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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shandong Xinhua Pharmaceutical Co.,Ltd

pharmaceutical intermediates Application:pharmaceutical intermediates

Trimethyl Phosphonoacetate

Cas:5927-18-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Trimethyl Phosphoroacetate?? supplier in China

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name rimethyl phosphonoacetate CAS No.

rimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

Trimethyl Phosphonoacetate

Cas:5927-18-4

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Trimethyl Phosphoroacetate

Cas:5927-18-4

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Trimethyl Phosphonoacetate-

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5927-18-4 with competitive price

Cas:5927-18-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Trimethyl phosphonoacetate/ LIDE PHARMA- Factory supply / Best price

Cas:5927-18-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Trimethyl phosphonoacetate CAS5927-18-4

Cas:5927-18-4

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Trimethyl phosphonoacetate Synonyms: methyl (dimethoxyphosphoryl)acetate CAS: 5927-18-4 MF: C5H11O5P Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Organic synthesis T

Trimethyl phosphonoacetate CAS: 5927-18-4

Cas:5927-18-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

TriMethyl phosphonoacetatCAS NO.:5927-18-4

Cas:5927-18-4

Min.Order:1 Gram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Aceticacid, 2-(dimethoxyphosphinyl)-, methyl ester 5927-18-4

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Trimethyl phosphonoacetate CAS: 5927-18-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

Trimethyl phosphonoacetate CAS: 5927-18-4

Cas:5927-18-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

Trimethyl phosphonoacetate supplier in China in stock CAS NO.5927-18-4

Cas:5927-18-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Trimethyl Phosphoroacetate

Cas:5927-18-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Methyl 2-(dimethoxyphosphoryl)acetate

Cas:5927-18-4

Min.Order:1 Kilogram

FOB Price: $6.0 / 10.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

RIMETHYL PHOSPHONOACETATE

Cas:5927-18-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Hot Sale 5927-18-4 Trimethyl phosphonoacetate supplier in China

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Trimethyl Phosphonoacetate CAS No.:5927-18-4 Molecule Formula:C5H11O5P Molecule Weight:182.11 Purity: 98.0% Package: 200kg/drum Description:Clear colorless to light yellow liquid Manufacture Standards:Enterprise Standard

High Quality Trimethyl Phosphonoacetate

Cas:5927-18-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Trimethylphosphonoacetate

Cas:5927-18-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Trimethyl phosphonoacetate Chemical Properties Melting point 242 °C Boiling point 118 °C0.85 mm Hg(lit.) density 1.125 g/mL at 25 °C(lit.) refractive index n20/D 1.437(lit.) Fp >230 °F storage temp. Store be

Trimethyl phosphonoacetate

Cas:5927-18-4

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate
88738-78-7

bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate

A

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

B

methyl methyl(2,2,2-trifluoroethyl)phosphonoacetate
681123-85-3

methyl methyl(2,2,2-trifluoroethyl)phosphonoacetate

Conditions
ConditionsYield
With triethylamine at 20℃; for 0.5h;A 7%
B 88%
bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
at 100℃; for 12h;74%
methyl chloroacetate
96-34-4

methyl chloroacetate

phosphorous acid trimethyl ester
121-45-9

phosphorous acid trimethyl ester

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
Heating;70%
methyl diazoacetate
6832-16-2

methyl diazoacetate

Dimethyl phosphite
868-85-9

Dimethyl phosphite

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
With copper acetylacetonate In benzene Heating;60%
methanol
67-56-1

methanol

ethyl diphenylphosphonoacetate
16139-79-0

ethyl diphenylphosphonoacetate

A

ethyl 2-(dimethoxyphosphoryl)acetate
311-46-6

ethyl 2-(dimethoxyphosphoryl)acetate

B

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

C

methyl methylphenylphosphonoacetate
625396-69-2

methyl methylphenylphosphonoacetate

D

ethyl methylphenylphosphonoacetate
625396-71-6, 852573-54-7

ethyl methylphenylphosphonoacetate

Conditions
ConditionsYield
With sodium hydroxide at 20℃; for 0.666667h;A 2%
B 13%
C 32%
D 7%
methanol
67-56-1

