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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 11-β,17-α-dihydroxypregn-4-ene-3,20-dione

Cas:641-77-0

Min.Order:1

Negotiable

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 641-77-0 with best quality

Cas:641-77-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE CAS641-77-0

Cas:641-77-0

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We hav

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

11BETA,17ALPHA-DIH1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price;YDROXY-4-PREGNENE-3,20-DIONE Appearance:White Powder Sto

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)- 641-77-0

Cas:641-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE CAS:641-77-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in h

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE CAS:641-77-0

Cas:641-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-

Cas:641-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

OXENOL

Cas:641-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-

Cas:641-77-0

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,6-DICB UNLABELED CERTIFIED STANDARD

Cas:641-77-0

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Huarong Pharm Co., Ltd.

High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

21-Deoxy Cortisol

Cas:641-77-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Trading Company

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE CAS No.641-77-0

Cas:641-77-0

Min.Order:0

Negotiable

Type:Trading Company

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DB BIOTECH CO., LTD

best seller Application:API

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barri

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Cas:641-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione
33767-06-5

11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With 3-mercaptopropionic acid In N,N-dimethyl acetamide for 0.166667h; Ambient temperature;98.9%
With pyridine; iodine; triphenylphosphine In toluene for 6h; Inert atmosphere; Reflux;20%
With acetic acid; zinc
11β,17α-dihydroxy-17-pregn-4-en-20-yn-3-one
137174-13-1

11β,17α-dihydroxy-17-pregn-4-en-20-yn-3-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With mercury(II) sulfate In tetrahydrofuran; methanol at 20℃; for 1.5h;82%
HYDROCORTISONE
50-23-7

HYDROCORTISONE

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With pyridine; iodine; triphenylphosphine In toluene for 6h; Inert atmosphere; Reflux; chemoselective reaction;79%
Multi-step reaction with 2 steps
2: NaI; acetic acid
View Scheme
Multi-step reaction with 2 steps
1: Py
2: NaI, Zn / 1,2-dimethoxy-ethane; H2O / Heating
View Scheme
11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione
33767-06-5

11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione

A

21-deoxycortisol
641-77-0

21-deoxycortisol

B

11β,17α-dihydroxy-21-mercapto-4-pregnene-3,20-dione
61951-99-3

11β,17α-dihydroxy-21-mercapto-4-pregnene-3,20-dione

Conditions
ConditionsYield
With hydrogen sulfide In N,N-dimethyl-formamide at 80℃; for 0.25h;A 61%
B 29.5%
17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
mit Hilfe von Curvularia lunata;
4β-bromo-11β,17-dihydroxy-5β-pregnane-3,20-dione
103795-86-4

4β-bromo-11β,17-dihydroxy-5β-pregnane-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With hydrazine carboxamide nachfolgende Umsetzung mit Brenztraubensaeure;
11β,7α-dihydroxy-21-<(methylsulfonyl)oxy>pregn-4-ene-3,20-dione
6677-96-9

11β,7α-dihydroxy-21-<(methylsulfonyl)oxy>pregn-4-ene-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With acetic acid; sodium iodide
With sodium iodide; zinc In 1,2-dimethoxyethane; water Heating;
3,3-ethanediyldioxy-4β-chloro-11β,17-dihydroxy-5β-pregnan-20-one
114585-39-6

3,3-ethanediyldioxy-4β-chloro-11β,17-dihydroxy-5β-pregnan-20-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With sulfuric acid nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure;
Cortisol 21-tosylate
63644-48-4

Cortisol 21-tosylate

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With hydrogen sulfide; sodium iodide 1.) EtOH, DMF, reflux, 10 min, 2.) EtOH, DMF; Yield given. Multistep reaction;
(8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
382-44-5

(8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / ethylenediamine / toluene / 2 h
2: 32 percent / ethylenediamine / diethyl ether / 2 h
3: 82 percent / HgSO4 / methanol; tetrahydrofuran / 1.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 6 mg / ethylenediamine / toluene / 2 h
2: 82 percent / HgSO4 / methanol; tetrahydrofuran / 1.5 h / 20 °C
View Scheme
11β-hydroxy-17α-ethynyl-17β-hydroxy-4-androsten-3-one
69065-06-1

11β-hydroxy-17α-ethynyl-17β-hydroxy-4-androsten-3-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 32 percent / ethylenediamine / diethyl ether / 2 h
2: 82 percent / HgSO4 / methanol; tetrahydrofuran / 1.5 h / 20 °C
View Scheme
9α-bromo-11β-hydroxy-17α-ethynyl-17β-hydroxy-4-androsten-3-one
139562-74-6

9α-bromo-11β-hydroxy-17α-ethynyl-17β-hydroxy-4-androsten-3-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / α',α'-isobutyronitrile, HBu3Sn / tetrahydrofuran / 3.5 h / Heating
2: 32 percent / ethylenediamine / diethyl ether / 2 h
3: 82 percent / HgSO4 / methanol; tetrahydrofuran / 1.5 h / 20 °C
View Scheme
4β-chloro-17-hydroxy-5β-pregnane-3,11,20-trione
114160-28-0

