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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Methyl cyanoacetate suppliers in China

Cas:105-34-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methylcyanoacetate supplier in China

Cas:105-34-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name Methyl cyanoacetate CAS number 105-34-0 Assay ≥99.5% Appearance Colorless transparent liquid Capacity 500mt/year Application Pharmaceutical/

Methyl cyanoacetate

Cas:105-34-0

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

Methyl cyanoacetate CAS No.: 105-34-0 Appearance: Clear and colorless liquid High quality and competitive price Methyl cyanoacetate a Intermediate of Pharmaceutical and dyestuff , Methyl cyanoacetate is used as an adhesive. Our COA i

Good quality Methyl cyanoacetate//105-34-0 manufacturer

Cas:105-34-0

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methylcyanoacetate

Cas:105-34-0

Min.Order:1

Negotiable

Type:Other

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EAST CHEMSOURCES LIMITED

This product is an intermediate for organic synthesis, medicine and dyes. Mainly used to make adhesives. Appearance:colorless transparent liquid Storage:Store in a cool, dry, well ventilated warehouse. Package:200kg PE drum or 1000kg IBC tank Appli

Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Methyl Cyanoacetate 105-34-0 Producer

Cas:105-34-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cyanoacetic acid methyl ester

Cas:105-34-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

Methyl cyanoacetate CAS:105-34-0

Cas:105-34-0

Min.Order:1 Metric Ton

FOB Price: $2200.0 / 2500.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 105-34-0 with best price

Cas:105-34-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name: Methyl Cyanoacetate Molecular formula: C4H5NO2 Molecular weight: 99.09 Use: Used as matermediate for medicines. Physical and

Methyl Cyanoacetate

Cas:105-34-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:clear colorless to very slighlty yellow liquid Storage:Room temperature Package:25kg/Barrel, 200kg/Barrel Application:Pharmaceutical and dye intermediates Transportation:Express/Sea/Air Port:Any port in china

Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methyl cyanoacetate 105-34-0

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:Colorless to slightly yellow transparent liquid

Methyl cyanoacetate 105-34-0 cas 99.6% ready stock

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Methyl cyanoacetate CAS:105-34-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

Methyl cyanoacetate CAS:105-34-0

Cas:105-34-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HUBEI RISON CHEMICAL CO.,LTD.

Our Advantages: I). We have abundant professional production experience. II). We have our own chemical factory. III). Sample is free of charge. IV). Reasonable Price, Excellent Quality & Attentive Service V). Prompt reply: we can reply you

HIGH QUALITY Methyl cyanoacetate

Cas:105-34-0

Min.Order:500 Kilogram

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Methyl cyanoacetate

Cas:105-34-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Methyl Cyanoacetate CAS NO.105-34-0

Cas:105-34-0

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Methyl Cyanoacetate

Cas:105-34-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl cyanoacetate fast delivery /105-34-0 in stock /good supplier

Cas:105-34-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory supply Methyl Cyanoacetate

Cas:105-34-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl cyanoacetate

Cas:105-34-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Methyl cyanoacetate CAS 105-34-0 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality contro

Methyl cyanoacetate CAS 105-34-0

Cas:105-34-0

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL CYANOACETATE

Cas:105-34-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Methyl cyanoacetate

Cas:105-34-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 25.0

Type:Lab/Research institutions

inquiry

Hebei Miheng Trading Co., Ltd.

Methyl cyanoacetate CAS 105-34-0 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assemb

Methyl cyanoacetate CAS 105-34-0

Cas:105-34-0

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

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Synthetic route

methanol
67-56-1

methanol

cyanoacetic acid
372-09-8

cyanoacetic acid

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane for 1h; Ambient temperature;97%
With N-Bromosuccinimide at 70℃; for 20h;97%
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione at 70℃; for 20h;97%
3-Methoxypropionitrile
110-67-8

