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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Thiophenecarboxaldehyde Manufacturer/High quality/Best price/In stock

Cas:498-62-4

Min.Order:1 Kilogram

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Thiophene Carboxaldehyde supplier in China

Cas:498-62-4

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Henan Allgreen Chemical Co.,Ltd

Good price Good quality Promptly delivery Appearance:powder Storage:dry condition Package:According to the demand of customer Application:intermediate Transportation:By sea or by air Port:Shanghai Port

498-62-4,3-Thiophenecarboxaldehyde

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-Thiophene Carboxaldehyde

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-Thiophenecarboxaldehyde

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

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Hebei yanxi chemical co.,LTD.

1 Factory price 2 Good service 3 High quality 4 Prompt delivery chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pha

Thiophene-3-carboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

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Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM 3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 3-Thiophenecarboxaldehyde CAS No. 498-62-4

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Metric Ton

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

top quality 3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 498-62-4 with best quality

Cas:498-62-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Thiophenecarboxaldehyde 498-62-4

Cas:498-62-4

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Shanghai Minstar Chemical Co., Ltd

3-Thiophenecarboxaldehyde Chemical Properties Melting point -30 °C Boiling point 194-196 °C (lit.) 86-87 °C/20 mmHg (lit.) density 1.28 g/mL at 25 °C (lit.) vapor pressure 0.31 mm Hg ( 20 °C) refractive index n

3-Thiophenecarboxaldehyde.

Cas:498-62-4

Min.Order:1 Gram

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Qingdao Beluga Import and Export Co., LTD

3-Thiophenecarboxaldehyde CAS:498-62-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

3-Thiophenecarboxaldehyde CAS:498-62-4

Cas:498-62-4

Min.Order:1 Gram

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-Thiophenecarboxaldehyde

Cas:498-62-4

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3-Thiophene Carboxaldehyde

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Triumph International Development Limilted

Product name: sodium metabisulfite / sodium metabisulphite Molecular weight: 190.10 Specification: 25Kg woven bag Quality guarantee period: 6 months Appearance:clear yellow to light brown liquid Storage:kept in a cool, dry and vent

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:10 Gram

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3-THIOPHENECARBOXALDEHYDE

Cas:498-62-4

Min.Order:1 Gram

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Thiophenecarboxaldehyde

Cas:498-62-4

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

thiophene-3-carbaldehyde

Cas:498-62-4

Min.Order:4 Kilogram

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Gram

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Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Gram

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:10 Gram

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Siwei Development Group Ltd.

Product name: 3-Thenaldehyde CAS No.:498-62-4 Molecule Formula:C5H4OS Molecule Weight:112.15 Purity: 99.0% Package: 25kg/drum Description:Colorless to light yellow transparent liquid Manufacture Standards:Enterprise Standard TEST

Best Quality 3-Thenaldehyde

Cas:498-62-4

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Top sale 498-62-4 3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-Thiophenecarboxaldehyde

Cas:498-62-4

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Top sale 498-62-4 3-Thiophenecarboxaldehyde

Cas:498-62-4

Min.Order:1 Gram

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Top sale 498-62-4 3-Thiophenecarboxaldehyde

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Synthetic route

3-hydroxymethyl-thiophene
71637-34-8

3-hydroxymethyl-thiophene

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With silica gel; 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate In dichloromethane Ambient temperature;96%
With oxygen In 1,3,5-trimethyl-benzene at 60℃; under 760.051 Torr; for 3h; Solvent; Reagent/catalyst;95%
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium nitrate; europium(III) nitrate hexahydrate; acetic acid In toluene at 40℃; for 9h;95%
2,5-dihydro-3-thiophenecarboxaldehyde
113772-16-0

2,5-dihydro-3-thiophenecarboxaldehyde

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With sulfuryl dichloride In dichloromethane at -36 - -30℃; for 0.5h;92%
With sulfuryl dichloride In dichloromethane at -35℃;58.9%
2-(thiophen-3-yl)-1,3-dithiane
1244041-07-3