4β-chloro-17-hydroxy-5β-pregnane-3,11,20-trione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: benzene; toluene-4-sulfonic acid
2: lithium alanate; diethyl ether; benzene
3: acetone; aqueous sulfuric acid
4: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
3α,11α,17-trihydroxy-5β-pregnan-20-one
603-96-3

3α,11α,17-trihydroxy-5β-pregnan-20-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
2: CrO3; pyridine
3: benzene; toluene-4-sulfonic acid
4: lithium alanate; diethyl ether; benzene
5: acetone; aqueous sulfuric acid
6: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
11β,17-dihydroxy-5β-pregnane-3,20-dione
74263-44-8

11β,17-dihydroxy-5β-pregnane-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: DMF; bromine
2: semicarbazide / nachfolgende Umsetzung mit Brenztraubensaeure
View Scheme
3α,17-dihydroxy-5β-pregnane-11,20-dione
641-78-1

3α,17-dihydroxy-5β-pregnane-11,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: tert-butyl hypochlorite; water; tert-butyl alcohol; HCl
2: benzene; toluene-4-sulfonic acid
3: lithium alanate; diethyl ether; benzene
4: acetone; aqueous sulfuric acid
5: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
4β-chloro-11α,17-dihydroxy-5β-pregnane-3,20-dione

4β-chloro-11α,17-dihydroxy-5β-pregnane-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: CrO3; pyridine
2: benzene; toluene-4-sulfonic acid
3: lithium alanate; diethyl ether; benzene
4: acetone; aqueous sulfuric acid
5: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
3,3;20,20-bis-ethanediyldioxy-4β-chloro-5β-pregnane-11β,17-diol
124115-91-9

3,3;20,20-bis-ethanediyldioxy-4β-chloro-5β-pregnane-11β,17-diol

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acetone; aqueous sulfuric acid
2: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
3,3;20,20-bis-ethanediyldioxy-4β-chloro-17-hydroxy-5β-pregnan-11-one
124226-80-8

3,3;20,20-bis-ethanediyldioxy-4β-chloro-17-hydroxy-5β-pregnan-11-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: lithium alanate; diethyl ether; benzene
2: acetone; aqueous sulfuric acid
3: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
20,20-ethanediyldioxy-3α,17-dihydroxy-5β-pregnan-11-one
116105-53-4

20,20-ethanediyldioxy-3α,17-dihydroxy-5β-pregnan-11-one

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: LiAlH4 / folgenden mit wss.HCl
3: CrO3; pyridine
4: benzene; toluene-4-sulfonic acid
5: lithium alanate; diethyl ether; benzene
6: acetone; aqueous sulfuric acid
7: aqueous H2SO4 / nachfolgende Umsetzung mit Semicarbazid und mit Brenztraubensaeure
View Scheme
21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione
75868-48-3

21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: zinc; acetic acid / butanone / 50 - 55 °C
2: water; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; tetrafluoroboric acid / acetone / 3 h / 0 - 5 °C / Inert atmosphere
3: chromium chloride; mercaptoacetic acid; zinc / dimethyl sulfoxide / 2 h / 0 - 5 °C / Inert atmosphere
View Scheme
pregna-4,9(11)-diene-3,20-dione-17-hydroxy-21-methyl
34184-82-2

pregna-4,9(11)-diene-3,20-dione-17-hydroxy-21-methyl

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; tetrafluoroboric acid / acetone / 3 h / 0 - 5 °C / Inert atmosphere
2: chromium chloride; mercaptoacetic acid; zinc / dimethyl sulfoxide / 2 h / 0 - 5 °C / Inert atmosphere
View Scheme
9-bromo-11β,17-dihydroxy-pregn-4-ene-3,20-dione
102445-69-2

9-bromo-11β,17-dihydroxy-pregn-4-ene-3,20-dione

21-deoxycortisol
641-77-0

21-deoxycortisol

Conditions
ConditionsYield
With chromium chloride; mercaptoacetic acid; zinc In dimethyl sulfoxide at 0 - 5℃; for 2h; Solvent; Inert atmosphere;
21-deoxycortisol
641-77-0

21-deoxycortisol

acetic anhydride
108-24-7

acetic anhydride

11β-acetoxy-17α-hydroxy-4-pregnene-3,20-dione
806-46-2

11β-acetoxy-17α-hydroxy-4-pregnene-3,20-dione

Conditions
ConditionsYield
With pyridine; dmap at 20℃; for 6h;100%
With pyridine
21-deoxycortisol
641-77-0

21-deoxycortisol

11β-acetoxy-17α-hydroxy-4-pregnene-3,20-dione
806-46-2

11β-acetoxy-17α-hydroxy-4-pregnene-3,20-dione

Conditions
ConditionsYield
With pyridine; dmap; acetic anhydride In hexane; chloroform100%
21-deoxycortisol
641-77-0

