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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Benzo[b]thiophen-10-methoxycycloheptanone Manufacturer/High quality/Best price/In stock

Cas:59743-84-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-B]Thiophen-4-One supplier in China

Cas:59743-84-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

Ketotifen Fumarate[CAS:34580-14-8] 10-Methoxy-4H-benzo[4,5]cycloheta[1,2-b]thiophen-4-one[CAS:59743-84-9] HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture.

Benzo[b]thiophen-10-methoxycycloheptanone for Ketotifen

Cas:59743-84-9

Min.Order:1 Kilogram

Negotiable

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

Cas:59743-84-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Storage:2-8°C Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:shanghai

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one Cas no.59743-84-9 98%

Cas:59743-84-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Benzo[b]thiophen-10-methoxycycloheptanone_

Cas:59743-84-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

HotCAS 59743-84-9 with best quality

Cas:59743-84-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

59743-84-9 Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Benzo[b]thiophen-10-methoxycycloheptanone CAS:59743-84-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in hig

Benzo[b]thiophen-10-methoxycycloheptanone CAS:59743-84-9

Cas:59743-84-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4H-Benzo[4,5]cyclohepta[1,2-b]thiophen-4-one,10-methoxy-

Cas:59743-84-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4H-Benzo[4,5]cyclohepta[1,2-b]thiophen-4-one,10-methoxy-

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-B]Thiophen-4-One

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Manufacturers

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

BENZO[B]THIOPHEN-10-METHOXYCYCLOHEPTANONE

Cas:59743-84-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-B]Thiophen-4-One

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-B]Thiophen-4-One

Cas:59743-84-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystals powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermedi

Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-b]Thiophen-4-One CAS No.: 59743-84-9 Molecule Formula:C14H10O2S Molecule Weight:242.29 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard

Lower Price 10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-b]Thiophen-4-One in stock

Cas:59743-84-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

Product Name: Benzo[b]thiophen-10-methoxycycloheptanone Synonyms: BENZOTHIOPHEN-10-METHOXY-CYCLOHEPTANONE;10-Methoxy-4-Benzo[4,5]Cyclohepta[1,2-B]Thi…Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:aluminum foil bag,carton

Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--59743-84-9--Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Maytime Bio-Tech Co.,Ltd.

1.Strong synthesis team and service team. 2.Professional data management system. 3.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/GC,MS,COA,SDS 4.(2000+Suppliers) Partners.Any inquiries will be re

10-Methoxy-4-Benzo[4,5]Cyclohepta[1,2-B]Thiophene-4-One

Cas:59743-84-9

Min.Order:100 Kilogram

Negotiable

Type:Other

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFUCHEM--59743-84-9--Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--59743-84-9--Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Benzothiophen-10-methoxy-cycloheptanone

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--59743-84-9--Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-one

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

10-Methoxy-4H-Benzo(4,5)Cyclohepta(1,2-B)Thiophen-4-One

Cas:59743-84-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Benzo[b]thiophen-10-methoxycycloheptanone

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

10-Methoxy-4H-Benzo[4,5]Cycloheta[1,2-B]Thiophen-4-One

Cas:59743-84-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

methanol
67-56-1

methanol

9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one
34580-10-4

9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

Conditions
ConditionsYield
Stage #1: methanol; 9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one In water for 4h; Reflux;
Stage #2: With K2O/MgO In water for 4h; Reagent/catalyst; Reflux;
59.59%
9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one
34580-10-4

9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

A

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

B

9-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene4-one
126939-24-0

9-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene4-one

Conditions
ConditionsYield
mother liquors after XXIV diluted warwe and extracted with dichlormethane; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
9,10-dihydro-4H-4-oxobenzo<4,5>cyclohepta<1,2-b>thiophene
1622-55-5