2-(thiophen-3-yl)-1,3-dithiane

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With eosin y In water; acetonitrile at 20℃; for 3h; Irradiation;89%
3-Bromothiophene
872-31-1

3-Bromothiophene

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
Stage #1: 3-Bromothiophene With n-butyllithium In diethyl ether; hexane at -78℃; for 1h;
Stage #2: N,N-dimethyl-formamide In diethyl ether; hexane at -78 - 20℃; for 1.5h;
87.8%
Stage #1: 3-Bromothiophene With n-butyllithium In diethyl ether; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In diethyl ether; hexane at 20℃; for 12h; Inert atmosphere;
70%
3-hydroxymethyl-thiophene
71637-34-8

3-hydroxymethyl-thiophene

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

3-Thiophene carboxylic acid
88-13-1

3-Thiophene carboxylic acid

Conditions
ConditionsYield
With sodium hypochlorite; C8H18NPol; sodium hydrogencarbonate In water; toluene at 15 - 20℃; for 4.5h; Product distribution / selectivity;A 87.5%
B 0.1%
With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen In 1,2-dichloro-ethane at 25℃; for 48h; Schlenk technique;A 18 %Spectr.
B 65%
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate In water; toluene at 15 - 20℃; for 4.5h; Product distribution / selectivity;A 52.3%
B 2.3%
C17H28OS2

C17H28OS2

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With triethylsilane In tetrahydrofuran for 1h; Reagent/catalyst; Fukuyama Reduction;87%
3-thienyl iodide
10486-61-0

3-thienyl iodide

carbon monoxide
201230-82-2

carbon monoxide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With triethylsilane; palladium diacetate; sodium hydrogencarbonate; sodium carbonate at 20℃; under 760.051 Torr; for 48h;84%
With rhodium(III) chloride trihydrate; hydrogen; triethylamine; triphenylphosphine In N,N-dimethyl acetamide at 90℃; under 7500.75 Torr; for 12h; Autoclave;68%
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; formic acid In N,N-dimethyl-formamide at 50℃; under 760 Torr; for 5h; Electrolysis;82 % Chromat.
3-thienyl iodide
10486-61-0

3-thienyl iodide

formic acid
64-18-6

formic acid

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With palladium diacetate; triethylamine; dicyclohexyl-carbodiimide; tricyclohexylphosphine In N,N-dimethyl-formamide at 60℃; for 10h; Inert atmosphere; Sealed tube;84%
Stage #1: 3-thienyl iodide; formic acid With palladium diacetate; acetic anhydride; tricyclohexylphosphine In N,N-dimethyl-formamide at 30℃; for 1h; Inert atmosphere; Green chemistry;
Stage #2: With triethylamine In N,N-dimethyl-formamide at 80℃; for 6h; Inert atmosphere; Green chemistry;
65%
3-Bromothiophene
872-31-1

3-Bromothiophene

carbon monoxide
201230-82-2

carbon monoxide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With N,N,N,N,-tetramethylethylenediamine; hydrogen; palladium diacetate; propyl di-tert-butylphosphinite In toluene at 100℃; under 3750.38 Torr; for 20h; Inert atmosphere;82%
With 4-methoxy-N'-tetramethylethylenediamine; hydrogen; catacxium A; palladium diacetate In toluene at 100℃; under 3750.3 Torr; for 16h;82 % Chromat.
With N,N,N,N,-tetramethylethylenediamine; hydrogen; catacxium A; palladium diacetate In toluene at 100℃; under 3750.38 Torr; for 16h;82 % Chromat.
With N,N,N,N,-tetramethylethylenediamine; C6H6*C48H78O2P2Pd; hydrogen In toluene at 20 - 100℃; under 3750.38 Torr; Inert atmosphere; Autoclave;87 %Chromat.
3-thienyl iodide
10486-61-0

