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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Triethyl phosphonoacetate Manufacturer/High quality/Best price/In stock

Cas:867-13-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Colorless oily liquid Conforms Assay ≥99%

Top purity Triethyl phosphonoacetate with high quality and best price cas:867-13-0

Cas:867-13-0

Min.Order:1 Kilogram

FOB Price: $20.0 / 50.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality diethyl ethoxycarbonylmethylphosphonate supplier in China

Cas:867-13-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Colorless to light yellow liquid Storage:Refrigerator Pac

Factory supply Triethyl phosphonoacetate CAS 867-13-0 with low price

Cas:867-13-0

Min.Order:25 Kilogram

FOB Price: $100.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

The company has a professional R & D team, mature technology, very competitive prices and stable high quality products for customers to order high quality and low price product efforts! Appearance:Clear Liquid Storage:Sealed, dry, microtherm ,

TRIETHYL PHOSPHONOACETATE

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(Ethoxycarbonylmethyl)-diethoxyphosphine oxide

Cas:867-13-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Triethyl Phosphonoacetate--

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Triethyl Phosphonoacetate 867-13-0

Cas:867-13-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 867-13-0 with best price

Cas:867-13-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Triethyl phosphonoacetateCAS867-13-0

Cas:867-13-0

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white crystalline powder Storage:Store in sealed containers

Triethyl Phosphonoacetate CAS 867-13-0 C8H18O11P3

Cas:867-13-0

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Triethyl phosphonoacetate 867-13-0

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

99% Purity Triethyl phosphonoacetate / AURORA KA-1452 / tl465

Cas:867-13-0

Min.Order:10 Gram

FOB Price: $2.9

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Triethyl phosphonoacetate CAS: 867-13-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Triethyl phosphonoacetate CAS: 867-13-0

Cas:867-13-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:867-13-0

Cas:867-13-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Email Us: admin07@hsnm.com.cn quick details of Triethyl phosphonoacetate raw liquids Product Name Triethyl phosphonoacetate CAS 867-13-0 MF C8H17O5P MW 224.19 EINECS 212-757-6 MOL File 867-13-0.mol Chemical Properties Melting point -24°

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

Ethyl 2-(diethoxyphosphoryl)acetate

Cas:867-13-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Factory Supply 867-13-0 Triethyl phosphonoacetate with best quality

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Other

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

High purity Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory SellsTriethyl phosphonoacetate

Cas:867-13-0

Min.Order:0

Negotiable

Type:Trading Company

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Siwei Development Group Ltd.

Product name: Triethyl Phosphonacetic Acid CAS No.:867-13-0 Molecule Formula:C8H17O5P Molecule Weight:224.19 Purity: 98.0% Package: 200kg/drum Description:Colorless to light yellow liquid Manufacture Standards:Enterprise Standard

High Quality Triethyl Phosphonacetic Acid

Cas:867-13-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Triethylphosphonoacetate

Cas:867-13-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Triethyl phosphonoacetate CAS: 867-13-0 MF: C8H17O5P MW: 224.19 EINECS: 212-757-6 Mol File: 867-13-0.mol Triethyl phosphonoacetate Structure Triethyl phosphonoacetate Chemical Properties Melting point -24°C B

Triethyl phosphonoacetate

Cas:867-13-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Synthetic route

ethyl bromoacetate
105-36-2

ethyl bromoacetate

triethyl phosphite
122-52-1

triethyl phosphite

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
at 60 - 80℃; for 0.5h; Arbusov reaction;100%
at 150℃; for 3h;99%
for 0.0333333h; Michaelis-Arbuzov reaction; microwave irradiation;98%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

triethyl phosphite
122-52-1

triethyl phosphite

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
In toluene at 170℃; under 7500.75 Torr; for 0.333333h; Pressure; Temperature; Arbuzov Reaction; Large scale;95%
at 120 - 165℃; for 2h;93%
for 2h; Inert atmosphere; Reflux;63%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With triethyl phosphite89.3%
triethyl phosphate
78-40-0

