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Suzhou Sibian Chemical Technology Co., Ltd

Lower price, sample is available,large stock in warehouse.Best service, high quality and reasonable price.If you are looking for the material's manufacturer or supplier in China, Sibian chemical is your best choice. Application:Drug R&D

4-Methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Methyloxazole

Cas:693-93-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Oxazole, 4-methyl- 693-93-6 ISO Manufacturer

Cas:693-93-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Methyloxazole

Cas:693-93-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

4-Methyloxazole CAS 693-93-6

Cas:693-93-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 693-93-6 with competitive price

Cas:693-93-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

4-methyloxazole CAS:693-93-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedia

4-methyloxazole CAS:693-93-6

Cas:693-93-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Methyloxazole

Cas:693-93-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-methyl-1,3-oxazole

Cas:693-93-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-Methyl-oxazole CAS NO.693-93-6

Cas:693-93-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Top Purity 4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-methyloxazole

Cas:693-93-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-methyloxazole

Cas:693-93-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-methyloxazole

Cas:693-93-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ 4-Methyloxazole /Manufacturer in China

Cas:693-93-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-methyloxazole

Cas:693-93-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

4-Methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

4-Methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

Oxazole, 4-methyl-

Cas:693-93-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:intermediate

4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

4-methyloxazole

Cas:693-93-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-methyl-1,3-oxazole-5-carboxylic acid
2510-32-9

4-methyl-1,3-oxazole-5-carboxylic acid

4-methyloxazole
693-93-6

4-methyloxazole

Conditions
ConditionsYield
With copper(II) oxide at 180℃;75%
With copper(II) oxide
rac-octan-2-ol
4128-31-8

rac-octan-2-ol

hydroxy-2-propanone
116-09-6

hydroxy-2-propanone

4-methyloxazole
693-93-6

4-methyloxazole

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; hydrogen isocyanide In N,N-dimethyl-aniline; 1,2-dichloro-benzene
hydroxy-2-propanone
116-09-6

hydroxy-2-propanone

4-methyloxazole
693-93-6

4-methyloxazole

Conditions
ConditionsYield
With N,N-diethylaniline
With hydrogenchloride; hydrogen isocyanide In N,N-dimethyl-aniline; nitrobenzene; cyclohexanol
2-Methylcyclohexanol
583-59-5

2-Methylcyclohexanol

hydroxy-2-propanone
116-09-6

hydroxy-2-propanone

4-methyloxazole
693-93-6

4-methyloxazole

Conditions
ConditionsYield
With hydrogenchloride; hydrogen isocyanide In dichloromethane; N,N-dimethyl-aniline
formimido-cyclohexyl ester hydrochloride

formimido-cyclohexyl ester hydrochloride

hydroxy-2-propanone
116-09-6

hydroxy-2-propanone

4-methyloxazole
693-93-6

4-methyloxazole

Conditions
ConditionsYield
With N,N-diethylaniline
With 1-methyl-pyrrolidin-2-one; N,N-diethylaniline
formimido-cyclohexyl ester

formimido-cyclohexyl ester

hydroxy-2-propanone
116-09-6

hydroxy-2-propanone

4-methyloxazole
693-93-6

4-methyloxazole

4-methyloxazole
693-93-6

4-methyloxazole

4-methylphenyl methylsulfide
623-13-2

4-methylphenyl methylsulfide

4-methyl-2-(p-tolyl)oxazole
83081-31-6

4-methyl-2-(p-tolyl)oxazole

Conditions
ConditionsYield
With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl) palladium(II) dichloride; 2,2,6,6-tetramethylpiperidyl zinc chloride-lithium chloride complex In tetrahydrofuran at 80℃; for 6h; Inert atmosphere; regioselective reaction;98%
4-methyloxazole
693-93-6

4-methyloxazole

triisopropylsilyl trifluoromethanesulfonate
80522-42-5

triisopropylsilyl trifluoromethanesulfonate

4-methyl-2-(triisopropylsilyl)oxazole

4-methyl-2-(triisopropylsilyl)oxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -30℃; for 0.5h;
Stage #2: triisopropylsilyl trifluoromethanesulfonate In tetrahydrofuran; hexane at -10℃;
98%
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: triisopropylsilyl trifluoromethanesulfonate In tetrahydrofuran at -10 - 25℃; for 12h; Inert atmosphere;
81%
4-methyloxazole
693-93-6

4-methyloxazole

C14H15BrN6O4

C14H15BrN6O4

C18H19N7O5
1340588-62-6

C18H19N7O5

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: C14H15BrN6O4 With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 75℃; for 0.166667h; Negishi coupling reaction; Inert atmosphere; Microwave irradiation;
88%
4-methyloxazole
693-93-6

4-methyloxazole

3-<1-(Methoxycarbonyl)cyclopropyl>-2-propinsaeure-methylester
104462-87-5

3-<1-(Methoxycarbonyl)cyclopropyl>-2-propinsaeure-methylester

4-<1-(Methoxycarbonyl)cyclopropyl>-3-furancarbonsaeure-methylester
104462-98-8

4-<1-(Methoxycarbonyl)cyclopropyl>-3-furancarbonsaeure-methylester

Conditions
ConditionsYield
at 220℃; for 20h;87%
4-methyloxazole
693-93-6

4-methyloxazole

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

(Z)-2-isocyano-O-(trimethylsilyl)-1-propen-1-ol
90892-92-5

(Z)-2-isocyano-O-(trimethylsilyl)-1-propen-1-ol

Conditions
ConditionsYield
With n-butyllithium In diethyl ether at -78℃;85%
With n-butyllithium 1.) hexane, Et2O, 1 h; Yield given. Multistep reaction;
4-methyloxazole
693-93-6