3-Methoxypropionitrile

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; cobalt(II) acetate In acetic acid at 130 - 190℃; under 6750.68 Torr; for 3 - 7h;
methyl N-formylglycinate
3154-54-9

methyl N-formylglycinate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With triethylamine; trichlorophosphate In dichloromethane at 0℃; for 1h;
methanol
67-56-1

methanol

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
scandium tris(trifluoromethanesulfonate) at 64℃; for 8h;89%
With titanium(IV) isopropylate for 2h; Inert atmosphere; Reflux;80%
With potassium fluoride
acrylonitrile; triphenylphosphine at 25℃; for 1h;100 % Chromat.
With HZnPS-1, porous sulfonated zinc phosphonate material at 24.84℃; for 24h;520 mg
methyl chloroacetate
96-34-4

methyl chloroacetate

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
at 70℃; for 2.5h; Temperature;96.2%
methylene chloride
74-87-3

methylene chloride

cyanoacetic acid
372-09-8

cyanoacetic acid

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium hydroxide; tetrabutylammomium bromide In tert-butyl methyl ether; water
methanol
67-56-1

methanol

cyanoacetic acid amide
107-91-5

cyanoacetic acid amide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With Amberlyst 15 at 60℃; for 18h;85%
dimethyl 2,3-dicyanofumarate
35234-87-8

dimethyl 2,3-dicyanofumarate

malononitrile
109-77-3

malononitrile

A

methyl tricyanoethylenecarboxylate
101342-43-2

methyl tricyanoethylenecarboxylate

B

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
In acetic acid at 100℃; for 0.5h;A 30%
B n/a
sodium cyanide
143-33-9

sodium cyanide

methyl chloroacetate
96-34-4

methyl chloroacetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With PEG400 at 120℃; for 5h;84%
With water; acetic acid at 80 - 85℃;
methyl malonamate
51513-29-2

methyl malonamate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With lead acetate In dichloromethane for 12h; Reflux;86%
sodium methylate
124-41-4

sodium methylate

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
at 0℃; for 0.166667h;
methanol
67-56-1

methanol

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

A

ethanol
64-17-5

ethanol

B

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
Stage #1: methanol; ethyl 2-cyanoacetate at 59.84℃; for 0.25h;
Stage #2: With hybrid supermicroporous iron(III) phosphonate nanoparticle (HFeP-1-3) at 59.84℃; for 6h; Reagent/catalyst;
A n/a
B 85.6%
methanol
67-56-1

methanol

2-methoxyethyl cyanoacetate
10258-54-5

2-methoxyethyl cyanoacetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
(EtO)3TiO(CH2)2OTi(OEt)3 for 21h; Heating;88%
potassium cyanide
151-50-8

potassium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

A

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

B

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With methanol
isocyanoacetic acid methyl ester
39687-95-1

isocyanoacetic acid methyl ester

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
at 520 - 550℃; under 0.01 Torr;97%
With 1,1-Diphenylethylene In 1,3,5-trimethyl-benzene at 210℃; Rate constant; Thermodynamic data; ΔG(excit.) <250 deg C>; ΔH(excit.), ΔS(excit.);101 % Chromat.
methanol
67-56-1

methanol

malononitrile
109-77-3

malononitrile

A

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
With boron trifluoride diethyl etherate for 68h; Heating;A 68%
B 28%
methanol
67-56-1

methanol

malononitrile
109-77-3

malononitrile

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With iron(III) chloride for 1h; Heating;71%
methanol
67-56-1

methanol

sodium cyanoacetate
1071-36-9

sodium cyanoacetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With sulfuric acid; benzene
2-cyano-3-methyl-non-2-enoic acid methyl ester

2-cyano-3-methyl-non-2-enoic acid methyl ester

water
7732-18-5

water

piperdinium acetate
4540-33-4

piperdinium acetate

A

2-methylheptanal
16630-91-4

2-methylheptanal

B

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
at 125℃;
chloroform
67-66-3

chloroform

1-cyano-2,2-bis(methoxy)ethylene
15732-02-2

1-cyano-2,2-bis(methoxy)ethylene

bromine (0.6 mol)

bromine (0.6 mol)

A

methyl 2-bromo-2-cyanoacetate
31253-11-9

methyl 2-bromo-2-cyanoacetate

B

2-bromo-3,3-dimethoxy-acrylonitrile
857576-02-4

2-bromo-3,3-dimethoxy-acrylonitrile

C

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
at -10℃;
hydrogenchloride
7647-01-0

hydrogenchloride

methanol
67-56-1

methanol

2-cyano-1,1,1-trimethoxyethane
70138-31-7

2-cyano-1,1,1-trimethoxyethane

A

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

B

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

Conditions
ConditionsYield
at 0℃;
2,4-dicyano-3-hydroxy-3-phenyl-glutaric acid dimethyl ester