3-thienyl iodide

carbon dioxide
124-38-9

carbon dioxide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With dichloro [1,1'-bis(diphenylphosphino)propane]palladium(II); 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 80℃; under 7500.75 Torr; for 20h; Autoclave; Green chemistry;82%
With rhodium(III) iodide; hydrogen; acetic anhydride; triethylamine; triphenylphosphine In N,N-dimethyl acetamide at 100℃; for 24h; Autoclave;60%
(CH3CNO)2(CH3CNOH)2Co(C5H5N)(OOCH2C4H3S)

(CH3CNO)2(CH3CNOH)2Co(C5H5N)(OOCH2C4H3S)

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

3-hydroxymethyl-thiophene
71637-34-8

3-hydroxymethyl-thiophene

Conditions
ConditionsYield
In methanol decomposition of the complex by refluxing in methanol under N2 for 6-8 h; evapn. of the solvent, extn. of the organic compounds with ether, gas chromatography;A 19%
B 81%
3-Bromothiophene
872-31-1

3-Bromothiophene

carbon dioxide
124-38-9

carbon dioxide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With dichloro [1,1'-bis(diphenylphosphino)propane]palladium(II); 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 100℃; under 7500.75 Torr; for 20h; Autoclave; Green chemistry;80%
3-Bromothiophene
872-31-1

3-Bromothiophene

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With triethylsilane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium acetate In acetonitrile at 60℃; for 16h; Schlenk technique; Inert atmosphere;77%
3-Thiophene carboxylic acid
88-13-1

3-Thiophene carboxylic acid

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With palladium(II) acetylacetonate; hydrogen; 2,2-dimethylpropanoic anhydride; dicyclohexylphenylphosphine In tetrahydrofuran at 80℃; under 3750.38 Torr; for 20h; Inert atmosphere;70%
With hydrogen; 2,2-dimethylpropanoic anhydride; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 80℃; under 22501.8 Torr; for 48h;73 % Spectr.
Multi-step reaction with 2 steps
1: 88 percent / LiAlH4 / diethyl ether
2: 7.3 g / PCD / CH2Cl2 / 1.5 h
View Scheme
Multi-step reaction with 3 steps
1: thionyl chloride
2: pyridine
3: phosphorus (V)-chloride; benzene / anschliessend in Aether mit Zinn(II)-chlorid und Chlorwasserstoff behandeln und Erhitzen des vom Aether befreiten Reaktionsgemisches mit Wasser
View Scheme
3-Bromothiophene
872-31-1

3-Bromothiophene

3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide
50978-45-5

3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With triethylsilane; palladium diacetate; sodium carbonate; 1,4-di(diphenylphosphino)-butane In N,N-dimethyl-formamide at 80℃; Inert atmosphere; Sealed tube;70%
3-styryl-thiophene
35022-11-8

3-styryl-thiophene

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

naphtho[1,2-b]thiophene
234-41-3

naphtho[1,2-b]thiophene

C

benzaldehyde
100-52-7

benzaldehyde

D

[2,2']Bi[naphtho[1,2-b]thiophenyl]
78604-61-2

[2,2']Bi[naphtho[1,2-b]thiophenyl]

Conditions
ConditionsYield
With oxygen In hexane Cyclization; oxidation; Irradiation;A 8%
B 69%
C 8%
D 15%
With oxygen In hexane at 25℃; Cyclization; oxidation; Irradiation;A 8%
B 69%
C 8%
D 15%
1,4-dithiane-2,5-diol
40018-26-6

1,4-dithiane-2,5-diol

Malondialdehyde
542-78-9

Malondialdehyde

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With diethylamine at 70℃; for 6h; Temperature; Reagent/catalyst;65%
1-(thiophen-3-yl)-ethanone
1468-83-3

1-(thiophen-3-yl)-ethanone

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With copper(l) iodide; oxygen In dimethyl sulfoxide at 120℃; for 19h; chemoselective reaction;64%
3-thienyl iodide
10486-61-0