triethyl phosphate

ethyl bromoacetate
105-36-2

ethyl bromoacetate

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
at 140℃; for 3h;88%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With copper acetylacetonate In benzene Product distribution; Heating; other catalysts, other diazo compounds, other hydrophosphoryl compounds;83%
copper acetylacetonate In benzene for 1h; Heating;83%
With copper acetylacetonate In benzene Heating;83%
With trifluorormethanesulfonic acid In benzene Heating;2%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate; 18-crown-6 ether at 80℃; for 6h;77%
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane at 0 - 5℃; for 0.333333h;55%
With potassium carbonate In ethanol at 78℃; for 2h; Substitution; Michaelis-Becker reaction;33%
methyl vinyl ketone
78-94-4

methyl vinyl ketone

diethyl 1-iodo-1-carbethoxy-methylphosphonate
66700-63-8

diethyl 1-iodo-1-carbethoxy-methylphosphonate

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

2-(Diethoxy-phosphoryl)-5-oxo-hexanoic acid ethyl ester

2-(Diethoxy-phosphoryl)-5-oxo-hexanoic acid ethyl ester

Conditions
ConditionsYield
With triethyl borane; tri-n-butyl-tin hydride In hexane; toluene at -78℃; for 6h; Yields of byproduct given;A n/a
B 77%
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

XC(O)OC2H5

XC(O)OC2H5

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With n-butyllithium; lithium diisopropyl amide In tetrahydrofuran; hexane at -60℃;74%
2-(5-methyl-2-phenyl-4-oxazolyl)methyl-5-benzofurancarboxaldehyde
132646-34-5

2-(5-methyl-2-phenyl-4-oxazolyl)methyl-5-benzofurancarboxaldehyde

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

ethyl (E)-3-[2-(5-methyl-2-phenyl-4-oxazolylmethyl)benzofuran-5-yl]acrylate
159017-57-9

ethyl (E)-3-[2-(5-methyl-2-phenyl-4-oxazolylmethyl)benzofuran-5-yl]acrylate

Conditions
ConditionsYield
A n/a
B 74%
Methyl diethylphosphonoacetate
1067-74-9

Methyl diethylphosphonoacetate

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-oxo-1H-pyrrolo-<2,3-d>carbazole-6-carboxylate
219650-29-0

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-oxo-1H-pyrrolo-<2,3-d>carbazole-6-carboxylate

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-(E)-<(methoxycarbonyl)methylene>-1H-pyrrolo<2,3-d>carbazole-6-carboxylates
219650-31-4

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-(E)-<(methoxycarbonyl)methylene>-1H-pyrrolo<2,3-d>carbazole-6-carboxylates

C

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-(Z)-<(methoxycarbonyl)methylene>-1H-pyrrolo<2,3-d>carbazole-6-carboxylates
219650-30-3

(-)-methyl (2S,3aS,5R,11bR)-3-benzyl-2,3,3a,4,5,7-hexahydro-3,5-ethano-12-(Z)-<(methoxycarbonyl)methylene>-1H-pyrrolo<2,3-d>carbazole-6-carboxylates

Conditions
ConditionsYield
With potassium hexamethyldisilazane In tetrahydrofuran for 0.5h; Ambient temperature; Yield given;A n/a
B 64%
C n/a
Diethyl phosphonate
762-04-9, 123-22-8

Diethyl phosphonate

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With sodium In diethyl ether60%
(E)-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]cinnamaldehyde
159017-37-5

(E)-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]cinnamaldehyde

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

ethyl (E)-5-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]-2,4-pentadienoate
1026936-75-3

ethyl (E)-5-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]-2,4-pentadienoate

Conditions
ConditionsYield
A n/a
B 56%
vinyl acetate
108-05-4

vinyl acetate

diethyl 1-iodo-1-carbethoxy-methylphosphonate
66700-63-8

diethyl 1-iodo-1-carbethoxy-methylphosphonate

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

4-Acetoxy-2-(diethoxy-phosphoryl)-butyric acid ethyl ester

4-Acetoxy-2-(diethoxy-phosphoryl)-butyric acid ethyl ester

Conditions
ConditionsYield
With triethyl borane; tri-n-butyl-tin hydride In hexane; toluene at -78℃; for 6h; Yields of byproduct given;A n/a
B 38%
triethyl 2-chloro-2-phosphonoacetate
7071-12-7