methanol

phosphonoacetic acid
4408-78-0

phosphonoacetic acid

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
(i) PCl5, (ii) /BRN= 1098229/, Et3N; Multistep reaction;
methanol
67-56-1

methanol

(2-chloro-2-ethoxy-vinyl)-phosphonic acid dichloride
42451-44-5

(2-chloro-2-ethoxy-vinyl)-phosphonic acid dichloride

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
In diethyl ether
methyl chloroacetate
96-34-4

methyl chloroacetate

Dimethyl phosphite
868-85-9

Dimethyl phosphite

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Conditions
ConditionsYield
With potassium carbonate at 20 - 30℃;
2-methylnicotinaldehyde
60032-57-7

2-methylnicotinaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl (E)/(Z)-3-(2-methyl-3-pyridyl)propenoate
137146-28-2, 137146-29-3

methyl (E)/(Z)-3-(2-methyl-3-pyridyl)propenoate

Conditions
ConditionsYield
With potassium carbonate In water for 4h; Ambient temperature;100%
2-methylbut-2-enal
497-03-0

2-methylbut-2-enal

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl (2E,4E)-4-methyl-2,4-hexadienoate
57258-50-1

methyl (2E,4E)-4-methyl-2,4-hexadienoate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In benzene at 20℃; for 1.33333h;
Stage #2: 2-methylbut-2-enal In benzene for 0.5h; Heating;
100%
With sodium hydride 1.) THF, 2.) RT, 9 h; Multistep reaction;
With sodium hydride In benzene at 65℃; for 4h;37.82 g
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

1,3-Diphenylpropanone

1,3-Diphenylpropanone

4-Phenyl-3-(phenylmethyl)-2-butenoic acid methyl ester
157731-51-6

4-Phenyl-3-(phenylmethyl)-2-butenoic acid methyl ester

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium In diethyl ether; hexane 1.) -20 deg C, 20 min, 2.) r.t., 50 h;100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

3-(4-methoxy-phenyl)acrylic acid methyl ester
3901-07-3

3-(4-methoxy-phenyl)acrylic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Metallation;
Stage #2: 4-methoxy-benzaldehyde In tetrahydrofuran; hexane at -78 - 20℃; Condensation; Horner-Wadsworth-Emmons reaction;
100%
Stage #1: trimethyl phosphonoacetate With n-butyllithium In tetrahydrofuran at -78℃;
Stage #2: 4-methoxy-benzaldehyde In tetrahydrofuran at -78 - 20℃; Horner-Wadsworth-Emmons reaction;
In tetrahydrofuran; hexane for 1h; Horner-Wadsworth-Emmons Olefination; Cooling with ice;
furfural
98-01-1

furfural

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl 3-(2-furyl)acrylate
58293-85-9

methyl 3-(2-furyl)acrylate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0℃;100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0℃; Metallation;
Stage #2: furfural In tetrahydrofuran for 0.166667h; Condensation;
90%
With 2,8,9-tris(2-methylpropyl)-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane In tetrahydrofuran at 20℃; for 2.2h; Inert atmosphere; optical yield given as %de; stereoselective reaction;84%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl 2-(bis((trimethylsilyl)oxy)phosphoryl)acetate
67605-34-9

methyl 2-(bis((trimethylsilyl)oxy)phosphoryl)acetate

Conditions
ConditionsYield
at 80℃; for 96h; Inert atmosphere;100%
In chlorobenzene at 130℃; for 8h;
at 80℃; for 96h; Inert atmosphere;
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

(1S,3aS,5S,7aR)-3a-hydroxy-5-cyclohexyl-7a-methylperhydroindene-1-carboxaldehyde
178379-71-0