2,4-dicyano-3-hydroxy-3-phenyl-glutaric acid dimethyl ester

alcoholic KOH-solution

alcoholic KOH-solution

A

Methyl 2-Cyano-3-oxo-3-phenylpropanoate
3239-71-2

Methyl 2-Cyano-3-oxo-3-phenylpropanoate

B

benzoic acid
65-85-0

benzoic acid

C

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl 2-(4-hydroxybenzylidene)-2-cyanoacetate
3695-85-0

methyl 2-(4-hydroxybenzylidene)-2-cyanoacetate

Conditions
ConditionsYield
at 170℃; for 1h; Knoevenagel condensation;100%
With potassium carbonate; thiourea In water at 20℃; for 0.166667h;98%
With C8H18NO3(1+)*C2H4NO2(1-) In water at 20℃; Knoevenagel Condensation;96%
4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)-2-cyano-3-(4-(N,N-dimethylamino)phenyl)-2-propenoate
3785-86-2, 13432-69-4

methyl (E)-2-cyano-3-(4-(N,N-dimethylamino)phenyl)-2-propenoate

Conditions
ConditionsYield
at 170℃; for 1h; Knoevenagel condensation;100%
With silica sodium carbonate nanoparticles In acetonitrile at 70℃; Knoevenagel Condensation; Sonication; Green chemistry;95%
With tetra(n-butyl)ammonium hydroxide In ethanol; water at 20℃; for 0.166667h; Knoevenagel condensation;94%
4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)-2-cyano-3-(4-chlorophenyl)-2-propenoate
49678-54-8

methyl (E)-2-cyano-3-(4-chlorophenyl)-2-propenoate

Conditions
ConditionsYield
With aluminum oxide Inert atmosphere; Neat (no solvent);100%
With piperidine; acetic acid In benzene for 2.5h; Knoevenagel Condensation; Dean-Stark; Reflux;95%
With copolymer of allylamine and epichlorohydrin (11 molpercent) In water at 20℃; for 0.833333h; Knoevenagel Condensation; Green chemistry;91%
4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)-2-cyano-3-(4-nitrophenyl)-2-propenoate
42348-04-9

methyl (E)-2-cyano-3-(4-nitrophenyl)-2-propenoate

Conditions
ConditionsYield
With calcite grains for 0.5h; Product distribution; Further Variations:; Reagents; Knoevenagel condensation; ball-milling conditions;100%
With aluminum oxide Inert atmosphere; Neat (no solvent);100%
With copolymer of allylamine and epichlorohydrin (11 molpercent) In water at 20℃; for 0.666667h; Knoevenagel Condensation; Green chemistry;93%
benzaldehyde
100-52-7

benzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)-2-cyano-3-phenylprop-2-enoate
14533-86-9

methyl (E)-2-cyano-3-phenylprop-2-enoate

Conditions
ConditionsYield
aluminum oxide for 0.05h; Product distribution; Ambient temperature; investigation of reaction of aldehydes and ketones with active methylene compounds with and without solvent;100%
aluminum oxide for 0.05h; Ambient temperature;100%
With aluminum oxide for 0.0833333h; Inert atmosphere;100%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)- 2-cyano-3-(4-methoxyphenyl)prop-2-enoate
14479-58-4

methyl (E)- 2-cyano-3-(4-methoxyphenyl)prop-2-enoate

Conditions
ConditionsYield
With aluminum oxide Inert atmosphere; Neat (no solvent);100%
With C8H18NO3(1+)*C2H4NO2(1-) In water at 20℃; Knoevenagel Condensation;98%
With piperidine; acetic acid In benzene for 2.5h; Knoevenagel Condensation; Dean-Stark; Reflux;97%
orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

