethyl-2,3-dioxopiperazine Synonyms: Piperacillin EP Impurity E;Piperacillin EP Impurity E (1-Ethyl-2,3-dioxopiperazine);Piperacillin Sodium EP Impurity E;3-dioxopiperazine;Piperacil

1-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

N-Ethyl-2,3-dioxopiperazine

Cas:59702-31-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

NANJING SUNNY PHARMATECH CO., LTD

Our product has a very high quality and now we are exporting to customers overseas with very positive feedback. With best price, quality and service from Nanjing Sunny, we are confident to set up a very nice cooperation with customers all over the w

4-Ethyl-2,3-dioxo-piperazine

Cas:59702-31-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

2,3-Piperazinedione,1-ethyl-

Cas:59702-31-7

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

N-ethylethane-1,2-diamine
110-72-5

N-ethylethane-1,2-diamine

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

Conditions
ConditionsYield
With acetic acid In methanol at 15 - 50℃; for 1h; Reagent/catalyst;83.21%
6-<(+/-)-α-amino-α-(2-aminothiazol-4-yl)acetamido>penicillanic acid
85208-10-2

6-<(+/-)-α-amino-α-(2-aminothiazol-4-yl)acetamido>penicillanic acid

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
59703-00-3

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride

A

6-<(+/-)-α-(2-aminothiazol-4-yl)-α-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)acetamido>penicillanic acid
85208-19-1, 85208-20-4, 85280-44-0

6-<(+/-)-α-(2-aminothiazol-4-yl)-α-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)acetamido>penicillanic acid

B

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

Conditions
ConditionsYield
With sodium hydrogencarbonate 1.) THF, H2O, 0 deg C, 2.) pH=7-7.5, room temperature, 1 h;A 21%
B n/a
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

A

1-ethyl-4-(mercaptomethyl)-piperazine-2,3-dione

1-ethyl-4-(mercaptomethyl)-piperazine-2,3-dione

B

1-ethyl-4-(hydroxymethyl)-piperazine-2,3-dione

1-ethyl-4-(hydroxymethyl)-piperazine-2,3-dione

Conditions
ConditionsYield
With potassium hydroxide In formaldehydA 100%
B n/a
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
59703-00-3

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride

Conditions
ConditionsYield
With pyridine; dmap; chloro-trimethyl-silane In dichloromethane at -25 - -20℃;94.3%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 10 - 20℃; for 1.06667h; Temperature; Reagent/catalyst; Green chemistry;93.9%
Stage #1: 1-ethyl-2,3-dioxo-piperazine With chloro-trimethyl-silane; triethylamine In dichloromethane at 0 - 20℃; for 1h; Inert atmosphere; Schlenk technique;
Stage #2: bis(trichloromethyl) carbonate In dichloromethane at -30℃; Inert atmosphere; Schlenk technique;
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

C13H17NO4

C13H17NO4

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C20H25N3O7

C20H25N3O7

Conditions
ConditionsYield
Stage #1: 1-ethyl-2,3-dioxo-piperazine With chloro-trimethyl-silane; triethylamine In dichloromethane at 20℃; for 1h; Cooling with ice;
Stage #2: bis(trichloromethyl) carbonate In dichloromethane at -30℃; for 1h;
Stage #3: C13H17NO4 With chloro-trimethyl-silane; triethylamine In dichloromethane at -40℃; for 1.5h; Cooling with ice;
86%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

C10H15N3O4S

C10H15N3O4S

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C17H23N5O7S

C17H23N5O7S

Conditions
ConditionsYield
Stage #1: 1-ethyl-2,3-dioxo-piperazine With chloro-trimethyl-silane; triethylamine In dichloromethane at 20℃; for 1h; Cooling with ice;
Stage #2: bis(trichloromethyl) carbonate In dichloromethane at -30℃; for 1h;
Stage #3: C10H15N3O4S With chloro-trimethyl-silane; triethylamine In dichloromethane at -40 - 20℃; for 2.5h; Cooling with ice;
86%
5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

1-ethyl-4-{4-[5-hydroxy-2-(4-hydroxyphenyl)-3-methyl-1H-indol-1-yl]butyl}piperazinedione

1-ethyl-4-{4-[5-hydroxy-2-(4-hydroxyphenyl)-3-methyl-1H-indol-1-yl]butyl}piperazinedione

Conditions
ConditionsYield
Stage #1: 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole; 1-ethyl-2,3-dioxo-piperazine With triethylamine In butan-1-ol for 4h; Reflux;
Stage #2: With palladium 10% on activated carbon In ethyl acetate; ethanethiol; butan-1-ol at 45℃; for 24h;
49.1%
5,5'-diallyl-3-(chloromethyl)[1,1'-biphenyl]-2,2'-diol