(1S,3aS,5S,7aR)-3a-hydroxy-5-cyclohexyl-7a-methylperhydroindene-1-carboxaldehyde

methyl (1R,3aS,5S,7aR)-5-cyclohexyl-3a-hydroxy-7a-methylperhydroindene-1-yl-(E)-acrylate
392235-25-5

methyl (1R,3aS,5S,7aR)-5-cyclohexyl-3a-hydroxy-7a-methylperhydroindene-1-yl-(E)-acrylate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: (1S,3aS,5S,7aR)-3a-hydroxy-5-cyclohexyl-7a-methylperhydroindene-1-carboxaldehyde In tetrahydrofuran at 20℃; for 2h; Horner-Emmons reaction; Further stages.;
100%
3-Quinuclidinone
3731-38-2

3-Quinuclidinone

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

2-(1-azabicyclo[2.2.2]oct-3-ylidene)acetic acid methyl ester
94764-01-9

2-(1-azabicyclo[2.2.2]oct-3-ylidene)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h; Wittig Olefination; Inert atmosphere;
Stage #2: 3-Quinuclidinone In tetrahydrofuran; mineral oil at 20℃; Wittig Olefination; Inert atmosphere;
100%
Stage #1: trimethyl phosphonoacetate With sodium In methanol at 0℃; for 1h;
Stage #2: 3-Quinuclidinone In methanol at 0℃; for 0.5h; Horner-Wadsworth-Emmons reaction;
Stage #3: In methanol at 50℃; for 18h;
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: 3-Quinuclidinone In tetrahydrofuran at 0 - 20℃; Wadsworth-Emmons reaction;
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h;
Stage #2: 3-Quinuclidinone In tetrahydrofuran; mineral oil at 20℃; for 18h;
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-(2-oxo-2-quinolin-3-yl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester
669075-94-9

4-(2-oxo-2-quinolin-3-yl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester

4-(3-methoxycarbonyl-2-quinolin-3-ylallyl)piperidine-1-carboxylic acid tert-butyl ester
669075-95-0

4-(3-methoxycarbonyl-2-quinolin-3-ylallyl)piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran for 4h; Heating;100%
furan-3-carboxaldehyde
498-60-2

furan-3-carboxaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

Methyl 3-(3'-furanyl)prop-2-en-1-oate
99595-62-7

Methyl 3-(3'-furanyl)prop-2-en-1-oate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0℃;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

3-Thiophen-3-yl-acrylic Acid Methyl Ester
75754-85-7

3-Thiophen-3-yl-acrylic Acid Methyl Ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0℃;100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran for 1h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 20℃; for 18h;
94%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 2h; Inert atmosphere;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 20℃; Inert atmosphere;
81%
3-(4-methoxyphenoxy)-3-perfluoropentyl-prop-2-enal

3-(4-methoxyphenoxy)-3-perfluoropentyl-prop-2-enal

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl (EE)-5-(4-methoxyphenoxy)-5-perfluoropentyl-2,4-pentadienoate

methyl (EE)-5-(4-methoxyphenoxy)-5-perfluoropentyl-2,4-pentadienoate

Conditions
ConditionsYield
With sodium hydride In methanol at 20℃; for 2h; Wadsworth-Emmons reaction;100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-Carboxybenzaldehyde
619-66-9

4-Carboxybenzaldehyde

methyl (E)-4-carboxyl cinnamate
115974-97-5

methyl (E)-4-carboxyl cinnamate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate; 4-Carboxybenzaldehyde With potassium carbonate In water at 0 - 20℃; for 1.5h;
Stage #2: In water pH=1; Acidic aqueous solution;
100%
With potassium carbonate In water at 0 - 20℃; pH=Ca. 2;95%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

m-formylphenyl benzoic acid
619-21-6

m-formylphenyl benzoic acid

(E)-3-(methoxy-3-oxoprop-1-en-1-yl)benzoic acid
115974-96-4

(E)-3-(methoxy-3-oxoprop-1-en-1-yl)benzoic acid

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate; m-formylphenyl benzoic acid With potassium carbonate In water at 0 - 20℃; for 17h;
Stage #2: In water pH=1; Acidic aqueous solution;
100%
With potassium carbonate In water at 0 - 20℃; pH=Ca. 2;93%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