3-thienyl iodide

carbon dioxide
124-38-9

carbon dioxide

A

thiophene
188290-36-0

thiophene

B

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With palladium on activated charcoal; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 80℃; for 20h; Autoclave;A 27%
B 64%
3-Bromothiophene
872-31-1

3-Bromothiophene

formaldehyd
50-00-0

formaldehyd

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With triethylsilane; dichloro bis(acetonitrile) palladium(II); sodium carbonate; 1,4-di(diphenylphosphino)-butane In N,N-dimethyl-formamide at 20 - 100℃; under 15001.5 Torr; for 20h; Inert atmosphere; Autoclave;63%
C10H8OS2

C10H8OS2

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With sodium azide; copper(II) choride dihydrate; oxygen In N,N-dimethyl-formamide at 100℃; for 10h; Schlenk technique; Sealed tube;A 47%
B 53%
3-Bromomethylthiophene
34846-44-1

3-Bromomethylthiophene

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
28%
With chloroform; hexamethylenetetramine Erhitzen des Reaktionsprodukts mit Wasserdampf oder mit wss. Aethanol;
Multi-step reaction with 2 steps
1: chloroform
2: water / Heating
View Scheme
With 4-methylmorpholine N-oxide In ethyl acetate at 50℃; for 6h; Solvent;
1,4-dithiane-2,5-diol
40018-26-6

1,4-dithiane-2,5-diol

3-methoxyacrolein
4652-35-1

3-methoxyacrolein

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 10℃; for 2h;23%
3-formylthiophene diethyl acetal
3199-44-8

3-formylthiophene diethyl acetal

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

N-phenyl-3-thiophene-carboxamide
55797-29-0

N-phenyl-3-thiophene-carboxamide

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With phosphorus pentachloride; benzene anschliessend in Aether mit Zinn(II)-chlorid und Chlorwasserstoff behandeln und Erhitzen des vom Aether befreiten Reaktionsgemisches mit Wasser;
methyllithium
917-54-4

methyllithium

thieno(3,2-d) isoselenazole
76835-01-3

thieno(3,2-d) isoselenazole

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

2-Methylselanyl-thiophene-3-carbonitrile

2-Methylselanyl-thiophene-3-carbonitrile

C

C10H4N2S2Se

C10H4N2S2Se

D

2-Methylselanyl-thiophene-3-carbaldehyde
76834-96-3

2-Methylselanyl-thiophene-3-carbaldehyde

Conditions
ConditionsYield
With water In tetrahydrofuran; diethyl ether at -80℃; for 5h; Product distribution;A 16 % Chromat.
B 18 % Chromat.
C 26 % Chromat.
D 100 % Chromat.
(3-thienyl)diazomethane
120361-26-4

(3-thienyl)diazomethane

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Conditions
ConditionsYield
With oxygen In solid matrix at -233.2℃;
3-styryl-thiophene
35022-11-8

3-styryl-thiophene

A

3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

B

benzaldehyde
100-52-7

benzaldehyde

Conditions
ConditionsYield
With oxygen; 9,10-Dicyanoanthracene In acetonitrile at 25℃; for 3h; Oxidation; Irradiation;A 100 % Turnov.
B 100 % Turnov.
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(E)-3-thiophen-3-yl-acrylic acid ethyl ester
50266-60-9

(E)-3-thiophen-3-yl-acrylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 20℃; for 1h;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 0 - 20℃; for 3.25h;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With potassium tert-butylate In tetrahydrofuran at 20℃;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 90℃; for 0.5h;
90%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

O,O-diethyl benzylphosphonate
1080-32-6

O,O-diethyl benzylphosphonate

(E)-3-styrylthiophene
78347-97-4

(E)-3-styrylthiophene

Conditions
ConditionsYield
With sodium methylate In N,N-dimethyl-formamide at 0 - 20℃; for 1.75h;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

