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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1-(3,4-DIMETHOXYPHENYL)-2-(2-METHOXYPHENOXY)PROPANE-1,3-DIOL

Cas:10535-17-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: veratrylglycerol-beta-guaiacyl ether Synonyms: veratrylglycerol-beta-guaiacyl ether;1-(3,4-DIMETHOXYPHENYL)-2-(2-METHOXYPHENOXY)-PROPANE-1,3-DIOL;1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol;2-(2-Methoxyphenoxy)

10535-17-8 veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

veratrylglycerol-beta-guaiacyl ether CAS 10535-17-8

Cas:10535-17-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 10535-17-8 with competitive price

Cas:10535-17-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

veratrylglycerol-beta-guaiacyl ether CAS:10535-17-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qual

veratrylglycerol-beta-guaiacyl ether CAS:10535-17-8

Cas:10535-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-

Cas:10535-17-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

Cas:10535-17-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

10535-17-8

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol 5g

Cas:10535-17-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol Application:1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Other

inquiry

DB BIOTECH CO., LTD

best seller Application:API

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

1-(3,4-Dimethoxy-phenyl)-2-(2-methoxy-phenoxy)-propane-1,3-diol

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

10535-17-8

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:50mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any por

Veratrylglycerol-Beta-Guaiacyl Ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol 10535-17-8

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

veratrylglycerol-beta-guaiacyl ether

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

Cas:10535-17-8

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol; ethyl acetate for 1h;100%
With sodium tetrahydroborate In methanol at 25℃; for 4h;76%
With sodium tetrahydroborate
With sodium tetrahydroborate In ethanol at 20℃; for 15h;
ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate
94687-10-2

ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;89%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; Inert atmosphere;78%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3h; Inert atmosphere; Reflux;46%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; for 3h;
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;
C21H26O6

C21H26O6

acetic acid
64-19-7

acetic acid

A

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

C

3-acetoxy-2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-propanone
32565-77-8

3-acetoxy-2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-propanone

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In water at 60℃; for 24h;A 8%
B 53%
C 13%
C21H26O6

C21H26O6

A

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; water at 80℃; for 15h; Temperature; Solvent;A 18%
B 30%
<2-Methoxy-phenoxy>-veratroyl-essigsaeure-aethylester
94757-79-6

<2-Methoxy-phenoxy>-veratroyl-essigsaeure-aethylester

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
2-methoxyphenoxy-3',4'-dimethoxyacetophenone
22675-96-3

2-methoxyphenoxy-3',4'-dimethoxyacetophenone

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3
2: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water; 1,4-dioxane / 23 h
2: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
2: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
2-Bromo-1-(3,4-dimethoxyphenyl)ethanone
1835-02-5

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 2 h / Reflux
2: potassium carbonate / water; 1,4-dioxane / 23 h
3: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 20 °C
2: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
3: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
2-methoxy-phenol
90-05-1

2-methoxy-phenol

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
3: sodium tetrahydroborate / ethanol / 6 h / 80 °C
4: potassium carbonate / acetone / 4.5 h / Reflux
5: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
ethyl 2-bromo-3-(3,4-dimethoxy phenyl)-3-oxopropanoate
56606-57-6

ethyl 2-bromo-3-(3,4-dimethoxy phenyl)-3-oxopropanoate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylformamide
2: LiAlH4
View Scheme
ethyl 3,4-dimethoxybenzoylacetate
4687-37-0

ethyl 3,4-dimethoxybenzoylacetate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Br2 / CHCl3
2: dimethylformamide
3: LiAlH4
View Scheme
1-(3-methoxyphenyl)ethylene glycol-β-guaiacyl ether

1-(3-methoxyphenyl)ethylene glycol-β-guaiacyl ether

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / ethanol / 6 h / 80 °C
2: potassium carbonate / acetone / 4.5 h / Reflux
3: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-ol

