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Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

Chinese Name: Glycyrrhizin English Name: Glabridin CAS No.: 59870-68-7 Molecular formula: C20H20O4 Molecular weight: three hundred and twenty-four point three seven Glabridin is a natural substance with excellent whitening effect, which can only

Glycyrrhizin

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Trading Company

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Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Nanjing Spring & Autumn Biological Engineering Co., Ltd. Which was founded at 2008, has an R & D team composed very experienced natural products chemists. The company is a high-tech enterprise engaged in functional health care products raw ma

100% Pure Natural Licorice Root Extract Powder Cosmetic Grade 40% 98% Glabridin Piowder

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shaanxi HuaTai Bio-fine chemical company Ltd

Glabridin 1. Natural Licorice extract 2. Specification: 10%-98%(HPLC) 3. COA,MSDS offered 4. Prompt shippment Appearance:Reddish brown, white powder Storage:24 months Package: 1kg with double plastic container inside/Aluminum foil bag outside.

Licorice Extract Glabridin

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 30000.0

Type:Trading Company

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price

Glabridin 59870-68-7

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Hangzhou Dingyan Chem Co., Ltd

Items Standard Results Appearance White to off-white powder Conform Assay Glabridin content&

High purity Various Specifications Glabridin CAS:59870-68-7

Cas:59870-68-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Kono Chem Co.,Ltd

Specifications CAS No.: 59870-68-7 Other Names: licorice extract glabridin MF: C20H20O4 Place of Origin: Zhejiang, China (Mainland) Purity:

Licorice Extract Glabridin CAS NO. 59870-68-7

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $100.0 / 200.0

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or off-white powder Storage:cool dry place Package:1kg/foil bag;25kg/drum Application:cosmetic raw material

Manufacturer high quality Glabridin Cas 59870-68-7 with good price

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Company profile Xi’an Quanao Biotech Co., Ltd. with 10 years experience in plant extract filed. Focus on the research, production and sale of Plant and Animal extract, Medical intermediate, complete coverage six industries. Product grade: Med

Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

glabridin

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

SHAANXI FUJIE PHARMACEUTICAL CO.,LTD

Advantage: 1. There is a base of licorice in Uzbekistan 2. More than 20 years of experience in the production of licorice products, began to produce licorice products in 1993 3. Professional international sales team 4. Fast delivery, save time for de

Factory Stock Whitening Gold-Glabridin PT40 in China

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $3100.0 / 3200.0

Type:Trading Company

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Glabridin 59870-68-7 GMP Manufacturer

Cas:59870-68-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

Product Name: Glabridin Powder Application: Comsmetics,Supplement,Food CAS No: 59870-68-7 Appearance: White Powder Purity: 99% Shelf Life: 2 Years Product Highlights: High purity, all-natural, quality rigorously controlled in the factory Appli

Glabridin Powder Cosmetic Grade for Skin Whitening

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Lab/Research institutions

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Glabridin

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Glycyyrrhiza

Cas:59870-68-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Glabridin

Cas:59870-68-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

Licorice Extract Glabridin

Cas:59870-68-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

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Hubei DiBo chemical co., LTD

Name: Glabridin The alias:Light liquorice set CAS NO:59870-68-7 EINECS NO:600-850-8 Molecular formula:C20H20O4 Molecular weight:324.3704 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability

Glabridin/CAS:59870-68-7/ China High quality

Cas:59870-68-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

59870-68-7 Glabridin

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Glabridin 59870-68-7 Natural Licorice Extract Glabridin

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 59870-68-7 with best quality

Cas:59870-68-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Natural Cosmetic Raw Material Glabridin high purity

Cas:59870-68-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: Glabridin CAS No.: 59870-68-7 Molecular Formula: C20H20O4 EINECS: 1308068-626-2 Synonyms: 1,3-Benzenediol,4-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-,(R);Bio-0904;BIDD:ER0172; Appearance: White

Glabridin CAS: 59870-68-7

Cas:59870-68-7

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystalline powder Storage:R.T Package:25kg/drum Application:Face cream, mask, lotion, sunscreen products, etc Transportation:Express/Sea/Air Port:Any port in China

Glabridin cas 59870-68-7 Professional Factory in China

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,3-Benzenediol, 4-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (R)- 59870-68-7

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

High Quality Pure Glabridin/ Jarwhite Gold / Propylene Glycol 100% Safe Customs Clearance

Cas:59870-68-7

Min.Order:10 Gram

FOB Price: $3.5

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Glabridin CAS: 59870-68-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Glabridin CAS: 59870-68-7