(R)-Phenylglycinol
56613-80-0

(R)-Phenylglycinol

(R)-2-Phenyl-2-{[1-thiophen-3-yl-meth-(E)-ylidene]-amino}-ethanol
139437-49-3

(R)-2-Phenyl-2-{[1-thiophen-3-yl-meth-(E)-ylidene]-amino}-ethanol

Conditions
ConditionsYield
With magnesium sulfate In dichloromethane at 20℃; for 12h;100%
In benzene Heating;92%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

benzylamine
100-46-9

benzylamine

N-benzylthiophene-3-carbaldehyde imine

N-benzylthiophene-3-carbaldehyde imine

Conditions
ConditionsYield
With aluminum oxide for 12h;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

trimethyl phosphonoacetate
5927-18-4

trimethyl phosphonoacetate

3-Thiophen-3-yl-acrylic Acid Methyl Ester
75754-85-7

3-Thiophen-3-yl-acrylic Acid Methyl Ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0℃;100%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran for 1h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 20℃; for 18h;
94%
Stage #1: trimethyl phosphonoacetate With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 2h; Inert atmosphere;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 20℃; Inert atmosphere;
81%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

(α-chloro-benzyl)-phosphonic acid diphenyl ester
58263-67-5

(α-chloro-benzyl)-phosphonic acid diphenyl ester

1-phenyl-2-(3-thienyl)ethyne
131423-29-5

1-phenyl-2-(3-thienyl)ethyne

Conditions
ConditionsYield
Stage #1: 3-thiophene carboxaldehyde; (α-chloro-benzyl)-phosphonic acid diphenyl ester With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h; Horner-Emmons reaction;
Stage #2: With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Horner-Emmons reaction; Further stages.;
100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

diphenyl chloro(4-methoxycarbonylphenyl)methylphosphonate
189099-53-4

diphenyl chloro(4-methoxycarbonylphenyl)methylphosphonate

1-(4-methoxyphenyl)-2-(3-thienyl)ethyne

1-(4-methoxyphenyl)-2-(3-thienyl)ethyne

Conditions
ConditionsYield
Stage #1: 3-thiophene carboxaldehyde; diphenyl chloro(4-methoxycarbonylphenyl)methylphosphonate With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h; Horner-Emmons reaction;
Stage #2: With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Horner-Emmons reaction; Further stages.;
100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

diphenyl phosphonate
54335-03-4

diphenyl phosphonate

C12H7NO3S

C12H7NO3S

Conditions
ConditionsYield
Stage #1: 3-thiophene carboxaldehyde; diphenyl phosphonate With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h; Horner-Emmons reaction;
Stage #2: With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Horner-Emmons reaction; Further stages.;
100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

Diphenyl 1-Chloro-1-(4-pyridyl)methanephosphonate
138517-18-7

Diphenyl 1-Chloro-1-(4-pyridyl)methanephosphonate

4-(thien-3-ylethynyl)pyridine

4-(thien-3-ylethynyl)pyridine

Conditions
ConditionsYield
Stage #1: 3-thiophene carboxaldehyde; diphenyl 1-chloro-1-(4-pirydyl)methanephosphonate With potassium tert-butylate In tetrahydrofuran at 20℃; for 3h; Horner-Emmons reaction;
Stage #2: With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Horner-Emmons reaction; Further stages.;
100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

3-thiophenecarbaldoxime hydrochloride

3-thiophenecarbaldoxime hydrochloride

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium hydroxide In ethanol; water at 20℃; for 18h;100%
With pyridine; hydroxylamine hydrochloride In ethanol at 20℃; for 2h;90%
With pyridine; hydroxylamine hydrochloride In ethanol at 20℃; for 2h;90%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl [(3-thienyl)methylene]malonate
1300690-47-4

dimethyl [(3-thienyl)methylene]malonate

Conditions
ConditionsYield
With piperidine; benzoic acid for 12h; Heating / reflux;100%
With piperidine; acetic acid In benzene for 4h; Reflux;96%
With piperidine; acetic acid In benzene Dean-Stark; Reflux;
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