2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-ol

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / ethanol / 6 h / 80 °C
2: potassium carbonate / acetone / 4.5 h / Reflux
3: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
1-(3-methoxylphenyl)-2-(2-methoxyphenoxy)ethanone

1-(3-methoxylphenyl)-2-(2-methoxyphenoxy)ethanone

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / methanol / 4 h / 25 °C
2: sodium tetrahydroborate / ethanol / 6 h / 80 °C
3: potassium carbonate / acetone / 4.5 h / Reflux
4: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-one
19513-80-5

2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)ethan-1-one

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / methanol / 4 h / 25 °C
2: sodium tetrahydroborate / ethanol / 6 h / 80 °C
3: potassium carbonate / acetone / 4.5 h / Reflux
4: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
C11H13BrO4

C11H13BrO4

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
2-(2-methoxyphenoxy)-1-phenylethan-1-ol

2-(2-methoxyphenoxy)-1-phenylethan-1-ol

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / ethanol / 6 h / 80 °C
2: potassium carbonate / acetone / 4.5 h / Reflux
3: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
guaiacylglycerol-β-guaiacyl ether
7382-59-4

guaiacylglycerol-β-guaiacyl ether

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium t-butanolate; oxygen / tert-butyl alcohol / 16 h / 30 °C / 760.05 Torr / Green chemistry
2.1: potassium carbonate / acetone / 0.5 h / Reflux
2.2: 12 h / Reflux
3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
ethyl 3-hydroxy-2-(2-methoxyphenoxy)-3-phenylpropanoate

ethyl 3-hydroxy-2-(2-methoxyphenoxy)-3-phenylpropanoate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
2.1: sodium t-butanolate; oxygen / tert-butyl alcohol / 16 h / 30 °C / 760.05 Torr / Green chemistry
3.1: potassium carbonate / acetone / 0.5 h / Reflux
3.2: 12 h / Reflux
4.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
ethyl 2-(2'-methoxyphenoxy)-3-hydroxy-3-(4''-hydroxy-3''-methoxyphenyl) propanoate

ethyl 2-(2'-methoxyphenoxy)-3-hydroxy-3-(4''-hydroxy-3''-methoxyphenyl) propanoate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
2.1: sodium t-butanolate; oxygen / tert-butyl alcohol / 16 h / 30 °C / 760.05 Torr / Green chemistry
3.1: potassium carbonate / acetone / 0.5 h / Reflux
3.2: 12 h / Reflux
4.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
ethyl 2-(2-methoxyphenoxy)acetate
13078-21-2

ethyl 2-(2-methoxyphenoxy)acetate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / 45 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C / Inert atmosphere; Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 1.17 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 60 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: diisopropylamine; n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
2: sodium tetrahydroborate / tetrahydrofuran; water / 20 °C
View Scheme
2-(2-methoxyphenoxy)-1-phenylpropane-1,3-diol
227300-29-0

2-(2-methoxyphenoxy)-1-phenylpropane-1,3-diol

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium t-butanolate; oxygen / tert-butyl alcohol / 16 h / 30 °C / 760.05 Torr / Green chemistry
2.1: potassium carbonate / acetone / 0.5 h / Reflux
2.2: 12 h / Reflux
3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1.5 h / -78 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 60 °C
View Scheme
1-(3,4-dimethoxyphenyl)ethanone
1131-62-0

1-(3,4-dimethoxyphenyl)ethanone

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: bromine / ethanol / 2 h / 20 °C
2: potassium carbonate / acetone / 2 h / Reflux
3: potassium carbonate / water; 1,4-dioxane / 23 h
4: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 4 steps
1: pyridinium perbromide hydrobromide / ethyl acetate / 3 h / 20 °C
2: potassium carbonate / acetone / 20 °C
3: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
4: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane for 14h; Solvent; Reagent/catalyst; Temperature; Concentration;98%
With hydrogenchloride; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; oxygen; nitric acid In water; acetonitrile at 45℃; under 760.051 Torr; for 20h; Reagent/catalyst; Solvent; Temperature; Time;95%
With tert.-butylnitrite; oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 2-methoxy-ethanol at 80℃; for 14h;95%
methanol
67-56-1

methanol

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

1,2-Dimethoxy-4-<2-(2-methoxy-phenoxy)-3-hydroxy-1-methoxy-propyl>-benzol
96767-32-7

