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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Thiophenecarbonitrile Manufacturer/High quality/Best price/In stock

Cas:1641-09-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 1641-09-4 with best price

Cas:1641-09-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

chemical intermediate 3-Thiophenecarbonitrile/CAS:1641-09-4

Cas:1641-09-4

Min.Order:1 Gram

FOB Price: $98.0 / 121.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

3-Thiophenecarbonitrile CAS:1641-09-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

3-Thiophenecarbonitrile CAS:1641-09-4

Cas:1641-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-Cyanothiophene

Cas:1641-09-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

cas:1641-09-4

Cas:1641-09-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM 1641-09-4 3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

3-Thiophenecarbonitrile CAS NO.: 1641-09-4

Cas:1641-09-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

3-Thiophenecarbonitrile Basic information Product Name: 3-Thiophenecarbonitrile Synonyms: BUTTPARK 96\11-31;3-CYANOTHIOPHENE;3-THIOPHENECARBONITRILE;THIOPHENE-3-CARBONITRILE;Thiophene-3-carbonitrile 97%;3-Thiophenecarbonitr;3-Cyanothiophene, T

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Thiophenecarbonitrile Cas no.1641-09-4 98%

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Greenutra Resource Inc

3-CyanothiopheneAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

3-Cyanothiophene

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Cyanothiophene

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3-Cyanothiophene

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 3-Thiophenecarbonitrile 1g

Cas:1641-09-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

3-Cyanothiophene

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Trading Company

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

3-Thiophenecarbonitrile cas 1641-09-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3-Thiophenecarbonitrile cas 1641-09-4

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:Clear colorless liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

3-Cyanothiophene

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Thiophenecarbonitrile

Cas:1641-09-4

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

3-hydroxymethyl-thiophene
71637-34-8

3-hydroxymethyl-thiophene

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With ammonia; oxygen In tert-Amyl alcohol; water at 100℃; under 3750.38 Torr; for 5h; Autoclave; High pressure;99%
With ammonia; oxygen In 1,4-dioxane for 3h; Reflux;91%
With ammonium hydroxide; copper(l) iodide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; N-Phenylglycine; sodium hydroxide In methanol at 50℃; for 24h; Cooling with ice;90%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; ammonia; oxygen; copper(II) nitrate In water; dimethyl sulfoxide at 80℃; under 760.051 Torr; for 5h;83%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; O-benzenesulfonyl-acetohydroxamic acid ethyl ester In dichloromethane at 23℃; for 24h; Inert atmosphere;98%
With hydroxylamine hydrochloride In methanol; water at 20℃; for 18h; Irradiation;89%
With ammonium hydroxide; iodine88%
2-thiophenecarboxaldehyde N,N-dimethylhydrazone
69819-67-6

2-thiophenecarboxaldehyde N,N-dimethylhydrazone

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With HOF* CH3CN at 0℃;96%
3-Bromothiophene
872-31-1

3-Bromothiophene

sodium cyanide
773837-37-9

sodium cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With tri-tert-butyl phosphine; [Pd2(dba)5]; zinc In tetrahydrofuran; acetonitrile at 70℃; for 2h;93%
N,N-Dimethyl-N'-[1-thiophen-3-yl-meth-(E)-ylidene]-hydrazine

N,N-Dimethyl-N'-[1-thiophen-3-yl-meth-(E)-ylidene]-hydrazine

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 2h;91%
3-Bromothiophene
872-31-1

3-Bromothiophene

K4[Fe(CN)6]

K4[Fe(CN)6]

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With sodium carbonate; potassium iodide; N,N`-dimethylethylenediamine; copper(II) bis(tetrafluoroborate) In N,N-dimethyl acetamide at 140℃; for 16h;90%
With sodium carbonate; palladium diacetate at 140℃; for 16h;87%
2,2-diazido-1,2-di(thiophen-3-yl)ethanone

2,2-diazido-1,2-di(thiophen-3-yl)ethanone

benzylamine
100-46-9

benzylamine

A

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

B

N-benzylthiophene-3-carboxamide
1048915-76-9

N-benzylthiophene-3-carboxamide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 24h;A 33 mg
B 89%
Thien-3-ylboronic acid
6165-69-1

Thien-3-ylboronic acid

benzyl thiocyanate
3012-37-1

benzyl thiocyanate

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With copper(I) thiophene-2-carboxylate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane at 100℃; for 12h;83%
3-Bromothiophene
872-31-1