triethyl 2-chloro-2-phosphonoacetate

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

(E)-ethyl 2-chloro-3-(4-methoxyphenyl)propenoate
66051-39-6

(E)-ethyl 2-chloro-3-(4-methoxyphenyl)propenoate

C

(E)-methoxyphenyl-3 chloro-2 propenoate d'ethyle
66051-40-9

(E)-methoxyphenyl-3 chloro-2 propenoate d'ethyle

Conditions
ConditionsYield
With tetramethylammonium tetrafluoroborate; 4-methoxy-benzaldehyde In N,N-dimethyl-formamide Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag; Yields of byproduct given;A 22%
B n/a
C n/a
triethyl 2-chloro-2-phosphonoacetate
7071-12-7

triethyl 2-chloro-2-phosphonoacetate

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

(E)-ethyl 2-chloro-3-(4-methoxyphenyl)propenoate
66051-39-6

(E)-ethyl 2-chloro-3-(4-methoxyphenyl)propenoate

C

(E)-methoxyphenyl-3 chloro-2 propenoate d'ethyle
66051-40-9

(E)-methoxyphenyl-3 chloro-2 propenoate d'ethyle

Conditions
ConditionsYield
With tetramethylammonium tetrafluoroborate In N,N-dimethyl-formamide Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag; Yield given;A 22%
B n/a
C n/a
triethyl 2-chloro-2-phosphonoacetate
7071-12-7

triethyl 2-chloro-2-phosphonoacetate

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate
24393-56-4

ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate

C

(Z)-ethyl 3-(4-methoxyphenyl)acrylate
51507-22-3

(Z)-ethyl 3-(4-methoxyphenyl)acrylate

Conditions
ConditionsYield
With tetramethylammonium tetrafluoroborate In N,N-dimethyl-formamide Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag; Yield given;A 14%
B n/a
C n/a
diethyl ether
60-29-7

diethyl ether

sodium diethyl phosphite
2303-76-6, 118080-94-7

sodium diethyl phosphite

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

sodium diethyl phosphite
2303-76-6, 118080-94-7

sodium diethyl phosphite

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With hexane
With ligroine
With ethanol
sodium diethyl phosphite
2303-76-6, 118080-94-7

sodium diethyl phosphite

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

benzene
71-43-2

benzene

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

sodium diethyl phosphite
2303-76-6, 118080-94-7

sodium diethyl phosphite

ethyl bromoacetate
105-36-2

ethyl bromoacetate

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With benzene
ethanol
64-17-5

ethanol

dichlorophosphoryl-acetyl chloride
34164-06-2

dichlorophosphoryl-acetyl chloride

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With pyridine In diethyl ether
diethyl ester of 2,2-diethoxyethenephosphonic acid
34159-39-2

diethyl ester of 2,2-diethoxyethenephosphonic acid

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With sulfuric acid; water
2-Diethoxyphosphoryl-3-dimethylaminoacrylsaeure-ethylester
74119-48-5

2-Diethoxyphosphoryl-3-dimethylaminoacrylsaeure-ethylester

A

benzoimidazole
51-17-2

benzoimidazole

B

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With 1,2-diamino-benzene In ethanol Heating;
diethyl phosphorylchloridite
589-57-1

diethyl phosphorylchloridite

ethyl acetate
141-78-6

ethyl acetate

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
Yield given. Multistep reaction. Further byproducts given;
Diazoethan
1117-96-0

Diazoethan

carbon dioxide
124-38-9

carbon dioxide

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

methyl iodide
74-88-4

methyl iodide

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
In diethyl ether at 0℃; for 0.5h;
2-Diethoxyphosphoryl-3-dimethylaminoacrylsaeure-ethylester
74119-48-5

2-Diethoxyphosphoryl-3-dimethylaminoacrylsaeure-ethylester

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

A

benzoimidazole
51-17-2

benzoimidazole

B

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
In ethanol Heating;
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