α-ethoxymethylene methyl cyanoacetate
29096-99-9

α-ethoxymethylene methyl cyanoacetate

Conditions
ConditionsYield
Stage #1: orthoformic acid triethyl ester; methyl 2-cyanoacetate at 20 - 30℃;
Stage #2: With acetic anhydride; acetic acid at 30 - 110℃; for 4h; Inert atmosphere;
100%
With acetic anhydride for 3.4h; Time; Reflux;86%
With acetic anhydride
3-phenyl-propenal
104-55-2

3-phenyl-propenal

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-cyano-5-phenyl-2,4-pentadien carboxylic acid methyl ester
85620-43-5

2-cyano-5-phenyl-2,4-pentadien carboxylic acid methyl ester

Conditions
ConditionsYield
aluminum oxide for 0.05h; Ambient temperature;100%
With diammonium phosphate In water at 20℃; Knoevenagel condensation;90%
With Porcine Pancreas Lipase In water; tert-butyl alcohol at 40℃; for 120h; Knoevenagel Condensation; Enzymatic reaction; stereoselective reaction;89%
With aluminum oxide; ammonium acetate for 0.0333333h; Knoevenagel condensation; microwave irradiation (850 watt);70%
4-cyanobenzaldehyde
105-07-7

4-cyanobenzaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

(E)-methyl 2-cyano-3-(4-cyanophenyl)acrylate
102070-03-1

(E)-methyl 2-cyano-3-(4-cyanophenyl)acrylate

Conditions
ConditionsYield
With calcite grains for 0.5h; Product distribution; Further Variations:; Reagents; Knoevenagel condensation; ball-milling conditions;100%
With aluminum oxide Inert atmosphere; Neat (no solvent);100%
xonotlite; potassium tert-butylate for 1h;88%
With piperidine; acetic acid In benzene for 2.5h; Knoevenagel Condensation; Dean-Stark; Reflux;87%
With piperidine; acetic acid In methanol at 20℃; Schlenk technique; Inert atmosphere;82%
trans-5-methyl-2-cyclohexen-1-yl acetate
61221-48-5

trans-5-methyl-2-cyclohexen-1-yl acetate

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Cyano-((1S,5R)-5-methyl-cyclohex-2-enyl)-acetic acid methyl ester

Cyano-((1S,5R)-5-methyl-cyclohex-2-enyl)-acetic acid methyl ester

Conditions
ConditionsYield
With isopropylmagnesium chloride; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride In tetrahydrofuran for 24h; Product distribution; Heating; other catalyst;100%
methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

dimethyl 1,1-cyclopropanedicarboxylate
6914-71-2

dimethyl 1,1-cyclopropanedicarboxylate

B

1-acetylcyclopropanecarboxylic acid methyl ester
38806-09-6

1-acetylcyclopropanecarboxylic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; 18-crown-6 ether In butanone for 3h; Heating;A 100%
B 75%
2-imidazolecarbaldehyde
10111-08-7

2-imidazolecarbaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

(E)-2-Cyano-3-(1H-imidazol-2-yl)-acrylic acid methyl ester

(E)-2-Cyano-3-(1H-imidazol-2-yl)-acrylic acid methyl ester

Conditions
ConditionsYield
With piperidine; acetic acid In toluene for 1h; Ambient temperature;100%
hexanal
66-25-1

hexanal

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

(E)-2-cyano-oct-2-enoic acid methyl ester
111735-80-9

(E)-2-cyano-oct-2-enoic acid methyl ester

Conditions
ConditionsYield
With piperidine; acetic acid at 20℃; for 14h;100%
phenylacetaldehyde
122-78-1

phenylacetaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-amino-5-phenylthiophene-3-carboxylic acid methyl ester
61325-02-8

2-amino-5-phenylthiophene-3-carboxylic acid methyl ester

Conditions
ConditionsYield
With sulfur; N-ethyl-N,N-diisopropylamine In DMF (N,N-dimethyl-formamide) at 18 - 25℃;100%
With sulfur; triethylamine In N,N-dimethyl-formamide at 20℃; for 21h;90%
With sulfur; triethylamine In ethanol at 20℃; for 1h; Gewald reaction; Reflux;63%
1-naphthaldehyde
66-77-3

