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Shandong Xinhua Pharmaceutical Co.,Ltd

Appearance:colorless liquid Package:200kg/drum

Dimethyl malonate

Cas:108-59-8

Min.Order:0

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Dimethyl malonate Manufacturer/High quality/Best price/In stock

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Dimethylmalonate supplier in China

Cas:108-59-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name Dimethyl malonate CAS number 108-59-8 Assay ≥99.5% Appearance Colorless transparent liquid Capacity 1000mt/year Application Pharmaceutical,

Dimethyl malonate

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $12.0

Type:Lab/Research institutions

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Dimethyl malonate Manufacturer/High quality/Best price/In stock CAS NO.108-59-8

Cas:108-59-8

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Dimethylmalonate

Cas:108-59-8

Min.Order:1

Negotiable

Type:Other

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EAST CHEMSOURCES LIMITED

Used in pharmaceutical and organic synthesis Appearance:colorless transparent liquid Storage:Store in a cool, dry, well ventilated warehouse. Package:200kg PE drum or 1000kg IBC tank Application:Used in pharmaceutical and organic synthesis Port:Any

Dimethyl malonate

Cas:108-59-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Propanedioicacid, 1,3-dimethyl ester 108-59-8 ISO Producer

Cas:108-59-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Dimethyl malonate

Cas:108-59-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Dimethyl malonate CAS 108-59-8 Methyl malonate CAS no 108-59-8 Propanedioic acid dimethyl ester Dimethyl malonate CAS 108-59-8 IN Stock CAS 108-59-8 Methyl malonate Dimethyl malonate COA TDS price MSDS Dimethyl malonate MSDS Product no. chemw

Dimethyl malonate CAS 108-59-8 Methyl malonate CAS no 108-59-8 Propanedioic acid dimethyl ester

Cas:108-59-8

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Dimethyl malonate

Cas:108-59-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

Dimethyl malonate CAS:108-59-8

Cas:108-59-8

Min.Order:1 Metric Ton

FOB Price: $2200.0 / 2500.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 108-59-8 with best quality

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 108-59-8 ,Dimethyl malonate

Cas:108-59-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

Dimethyl malonate CAS108-59-8

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name Dimethyl malonate English name Dimethyl malonate Alias Dimethylmalonate; Dimethyl Caroate; Methyl Malonate CAS RN 108-59-8 Molecular weight 132.11612 Molecular formula

Dimethyl malonate CAS:108-59-8

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:clear colorless liquid Storage:Store below +30°C. Package:200kg/Drum Application:It is used in fragrances and some artificial flavorings . Transportation:Express/Sea/Air Port:Any port in China

Dimethyl malonate with high quality

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:liquid Storage:Store in sealed containers at cool & dry plac

Factory Supplier Propanedioicacid, 1,3-dimethyl ester CAS 108-59-8

Cas:108-59-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanedioicacid, 1,3-dimethyl ester 108-59-8

Cas:108-59-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Dimethyl malonate CAS:108-59-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

Dimethyl malonate CAS:108-59-8

Cas:108-59-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propanedioicacid, 1,3-dimethyl ester

Cas:108-59-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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HUBEI RISON CHEMICAL CO.,LTD.

Our Advantages: I). We have abundant professional production experience. II). We have our own chemical factory. III). Sample is free of charge. IV). Reasonable Price, Excellent Quality & Attentive Service V). Prompt reply: we can reply you

HIGH QUALITY Dimethyl malonate methylmalonate

Cas:108-59-8

Min.Order:500 Kilogram

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:108-59-8

Cas:108-59-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Lonwin Chemical Group Limited

Dimethyl malonate CAS:Dimethyl malonate Specification Items Specifications Appearance Colorless liquid Purity ≧99% Acidity ≤0.07%

Factory Supply Dimethylmalonate

Cas:108-59-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

DIMETHYL MALONATE CAS NO.108-59-8

Cas:108-59-8

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Dimethyl Malonate

Cas:108-59-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:Transparent liquid / Refer to COA Storage:Refer

99.5% Dimethyl malonate 108-59-8 cas door to door shipping

Cas:108-59-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Dimethyl malonate