Diethyl carbonate
105-58-8

Diethyl carbonate

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine 1.) hexane, THF, -78 deg C, 5 min, 2.) THF, -78 deg C --> 0 deg C; Yield given. Multistep reaction;
With n-butyllithium 1.) THF, hexane, -55 deg C, 20 min, 2.) THF, hexane, -55 deg C, 30 min; Yield given. Multistep reaction;
ethyl bromoacetate
105-36-2

ethyl bromoacetate

triethyl phosphite
122-52-1

triethyl phosphite

A

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

B

phosphoric acid 1-ethoxy-vinyl ester diethyl ester
63720-98-9

phosphoric acid 1-ethoxy-vinyl ester diethyl ester

Conditions
ConditionsYield
In benzene for 8h; Heating;
In benzene for 8h; Heating;
ethyl 2,2-dichloro-2-diethoxyphosphorylacetate
5823-12-1

ethyl 2,2-dichloro-2-diethoxyphosphorylacetate

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 7 percent / p-methoxybenzaldehyde, Me4NBF4 / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag
2: 22 percent / Me4NBF4, p-methoxybenzaldehyde / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag
View Scheme
Multi-step reaction with 2 steps
1: 7 percent / p-methoxybenzaldehyde, Me4NBF4 / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag
2: 22 percent / Me4NBF4 / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag
View Scheme
formaldehyd
50-00-0

formaldehyd

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

ethyl 2-diethoxyphosphinoylacrylate
20345-61-3

ethyl 2-diethoxyphosphinoylacrylate

Conditions
ConditionsYield
Stage #1: formaldehyd; diethoxyphosphoryl-acetic acid ethyl ester With piperidine In methanol at 80℃; for 36h;
Stage #2: With toluene-4-sulfonic acid In toluene for 16h; Dean-Stark; Reflux;
100%
Stage #1: formaldehyd With piperidine In methanol for 0.5h; Heating;
Stage #2: diethoxyphosphoryl-acetic acid ethyl ester In methanol for 70h; Heating;
73%
piperidine In methanol Heating;60%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

cyclohexanone
108-94-1

cyclohexanone

ethyl cyclohexylideneacetate
1552-92-7

ethyl cyclohexylideneacetate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil for 1h;
Stage #2: cyclohexanone In tetrahydrofuran; mineral oil for 18h;
100%
With sodium hydride In tetrahydrofuran for 8h;98%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With 15-crown-5; sodium hydride In tetrahydrofuran; mineral oil at 0℃;
Stage #2: cyclohexanone In tetrahydrofuran; mineral oil at -40 - 20℃;
97%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

heptanal
111-71-7

heptanal

ethyl 2-nonenoate
17463-01-3

ethyl 2-nonenoate

Conditions
ConditionsYield
With triethylamine; magnesium bromide In tetrahydrofuran at 25℃; for 12h;100%
(i) NaH, Et2O, (ii) /BRN= 1560236/; Multistep reaction;
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

4-heptanone
123-19-3

4-heptanone

ethyl 3-propylhex-2-enoate
10297-63-9

ethyl 3-propylhex-2-enoate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 20℃;
Stage #2: 4-heptanone at 20℃; for 24h; Reflux;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Schlenk technique; Inert atmosphere;
Stage #2: 4-heptanone In tetrahydrofuran; mineral oil at 20℃; Schlenk technique; Inert atmosphere;
88%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester; 4-heptanone With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 0.333333h; Inert atmosphere; Schlenk technique;
Stage #2: In tetrahydrofuran; mineral oil for 20h; Reflux;
86%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

diethylphosphonoacetic acid
3095-95-2

diethylphosphonoacetic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃;100%
With water; sodium hydroxide In ethanol at 20℃; Inert atmosphere;97%
With hydrogenchloride; potassium hydroxide 1.) aq. EtOH, 20 h;95%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

pivalaldehyde
630-19-3

pivalaldehyde

3-tert-butyl-acrylic acid ethyl ester
87995-20-8

3-tert-butyl-acrylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran Cooling with ice;
Stage #2: pivalaldehyde In tetrahydrofuran at 20℃; for 48h;
Stage #3: With ammonium chloride In tetrahydrofuran; water
100%
(i) NaH, Et2O, (ii) /BRN= 506060/; Multistep reaction;
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 0℃; Inert atmosphere;
Stage #2: pivalaldehyde In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
With sodium tert-pentoxide at 0 - 20℃; for 1h; Horner-Wadsworth-Emmons Olefination; Green chemistry;
With sodium hydride In tetrahydrofuran at 0℃; Inert atmosphere;
furfural
98-01-1

furfural

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

ethyl (E)-3-(2-furyl)prop-2-enoate
623-20-1

ethyl (E)-3-(2-furyl)prop-2-enoate

Conditions
ConditionsYield
With potassium carbonate In neat (no solvent) Mechanism; var. other bases, effect of water;100%
With water; barium dihydroxide In 1,4-dioxane at 70℃; for 0.416667h;100%
With water; barium dihydroxide In 1,4-dioxane at 70℃; for 0.416667h; Product distribution; other catalyst, other solvents, influence of water;100%
3-thiophene carboxaldehyde
498-62-4