1-naphthaldehyde

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (E)-2-cyano-3-(naphthen-1-yl)acrylate

methyl (E)-2-cyano-3-(naphthen-1-yl)acrylate

Conditions
ConditionsYield
ytterbium(III) triflate In ethanol at 20℃; for 5h;100%
With piperidine; acetic acid In benzene for 2.5h; Knoevenagel Condensation; Dean-Stark; Reflux;93%
piperidine In methanol at 50 - 60℃; for 0.5 - 10h; Product distribution / selectivity;92.5%
In methanol at 20℃; for 24h; Product distribution / selectivity;
With C112H128N32Pd4(12+) at 50℃; for 9h;
trifluoromethane sulfonyl chloride
421-83-0

trifluoromethane sulfonyl chloride

triethylamine
121-44-8

triethylamine

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl dichlorocyanoacetate
25761-68-6

methyl dichlorocyanoacetate

Conditions
ConditionsYield
In dichloromethane 1:1 molar mixture of educts per acidic hydrogen, 20-25°C, 1 h;100%
In dichloromethane 1:1 molar mixture of educts per acidic hydrogen, 20-25°C, 1 h;100%
trifluoromethane sulfonyl chloride
421-83-0

trifluoromethane sulfonyl chloride

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl dichlorocyanoacetate
25761-68-6

methyl dichlorocyanoacetate

Conditions
ConditionsYield
With 1,5-Diazabicyclo[5.4.0]undec-5-ene In dichloromethane 1:1 molar mixture of educts per acidic hydrogen, 20-25°C, 1 h;100%
With 1,5-diazabicyclo(5.4.0)undec-5-ene In dichloromethane 1:1 molar mixture of educts per acidic hydrogen, 20-25°C, 1 h;100%
trans-[PtOH(Ph)(P-t-BuMe2)2]
76124-95-3

trans-[PtOH(Ph)(P-t-BuMe2)2]

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

trans-Pt(NCCHCO2Me)Ph(P-t-BuMe2)2
76316-38-6

trans-Pt(NCCHCO2Me)Ph(P-t-BuMe2)2

Conditions
ConditionsYield
In benzene stirring at room temp. for 2 h; evapn.; elem. anal.;100%
3,5-di-tert-butylbenzyl bromide
62938-08-3

3,5-di-tert-butylbenzyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

cyano-di(3,5-ditert-butyl-benzyl)acetic acid methyl ester
1202779-03-0

cyano-di(3,5-ditert-butyl-benzyl)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 3,5-di-tert-butylbenzyl bromide In methanol Reflux;
100%
1-Bromo-3-phenylpropane
637-59-2

1-Bromo-3-phenylpropane

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester
1202778-95-7

cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 1-Bromo-3-phenylpropane In methanol Reflux;
100%
3,5-dimethoxybenzyl bromide
877-88-3

3,5-dimethoxybenzyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

cyano-di(3,5-dimethoxy-benzyl)acetic acid methyl ester
1202779-02-9

cyano-di(3,5-dimethoxy-benzyl)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 3,5-dimethoxybenzyl bromide In methanol Reflux;
100%
4-i-propylbenzyl bromide
73789-86-3

4-i-propylbenzyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

cyano-di(4-isopropyl-benzyl)acetic acid methyl ester
1202778-99-1

cyano-di(4-isopropyl-benzyl)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 4-i-propylbenzyl bromide In methanol Reflux;
100%
4-Methylbenzyl bromide
104-81-4

4-Methylbenzyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

cyano-di(4-methyl-benzyl)acetic acid methyl ester
1202778-97-9

cyano-di(4-methyl-benzyl)acetic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 4-Methylbenzyl bromide In methanol Reflux;
100%
2-bromomethylnaphthyl bromide
939-26-4

2-bromomethylnaphthyl bromide

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl 2-cyano-3-(2-naphthyl)-2-[(2-naphthyl)methyl]propionate
1202778-96-8

methyl 2-cyano-3-(2-naphthyl)-2-[(2-naphthyl)methyl]propionate

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 2-bromomethylnaphthyl bromide In methanol Reflux;
100%
Stage #1: methyl 2-cyanoacetate With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 0.0333333h;
Stage #2: 2-bromomethylnaphthyl bromide In dichloromethane at 0 - 20℃;
95%
Stage #1: methyl 2-cyanoacetate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: 2-bromomethylnaphthyl bromide In N,N-dimethyl-formamide at 20℃;
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 18h;
4-bromomethyltrifluoromethylbenzene
402-49-3