Cas:108-59-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

DIMETHYL MALONATE

Cas:108-59-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

dimethyl malonate

Cas:108-59-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

malonic acid
141-82-2

malonic acid

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With boron trifluoride at 65℃; for 0.333333h;100%
zirconium(IV) oxide; molybdenum at 84.85℃; for 6h; Esterification;95%
iodine for 15h; Heating;94%
malonic acid
141-82-2

malonic acid

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With sulfuric acid at 80 - 85℃; for 2h; Neat (no solvent);99.8%
Malonic acid monomethyl ester
16695-14-0

Malonic acid monomethyl ester

methyl chloroformate
79-22-1

methyl chloroformate

A

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

B

CO2

CO2

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 4℃; for 0.5h;A 95%
B n/a
Malonic acid monomethyl ester
16695-14-0

Malonic acid monomethyl ester

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
95%
Co2 (CO)8

Co2 (CO)8

methyl chloroacetate
96-34-4

methyl chloroacetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With sodium methylate In methanol91%
With sodium hydroxide In methanol87%
N--p-toluolsulfonamid
13750-34-0

N--p-toluolsulfonamid

A

N--p-toluolsulfonamid
84274-88-4

N--p-toluolsulfonamid

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With sodium methylate; malonic acid dimethyl ester In methanol for 8h; Ambient temperature;A 90%
B 84%
methyl chloroacetate
96-34-4

methyl chloroacetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With potassium methanolate In methanol; Co2 (CO)890%
methanol
67-56-1

methanol

dicobalt(η2-(C,C)-ketene)(CO)7

dicobalt(η2-(C,C)-ketene)(CO)7

A

acetic acid methyl ester
79-20-9

acetic acid methyl ester

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With carbon monoxide In methanol Carbonylation at 50 atm.;A 77%
B 7%
2-hydroxyethylhydrazine
109-84-2

2-hydroxyethylhydrazine

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

A

7,7-dimethyl-2,3,7,7a-tetrahydropyrazolo<5,1-b>oxazole

7,7-dimethyl-2,3,7,7a-tetrahydropyrazolo<5,1-b>oxazole

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In methanol for 8h; Heating;A 75%
B 73%
methanol
67-56-1

methanol

dichloromethane
75-09-2

dichloromethane

carbon monoxide
201230-82-2

carbon monoxide

A

Dimethoxymethane
109-87-5

Dimethoxymethane

B

acetic acid methyl ester
79-20-9

acetic acid methyl ester

C

methyl methoxyacetate
6290-49-9

methyl methoxyacetate

D

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With Methyl formate; sodium methylate; Co2(CO)6{P(C4H9-n)3}2 at 80℃; under 11250.9 Torr; for 15h; electrolysis;A 8%
B n/a
C 3%
D 74.5%
With Methyl formate; sodium methylate; Co2(CO)6{P(C4H9-n)3}2 at 80℃; under 11250.9 Torr; for 15h; Product distribution; Mechanism; electrolysis, var. of catalyst, its reduction method, ratio;A 8%
B n/a
C 3%
D 74.5%
With sodium hydroxide; carbon-doped cobalt at 80℃; under 23560 Torr; for 1h;A 1.2 % Chromat.
B 7.5 % Chromat.
C 1.9 % Chromat.
D 28.8 % Chromat.
dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

(3-hydroxypropyl)hydrazine
40440-12-8

(3-hydroxypropyl)hydrazine

A

3,3-dimethyl-3,3a,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazine

3,3-dimethyl-3,3a,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazine

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In methanol for 8h; Heating;A 74%
B 70%
1-hydrazinyl-2-methylpropan-2-ol
42287-37-6

1-hydrazinyl-2-methylpropan-2-ol

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

A

2,2,7,7-tetramethyl-2,3,7,7a-tetrahydropyrazolo<5,1-b>oxazole

2,2,7,7-tetramethyl-2,3,7,7a-tetrahydropyrazolo<5,1-b>oxazole

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In methanol for 8h; Heating;A 71%
B 68%
4-hydroxybutylhydrazine
84157-94-8