5,5'-diallyl-3-(chloromethyl)[1,1'-biphenyl]-2,2'-diol

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

1-((5,5'-diallyl-2,2'-dihydroxy-[1,1'-biphenyl]-3-yl)methyl)-4-ethylpiperazine-2,3-dione

1-((5,5'-diallyl-2,2'-dihydroxy-[1,1'-biphenyl]-3-yl)methyl)-4-ethylpiperazine-2,3-dione

Conditions
ConditionsYield
With caesium carbonate; potassium iodide In acetonitrile at 80℃;31.1%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

1-Ethyl-4-trimethylsilanyl-piperazine-2,3-dione

1-Ethyl-4-trimethylsilanyl-piperazine-2,3-dione

Conditions
ConditionsYield
With triethylamine In chloroform for 1h; Heating;
With triethylamine In dichloromethane at -10 - 0℃; for 0.2h; Solvent; Reagent/catalyst;
ethyl (4-benzothiazol-2-ylbenzyl)phosphonochloridate hydrochloride
104608-47-1

ethyl (4-benzothiazol-2-ylbenzyl)phosphonochloridate hydrochloride

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

(4-Benzothiazol-2-yl-benzyl)-(4-ethyl-2,3-dioxo-piperazin-1-yl)-phosphinic acid ethyl ester
127881-48-5

(4-Benzothiazol-2-yl-benzyl)-(4-ethyl-2,3-dioxo-piperazin-1-yl)-phosphinic acid ethyl ester

Conditions
ConditionsYield
Yield given. Multistep reaction;
tert-butyl 3-bromopropionate
55666-43-8

tert-butyl 3-bromopropionate

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

3-(4-ethyl-2,3-dioxo-piperazin-1-yl)propionic acid tert-butyl ester
610311-90-5

3-(4-ethyl-2,3-dioxo-piperazin-1-yl)propionic acid tert-butyl ester

Conditions
ConditionsYield
With polystyrene-bound 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine In acetonitrile at 22℃; for 16h; Polystyrene;
[2-(4-(bromomethyl)phenyl)ethyl]carbamic acid tert-butyl ester
914103-95-0

[2-(4-(bromomethyl)phenyl)ethyl]carbamic acid tert-butyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

1-[4-(2-aminoethyl)benzyl]-4-ethylpiperazine-2,3-dione hydrochloride
914104-05-5

1-[4-(2-aminoethyl)benzyl]-4-ethylpiperazine-2,3-dione hydrochloride

Conditions
ConditionsYield
Stage #1: [2-(4-(bromomethyl)phenyl)ethyl]carbamic acid tert-butyl ester; 1-ethyl-2,3-dioxo-piperazine With sodium hydride In N,N-dimethyl-formamide at 1 - 30℃; for 1h;
Stage #2: With potassium hydrogensulfate; water; sodium hydrogencarbonate In ethyl acetate; N,N-dimethyl-formamide
Stage #3: With hydrogenchloride In ethyl acetate at 1 - 30℃; for 1h;
5-chloro-N-((1-(4-iodophenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide
945559-61-5

5-chloro-N-((1-(4-iodophenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

5-chloro-N-((1-(4-(4-ethyl-2,3-dioxopiperazin-1-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

5-chloro-N-((1-(4-(4-ethyl-2,3-dioxopiperazin-1-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Conditions
ConditionsYield
With potassium carbonate; N,N`-dimethylethylenediamine; copper(l) iodide In 1,4-dioxane; dimethyl sulfoxide at 110℃;
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

(4-ethyl-2, 3-dioxo-piperazin-1-yl)-acetic acid
488846-73-7

(4-ethyl-2, 3-dioxo-piperazin-1-yl)-acetic acid

Conditions
ConditionsYield
With potassium carbonate In tert-butyl alcohol
phosgene
75-44-5

phosgene

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
59703-00-3

4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride

Conditions
ConditionsYield
With chloro-trimethyl-silane; triethylamine In tetrahydrofuran; 1,4-dioxane
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

sodium 4-ethyl-2,3-dioxopiperazine

sodium 4-ethyl-2,3-dioxopiperazine

Conditions
ConditionsYield
With 1H-imidazole; sodium In 1,2-dimethoxyethane for 10h; Solvent; Reagent/catalyst; Reflux; Industrial scale;
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