4-bromomethyltrifluoromethylbenzene

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl 2-cyano-3-[4-(trifluoromethyl)phenyl]-2-{[4-(trifluoromethyl)phenyl]methyl}propionate
1202778-98-0

methyl 2-cyano-3-[4-(trifluoromethyl)phenyl]-2-{[4-(trifluoromethyl)phenyl]methyl}propionate

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium methylate In methanol at 20℃;
Stage #2: 4-bromomethyltrifluoromethylbenzene In methanol Reflux;
100%
Stage #1: methyl 2-cyanoacetate With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 0.0333333h;
Stage #2: 4-bromomethyltrifluoromethylbenzene In dichloromethane at 0 - 20℃;
80%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃;80%
N-propargyl-2,4-bis(trifluoroacetyl)-1-naphthylamine
188976-06-9

N-propargyl-2,4-bis(trifluoroacetyl)-1-naphthylamine

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-oxo-1-(prop-2-ynyl)-6-(2,2,2-trifluoroacetyl)-4-(trifluoromethyl)-1,2-dihydrobenzo[h]quinoline-3-carbonitrile
1219604-14-4

2-oxo-1-(prop-2-ynyl)-6-(2,2,2-trifluoroacetyl)-4-(trifluoromethyl)-1,2-dihydrobenzo[h]quinoline-3-carbonitrile

Conditions
ConditionsYield
Stage #1: methyl 2-cyanoacetate With sodium In methanol at 20℃; for 0.25h;
Stage #2: N-propargyl-2,4-bis(trifluoroacetyl)-1-naphthylamine In methanol at 30℃; for 24h;
100%
1-(2-hydroxyethyl)piperazine
103-76-4

1-(2-hydroxyethyl)piperazine

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-oxopropanenitrile
15029-35-3

3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-oxopropanenitrile

Conditions
ConditionsYield
neat (no solvent);100%
(2-aminomethylpyridine)
3731-51-9

(2-aminomethylpyridine)

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-cyano-N-(pyridin-2-ylmethyl)acetamide
84951-58-6

2-cyano-N-(pyridin-2-ylmethyl)acetamide

Conditions
ConditionsYield
at 0 - 20℃; Neat (no solvent);100%
In neat (no solvent) at 20℃;
(3aR,4R,5RS,7aS)-4-[(R)-5-(tert-butyldimethylsilyloxy)hexyl]-5-(methoxymethoxy)-3a,4,5,7a-tetrahydrobenzofuran-2(3H)-one

(3aR,4R,5RS,7aS)-4-[(R)-5-(tert-butyldimethylsilyloxy)hexyl]-5-(methoxymethoxy)-3a,4,5,7a-tetrahydrobenzofuran-2(3H)-one

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

methyl (3aS,4R,5RS,7aS)-4-[(R)-5-(tert-butyldimethylsilyloxy)hexyl]-5-(methoxymethoxy)-2-oxo-2,3,3a,4,5,7a-hexahydrobenzofuran-3-carboxylate

methyl (3aS,4R,5RS,7aS)-4-[(R)-5-(tert-butyldimethylsilyloxy)hexyl]-5-(methoxymethoxy)-2-oxo-2,3,3a,4,5,7a-hexahydrobenzofuran-3-carboxylate

Conditions
ConditionsYield
Stage #1: (3aR,4R,5RS,7aS)-4-[(R)-5-(tert-butyldimethylsilyloxy)hexyl]-5-(methoxymethoxy)-3a,4,5,7a-tetrahydrobenzofuran-2(3H)-one With lithium hexamethyldisilazane In tetrahydrofuran; hexane at -78℃; for 0.166667h; Inert atmosphere;
Stage #2: methyl 2-cyanoacetate In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
100%
N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

2-cyano-N-(2-(dimethylamino)ethyl)acetamide
15029-55-7

2-cyano-N-(2-(dimethylamino)ethyl)acetamide

Conditions
ConditionsYield
In diethyl ether at 20℃; for 48h;100%

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