4-hydroxybutylhydrazine

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

A

3,3-dimethyl-3,3a,5,6,7,8-hexahydropyrazolo<5,1-b><1,3>oxazepine

3,3-dimethyl-3,3a,5,6,7,8-hexahydropyrazolo<5,1-b><1,3>oxazepine

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In methanol for 8h; Heating;A 69%
B 67%
methanol
67-56-1

methanol

malononitrile
109-77-3

malononitrile

A

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With boron trifluoride diethyl etherate for 68h; Heating;A 68%
B 28%
dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

dimethyl 3-(t-butylimino)-2,2-dimethylpropylidenemalonate

3-hydrazino-2,2-dimethyl-1-propanol

3-hydrazino-2,2-dimethyl-1-propanol

A

3,3,6,6-tetramethyl-3,3a,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazine
90832-25-0

3,3,6,6-tetramethyl-3,3a,6,7-tetrahydro-5H-pyrazolo<5,1-b><1,3>oxazine

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In methanol for 8h; Heating;A 67%
B 63%
methylene chloride
74-87-3

methylene chloride

sodium malonate
141-95-7

sodium malonate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
tetrahexylammonium bromide at 125℃; for 4h;67%
tetrabutylammomium bromide at 125℃; for 5h;64%
tetrabutylammomium bromide at 100℃; for 4h;58%
methanol
67-56-1

methanol

malonodiamide
108-13-4

malonodiamide

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With Amberlyst 15 at 60℃; for 24h;63%
methanol
67-56-1

methanol

cyclohexa-1,4-diene
1165952-92-0

cyclohexa-1,4-diene

A

methyl 3,3-dimethoxypropionate
7424-91-1

methyl 3,3-dimethoxypropionate

B

malonaldehydebis(dimethylacetal)
102-52-3

malonaldehydebis(dimethylacetal)

C

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With hydrogenchloride; ozone -40 deg C, then ca. 30 min reflux; Yields of byproduct given;A 60%
B n/a
C n/a
With hydrogenchloride; ozone at -40℃; -40 deg C, then ca. 30 min reflux; Yield given;A 60%
B n/a
C n/a
With hydrogenchloride; ozone at -40℃; Product distribution;A 60%
B n/a
C n/a
malonic acid
141-82-2

malonic acid

methyl iodide
74-88-4

methyl iodide

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide at 20℃; for 2h;54%
bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

3-(methoxycarbonyl)oxazolidin-2-one

3-(methoxycarbonyl)oxazolidin-2-one

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With zinc In tetrahydrofuran 1) 30 deg C, 2 h, 2) reflux, 18 h;53%
carbon monoxide
201230-82-2

carbon monoxide

sodium methylate
124-41-4

sodium methylate

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

A

methyl methoxyacetate
6290-49-9

methyl methoxyacetate

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
iron pentacarbonyl In tetrahydrofuran at 55℃; under 3800 Torr;A n/a
B 45%
dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

cyclopentanone
120-92-3

cyclopentanone

A

3-(1,1-Bismethoxycarbonylmethyl)cyclopent-1-one
111209-96-2

3-(1,1-Bismethoxycarbonylmethyl)cyclopent-1-one

B

2-(Cyclopent-1-enyloxy)-malonic acid dimethyl ester

2-(Cyclopent-1-enyloxy)-malonic acid dimethyl ester

C

1,3-dimethyl 2-(2-oxocyclopentyl)propanedioate
168566-72-1

1,3-dimethyl 2-(2-oxocyclopentyl)propanedioate

D

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
benzophenone for 10h; Irradiation; Further byproducts given;A 9%
B 15%
C 39%
D 28%
dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

butanone
78-93-3

butanone

A

methyl 2-(methoxycarbonyl)-3-methyl-4-oxopentanonate

methyl 2-(methoxycarbonyl)-3-methyl-4-oxopentanonate

B

2-ethyl-2-methyl-5-(methoxycarbonyl)-1,3-dioxolan-4-one

2-ethyl-2-methyl-5-(methoxycarbonyl)-1,3-dioxolan-4-one

C

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
benzophenone for 14h; Product distribution; Irradiation;A 31%
B 8%
C 26%
for 14h; Irradiation;A 31%
B 8%
C 26%
methanol
67-56-1