3-Bromothiophene

sodium cyanide
143-33-9

sodium cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With trans-chloro(1-naphthyl)bis-(triphenylphosphine)nickel(II); triphenylphosphine In ethanol for 1h; Heating;82%
Stage #1: 3-Bromothiophene; sodium cyanide With potassium iodide; N,N`-dimethylethylenediamine; copper(l) iodide In toluene at 110℃; for 24h;
Stage #2: With ammonia In water; ethyl acetate; toluene at 25℃; for 0.166667h;
3-Bromothiophene
872-31-1

3-Bromothiophene

potassiumhexacyanoferrate(II) trihydrate

potassiumhexacyanoferrate(II) trihydrate

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); tris(2-morpholinophenyl)phosphine; potassium carbonate In water; tert-butyl alcohol at 85℃; for 5h; Schlenk technique; Inert atmosphere;82%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

3-thiophenecarboxylic acid phenyl ester
14596-83-9

3-thiophenecarboxylic acid phenyl ester

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); sodium formate; 1,2-bis-(dicyclohexylphosphino)ethane In toluene at 170℃; for 48h; Glovebox; Sealed tube;82%
thiophene-3-diazonium o-benzenedisulfonimide

thiophene-3-diazonium o-benzenedisulfonimide

tetra-n-butylammonium cyanide
10442-39-4

tetra-n-butylammonium cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
In acetonitrile at 22℃; for 1h; Sandmeyer Reaction;81%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

2,4,6-tris(thiophen-3-yloxy)-1,3,5-triazine

2,4,6-tris(thiophen-3-yloxy)-1,3,5-triazine

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)nickel (0); 1,2-bis-(dicyclohexylphosphino)ethane In 1,4-dioxane at 110℃; Inert atmosphere;81%
3-Bromothiophene
872-31-1

3-Bromothiophene

dicyanozinc
557-21-1

dicyanozinc

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide for 0.0416667h; Substitution; microwave irradiation;80%
With 1,1'-bis-(diphenylphosphino)ferrocene; zinc; tris-(dibenzylideneacetone)dipalladium(0) In N,N-dimethyl acetamide at 80℃; for 48h;
3-Bromothiophene
872-31-1

3-Bromothiophene

zinc(II) cyanide
557-21-1

zinc(II) cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With dichloro[9,9-dimethyl-4,5- bis(diphenylphosphino)xanthene]palladium (II); N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 85℃; Sealed tube;79%
3-thiophenecarbaldoxime hydrochloride

3-thiophenecarbaldoxime hydrochloride

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With 3 A molecular sieve at 135 - 350℃; under 0.01 Torr; for 0.25h; Pyrolysis;77%
With acetic anhydride for 48h; Dehydration; Heating;
3-thienyl iodide
10486-61-0

3-thienyl iodide

potassium hexacyanoferrate(II) trihydrate

potassium hexacyanoferrate(II) trihydrate

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With tetrabutylammomium bromide; copper(II) acetate monohydrate In water at 20 - 140℃; Microwave irradiation;77%
3-carbamoylthiophene
51460-47-0

3-carbamoylthiophene

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
at 285℃; for 1h; Temperature;74%
3-Bromothiophene
872-31-1

3-Bromothiophene

copper(l) cyanide

copper(l) cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
Stage #1: 3-Bromothiophene; copper(l) cyanide In N,N-dimethyl-formamide for 4h; Reflux;
Stage #2: With hydrogenchloride; iron(III) chloride In water; N,N-dimethyl-formamide at 70℃; for 0.75h;
72%
In N,N-dimethyl-formamide for 16h; Reflux;72%
3-(chloromethyl)thiophene
2746-23-8

3-(chloromethyl)thiophene

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With sodium azide; palladium diacetate; XPhos In acetone at 80℃; for 12h; Inert atmosphere;72%
3-chlorothiophene
17249-80-8

3-chlorothiophene

zinc(II) cyanide
557-21-1

zinc(II) cyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
Stage #1: zinc(II) cyanide With aluminum oxide; Ni(xantphos)(o-tolyl)Cl for 1h; Schlenk technique; Inert atmosphere; Sealed tube;
Stage #2: 3-chlorothiophene In 1-methyl-pyrrolidin-2-one at 20℃; for 24h; Schlenk technique; Inert atmosphere;
72%
3-chlorothiophene
17249-80-8