3-thiophene carboxaldehyde

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(E)-3-thiophen-3-yl-acrylic acid ethyl ester
50266-60-9

(E)-3-thiophen-3-yl-acrylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 20℃; for 1h;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran; mineral oil at 0 - 20℃; for 3.25h;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With potassium tert-butylate In tetrahydrofuran at 20℃;
Stage #2: 3-thiophene carboxaldehyde In tetrahydrofuran at 90℃; for 0.5h;
90%
Tetrahydro-4H-pyran-4-one
29943-42-8

Tetrahydro-4H-pyran-4-one

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

ethyl tetrahydro-4H-pyran-4-ylideneacetate
130312-00-4

ethyl tetrahydro-4H-pyran-4-ylideneacetate

Conditions
ConditionsYield
With sodium hydride In mineral oil; benzene at 0 - 20℃; for 2.33333h; Inert atmosphere;100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Schlenk technique; Inert atmosphere;
Stage #2: Tetrahydro-4H-pyran-4-one In tetrahydrofuran; mineral oil at 20℃; Schlenk technique; Inert atmosphere;
100%
With potassium carbonate In N,N-dimethyl-formamide at 80℃;96%
cyclohexanedione monoethylene ketal
4746-97-8

cyclohexanedione monoethylene ketal

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

ethyl 1,4-dioxaspiro[4,5]dec-8-ylideneacetate
51656-91-8

ethyl 1,4-dioxaspiro[4,5]dec-8-ylideneacetate

Conditions
ConditionsYield
With sodium hydride In 1,2-dimethoxyethane for 11.5h; Ambient temperature;100%
With sodium hydride In tetrahydrofuran at 0℃; for 0.666667h; Horner-Wadsworth-Emmons reaction;100%
Stage #1: cyclohexanedione monoethylene ketal With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h;
Stage #2: diethoxyphosphoryl-acetic acid ethyl ester In tetrahydrofuran; mineral oil at -20 - 20℃; for 3h;
100%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

ethyl P,P-bis(trimethylsilyl) phosphonoacetate
65868-40-8

ethyl P,P-bis(trimethylsilyl) phosphonoacetate

Conditions
ConditionsYield
at 100℃; for 168h; Inert atmosphere;100%
With potassium iodide In acetonitrile at 25 - 35℃; for 0.5h;
In chlorobenzene at 140℃; for 18h;
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

Octanal
124-13-0

Octanal

ethyl (E)-2-decenate
7367-88-6

ethyl (E)-2-decenate

Conditions
ConditionsYield
With n-butyllithium In 1,2-dimethoxyethane; hexane 1.) 0 deg C, 10 min, 2.) 30 min;100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In diethyl ether at 0℃; for 0.0833333h;
Stage #2: Octanal In diethyl ether for 0.25h;
96%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In diethyl ether; mineral oil at 0℃;
Stage #2: Octanal In diethyl ether; mineral oil at 0℃;
96%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(E)-4,4-Dimethyl-7-(2-oxo-cyclohex-3-enyl)-hept-2-enal

(E)-4,4-Dimethyl-7-(2-oxo-cyclohex-3-enyl)-hept-2-enal

6-(6-ethoxycarbonyl-4,4-dimethylhex-5-enyl)cyclohex-2-enone
91200-48-5

6-(6-ethoxycarbonyl-4,4-dimethylhex-5-enyl)cyclohex-2-enone

Conditions
ConditionsYield
With sodium hydride In 1,2-dimethoxyethane for 1h; Ambient temperature;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(3S,10S,13S)-3-((tert-butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta-[a]phenanthren-17-one
57711-44-1