4-phenyl-1-piperazine
92-54-6

4-phenyl-1-piperazine

1-phenyl-4-(thiophen-3-ylmethyl)piperazine
414887-78-8

1-phenyl-4-(thiophen-3-ylmethyl)piperazine

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 18℃; for 2h; Solvent; Green chemistry;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

(E)-2-(buta-1,3-dien-1-yl)aniline
138386-62-6

(E)-2-(buta-1,3-dien-1-yl)aniline

C15H13NS

C15H13NS

Conditions
ConditionsYield
In ethanol at 80℃; Inert atmosphere;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

3-thiophenecarboxaldehyde oxime
148134-23-0

3-thiophenecarboxaldehyde oxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride In pyridine; water; ethyl acetate99%
With hydroxylamine
With hydroxylamine hydrochloride; copper(II) sulfate at 90℃; for 2h;85 % Spectr.
With hydroxylamine In methanol
With sodium chloride; hydroxylamine hydrochloride; sodium carbonate In ethanol; water
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

1-(benzo[d][1,3]dioxol-6-yl)ethanone
3162-29-6

1-(benzo[d][1,3]dioxol-6-yl)ethanone

(E)-1-benzo[1,3]dioxol-5-yl-3-thiophen-3-ylpropenone

(E)-1-benzo[1,3]dioxol-5-yl-3-thiophen-3-ylpropenone

Conditions
ConditionsYield
Stage #1: 1-(benzo[d][1,3]dioxol-6-yl)ethanone With lithium hydroxide In ethanol at 20℃; for 0.166667h; Large scale;
Stage #2: 3-thiophene carboxaldehyde In ethanol at 20℃; Large scale;
99%
With sodium hydroxide In ethanol; water
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-(thiophen-3-yl)-3-(trimethylsilyl)prop-2-yn-1-ol
849769-14-8

1-(thiophen-3-yl)-3-(trimethylsilyl)prop-2-yn-1-ol

Conditions
ConditionsYield
Stage #1: trimethylsilylacetylene With n-butyllithium In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 0℃; for 1h;
99%
Stage #1: trimethylsilylacetylene With n-butyllithium In tetrahydrofuran at 0℃; for 1h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 0℃; for 1h;
95%
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 1h;
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

5-methyl-1H-indole
614-96-0

5-methyl-1H-indole

3,3'-bis-(5-methyl)-indolyl-3-thienylmethane

3,3'-bis-(5-methyl)-indolyl-3-thienylmethane

Conditions
ConditionsYield
With 1-hexyl-3-methylimidazolium hydrogen sulphate In ethanol at 20℃; for 1h;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

ethylene glycol
107-21-1

ethylene glycol

2-(thiophen-3-yl)-1,3-dioxolane
13250-82-3

2-(thiophen-3-yl)-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 165℃; for 6h;99%
With toluene-4-sulfonic acid In benzene Heating;97%
toluene-4-sulfonic acid In toluene for 4h; Heating / reflux;95.9%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

1-Heptylamine
111-68-2

1-Heptylamine

N-(3-thienylmethylene)-n-heptylamine

N-(3-thienylmethylene)-n-heptylamine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 3h; Heating;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

methylmagnesium bromide
75-16-1

methylmagnesium bromide

1-(thiophen-3-yl)ethan-1-ol
14861-60-0

1-(thiophen-3-yl)ethan-1-ol

Conditions
ConditionsYield
In tetrahydrofuran at 0℃; for 2h;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

N-Phenylhydroxylamine
100-65-2

N-Phenylhydroxylamine

(Z)-N-phenyl-1-(thiophen-3-yl)methanimine oxide

(Z)-N-phenyl-1-(thiophen-3-yl)methanimine oxide

Conditions
ConditionsYield
In ethanol at 21℃; Inert atmosphere;99%
In ethanol Heating; sonication;79%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

nitromethane
75-52-5

nitromethane

(S)-(+)-2-nitro-1-(thiophen-3-yl)ethanol
1040923-87-2

(S)-(+)-2-nitro-1-(thiophen-3-yl)ethanol

Conditions
ConditionsYield
With copper(II) acetate monohydrate; N-ethyl-N,N-diisopropylamine; N-<(1S,2R,4R)-1,7,7-trimethylbicyclo<2.2.1>hept-2-yl>-1-(2-pirydyl)methanamine In ethanol at -50℃; Henry reaction; optical yield given as %ee; enantioselective reaction;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