methanol

1,3-difluoro-1,1,3,3-tetranitropropane
22692-28-0

1,3-difluoro-1,1,3,3-tetranitropropane

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
at 60℃; for 3h;30%
dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

acetone
67-64-1

acetone

A

dimethyl 2-hydroxymalonate
34259-29-5

dimethyl 2-hydroxymalonate

B

methyl 2-(methoxycarbonyl)-4-oxopentanonate
24889-15-4

methyl 2-(methoxycarbonyl)-4-oxopentanonate

C

methyl 2,2-dimethyl-5-oxo-1,3-dioxolane-4-carboxylate
62609-79-4

methyl 2,2-dimethyl-5-oxo-1,3-dioxolane-4-carboxylate

D

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
benzophenone for 10h; Irradiation;A 25%
B 5%
C 25%
D 2%
dimethyl 2-bromomalonate
868-26-8

dimethyl 2-bromomalonate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); H2B(μ-3,5-dimethylpyrazole)2BH2 In toluene at 85℃; for 1h; Inert atmosphere;25%
With 5-Hexen-1-ol; C30H26N6Ru(2+)*2Cl(1-); triethylamine In N,N-dimethyl-formamide Inert atmosphere; Irradiation;
With 1,2,3,4-tetrakis(carbazol-9-yl)-5,6-dicyanobenzene; triethylamine In 1-methyl-pyrrolidin-2-one at 20℃; for 0.166667h; Inert atmosphere; Irradiation;48 %Chromat.
dimethyl methoxymalonate
5018-30-4

dimethyl methoxymalonate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
In ethanol for 2h; UV-irradiation;21%
dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

acetaldehyde
75-07-0

acetaldehyde

A

dimethyl acetamidomalonate
60187-67-9

dimethyl acetamidomalonate

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
benzophenone for 8h; Irradiation;A 3%
B 15%
dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

1,2,2-trimethyl-bicyclo{1.1.0}butane
28569-96-2

1,2,2-trimethyl-bicyclo{1.1.0}butane

A

1,1-dicarbomethoxy-3,3,4-trimethylpenta-1,4-diene
80530-76-3

1,1-dicarbomethoxy-3,3,4-trimethylpenta-1,4-diene

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
for 10h; Irradiation; Further byproducts given;A 14.2%
B n/a
benzaldehyde
100-52-7

benzaldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-benzylidenepropanedioate
6626-84-2

dimethyl 2-benzylidenepropanedioate

Conditions
ConditionsYield
With rac-Pro-OH In dimethyl sulfoxide at 20℃; for 16h; Knoevenagel condensation;100%
With piperidine; acetic acid In benzene Knoevenagel Condensation; Dean-Stark; Reflux; Inert atmosphere;99%
With amino-tagged Zr based metal organic frame work(UiO-66-NH-RNH2) In toluene at 23℃; for 2h; Knoevenagel Condensation;99%
2-nitro-benzaldehyde
552-89-6

2-nitro-benzaldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-[(2-nitrophenyl)methylidene]malonate
65974-52-9

dimethyl 2-[(2-nitrophenyl)methylidene]malonate

Conditions
ConditionsYield
With piperidine; acetic acid In benzene at 80℃; for 15h; Knoevenagel Condensation; Microwave irradiation;100%
With piperidin-1-ium piperidine-1-carboxylate In neat (no solvent) at 25℃; Knoevenagel Condensation;87%
With potassium carbonate In acetic anhydride at 80℃; for 4h;86%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-(hydroxyimino)malonate
42937-74-6

dimethyl 2-(hydroxyimino)malonate

Conditions
ConditionsYield
With acetic acid; sodium nitrite In water at 0 - 20℃;100%
With acetic acid; sodium hydroxide; sodium nitrite In water at 5 - 20℃; for 24h;95%
With hydrogenchloride; 1-(4-(nitrosooxy)butyl)-3-methylimidazolium chloride; water at 20℃;94%
acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

trimethyl 4-oxocyclohexane-1,1,3-tricarboxylate
80269-67-6

trimethyl 4-oxocyclohexane-1,1,3-tricarboxylate

Conditions
ConditionsYield
With sodium hydride100%
With sodium methylate In methanol for 1h; Heating;
With sodium In methanol; water
isovaleraldehyde
590-86-3

isovaleraldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-(3-methylbutylidene)malonate
53618-21-6

dimethyl 2-(3-methylbutylidene)malonate

Conditions
ConditionsYield
With chromatorex NH In toluene at 70℃; Reagent/catalyst; Temperature; Knoevenagel Condensation; Flow reactor; Molecular sieve;100%
With L-proline In dimethyl sulfoxide at 20℃; Reagent/catalyst; Knoevenagel Condensation;97%
With rac-Pro-OH In dimethyl sulfoxide at 20℃; for 16h; Knoevenagel condensation;92%
cyclohexenone
930-68-7

cyclohexenone

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-(3-oxocyclohexyl)malonate
33646-18-3

dimethyl 2-(3-oxocyclohexyl)malonate

Conditions
ConditionsYield
(anthracenebisresorcinol(4-):2La(3+))polymer In benzene at 20℃; for 48h; Michael addition;100%
at 20℃; for 12h; Michael addition; Electrolysis;98%
Stage #1: malonic acid dimethyl ester at 20℃; Electrolysis;
Stage #2: cyclohexenone at 20℃; for 12h; Michael addition;
98%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl diazomalonate
6773-29-1

dimethyl diazomalonate

Conditions
ConditionsYield
With 4-acetamidobenzenesulfonyl azide; triethylamine In acetonitrile Inert atmosphere;100%
With 4-acetamidobenzenesulfonyl azide; triethylamine In acetonitrile at 20℃; for 24h; Inert atmosphere;99%
With 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 0 - 20℃; for 1h;99%
benzyl bromide
100-39-0

benzyl bromide

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

2-benzyl-malonic acid dimethyl ester
49769-78-0

2-benzyl-malonic acid dimethyl ester

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide; toluene at 18℃; for 3h;100%
With sodium hydride In tetrahydrofuran at 20℃; for 2h;82%
Stage #1: malonic acid dimethyl ester With sodium hydride In tetrahydrofuran; paraffin oil at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: benzyl bromide In tetrahydrofuran; paraffin oil at 20℃; for 2h; Inert atmosphere;
78%
1-(p-toluenesulfonyl)-1H-imidazole-4(5)-carboxaldehyde
37622-92-7

1-(p-toluenesulfonyl)-1H-imidazole-4(5)-carboxaldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 1(p-toluenesulfonyl)-1H-imidazol-4(5)-ylmethylenemalonate
139285-01-1

dimethyl 1(p-toluenesulfonyl)-1H-imidazol-4(5)-ylmethylenemalonate

Conditions
ConditionsYield
With piperidine; acetic acid In benzene at 40℃; for 3h;100%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-(cyclohex-2-en-1-yl)malonate
34939-28-1

dimethyl 2-(cyclohex-2-en-1-yl)malonate

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); N,O-bis-(trimethylsilyl)-acetamide; N,N'-bis(diphenylphosphino)-N,N'-dimethylethane-1,2-diamine In tetrahydrofuran at 20℃; for 0.85h; Product distribution; var. ligand: dppb, var. chiral ligands (R,R)-DIOP, S,S-BPPM, etc.):ee = 5-40percent;100%
With bis(1,5-cyclooctadiene)nickel (0); N,O-bis-(trimethylsilyl)-acetamide; N,N'-bis(diphenylphosphino)-N,N'-dimethylethane-1,2-diamine In tetrahydrofuran at 20℃; for 0.85h;100%
Stage #1: malonic acid dimethyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.25h; Metallation;
Stage #2: rac-3-acetoxycyclohexene With tetrakis(triphenylphosphine) palladium(0); triphenylphosphine In tetrahydrofuran for 4h; Alkylation; deacetoxylation; Heating;
92%
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