(3S,10S,13S)-3-((tert-butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta-[a]phenanthren-17-one

(E)-ethyl 3β-(tert-butyldimethylsiloxy)-5α-pregn-17-(20)-en-21-oate
115019-45-9

(E)-ethyl 3β-(tert-butyldimethylsiloxy)-5α-pregn-17-(20)-en-21-oate

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran; ethanol at 85℃; for 15h;100%
With sodium ethanolate In tetrahydrofuran; ethanol for 10h; Heating;98.6%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(E)-4-<(E)-1-methyl-3-(2,6,6-trimethyl-1-cyclohexenyl)-2-propenylidene>-2-cyclohexen-1-one
123718-34-3

(E)-4-<(E)-1-methyl-3-(2,6,6-trimethyl-1-cyclohexenyl)-2-propenylidene>-2-cyclohexen-1-one

ethyl (13E/Z)-10,20-methanoretinoate

ethyl (13E/Z)-10,20-methanoretinoate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 2.5h; Ambient temperature;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazole-3-carboxaldehyde
144148-22-1

7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazole-3-carboxaldehyde

ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate
144148-78-7

ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran Ambient temperature;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(5-Oxo-1-trityloxymethyl-pentyl)-carbamic acid methyl ester

(5-Oxo-1-trityloxymethyl-pentyl)-carbamic acid methyl ester

rac-(E)-ethyl 7-(methoxycarbonyl)amino-8-(trityloxy)-2-octenoate
157330-99-9

rac-(E)-ethyl 7-(methoxycarbonyl)amino-8-(trityloxy)-2-octenoate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 0.5h; Ambient temperature;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

(E)-ethyl 3-(3-nitrophenyl)acrylate
621-19-2

(E)-ethyl 3-(3-nitrophenyl)acrylate

Conditions
ConditionsYield
With water; barium dihydroxide In 1,4-dioxane at 70℃; for 0.416667h;100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester; 3-nitro-benzaldehyde With lithium chloride In acetonitrile at 0℃; for 0.0833333h; Horner-Wadsworth-Emmons reaction;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 0 - 20℃;
96%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: 3-nitro-benzaldehyde In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h;
93%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3,4,5-trimethoxy-benzaldehyde
86-81-7

3,4,5-trimethoxy-benzaldehyde

ethyl (E)-3-(3,4,5-trimethoxyphenyl)acrylate
1878-29-1, 30273-65-5, 31892-98-5

ethyl (E)-3-(3,4,5-trimethoxyphenyl)acrylate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With lithium chloride In tetrahydrofuran at 20℃; for 0.25h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
Stage #2: 3,4,5-trimethoxy-benzaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
100%
With potassium carbonate In water at 70℃; for 4h;90%
With potassium carbonate In water at 70℃; for 4h; Wittig Olefination; stereoselective reaction;90%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

benzaldehyde
100-52-7

benzaldehyde

ethyl cinnamate
4192-77-2

ethyl cinnamate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 1h;100%
With potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene at 20℃; for 2h; Horner-Wadsworth-Emmons reaction; neat (no solvent); optical yield given as %de; stereoselective reaction;100%
With n-butyllithium In tetrahydrofuran; hexane 1.) 0 deg C, 10 min, 2.) 30 min;99%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3-Chlorobenzaldehyde
587-04-2

3-Chlorobenzaldehyde

ethyl (E)-3-(3-chlorophenyl)prop-2-enoate
2373-88-8, 118315-76-7, 62174-98-5

ethyl (E)-3-(3-chlorophenyl)prop-2-enoate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 23℃; for 1h;
Stage #2: m-Chlorobenzaldehyde In tetrahydrofuran for 1h;
100%
With sodium hydride In N,N-dimethyl-formamide at -60℃; Horner-Wadsworth-Emmons Olefination;95%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 30℃; for 4h; Glovebox;84%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

ethyl (E)-3-(3-methoxyphenyl)acrylate
33877-04-2, 24393-55-3

ethyl (E)-3-(3-methoxyphenyl)acrylate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With lithium chloride In tetrahydrofuran at 20℃; for 0.25h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
Stage #2: 3-methoxy-benzaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
100%
With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1h;100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 30℃; for 4h; Glovebox;98%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

isovaleraldehyde
590-86-3

isovaleraldehyde

ethyl (E)-5-methylhex-2-enoate
34993-63-0

ethyl (E)-5-methylhex-2-enoate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In 1,2-dimethoxyethane at 0℃; for 0.416667h;
Stage #2: isovaleraldehyde In 1,2-dimethoxyethane for 16h; Horner-Emmons homologation; Heating;
100%
With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 6h; Wadsworth-Honer-Emmons olefination;95%
With sodium hydride In tetrahydrofuran90%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