2-ethoxy-4-nitro-benzaldehyde
1134-43-6

2-ethoxy-4-nitro-benzaldehyde

ethyl 4-nitro-2-ethoxycinnamate
863885-81-8

ethyl 4-nitro-2-ethoxycinnamate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 2-ethoxy-4-nitro-benzaldehyde In tetrahydrofuran at 20℃; for 4h; Wittig-Horner Reaction; Inert atmosphere;
100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0℃;
Stage #2: 2-ethoxy-4-nitro-benzaldehyde In tetrahydrofuran at 0 - 20℃; for 15h;
99%
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 15h;
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-(4-hydroxyphenyl)cyclohexan-1-one
105640-07-1

4-(4-hydroxyphenyl)cyclohexan-1-one

[4-(4-hydroxyphenyl)cyclohexylidene]acetic acid methyl ester
701232-66-8

[4-(4-hydroxyphenyl)cyclohexylidene]acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In mineral oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: 4-(4-hydroxyphenyl)cyclohexan-1-one In tetrahydrofuran; mineral oil at 20℃; for 0.416667h; Inert atmosphere;
100%
With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 2.83333h; Inert atmosphere;100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; Inert atmosphere;
Stage #2: 4-(4-hydroxyphenyl)cyclohexan-1-one In tetrahydrofuran; mineral oil at 25℃; for 5h;
97%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

(2R)-2-(1,1-dimethylethoxycarbonylamino)-2-cyclohexylethanal
171560-20-6

(2R)-2-(1,1-dimethylethoxycarbonylamino)-2-cyclohexylethanal

(R)-4-tert-butoxycarbonylamino-4-cyclohexyl-but-2-enoic acid methyl ester
876761-53-4

(R)-4-tert-butoxycarbonylamino-4-cyclohexyl-but-2-enoic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 5℃; for 1h; Inert atmosphere;
Stage #2: (2R)-2-(1,1-dimethylethoxycarbonylamino)-2-cyclohexylethanal In tetrahydrofuran; mineral oil at 0 - 20℃;
100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.5h;
Stage #2: (2R)-2-(1,1-dimethylethoxycarbonylamino)-2-cyclohexylethanal In tetrahydrofuran at 0 - 20℃; for 0.333333h;
p-benzyloxybenzaldehyde
4397-53-9

p-benzyloxybenzaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

(E)-methyl 3-(4-(benzyloxy)phenyl)acrylate
84184-51-0

(E)-methyl 3-(4-(benzyloxy)phenyl)acrylate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 0℃;
Stage #2: p-benzyloxybenzaldehyde In tetrahydrofuran; mineral oil at 20℃;
100%
pyridine-4-carbaldehyde
872-85-5

pyridine-4-carbaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

(E)-methyl 3-(pyridine-4-yl)prop-2-enoate
81124-49-4

(E)-methyl 3-(pyridine-4-yl)prop-2-enoate

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 0 - 20℃; for 5h;100%
tert-butoxycarbonylamino-[4-(4-formylphenoxy)-phenyl]-acetic acid
918337-11-8

tert-butoxycarbonylamino-[4-(4-formylphenoxy)-phenyl]-acetic acid

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

3-{4-[4-(tert-butoxycarbonylaminocarboxymethyl)-phenoxy]-phenyl}-acrylic acid methyl ester
918337-12-9

3-{4-[4-(tert-butoxycarbonylaminocarboxymethyl)-phenoxy]-phenyl}-acrylic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0 - 5℃; for 0.0833333h;
Stage #2: tert-butoxycarbonylamino-[4-(4-formylphenoxy)-phenyl]-acetic acid In tetrahydrofuran at 0 - 20℃; for 0.5h;
Stage #3: With hydrogenchloride; citric acid In tetrahydrofuran; water pH=~ 2;
100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

2-(trifluoromethoxy)benzaldehyde
94651-33-9

2-(trifluoromethoxy)benzaldehyde

methyl (2E)-3-[2-(trifluoromethoxy)phenyl]prop-2-enoate
1202578-19-5

methyl (2E)-3-[2-(trifluoromethoxy)phenyl]prop-2-enoate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran at 0℃; Inert atmosphere;
Stage #2: 2-(trifluoromethoxy)benzaldehyde In tetrahydrofuran at 20℃; Inert atmosphere;
100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