3-chlorothiophene

potassiumhexacyanoferrate(II) trihydrate

potassiumhexacyanoferrate(II) trihydrate

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With C42H58NO3PPdS(2-); potassium acetate; tert-butyl XPhos In 1,4-dioxane; water at 100℃; for 1h; Inert atmosphere; Sealed tube;71%
3-Bromothiophene
872-31-1

3-Bromothiophene

potassium ferrocyanide

potassium ferrocyanide

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With 10% Pd/C; sodium fluoride; potassium iodide In PEG4000; water at 160℃; for 2h; Microwave irradiation;70%
With dichloro[bis{1-(dicyclohexylphosphanyl)piperidine}]palladium; sodium carbonate In 1-methyl-pyrrolidin-2-one at 140℃; for 24h; Inert atmosphere;56%
2-thiophenemethanol
636-72-6

2-thiophenemethanol

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With potassium phosphate; ammonium formate In acetonitrile at 115℃; for 16h; Sealed tube; Green chemistry;68%
3-ethynylthiophene
67237-53-0

3-ethynylthiophene

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With trimethylsilylazide; silver carbonate In dimethyl sulfoxide at 100℃; for 12h;63%
1-(thiophen-3-yl)-ethanone
1468-83-3

1-(thiophen-3-yl)-ethanone

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With oxygen; copper(l) cyanide In dimethyl sulfoxide at 150℃;63%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

1-(thiophene-3-carbonyl)piperidine-2,6-dione

1-(thiophene-3-carbonyl)piperidine-2,6-dione

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With palladium diacetate; cyclohexyldiphenylphosphine In 1,4-dioxane at 150℃; for 16h; Inert atmosphere; Schlenk technique; chemoselective reaction;62%
(E)-benzyl 2-diazo-5-oxopent-3-enoate
1616777-26-4

(E)-benzyl 2-diazo-5-oxopent-3-enoate

3-(1-azidovinyl)thiophene

3-(1-azidovinyl)thiophene

A

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

B

benzyl (E)-2-(3-oxoprop-1-en-1-yl)-5-(thiophen-3-yl)-3,4-dihydro-2H-pyrrole-2-carboxylate

benzyl (E)-2-(3-oxoprop-1-en-1-yl)-5-(thiophen-3-yl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Conditions
ConditionsYield
With dirhodium tetraacetate In dichloromethane at 25℃; for 12h; Inert atmosphere;A n/a
B 62%
thiophen-3-yl-acetic acid
6964-21-2

thiophen-3-yl-acetic acid

3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Conditions
ConditionsYield
With oxygen; copper(II) trifluoroacetate; urea In dimethyl sulfoxide at 120℃; for 21h; Green chemistry;53%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

3-carbamoylthiophene
51460-47-0

3-carbamoylthiophene

Conditions
ConditionsYield
With copper(l) iodide; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene In nitromethane; water at 20 - 100℃; for 1h;100%
With [RuH(tBu-PNP(-))(CO)]; water In tert-butyl alcohol at 20℃; for 24h;99%
With manganese(IV) oxide; water In isopropyl alcohol at 70℃; under 5171.62 Torr; for 0.333333h;98%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

3-(4-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine
78539-93-2

3-(4-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine

1-(4-chlorophenyl)-3-(thiophen-3-yl)imidazo[1,5-a]pyridine

1-(4-chlorophenyl)-3-(thiophen-3-yl)imidazo[1,5-a]pyridine

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In 1,2-dichloro-ethane; 1,2-dichloro-benzene at 160℃; for 16h; Sealed tube;99%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

N-hydroxythiophene-3-formamidine
58905-71-8

N-hydroxythiophene-3-formamidine

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium hydrogencarbonate In methanol for 5h; Reflux;99%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

5-(thiophen-3-yl)-1H-tetrazole
59918-86-4

5-(thiophen-3-yl)-1H-tetrazole

Conditions
ConditionsYield
With sodium azide; ammonium chloride In N,N-dimethyl-formamide for 0.25h; Cycloaddition; microwave irradiation;98%
Stage #1: 3-thiophenecarbonitrile With sodium azide; zinc dibromide In N,N-dimethyl-formamide Heating / reflux;
Stage #2: With hydrogenchloride In water; N,N-dimethyl-formamide at 20℃;
98%
With sodium azide; cerium(III) chloride heptahydrate In water; isopropyl alcohol at 160℃; for 1h; Microwave irradiation;98%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