9,10-dihydro-4H-4-oxobenzo<4,5>cyclohepta<1,2-b>thiophene

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-bromosuccinimide, dibenzyl peroxide / CCl4 / 3 h / Heating; alkaline mother methanolic liquor after XXII was diluted with water and extracted dichlormethane
2: mother liquors after XXIV diluted warwe and extracted with dichlormethane
View Scheme
methanol
67-56-1

methanol

C13H6Br2OS

C13H6Br2OS

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

Conditions
ConditionsYield
Stage #1: methanol; C13H6Br2OS for 7h; Reflux;
Stage #2: With potassium hydroxide for 3h; Reflux;
25.8 g
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene
60587-37-3

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene

Conditions
ConditionsYield
With lithium aluminium tetrahydride; aluminium trichloride In tetrahydrofuran; diethyl ether for 0.5h; Heating; reagents was added at 5 deg C;85%
aluminium chloride
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

(1-methyl-4-piperidyl)magnesium chloride
63463-36-5

(1-methyl-4-piperidyl)magnesium chloride

10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-4-ol
59743-88-3, 116655-77-7, 116667-71-1

10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-4-ol

Conditions
ConditionsYield
With tetrahydrofuran
4-chloro-1-methylpiperidine
5570-77-4

4-chloro-1-methylpiperidine

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-4-ol
59743-88-3, 116655-77-7, 116667-71-1

10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-4-ol

Conditions
ConditionsYield
With magnesium 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.; Yield given. Multistep reaction;
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-Bromotetrahydrothiopyran
32358-88-6

4-Bromotetrahydrothiopyran

A

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol

B

4-(4-tetrahydrothiopyranyl)-10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol
124939-82-8

4-(4-tetrahydrothiopyranyl)-10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol

C

4,4'-bis(tetrahydrothiopyranyl)
116196-83-9

4,4'-bis(tetrahydrothiopyranyl)

Conditions
ConditionsYield
With magnesium 1)preparation of Grignard reagent in ether, THF 2)5 deg C 3)1h, 5 deg C, 3h room temp.; Yield given. Multistep reaction. Yields of byproduct given;
With magnesium 1)ether, THF, 5 deg C 2)1h, 5 deg C, 3h room temp.; Yield given. Multistep reaction. Yields of byproduct given;
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

A

[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]-acetic acid methyl ester
98320-26-4

[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]-acetic acid methyl ester

B

methyl (10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-ylidene)acetate
98320-27-5

methyl (10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-ylidene)acetate

Conditions
ConditionsYield
With sodium hydride 1) paraffin oil, DMSO, 30 min. r.t., 2) DMF, 90 deg C, 15 h; Yield given. Multistep reaction. Yields of byproduct given;
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

ketotifen
34580-13-7

ketotifen

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mg / 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.
2: 97 percent / HCl / H2O / 1 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: THF
2: aq. HCl / 1 h / 100 °C
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

2-(1-methyl-4-hydroxy-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one
103825-68-9

2-(1-methyl-4-hydroxy-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium, hydrochloric acid / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then hydrochloric acid
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

10-methoxy-2-(1-methyl-4-hydroxy-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophene
103825-67-8

10-methoxy-2-(1-methyl-4-hydroxy-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium or lithium diisopropylamide, ammonium chloride / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then aq. ammonium chloride
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

9-bromo-10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol
126939-28-4

9-bromo-10-methoxy-4-(1-methyl-4-piperidyl)-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mg / 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.
2: 49 percent / pyridine, Br2 / pyridine-d5; CHCl3 / 1)CHCl3, 1.5h 20 deg C 2)reflux
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

2-(1-methyl-4-piperylid-3-ene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one hydrochloride
103825-69-0

2-(1-methyl-4-piperylid-3-ene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium, hydrochloric acid / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then hydrochloric acid
3: 32 percent / 3N-hydrochloric acid / 1 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium or lithium diisopropylamide, ammonium chloride / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then aq. ammonium chloride
3: 90 percent / 3N-hydrochloric acid / 1.5 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

2-(1-methyl-4-piperylid-3-ene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one
103825-70-3