(E)-dimethyl (1,3-diphenylprop-2-en-1-yl)propanedioate
177468-91-6

(E)-dimethyl (1,3-diphenylprop-2-en-1-yl)propanedioate

Conditions
ConditionsYield
With benzenesulfonamide; potassium acetate; [(η3-C3H5)Pd(SC6F4H-4)(P(C6H4OMe-4)3)] In dichloromethane at 20℃; for 4h;100%
With caesium carbonate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; bis(2,6-diisopropylphenyl)imidazolium salt In tetrahydrofuran at 50℃; for 10h; Tsuji-Trost reaction;100%
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride In tetrahydrofuran at 50℃; for 10h;100%
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2-[(E)-(S)-1,3-diphenylallyl]-malonate
95071-02-6, 96482-67-6, 131065-36-6, 148553-10-0, 96482-64-3

dimethyl 2-[(E)-(S)-1,3-diphenylallyl]-malonate

Conditions
ConditionsYield
Stage #1: malonic acid dimethyl ester With 15-crown-5; sodium hydride In acetonitrile at 20℃; for 0.5h; Metallation;
Stage #2: rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene; chiral 2-(phosphinoaryl)pyridine palladium In acetonitrile at 0℃; for 1h; Alkylation;
100%
With chiral 1-dinaphthoazepino-2-dinaphthophosphepinoethane*BH3; potassium acetate; bis-(trimethylsilyl)acetamide; palladium diacetate In dichloromethane at 20℃; for 6h;100%
With bis(η3-allyl-μ-chloropalladium(II)); C28H36N4O4P2; tetrabutylammomium bromide; potassium carbonate In dichloromethane at 20℃; for 18h; Tsuji-Trost reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;100%
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
87751-69-7

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

(R)-methyl 2-carbomethoxy-3,5-diphenylpent-4-enoate
95071-02-6, 96482-64-3, 131065-36-6, 148553-10-0, 96482-67-6

(R)-methyl 2-carbomethoxy-3,5-diphenylpent-4-enoate

Conditions
ConditionsYield
With 1,2-bis[(R)-dinaphthoazepino]ethane ligand; potassium acetate; bis-(trimethylsilyl)acetamide; [(ν3-allyl)PdCl]2 In dichloromethane at 20℃; for 2h;100%
With bis(η3-allyl-μ-chloropalladium(II)); C2-symmetric chiral P; potassium acetate; bis-(trimethylsilyl)acetamide In dichloromethane for 0.5h; Ambient temperature;99%
With benzenesulfonamide; (C6H13)4N(+); bis(η3-allyl-μ-chloropalladium(II)); (R,S)-phosphinooxazoline In acetonitrile99%
methyl (E)-2-carbomethoxy-2-<(E)-4-chloro-2-butenyl>-8-<(tetrahydro-2H-pyran-2-yl)oxy>-6-octenoate
111014-37-0

methyl (E)-2-carbomethoxy-2-<(E)-4-chloro-2-butenyl>-8-<(tetrahydro-2H-pyran-2-yl)oxy>-6-octenoate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

methyl (E),(E)-2,7,7-tricarbomethoxy-13-<(tetrahydro-2H-pyran-2-yl)oxy>-4,11-tridecadienoate
111014-38-1

methyl (E),(E)-2,7,7-tricarbomethoxy-13-<(tetrahydro-2H-pyran-2-yl)oxy>-4,11-tridecadienoate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide for 1.5h; Heating;100%
methyl 2-carbomethoxy-2-<(Z)-4-chloro-2-butenyl>-8-<(tetrahydro-2H-pyran-2-yl)oxy>-6-octynoate
111014-39-2

methyl 2-carbomethoxy-2-<(Z)-4-chloro-2-butenyl>-8-<(tetrahydro-2H-pyran-2-yl)oxy>-6-octynoate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

methyl (Z)-2,7,7-tricarbomethoxy-13-<(tetrahydro-2H-pyran-2-yl)oxy>-4-tridecen-11-ynoate
111014-40-5

methyl (Z)-2,7,7-tricarbomethoxy-13-<(tetrahydro-2H-pyran-2-yl)oxy>-4-tridecen-11-ynoate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide for 1.5h; Heating;100%
2-((Z)-4-Chloro-but-2-enyl)-2-[8-(tetrahydro-pyran-2-yloxy)-oct-6-ynyl]-malonic acid dimethyl ester
114939-22-9