Cas:59870-68-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Benzenediol, 4-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (R)-

Cas:59870-68-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail English Name: Glycyrrhizic Flavone Use

wholesale 5%;40%;90%;98%, 99% Glabridin CAS:59870-68-7

Cas:59870-68-7

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

2',4'-dimethylglabridin

2',4'-dimethylglabridin

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
With boron tribromide In dichloromethane at -78 - 20℃; for 2h;84%
With boron tribromide In dichloromethane at -78℃; for 2h; Inert atmosphere;79%
2',4'-di(methoxymethyl)glabridin

2',4'-di(methoxymethyl)glabridin

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol at 20℃; for 5h;
1,3-Dimethoxybenzene
151-10-0

1,3-Dimethoxybenzene

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
2.1: sulfur; morpholine / 12 h / 130 °C
2.2: 12 h / Reflux
3.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
3.2: 0.33 h / 55 °C
3.3: 3 h / 80 °C
4.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
5.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
6.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
2.1: sulfur; morpholine / 12 h / 130 °C
2.2: 12 h / Reflux
3.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
3.2: 0.33 h / 55 °C
3.3: 3 h / 80 °C
4.1: acetic acid; hydrogen; 5%-palladium/activated carbon / ethanol; water / 12 h / 20 °C
5.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
6.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
2.1: sulfur; morpholine / 12 h / 130 °C
2.2: 12 h / Reflux
3.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
3.2: 0.33 h / 55 °C
3.3: 3 h / 80 °C
4.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
5.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
6.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
7.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
2.1: sulfur; morpholine / 12 h / 130 °C
2.2: 12 h / Reflux
3.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
3.2: 0.33 h / 55 °C
3.3: 3 h / 80 °C
4.1: hydrogen / N,N-dimethyl-formamide / 0.5 h / 22 °C / 760.05 Torr
5.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
6.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
7.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
2',4'-dimethoxyacetophenone
829-20-9

2',4'-dimethoxyacetophenone

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sulfur; morpholine / 12 h / 130 °C
1.2: 12 h / Reflux
2.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
2.2: 0.33 h / 55 °C
2.3: 3 h / 80 °C
3.1: acetic acid; hydrogen; 5%-palladium/activated carbon / ethanol; water / 12 h / 20 °C
4.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
5.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 5 steps
1.1: sulfur; morpholine / 12 h / 130 °C
1.2: 12 h / Reflux
2.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
2.2: 0.33 h / 55 °C
2.3: 3 h / 80 °C
3.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
4.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
5.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: sulfur; morpholine / 12 h / 130 °C
1.2: 12 h / Reflux
2.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
2.2: 0.33 h / 55 °C
2.3: 3 h / 80 °C
3.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
4.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
5.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
6.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: sulfur; morpholine / 12 h / 130 °C
1.2: 12 h / Reflux
2.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
2.2: 0.33 h / 55 °C
2.3: 3 h / 80 °C
3.1: hydrogen / N,N-dimethyl-formamide / 0.5 h / 22 °C / 760.05 Torr
4.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
5.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
6.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
recorcinol
108-46-3

recorcinol

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: sodium hydroxide / water / 3 h / 0 - 70 °C
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
3.1: sulfur; morpholine / 12 h / 130 °C
3.2: 12 h / Reflux
4.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
4.2: 0.33 h / 55 °C
4.3: 3 h / 80 °C
5.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
6.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
7.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: sodium hydroxide / water / 3 h / 0 - 70 °C
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
3.1: sulfur; morpholine / 12 h / 130 °C
3.2: 12 h / Reflux
4.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
4.2: 0.33 h / 55 °C
4.3: 3 h / 80 °C
5.1: acetic acid; hydrogen; 5%-palladium/activated carbon / ethanol; water / 12 h / 20 °C
6.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
7.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 8 steps
1.1: sodium hydroxide / water / 3 h / 0 - 70 °C
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
3.1: sulfur; morpholine / 12 h / 130 °C
3.2: 12 h / Reflux
4.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
4.2: 0.33 h / 55 °C
4.3: 3 h / 80 °C
5.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
6.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
7.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
8.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 8 steps
1.1: sodium hydroxide / water / 3 h / 0 - 70 °C
2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C
3.1: sulfur; morpholine / 12 h / 130 °C
3.2: 12 h / Reflux
4.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
4.2: 0.33 h / 55 °C
4.3: 3 h / 80 °C
5.1: hydrogen / N,N-dimethyl-formamide / 0.5 h / 22 °C / 760.05 Torr
6.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
7.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
8.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
2,4-dimethoxyphenylacetic acid
6496-89-5