C17H25B2NO4S
916454-58-5

C17H25B2NO4S

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In pentane at 20℃; for 1.5h; Schlenk technique; Inert atmosphere;98%
(1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 20℃; for 0.5h;85%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

nitromethane
75-52-5

nitromethane

(Z)-2-nitro-1-(thiophen-3-yl)ethen-1-amine

(Z)-2-nitro-1-(thiophen-3-yl)ethen-1-amine

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; copper(l) iodide; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene at 85℃; for 1h; Aza-Henry Reaction; Molecular sieve;95%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

Quinoline N-oxide
1613-37-2

Quinoline N-oxide

N-(quinolin-2-yl)thiophene-3-carboxamide

N-(quinolin-2-yl)thiophene-3-carboxamide

Conditions
ConditionsYield
With lignin sulfonic acid for 0.333333h; Microwave irradiation;94%
With toluene-4-sulfonic acid at 150℃; for 12h;88%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

1-iodocyclohexane
626-62-0

1-iodocyclohexane

3-cyano-2-cyclohexylthiophene

3-cyano-2-cyclohexylthiophene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); 1,3-bis-(diphenylphosphino)propane; caesium carbonate at 110℃; for 36h; Inert atmosphere; Schlenk technique; regioselective reaction;92%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

1-(4-fluorophenyl)ethanone
403-42-9

1-(4-fluorophenyl)ethanone

4-(4-fluorophenyl)-2,6-di(thiophen-3-yl)pyrimidine

4-(4-fluorophenyl)-2,6-di(thiophen-3-yl)pyrimidine

Conditions
ConditionsYield
With sodium hydroxide; copper dichloride at 120℃; for 24h; Schlenk technique; Inert atmosphere;92%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

5-nitrothiophene-3-carboxamide
36050-09-6

5-nitrothiophene-3-carboxamide

Conditions
ConditionsYield
With sulfuric acid; potassium nitrate for 16h; Ambient temperature;91%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

1-Adamantanecarboxylic acid
828-51-3

1-Adamantanecarboxylic acid

2-(1-adamantyl)-3-cyanothiophene

2-(1-adamantyl)-3-cyanothiophene

Conditions
ConditionsYield
With [Co(dyimethylglyoximate(1-))2(pyridine)2]PF6; tetrabutylammonium acetate In ethyl acetate at 40 - 44℃; for 30h; Irradiation; Schlenk technique; Inert atmosphere;91%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

N-allyl-N-phenylamine
589-09-3

N-allyl-N-phenylamine

N-allyl-N-phenylthiophene-3-carboximidamide
1402238-79-2

N-allyl-N-phenylthiophene-3-carboximidamide

Conditions
ConditionsYield
Stage #1: N-allyl-N-phenylamine With trimethylaluminum In toluene at 0 - 20℃;
Stage #2: 3-thiophenecarbonitrile In toluene at 100℃;
90%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

aniline
62-53-3

aniline

N-phenyl thiophene carboxamidine-3
59918-76-2

N-phenyl thiophene carboxamidine-3

Conditions
ConditionsYield
With sodium hydride In dimethyl sulfoxide; mineral oil at 0 - 20℃; Inert atmosphere;90%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

3-chloro-aniline
108-42-9

3-chloro-aniline

C11H9ClN2S

C11H9ClN2S

Conditions
ConditionsYield
With sodium hydride In dimethyl sulfoxide; mineral oil at 0 - 20℃; Inert atmosphere;90%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

3-phenyl-[1,2,3]triazolo[1,5-a]pyridine
832-81-5

3-phenyl-[1,2,3]triazolo[1,5-a]pyridine

1-phenyl-3-(thiophen-3-yl)imidazo[1,5-a]pyridine

1-phenyl-3-(thiophen-3-yl)imidazo[1,5-a]pyridine

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In 1,2-dichloro-ethane; 1,2-dichloro-benzene at 160℃; for 16h; Sealed tube;89%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

diphenyl acetylene
501-65-5

diphenyl acetylene

6,7-diphenylthieno[3,2-c]pyridin-4(5H)-one
1444611-61-3

6,7-diphenylthieno[3,2-c]pyridin-4(5H)-one

Conditions
ConditionsYield
With potassium hexafluorophosphate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; oxygen; copper diacetate In acetic acid at 120℃; for 10h;88%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

4,4,5,5-tetramethyl-N-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(thiophen-3-ylmethyl)-1,3,2-dioxaborolan-2-amine