2-((Z)-4-Chloro-but-2-enyl)-2-[8-(tetrahydro-pyran-2-yloxy)-oct-6-ynyl]-malonic acid dimethyl ester

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

(Z)-2,7-Bis-methoxycarbonyl-2-[8-(tetrahydro-pyran-2-yloxy)-oct-6-ynyl]-oct-4-enedioic acid dimethyl ester
114939-30-9

(Z)-2,7-Bis-methoxycarbonyl-2-[8-(tetrahydro-pyran-2-yloxy)-oct-6-ynyl]-oct-4-enedioic acid dimethyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide for 1.5h; Heating;100%
12-Benzyl-6,7,12,12b-tetrahydro-1H-indolo[2,3-a]quinolizine-4-thione
145471-52-9

12-Benzyl-6,7,12,12b-tetrahydro-1H-indolo[2,3-a]quinolizine-4-thione

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

2-((2R,12bS)-12-Benzyl-4-thioxo-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-malonic acid dimethyl ester
145471-53-0

2-((2R,12bS)-12-Benzyl-4-thioxo-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-malonic acid dimethyl ester

Conditions
ConditionsYield
With caesium carbonate In tetrahydrofuran at 20℃; for 5h;100%
2,2,2-Trichloro-acetimidic acid 2-cyclopropylidene-ethyl ester
169308-84-3

2,2,2-Trichloro-acetimidic acid 2-cyclopropylidene-ethyl ester

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl (2-cyclopropylideneethyl)malonate
130715-11-6

dimethyl (2-cyclopropylideneethyl)malonate

Conditions
ConditionsYield
With sodium hydride; bis(dibenzylideneacetone)-palladium(0); bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 18h; Ambient temperature;100%
3-acetoxycyclopent-1-ene
20657-21-0

3-acetoxycyclopent-1-ene

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

dimethyl (S)-cyclopent-2-enylmalonate
155057-81-1

dimethyl (S)-cyclopent-2-enylmalonate

B

dimethyl (1R)-(cyclopent-2-en-1-yl)malonate

dimethyl (1R)-(cyclopent-2-en-1-yl)malonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; potassium acetate; bis(η3-allyl-μ-chloropalladium(II)); (Sp)-1-[(1R)-(1-(5-chloro-3H-isobenzofuran-1-ylideneamino)-ethyl)]-2-(diphenylphosphino)-ferrocene In dichloromethane at 20℃; for 16h;A n/a
B 100%
With n-butyllithium; (1S,2R,3S,5R)-3-diphenylphosphinopinan-10-oic acid Pd In tetrahydrofuran at 25℃; for 12h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sodium hydride; bis(η3-allyl-μ-chloropalladium(II)) In tetrahydrofuran at 20℃; for 0.166667h; Product distribution; other solvent, time and temperature;
methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

dimethyl 1,1-cyclopropanedicarboxylate
6914-71-2

dimethyl 1,1-cyclopropanedicarboxylate

B

1-acetylcyclopropanecarboxylic acid methyl ester
38806-09-6

1-acetylcyclopropanecarboxylic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; 18-crown-6 ether In butanone for 3h; Heating;A 100%
B 75%
propargyl bromide
106-96-7

propargyl bromide

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2,2-di(prop-2-ynyl)malonate
63104-44-9

dimethyl 2,2-di(prop-2-ynyl)malonate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; toluene Alkylation;100%
Stage #1: malonic acid dimethyl ester With sodium hydride In dimethyl sulfoxide; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: propargyl bromide In tetrahydrofuran; mineral oil at 0 - 20℃; for 1.5h;
100%
With sodium hydride In tetrahydrofuran Heating;98%
methallyl acetate
820-71-3

methallyl acetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2,2-di(2-methylallyl)malonate
74793-47-8

dimethyl 2,2-di(2-methylallyl)malonate

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); N,O-bis-(trimethylsilyl)-acetamide; 1,3-bis-(diphenylphosphino)propane In tetrahydrofuran at 20℃; for 2h;100%
acrylonitrile
107-13-1

acrylonitrile

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2,2-bis(2-cyanoethyl)malonate

dimethyl 2,2-bis(2-cyanoethyl)malonate

Conditions
ConditionsYield
With 1-butyl-4-aza-1-azoniabicyclo[2.2.2]octane hydroxide at 20℃; for 0.0166667h; Reagent/catalyst; Time; Michael Addition; Green chemistry;100%
With tetrabutylammomium bromide; potassium carbonate In hexane Michael condensation; Reflux;92%
With 1-butyl-3-methylimidazolium hydroxide at 20℃; for 3h; Michael addition;82%
2-cycloheptenyl acetate
826-13-1