2-(1-methyl-4-piperylid-3-ene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-10-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium, hydrochloric acid / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then hydrochloric acid
3: 32 percent / 3N-hydrochloric acid / 1 h / Heating
4: 56 percent / sodium hydroxyde / methanol
View Scheme
Multi-step reaction with 4 steps
1: 85 percent / lithium aluminium hydride, aluminium chloride / tetrahydrofuran; diethyl ether / 0.5 h / Heating; reagents was added at 5 deg C
2: butyllithium or lithium diisopropylamide, ammonium chloride / 1) -10 deg C, 1 h 2) -50 deg C, 1 h, at room temp. overnight, then aq. ammonium chloride
3: 90 percent / 3N-hydrochloric acid / 1.5 h / Heating
4: 56 percent / sodium hydroxyde / methanol
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

(+)-(R)-4-(1-methyl-4-piperidylidene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-10-one
34580-13-7, 116655-74-4, 116655-75-5, 116655-76-6

(+)-(R)-4-(1-methyl-4-piperidylidene)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-10-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mg / 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.
2: 97 percent / HCl / H2O / 1 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mg / 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.
2: 97 percent / HCl / H2O / 1 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-4-piperidyl)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene
7427-74-9

4-(1-methyl-4-piperidyl)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mg / 1)Grignard reagent in THF 2)15 deg C, 50min, educt XXIV 3)1.5h room temp.
2: triethylsilane, BF3(g), K2CO3, HCl / 1)CH2Cl2,-35 deg C, 15min 2)3,5 h at 0 deg C 3)H2O, K2CO3 4)reflux, 1h, HCl
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

(Z)-<10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-yliden>essigsaeure
98320-24-2

(Z)-<10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-yliden>essigsaeure

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1) NaH / 1) paraffin oil, DMSO, 30 min. r.t., 2) DMF, 90 deg C, 15 h
2: 71 percent / 2N NaOH / ethanol / 4 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

(E)-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)acetic acid
98320-25-3

(E)-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1) NaH / 1) paraffin oil, DMSO, 30 min. r.t., 2) DMF, 90 deg C, 15 h
2: 76 percent / 2N NaOH / ethanol / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-piperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione
43076-16-0

4-(1-methyl-piperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-9,10-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: SeO2 / acetic acid / 0.5 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-hydroxy-4-(1-methyl-4-piperidyl)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-10-one
126939-27-3, 137731-93-2, 137731-94-3

4-hydroxy-4-(1-methyl-4-piperidyl)-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiopene-10-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: THF
2: tartaric acid / H2O / 1 h / 90 °C
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-benzyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
43076-17-1

4-(1-benzyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: toluene
4: aq. H2SO4 / butan-1-ol / 16 h / Heating
5: Na2CO3 / hexamethylphosphoric acid triamide / 18 h / Ambient temperature
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-piperidin-4-ylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-ol
43076-12-6

4-(1-methyl-piperidin-4-ylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: NaBH4 / aq. ethanol / 42 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(10-oxo-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)piperidine
34580-20-6

4-(10-oxo-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)piperidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: toluene
4: aq. H2SO4 / butan-1-ol / 16 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (Z)-oxime
59743-93-0

4-(1-methyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (Z)-oxime

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: NH2OH*HCl, Py / 10 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (E)-oxime
59743-92-9

4-(1-methyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (E)-oxime

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: NH2OH*HCl / H2O / 1 h / 90 °C
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

N-ethoxyformylnorketotifen
34580-19-3

N-ethoxyformylnorketotifen

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: toluene
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

4-(1-methyl-1-oxy-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
88456-70-6, 137731-91-0, 137731-92-1

4-(1-methyl-1-oxy-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: THF
2: aq. HCl / 1 h / 100 °C
3: aq. H2O2 / ethanol / 48 h / Heating
View Scheme
10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one
59743-84-9

10-methoxy-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

ethoxycarbonylmethylen-diethylphosphonate [(C2 H5 O)2 POCH2 COOC2 H5 ]

ethoxycarbonylmethylen-diethylphosphonate [(C2 H5 O)2 POCH2 COOC2 H5 ]

water
7732-18-5

water

[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]-acetic acid ethyl ester

[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]-acetic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride; NaH In N-methyl-acetamide; dimethyl sulfoxide; ethyl acetate

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