21-deoxycortisol

17-hydroxy-pregn-4-ene-3,11,20-trione
1882-82-2

17-hydroxy-pregn-4-ene-3,11,20-trione

Conditions
ConditionsYield
With Jones reagent In butanone at 0 - 9℃; for 2h; Solvent;98.2%
21-deoxycortisol
641-77-0

21-deoxycortisol

pregna-4,9(11)-diene-3,20-dione-17-hydroxy-21-methyl
34184-82-2

pregna-4,9(11)-diene-3,20-dione-17-hydroxy-21-methyl

Conditions
ConditionsYield
With pyridine; iodine; triphenylphosphine In toluene Inert atmosphere; Reflux; chemoselective reaction;12%
21-deoxycortisol
641-77-0

21-deoxycortisol

(8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-tetradecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-3-one

(8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-tetradecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide In methanol at 0℃; for 3h;
21-deoxycortisol
641-77-0

21-deoxycortisol

9α-Fluoro-17α-hydroxy-6-methyl-4-pregnene-3,20-dione
171611-81-7

9α-Fluoro-17α-hydroxy-6-methyl-4-pregnene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
6: aq. NaOH / methanol / 2 h / 20 °C
7: 23.3 percent / hydrogen fluoride; pyridine / 60 h / -15 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

6-methyl-4-pregnene-11β,17α-diol-3,20-dione
111819-45-5

6-methyl-4-pregnene-11β,17α-diol-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
6: aq. NaOH / methanol / 2 h / 20 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

(8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-5,11,17-trihydroxy-6,10,13-trimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one
171865-12-6

(8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-5,11,17-trihydroxy-6,10,13-trimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

C26H39FO5
171611-82-8

C26H39FO5

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
6: aq. NaOH / methanol / 2 h / 20 °C
7: 23.3 percent / hydrogen fluoride; pyridine / 60 h / -15 °C
8: p-TsOH / benzene / 3 h / Heating
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

C26H42O7
171754-63-5

C26H42O7

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

C27H40O8
171611-80-6

C27H40O8

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

17α-acetoxy-9α-fluoro-6α-methylprogesterone

17α-acetoxy-9α-fluoro-6α-methylprogesterone

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
6: aq. NaOH / methanol / 2 h / 20 °C
7: 23.3 percent / hydrogen fluoride; pyridine / 60 h / -15 °C
8: p-TsOH / benzene / 3 h / Heating
9: 23 mg / aq. KHSO4 / acetone / 2 h / 70 °C
10: 36 percent / p-TsOH / CH2Cl2 / 5 h / -10 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

C27H40O7
187244-71-9

C27H40O7

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: pyridine
2: p-TSA
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

9α-fluoro-17α-hydroxy-6α-methyl-4-pregnene-3,20-dione
171754-64-6

9α-fluoro-17α-hydroxy-6α-methyl-4-pregnene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 100 percent / 4-dimethylaminopyridine; pyridine / 6 h / 20 °C
2: p-TsOH / benzene / 7 h / Heating
3: m-chloroperbenzoic acid / CHCl3 / 12 h / 20 °C
4: tetrahydrofuran / 18 h / Heating
5: aq. KHSO4 / acetone / 2 h / 70 °C
6: aq. NaOH / methanol / 2 h / 20 °C
7: 23.3 percent / hydrogen fluoride; pyridine / 60 h / -15 °C
8: p-TsOH / benzene / 3 h / Heating
9: 23 mg / aq. KHSO4 / acetone / 2 h / 70 °C
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

4-(carboxymethylthio)-21-deoxycortisol
81983-33-7

4-(carboxymethylthio)-21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 30percent H2O2, 10percent NaOH / methanol / 3 h / 0 °C
2: 25percent KOH / ethanol; dioxane / 2 h / Ambient temperature
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

4-(2-carboxyethylthio)-21-deoxycortisol
81983-34-8

4-(2-carboxyethylthio)-21-deoxycortisol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 30percent H2O2, 10percent NaOH / methanol / 3 h / 0 °C
2: 25percent KOH / ethanol; dioxane / 2 h / Ambient temperature
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

((8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-4-ylsulfanyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester
81983-49-5

((8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-4-ylsulfanyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 30percent H2O2, 10percent NaOH / methanol / 3 h / 0 °C
2: 25percent KOH / ethanol; dioxane / 2 h / Ambient temperature
3: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide*HCl / dioxane; H2O / 2 h / Ambient temperature
View Scheme
21-deoxycortisol
641-77-0

21-deoxycortisol

3-((8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-4-ylsulfanyl)-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester
81983-50-8

3-((8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-4-ylsulfanyl)-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 30percent H2O2, 10percent NaOH / methanol / 3 h / 0 °C
2: 25percent KOH / ethanol; dioxane / 2 h / Ambient temperature
3: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide*HCl / dioxane; H2O / 2 h / Ambient temperature
View Scheme

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