2-cycloheptenyl acetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

dimethyl (R)-cyclohept-2-enylmalonate

dimethyl (R)-cyclohept-2-enylmalonate

B

dimethyl (S)-cyclohept-2-enylmalonate

dimethyl (S)-cyclohept-2-enylmalonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; sodium acetate; bis(η3-allyl-μ-chloropalladium(II)); (Sp)-1-[(1R)-(1-(5-chloro-3H-isobenzofuran-1-ylideneamino)-ethyl)]-2-(diphenylphosphino)-ferrocene In dichloromethane at 20℃; for 16h;A 100%
B n/a
With benzenesulfonamide; N-(2-diphenylphosphino)benzyl-3,5-dihydro-4H-dinaphth<2,1-c:1',2'-e>azepine; In dichloromethane for 18h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With sodium hydride; bis(η3-allyl-μ-chloropalladium(II)) In tetrahydrofuran at 20℃; for 0.0833333h; Product distribution; other solvent, time and temperature; various chiral ligands;
2-cycloheptenyl acetate
826-13-1

2-cycloheptenyl acetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl (R)-cyclohept-2-enylmalonate

dimethyl (R)-cyclohept-2-enylmalonate

Conditions
ConditionsYield
Stage #1: 2-cycloheptenyl acetate With bis(η3-allyl-μ-chloropalladium(II)); (Sp)-1-[(1R)-(1-(5-chloro-3H-isobenzofuran-1-ylideneamino)-ethyl)]-2-(diphenylphosphanyl)ferrocene In dichloromethane at 20℃; for 0.5h; Inert atmosphere;
Stage #2: malonic acid dimethyl ester With N,O-bis-(trimethylsilyl)-acetamide; sodium acetate In dichloromethane at 20℃; for 16h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;
100%
With sodium hydride; bis(η3-allyl-μ-chloropalladium(II)); <1-((4S)-4-tert-butyl-4,5-dihydroo; xazol-2-yl)-2-<(biphenyl-2-yl)phenylphosphanyl>cyclopentadienyl>Mn(CO)3 In N,N-dimethyl-formamide at 0℃; for 1.25h;86%
With N,O-bis-(trimethylsilyl)-acetamide; bis(η3-allyl-μ-chloropalladium(II)); C40H47O5PSSi2; potassium acetate In dichloromethane at 23℃; for 6h; Inert atmosphere; Schlenk technique; enantioselective reaction;86%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

(2R,4S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine
203207-92-5

(2R,4S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine

2-[(2R,4S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-4-yl]-malonic acid dimethyl ester

2-[(2R,4S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-4-yl]-malonic acid dimethyl ester

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; tin(IV) chloride In dichloromethane at -78 - -20℃;100%
malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

(2S,4S)-2-Methyl-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine

(2S,4S)-2-Methyl-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine

2-[(S)-2-Methyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-4-yl]-malonic acid dimethyl ester

2-[(S)-2-Methyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-4-yl]-malonic acid dimethyl ester

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; tin(IV) chloride In dichloromethane at -78 - -20℃;100%
propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

N,N'-bis(3-hydroxypropyl)propanediamide
53828-48-1

N,N'-bis(3-hydroxypropyl)propanediamide

Conditions
ConditionsYield
at 160℃; for 1h;100%
Benzylidenemalononitrile
2700-22-3

Benzylidenemalononitrile

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 3,3-dicyano-2-phenylpropane-1,1-dicarboxylate

dimethyl 3,3-dicyano-2-phenylpropane-1,1-dicarboxylate

Conditions
ConditionsYield
With triethylamine In diethyl ether Michael addition;100%
With sodium methylate In methanol for 1h;63%
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