2,6-dimethylbenzaldehyde
1123-56-4

2,6-dimethylbenzaldehyde

ethyl (E)-3-(2,6-dimethylphenyl)-2-propenoate
527759-23-5

ethyl (E)-3-(2,6-dimethylphenyl)-2-propenoate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 2,6-dimethylbenzaldehyde In tetrahydrofuran at 20℃; for 6h; Horner-Wadsworth-Emmons reaction;
100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 30℃; for 4h; Glovebox;97%
With potassium tert-butylate Horner-Wadsworth-Emmons olefination;89%
With potassium tert-butylate In tetrahydrofuran Ambient temperature;
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

isobutyraldehyde
78-84-2

isobutyraldehyde

(E)-2-(Diethoxy-phosphoryl)-4-methyl-pent-2-enoic acid ethyl ester
173724-80-6

(E)-2-(Diethoxy-phosphoryl)-4-methyl-pent-2-enoic acid ethyl ester

Conditions
ConditionsYield
With piperidine; acetic acid In benzene for 48h; Heating;100%
With piperidine; acetic acid for 62h; Condensation; Knoevenagel condensation;80%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With triethylamine; titanium tetrachloride In dichloromethane at 0 - 5℃;
Stage #2: isobutyraldehyde In dichloromethane at 0 - 5℃; Horner-Wadsworth-Emmos reaction;
3,4-dibenzyloxybenzaldehyde
5447-02-9

3,4-dibenzyloxybenzaldehyde

diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3-(3,4-bis-benzyloxy-phenyl)-acrylic acid ethyl ester
203571-40-8

3-(3,4-bis-benzyloxy-phenyl)-acrylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran
Stage #2: 3,4-dibenzyloxybenzaldehyde In tetrahydrofuran for 0.166667h; Further stages.;
100%
With sodium hydride In 1,2-dimethoxyethane for 0.333333h;99.5%
With sodium In ethanol Ambient temperature;76%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(S)-3-[2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-thiazol-4-yl]-butyraldehyde
185996-42-3

(S)-3-[2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-thiazol-4-yl]-butyraldehyde

(E)-(S)-5-[2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-thiazol-4-yl]-hex-2-enoic acid ethyl ester
185996-43-4

(E)-(S)-5-[2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethyl)-thiazol-4-yl]-hex-2-enoic acid ethyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride In acetonitrile for 0.25h; Ambient temperature;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde
198336-00-4

(1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde

(E)-4-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-but-2-enoic acid ethyl ester
198336-01-5

(E)-4-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-but-2-enoic acid ethyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 25℃;100%
With sodium hydride 1.) THF, 25 deg C, 30 min, 2.) THF, from 0 to 25 deg C, 5 h; Yield given. Multistep reaction;
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

(1,1-dimethyl-3-oxo-propyl)-carbamic acid tert-butyl ester
181646-38-8

(1,1-dimethyl-3-oxo-propyl)-carbamic acid tert-butyl ester

ethyl (2E)-5-(tert-butoxycarbonylamino)-5-methylhex-2-enoate
181646-40-2

ethyl (2E)-5-(tert-butoxycarbonylamino)-5-methylhex-2-enoate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With potassium tert-butylate In toluene at 60℃; for 0.5h; Wittig-Horner reaction;
Stage #2: (1,1-dimethyl-3-oxo-propyl)-carbamic acid tert-butyl ester In toluene at 60℃; for 0.166667h; Wittig-Horner reaction;
100%
With potassium tert-butylate 1.) THF, RT, 40 min, 2.) THF, RT, 75 min; Yield given. Multistep reaction;
With potassium tert-butylate; sodium hydrogencarbonate In tetrahydrofuran; n-heptane
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