1,2-Dimethoxy-4-<2-(2-methoxy-phenoxy)-3-hydroxy-1-methoxy-propyl>-benzol

Conditions
ConditionsYield
With manganese(ll) chloride at 180℃; for 0.05h; Microwave irradiation;96%
With hydrogenchloride
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

β-hydroxy-3,4-dimethoxy-α-(2-methoxyphenoxy)benzenepropanoic acid

β-hydroxy-3,4-dimethoxy-α-(2-methoxyphenoxy)benzenepropanoic acid

Conditions
ConditionsYield
With 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; sodium hydrogencarbonate; sodium carbonate In water; acetonitrile pH=10; Electrochemical reaction; chemoselective reaction;91%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

2-(2-methoxyphenoxy)ethanol
18181-71-0

2-(2-methoxyphenoxy)ethanol

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

Conditions
ConditionsYield
With tetrabutylphosphonium dimethyl phosphate; 2,4,6-Triisopropylthiophenol; [Ir(2-(2,4-difluorophenyl)-4-(trifluoromethyl)pyridine)2(5,5'-bis(trifluoromethyl)-2,2'-bipyridine)]PF6 In toluene at 20℃; for 24h; Glovebox; Sealed tube; Irradiation;A 65%
B 89%
With hydridochlorotris(triphenylphosphine)ruthenium(II); [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In o-xylene at 160℃; for 4h; Inert atmosphere; Glovebox;A 77 %Chromat.
B 75 %Chromat.
di-tert-butyl-diazodicarboxylate
870-50-8

di-tert-butyl-diazodicarboxylate

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

C19H30N2O7

C19H30N2O7

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

Conditions
ConditionsYield
With pyridine; tetrabutyl-ammonium chloride; cerium triflate at 20℃; for 24h; Glovebox; Sealed tube; Irradiation;A 71%
B 81%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

2-methoxy-phenol
90-05-1

2-methoxy-phenol

B

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With oxygen; sodium t-butanolate In tert-butyl alcohol at 30℃; under 760.051 Torr; for 16h; Green chemistry; chemoselective reaction;A 78%
B 87 %Spectr.
Multi-step reaction with 2 steps
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite; sodium sulfate / 1.5 h / Milling; Green chemistry
2: sodium hydroxide / 2 h / Milling; Green chemistry
View Scheme
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

2-methoxy-phenol
90-05-1

2-methoxy-phenol

B

1-(3,4-dimethoxyphenyl)ethanone
1131-62-0

1-(3,4-dimethoxyphenyl)ethanone

Conditions
ConditionsYield
With 2C7H13N2O3S(1+)*H4P2Mo18O62(2-); oxygen In ethanol at 140℃; under 3750.38 Torr; for 14h;A 75.8%
B 24.6%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With water; [methyl-1H-imidazolium] chloride at 150℃; for 1h; Sealed vial;73.1%
With hydrogen; sodium t-butanolate; bis(1,5-cyclooctadiene)nickel(0); 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride In toluene at 50℃; under 750.075 Torr; for 16h; Product distribution / selectivity; Inert atmosphere;24 %Chromat.
With bis(1,5-cyclooctadiene)nickel (0); hydrogen; sodium t-butanolate; 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride In m-xylene at 100℃; for 2h;89 %Chromat.
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