(4-ethyl-2, 3-dioxo-piperazin-1-yl)-acetic acid
488846-73-7

(4-ethyl-2, 3-dioxo-piperazin-1-yl)-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C
View Scheme
bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

tert-butyl 2-(4-ethyl-2,3-dioxopiperazin-1-yl)acetate

tert-butyl 2-(4-ethyl-2,3-dioxopiperazin-1-yl)acetate

Conditions
ConditionsYield
Stage #1: 1-ethyl-2,3-dioxo-piperazine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Inert atmosphere;
Stage #2: bromoacetic acid tert-butyl ester In N,N-dimethyl-formamide; mineral oil at 20℃; for 3h; Inert atmosphere;
940 mg
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: dichloromethane / 0.5 h / 5 °C
2.1: 0.1 h / 8 °C / 1500.15 Torr / Inert atmosphere
3.1: dichloromethane
3.2: 0.67 h / 3 °C
4.1: water / 0.67 h / 6 - 9 °C / Large scale
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C26H35N5O7SSi

C26H35N5O7SSi

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: dichloromethane / 0.5 h / 5 °C
2.1: 0.1 h / 8 °C / 1500.15 Torr / Inert atmosphere
3.1: dichloromethane
3.2: 0.67 h / 3 °C
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C10H17ClN2O3Si

C10H17ClN2O3Si

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dichloromethane / 0.5 h / 5 °C
2: 0.1 h / 8 °C / 1500.15 Torr / Inert atmosphere
View Scheme
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C9H18N2O2Si

C9H18N2O2Si

Conditions
ConditionsYield
In dichloromethane at 5℃; for 0.5h;
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester
30925-18-9

2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

benzyl (S)-2-((tert-butoxycarbonyl)amino)-4-(ethyl-2,3-dioxopiperazin-1-yl)-4-oxobutanoate

benzyl (S)-2-((tert-butoxycarbonyl)amino)-4-(ethyl-2,3-dioxopiperazin-1-yl)-4-oxobutanoate

Conditions
ConditionsYield
Stage #1: 2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester With triethylamine; HATU In dichloromethane at 20℃; for 0.5h;
Stage #2: 1-ethyl-2,3-dioxo-piperazine In dichloromethane at 20℃; for 1h;
5.64 g
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester
30925-18-9

2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

(S)-2-((tert-butoxycarbonyl)amino)-4-(4-ethyl-2,3-dioxopiperazin-1-yl)-4-oxobutanoic acid

(S)-2-((tert-butoxycarbonyl)amino)-4-(4-ethyl-2,3-dioxopiperazin-1-yl)-4-oxobutanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: HATU; triethylamine / dichloromethane / 0.5 h / 20 °C
1.2: 1 h / 20 °C
2.1: hydrogen; palladium 10% on activated carbon / ethyl acetate / 18 h / 20 °C
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C15H12(2)H5N3O5

C15H12(2)H5N3O5

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
1.2: -30 °C / Inert atmosphere; Schlenk technique
2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.2: 1.5 h / -40 - 0 °C / Inert atmosphere; Schlenk technique
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

C30H28(2)H5N5O7S

C30H28(2)H5N5O7S

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
1.2: -30 °C / Inert atmosphere; Schlenk technique
2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.2: 1.5 h / -40 - 0 °C / Inert atmosphere; Schlenk technique
3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere; Schlenk technique
3.2: 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

A

C34H39(2)H5N6O7S

C34H39(2)H5N6O7S

B

C34H39(2)H5N6O7S

C34H39(2)H5N6O7S

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
1.2: -30 °C / Inert atmosphere; Schlenk technique
2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.2: 1.5 h / -40 - 0 °C / Inert atmosphere; Schlenk technique
3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere; Schlenk technique
3.2: 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
4.1: acetonitrile / 2 h / 20 °C / Inert atmosphere; Schlenk technique
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

piperacillin-D5

piperacillin-D5

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
1.2: -30 °C / Inert atmosphere; Schlenk technique
2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.2: 1.5 h / -40 - 0 °C / Inert atmosphere; Schlenk technique
3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere; Schlenk technique
3.2: 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
4.1: palladium on activated carbon; hydrogen / tetrahydrofuran; water / 1 h / 20 °C / 760.05 Torr / Schlenk technique
View Scheme
1-ethyl-2,3-dioxo-piperazine
59702-31-7

1-ethyl-2,3-dioxo-piperazine

A

C27H33(2)H5N6O7S

C27H33(2)H5N6O7S

B

C27H33(2)H5N6O7S

C27H33(2)H5N6O7S

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
1.2: -30 °C / Inert atmosphere; Schlenk technique
2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.2: 1.5 h / -40 - 0 °C / Inert atmosphere; Schlenk technique
3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere; Schlenk technique
3.2: 3 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
4.1: acetonitrile / 2 h / 20 °C / Inert atmosphere; Schlenk technique
5.1: palladium on activated carbon; hydrogen / tetrahydrofuran; water / 1 h / 20 °C / 760.05 Torr / Schlenk technique
View Scheme

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View