C13H19NO2

C13H19NO2

C16H23NO3

C16H23NO3

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; Horner-Wadsworth-Emmons Olefination;100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

2-methylphenyl aldehyde
529-20-4

2-methylphenyl aldehyde

methyl (E)-3-(2-methylphenyl)-2-propenoate
70625-62-6, 75950-75-3, 130451-86-4

methyl (E)-3-(2-methylphenyl)-2-propenoate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: 2-methylphenyl aldehyde In tetrahydrofuran; paraffin oil at -78 - 20℃; Inert atmosphere;
100%
With sodium methylate In methanol; N,N-dimethyl-formamide Wittig-Horner Reaction;
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester
101385-93-7

3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(2-methoxy-2-oxoethylidene)pyrrolidine-1-carboxylate
441773-67-7

tert-butyl 3-(2-methoxy-2-oxoethylidene)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.333333h;
Stage #2: 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester In tetrahydrofuran; mineral oil at 0 - 20℃; for 16h;
100%
Stage #1: trimethyl phosphonoacetate With potassium tert-butylate In tetrahydrofuran at 0℃; for 2.5h;
Stage #2: 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester In tetrahydrofuran at 0℃; for 1h;
92.8%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

m-tolyl aldehyde
620-23-5

m-tolyl aldehyde

(E)-methyl 3-methylcinnamate
82444-40-4, 118315-74-5, 95416-56-1

(E)-methyl 3-methylcinnamate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: m-tolyl aldehyde In tetrahydrofuran; paraffin oil at -78 - 20℃; Inert atmosphere;
100%
piperonal
120-57-0

piperonal

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

methyl (2E)-3-(1,3-benzodioxol-5-yl)acrylate
40918-96-5

methyl (2E)-3-(1,3-benzodioxol-5-yl)acrylate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: piperonal In tetrahydrofuran; paraffin oil at -78 - 20℃; Inert atmosphere;
100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

3-p-tolyl-acrylic acid methyl ester
20754-20-5

3-p-tolyl-acrylic acid methyl ester

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: 4-methyl-benzaldehyde In tetrahydrofuran; paraffin oil at -78 - 20℃; Inert atmosphere;
100%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

2-(8-phenyloctyl) benzaldehyde
96964-45-3

2-(8-phenyloctyl) benzaldehyde

methyl 3-<2-(8-phenyloctyl)phenyl>propenoate
145950-31-8

methyl 3-<2-(8-phenyloctyl)phenyl>propenoate

Conditions
ConditionsYield
99%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

(2S,3S)-3-(tert-Butyl-diphenyl-silanyl)-oxirane-2-carbaldehyde
178391-54-3

(2S,3S)-3-(tert-Butyl-diphenyl-silanyl)-oxirane-2-carbaldehyde

(E)-3-[(2S,3S)-3-(tert-Butyl-diphenyl-silanyl)-oxiranyl]-acrylic acid methyl ester

(E)-3-[(2S,3S)-3-(tert-Butyl-diphenyl-silanyl)-oxiranyl]-acrylic acid methyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride In acetonitrile for 0.5h; Ambient temperature;99%
trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

4-methoxy-1-naphthaldehyde
15971-29-6

4-methoxy-1-naphthaldehyde

methyl-3-(4-methoxy-1-naphthyl)-E-propenoate

methyl-3-(4-methoxy-1-naphthyl)-E-propenoate

Conditions
ConditionsYield
Stage #1: trimethyl phosphonoacetate With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 0.25h;
Stage #2: 4-methoxy-1-naphthaldehyde In dichloromethane at 20℃; for 36h;
99%
Stage #1: trimethyl phosphonoacetate With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 0.25h;
Stage #2: 4-methoxy-1-naphthaldehyde In dichloromethane at 0 - 20℃; for 36h;
99%
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h; Horner-Wadsworth-Emmons reaction;89%
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