B

2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-oxo-2-propene
62080-95-9

2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-oxo-2-propene

Conditions
ConditionsYield
With 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; hydrogen bromide; oxygen; nitric acid In water; acetonitrile at 20℃; for 24h;A 72%
B 11%
Stage #1: 1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol With 1,10-Phenanthroline; potassium carbonate; copper(I) bromide; diethylazodicarboxylate In toluene at 20℃; for 0.25h;
Stage #2: With oxygen In toluene at 90℃; under 760.051 Torr; for 1.5h; chemoselective reaction;
A 59%
B 31%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

Conditions
ConditionsYield
With oxygen; copper(l) chloride; palladium dichloride In dimethyl sulfoxide at 120℃; under 760.051 Torr; for 10h;71%
With [bis(acetoxy)iodo]benzene; oxygen In acetic acid at 80℃; under 760.051 Torr; for 24h; Solvent; chemoselective reaction;34%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; copper In neat (no solvent) at 100℃; for 18h; Reagent/catalyst; Solvent;32%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene; oxygen In ethyl acetate at 80℃; under 760.051 Torr; for 24h; chemoselective reaction;69%
With 1,10-Phenanthroline; oxygen; copper diacetate; potassium hydroxide In dimethyl sulfoxide at 140℃; under 3000.3 Torr; for 2h; Autoclave;49%
Multi-step reaction with 2 steps
1: [bis(acetoxy)iodo]benzene; oxygen / acetic acid / 24 h / 80 °C / 760.05 Torr
2: [bis(acetoxy)iodo]benzene; oxygen / 24 h / 100 °C / 760.05 Torr
View Scheme
Multi-step reaction with 2 steps
1: [bis(acetoxy)iodo]benzene; oxygen / 24 h / 100 °C / 760.05 Torr
2: [bis(acetoxy)iodo]benzene; oxygen / 24 h / 100 °C / 760.05 Torr
View Scheme
With water; potassium hydroxide at 20℃; for 12h; Electrolysis;96.7 %Chromat.
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

acetic acid
64-19-7

acetic acid

A

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol diacetate
35863-57-1

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol diacetate

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

C

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propyl acetate
113303-19-8

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propyl acetate

D

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With oxygen at 170℃; for 3h; Further byproducts given;A 66%
B 7.6%
C 2.2%
D 9.9%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

acetic acid
64-19-7

acetic acid

A

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol diacetate
35863-57-1

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol diacetate

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

C

Acetic acid 1-(3,4-dimethoxy-phenyl)-3-hydroxy-2-(2-methoxy-phenoxy)-propyl ester

Acetic acid 1-(3,4-dimethoxy-phenyl)-3-hydroxy-2-(2-methoxy-phenoxy)-propyl ester

D

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With oxygen at 170℃; for 3h; Further byproducts given;A 66%
B 7.6%
C n/a
D 9.9%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

B

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene; oxygen at 100℃; under 760.051 Torr; for 24h; Solvent; chemoselective reaction;A 10%
B 63%
With sodium hydroxide In water at 120℃; for 43h; Sealed tube;
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

ethyl 3,4-dimethoxyphenyl ketone
1835-04-7

ethyl 3,4-dimethoxyphenyl ketone

Conditions
ConditionsYield
Stage #1: 1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol With D-glucose; 5 mol% Pd/C In water; ethyl acetate at 80℃; for 12h;
Stage #2: With potassium carbonate In water; ethyl acetate at 80℃; for 3h;
Stage #3: With formic acid; ammonium formate In water; ethyl acetate at 80℃; for 4h;
62%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

ethyl 3,4-dimethoxyphenyl ketone
1835-04-7

ethyl 3,4-dimethoxyphenyl ketone

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

C

1-(3,4-dimethoxyphenyl)ethanone
1131-62-0

1-(3,4-dimethoxyphenyl)ethanone

Conditions
ConditionsYield
With C32H25Cl2N6O2Rh2(1+)*Cl(1-); sodium hydroxide In water at 110℃; for 18h; Inert atmosphere;A 33%
B 61%
C 26%
With C32H25Cl2N6O2Rh2(1+)*Cl(1-); sodium hydroxide In water at 110℃; for 18h; Inert atmosphere; Green chemistry;A 33%
B 61%
C 26%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

formic acid
64-18-6

formic acid

B

ortho-methoxyphenyl formate
118316-02-2

ortho-methoxyphenyl formate

C

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

D

2-methoxy-phenol
90-05-1

2-methoxy-phenol

E

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; bis(acetylacetonato) oxovanadium(IV) In acetonitrile at 25 - 40℃; under 760.051 Torr; for 8h; Irradiation; Sealed tube;A 20%
B 39%
C 48%
D 15%
E 46%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