D,L-histidine
71-00-1

D,L-histidine

C11H11N3O2S
1135901-64-2

C11H11N3O2S

Conditions
ConditionsYield
With potassium carbonate In ethanol at 80℃; for 24h; Molecular sieve;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

5-hydroxy-4,6-dimethyl-3-heptanone
71699-33-7

5-hydroxy-4,6-dimethyl-3-heptanone

thiophene-3-carboxylic acid (1SR,2SR,3SR)-3-hydroxy-1-isopropyl-2-methylpentyl ester

thiophene-3-carboxylic acid (1SR,2SR,3SR)-3-hydroxy-1-isopropyl-2-methylpentyl ester

Conditions
ConditionsYield
With samarium diiodide; benzaldehyde In tetrahydrofuran at -15℃; for 1h; Evans-Tishchenko coupling reaction; Inert atmosphere; optical yield given as %de; diastereoselective reaction;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

2-bromo-5-methoxy-benzaldehyde
7507-86-0

2-bromo-5-methoxy-benzaldehyde

2-bromo-5-methoxybenzyl thiophene-3-carboxylate
1431656-04-0

2-bromo-5-methoxybenzyl thiophene-3-carboxylate

Conditions
ConditionsYield
With 4-tert-butylbenzyl mercaptan; dibutylmagnesium In tetrahydrofuran at 65℃; for 24h; Tishchenko-Claisen Dismutation; Inert atmosphere; chemoselective reaction;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

2-bromoaniline
615-36-1

2-bromoaniline

C11H10BrNS

C11H10BrNS

Conditions
ConditionsYield
In toluene at 130℃; Solvent; Temperature; Inert atmosphere; Molecular sieve;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

1,1,3‐tribromo‐2,2‐dimethylcyclopropane
23534-97-6

1,1,3‐tribromo‐2,2‐dimethylcyclopropane

(3,3-dimethylcycloprop-1-en-1-yl)(thiophen-3-yl)methanol

(3,3-dimethylcycloprop-1-en-1-yl)(thiophen-3-yl)methanol

Conditions
ConditionsYield
Stage #1: 1,1,3‐tribromo‐2,2‐dimethylcyclopropane With n-butyllithium In diethyl ether; hexane at -78 - -10℃; for 1h; Inert atmosphere;
Stage #2: 3-thiophene carboxaldehyde In diethyl ether; hexane at -50 - -10℃; for 0.25h; Inert atmosphere;
99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

tryptamine
61-54-1

tryptamine

1-(thiophen-3-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

1-(thiophen-3-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

Conditions
ConditionsYield
Stage #1: 3-thiophene carboxaldehyde; tryptamine With trifluoroacetic acid In 1,2-dichloro-ethane at 110℃; for 0.0333333h; Pictet-Spengler Synthesis; Sealed tube; Microwave irradiation;
Stage #2: With hydrogenchloride In ethyl acetate at 20℃;
99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

C11H17BO3S

C11H17BO3S

Conditions
ConditionsYield
With FeBr2*2THF; C30H46N4Si2(2+) In acetonitrile at 20℃; for 12h; Glovebox; Inert atmosphere; Sealed tube;99%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

2,2,4,4-tetramethyl-1,3-cyclobutanedione
933-52-8

2,2,4,4-tetramethyl-1,3-cyclobutanedione

6-(3’-thienyl)-3,3,5,5-tetramethyloxane-2,4-dione

6-(3’-thienyl)-3,3,5,5-tetramethyloxane-2,4-dione

Conditions
ConditionsYield
With potassium ethoxide In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;99%

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