2,4-dimethoxyphenylacetic acid

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
1.2: 0.33 h / 55 °C
1.3: 3 h / 80 °C
2.1: acetic acid; hydrogen; 5%-palladium/activated carbon / ethanol; water / 12 h / 20 °C
3.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
4.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
1.2: 0.33 h / 55 °C
1.3: 3 h / 80 °C
2.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
3.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
4.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 5 steps
1.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
1.2: 0.33 h / 55 °C
1.3: 3 h / 80 °C
2.1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
3.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
4.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
5.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 5 steps
1.1: boron trifluoride diethyl etherate / 0.17 h / 100 °C
1.2: 0.33 h / 55 °C
1.3: 3 h / 80 °C
2.1: hydrogen / N,N-dimethyl-formamide / 0.5 h / 22 °C / 760.05 Torr
3.1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
4.1: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
5.1: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
3-(2,4-dimethoxyphenyl)-7-hydroxy-4H-chromen-4-one
1891-01-6

3-(2,4-dimethoxyphenyl)-7-hydroxy-4H-chromen-4-one

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid; hydrogen; 5%-palladium/activated carbon / ethanol; water / 12 h / 20 °C
2: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
3: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
2: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
3: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1: acetic acid; hydrogen; platinum on carbon / 12 h / 100 °C
2: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
3: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
4: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1: hydrogen / N,N-dimethyl-formamide / 0.5 h / 22 °C / 760.05 Torr
2: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
3: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
4: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
3-(2,4-dimethoxyphenyl)-chroman-7-ol

3-(2,4-dimethoxyphenyl)-chroman-7-ol

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
2: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
3-(2,4-dimethoxyphenyl)-7-hydroxychroman-4-one
51106-84-4

3-(2,4-dimethoxyphenyl)-7-hydroxychroman-4-one

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid; phenylboronic acid / toluene / 12 h / Reflux; Inert atmosphere
2: lithium aluminium tetrahydride / diethyl ether / 6 h / Reflux
3: boron tribromide / dichloromethane / 2 h / -78 - 20 °C
View Scheme
7-hydroxy-2H-chromen-2-one
93-35-6

7-hydroxy-2H-chromen-2-one

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(II) choride dihydrate / acetonitrile / 10 h / 20 °C
2: bromine / N,N-dimethyl-formamide / 2 h / Cooling with ice
3: 1.5 h / 180 °C
4: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 2 h / 90 °C
5: lithium borohydride / tetrahydrofuran / 20 °C
6: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 10 h / Cooling with ice
7: boron tribromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
View Scheme
7-((2-methylbut-3-yn-2-yl)oxy)-2H-chromen-2-one
27421-18-7

7-((2-methylbut-3-yn-2-yl)oxy)-2H-chromen-2-one

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: bromine / N,N-dimethyl-formamide / 2 h / Cooling with ice
2: 1.5 h / 180 °C
3: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 2 h / 90 °C
4: lithium borohydride / tetrahydrofuran / 20 °C
5: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 10 h / Cooling with ice
6: boron tribromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
View Scheme
C14H11BrO3

C14H11BrO3

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 1.5 h / 180 °C
2: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 2 h / 90 °C
3: lithium borohydride / tetrahydrofuran / 20 °C
4: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 10 h / Cooling with ice
5: boron tribromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
View Scheme
C14H11BrO3

C14H11BrO3

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide; water / 2 h / 90 °C
2: lithium borohydride / tetrahydrofuran / 20 °C
3: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 10 h / Cooling with ice
4: boron tribromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
View Scheme
C22H20O5

C22H20O5

(±)-glabridin
59870-68-7

(±)-glabridin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: lithium borohydride / tetrahydrofuran / 20 °C
2: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / 10 h / Cooling with ice
3: boron tribromide / dichloromethane / 2 h / -78 °C / Inert atmosphere
View Scheme
(±)-glabridin
59870-68-7

(±)-glabridin

1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole
13182-81-5

1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole

C26H27N3O6

C26H27N3O6

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 10h;66%
(±)-glabridin
59870-68-7

(±)-glabridin

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

3-(8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)-2,6-dihydroxybenzaldehyde

3-(8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)-2,6-dihydroxybenzaldehyde

Conditions
ConditionsYield
With trichlorophosphate at 100℃; for 3h; Cooling with ice;
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