Conditions
ConditionsYield
With sodium persulfate; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; palladium diacetate In N,N-dimethyl-formamide at 20℃; for 15h; Irradiation; chemoselective reaction;A 47%
B 36%
With iron(III)-acetylacetonate; oxygen; potassium carbonate; sodium hydroxide In toluene at 60℃; for 20h;A 19%
B 8%
With benzotriazol-1-ol In various solvent(s) for 20h; Product distribution; Further Variations:; Reagents; reaction type; Electrochemical reaction;
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

3-hydroxy-2-(2-methoxyphenoxy)-1-phenyl-1-propanone
99634-01-2

3-hydroxy-2-(2-methoxyphenoxy)-1-phenyl-1-propanone

B

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With water; dihydrogen peroxide In aq. phosphate buffer; ethanol at 75℃; for 4h; Sealed tube;A 26%
B 45%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

benzene-1,2-diol
120-80-9

benzene-1,2-diol

Conditions
ConditionsYield
With hydrogenchloride; water at 250℃; under 37503.8 Torr; for 3h; Reagent/catalyst; Sealed tube; Inert atmosphere;42%
With hydrogenchloride In water at 275℃; under 75007.5 Torr; for 3h; Sealed tube; Inert atmosphere;30 %Spectr.
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

3,4-dimethoxyaniline
6315-89-5

3,4-dimethoxyaniline

Conditions
ConditionsYield
With sodium azide; trifluoroacetic acid In hexane at 40℃; for 4h; Sealed tube;40%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

acetic acid
64-19-7

acetic acid

A

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

C

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propyl acetate
113303-19-8

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propyl acetate

D

Veratric acid
93-07-2

Veratric acid

Conditions
ConditionsYield
With oxygen In water at 170℃; for 3h; Further byproducts given;A 20%
B 35%
C 12%
D 16%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

A

2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-oxo-2-propene
62080-95-9

2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-oxo-2-propene

B

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane; 1-methyl-1H-imidazole; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; copper(II) bis(trifluoromethanesulfonate); 4,4′-di-(tert-butyl)-2,2′-bipyridyl In acetonitrile at 60℃; for 24h;A 21%
B 24%
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

2-(2-Methoxyphenoxy)-1-(3-hydroxy-4-methoxyphenyl)-propandiol-(1,3)
22313-79-7

2-(2-Methoxyphenoxy)-1-(3-hydroxy-4-methoxyphenyl)-propandiol-(1,3)

Conditions
ConditionsYield
With sodium metabisulfite; sodium hydroxide at 180℃; for 3h;
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

2-(2-Hydroxyphenoxy)-1-(3-hydroxy-4-methoxyphenyl)-propandiol-(1,3)
22313-80-0

2-(2-Hydroxyphenoxy)-1-(3-hydroxy-4-methoxyphenyl)-propandiol-(1,3)

Conditions
ConditionsYield
With sodium metabisulfite; sodium hydroxide at 180℃; for 3h;
1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol
10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

2-(2-Hydroxy-phenoxy)-1-(3,4-dimethoxyphenyl)-propandiol-(1,3)
22313-78-6

2-(2-Hydroxy-phenoxy)-1-(3,4-dimethoxyphenyl)-propandiol-(1,3)

Conditions
ConditionsYield
With sodium metabisulfite; sodium hydroxide at 180℃; for 3h;

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