4,4,5,5-tetramethyl-N-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(thiophen-3-ylmethyl)-1,3,2-dioxaborolan-2-amine

Conditions
ConditionsYield
With C52H58N4P2Zn2 In neat (no solvent) at 20℃; for 0.0333333h; Green chemistry;88%
With silver hexafluoroantimonate at 60℃; for 24h; Inert atmosphere; Glovebox;82%
With [(Me3Si)2N]2Th[κ2-(N,C)-CH2Si(CH3)2N(SiMe3)] In benzene-d6 at 80℃; for 6h; Catalytic behavior; Sealed tube;75 %Spectr.
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

2-iodothiophene-3-carbonitrile
18800-01-6

2-iodothiophene-3-carbonitrile

Conditions
ConditionsYield
Stage #1: 3-thiophenecarbonitrile With 2,2,6,6-tetramethylpiperidinyl-lithium at -78℃;
Stage #2: With iodine Further stages.;
87%
Stage #1: 3-thiophenecarbonitrile With zinc(II) chloride In tetrahydrofuran at 25℃; for 0.166667h;
Stage #2: With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex In tetrahydrofuran at 60℃; for 0.333333h; Microwave irradiation;
Stage #3: With tetrakis(triphenylphosphine) palladium(0); iodine In tetrahydrofuran at 25℃; for 12h;
68%
Stage #1: 3-thiophenecarbonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.25h;
Stage #2: With N-iodo-succinimide In tetrahydrofuran
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

1-iodoadamantane
768-93-4

1-iodoadamantane

2-(1-adamantyl)-3-cyanothiophene

2-(1-adamantyl)-3-cyanothiophene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); 1,3-bis-(diphenylphosphino)propane; caesium carbonate at 110℃; for 72h; Inert atmosphere; Schlenk technique; regioselective reaction;86%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

carbon dioxide
124-38-9

carbon dioxide

3-cyanothiophene-2-carboxylic acid
58231-00-8

3-cyanothiophene-2-carboxylic acid

Conditions
ConditionsYield
With 2,3,6,7-tetramethoxy-9(10H)-anthracenone; caesium carbonate In dimethyl sulfoxide at 25℃; under 2280.15 Torr; for 18h; Irradiation; Sealed tube; regioselective reaction;86%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

thiophene-3-thiocarboxamide
24044-76-6

thiophene-3-thiocarboxamide

Conditions
ConditionsYield
Stage #1: 3-thiophenecarbonitrile With calcium hydride; tiolacetic acid at 80℃; for 1h;
Stage #2: With water In ethyl acetate at 20℃;
85%
With hydrogenchloride; O,S-diethyl-dithiophosphoric acid In ethyl acetate Ambient temperature;84%
With sodiumsulfide nonahydrate In N,N-dimethyl-formamide at 130℃; for 2.5h;82%
With pyridine; diammonium sulfide; triethylamine In water at 50℃;
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

(3-thienylmethyl)amine
27757-86-4

(3-thienylmethyl)amine

Conditions
ConditionsYield
Stage #1: 3-thiophenecarbonitrile With lithium aluminium tetrahydride In tetrahydrofuran at 20 - 50℃; for 4.33333h; Inert atmosphere;
Stage #2: With water; sodium hydroxide In tetrahydrofuran at 30℃; Inert atmosphere;
85%
With [Ru(H)(BH4)(CO)(PPh3)(3-(di-tert-butylphosphino)-N-((1-methyl-1H-imidazol-2 yl)methyl)propylamine)]; hydrogen In isopropyl alcohol at 130℃; for 3h; Inert atmosphere; Autoclave;82%
With borane-ammonia complex; C15H30Cl2CoN3P In hexane at 120℃; for 16h; Sealed tube; Inert atmosphere; chemoselective reaction;80%
3-thiophenecarbonitrile
1641-09-4

3-thiophenecarbonitrile

benzoyl chloride
98-88-4

benzoyl chloride

2-benzoylthiophene-3-carbonitrile
30011-74-6

2-benzoylthiophene-3-carbonitrile

Conditions
ConditionsYield
Stage #1: 3-thiophenecarbonitrile With zinc(II) chloride In tetrahydrofuran at 25℃; for 0.166667h;
Stage #2: With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex In tetrahydrofuran at 60℃; for 0.333333h; Microwave irradiation;
Stage #3: benzoyl chloride With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 25℃; for 12h;
85%

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