4-methyloxazole

(2-amino-6-bromo-3-nitropyridin-4-yl)-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester
947145-09-7

(2-amino-6-bromo-3-nitropyridin-4-yl)-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester

[2-amino-6-(4-methyloxazol-2-yl)-3-nitropyridin-4-yl]-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester
947143-92-2

[2-amino-6-(4-methyloxazol-2-yl)-3-nitropyridin-4-yl]-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: (2-amino-6-bromo-3-nitropyridin-4-yl)-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 60℃; for 0.25h; Negishi coupling reaction; Inert atmosphere; Microwave irradiation;
85%
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h; Cooling with acetone-dry ice;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78 - 20℃; for 0.25h;
Stage #3: (2-amino-6-bromo-3-nitropyridin-4-yl)-(6-methylpyridin-3-ylmethyl)carbamic acid ethyl ester; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 60℃; for 0.25h; Microwave irradiation;
4-methyloxazole
693-93-6

4-methyloxazole

methyl 3-<1'-chlorocyclopropyl>propiolate
83662-44-6

methyl 3-<1'-chlorocyclopropyl>propiolate

A

4-(1-Chlorcyclopropyl)-3-furancarbonsaeure-methylester
104462-97-7

4-(1-Chlorcyclopropyl)-3-furancarbonsaeure-methylester

B

acetonitrile
75-05-8

acetonitrile

Conditions
ConditionsYield
at 140℃;A 80%
B n/a
4-methyloxazole
693-93-6

4-methyloxazole

acetyl chloride
75-36-5

acetyl chloride

(Z)-2-isocyano-O-acetyl-1-propen-1-ol
90892-91-4

(Z)-2-isocyano-O-acetyl-1-propen-1-ol

Conditions
ConditionsYield
With n-butyllithium In diethyl ether at -78℃;80%
With n-butyllithium 1.) hexane, Et2O, 1 h; Yield given. Multistep reaction;
4-methyloxazole
693-93-6

4-methyloxazole

C15H16BrN5O5

C15H16BrN5O5

C19H20N6O6
1340588-61-5

C19H20N6O6

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: C15H16BrN5O5 With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 90℃; for 0.0833333h; Negishi coupling reaction; Inert atmosphere; Microwave irradiation;
80%
4-methyloxazole
693-93-6

4-methyloxazole

C14H15BrN6O4

C14H15BrN6O4

C18H19N7O5
1340588-60-4

C18H19N7O5

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: C14H15BrN6O4 With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 65℃; for 1h; Negishi coupling reaction; Inert atmosphere;
75%
4-methyloxazole
693-93-6

4-methyloxazole

4-bromo-2-methylpyridine
22282-99-1

4-bromo-2-methylpyridine

4-methyl-2-(2-methylpyridin-4-yl)oxazole

4-methyl-2-(2-methylpyridin-4-yl)oxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium; zinc(II) chloride In tetrahydrofuran; 2-methyltetrahydrofuran at -78 - 22℃; for 0.5h;
Stage #2: 4-bromo-2-methylpyridine With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; 2-methyltetrahydrofuran at 60℃; for 2h;
70%
4-methyloxazole
693-93-6

4-methyloxazole

3,3,3-trifluoroprop-1-yne
661-54-1

3,3,3-trifluoroprop-1-yne

A

3-trifluoromethyl furan
56286-84-1

3-trifluoromethyl furan

B

acetonitrile
75-05-8

acetonitrile

Conditions
ConditionsYield
In toluene at 180 - 190℃; for 13h;A 67%
B 6%
4-methyloxazole
693-93-6

4-methyloxazole

(2-amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester
947145-74-6

(2-amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester

[2-amino-6-(4-methyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(3-cyano-benzyl)-carbamic acid ethyl ester
947145-82-6

[2-amino-6-(4-methyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(3-cyano-benzyl)-carbamic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 60℃; for 0.25h; Negishi coupling reaction; Inert atmosphere; Microwave irradiation;
65%
4-methyloxazole
693-93-6

4-methyloxazole

tributyltin chloride
1461-22-9

tributyltin chloride

4-methyl-2-(tributylstannyl)oxazole

4-methyl-2-(tributylstannyl)oxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; diethyl ether at -78℃; for 1h;
Stage #2: tributyltin chloride In tetrahydrofuran; diethyl ether at -78℃; for 1h;
61%
Stage #1: 4-methyloxazole In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: tributyltin chloride In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;
4-methyloxazole
693-93-6

4-methyloxazole

2-bromo-4-methyloxazole

2-bromo-4-methyloxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.666667h;
Stage #2: With 1,2-dibromo-1,1,2,2-tetrafluoroethane In tetrahydrofuran; hexane at -78 - 25℃; regioselective reaction;
61%
4-methyloxazole
693-93-6

4-methyloxazole

5-bromo-2-methylpyridine
3430-13-5

5-bromo-2-methylpyridine

4-methyl-2-(6-methylpyridin-3-yl)oxazole

4-methyl-2-(6-methylpyridin-3-yl)oxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium; zinc(II) chloride In tetrahydrofuran; 2-methyltetrahydrofuran at -78 - 22℃; for 0.5h;
Stage #2: 5-bromo-2-methylpyridine With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; 2-methyltetrahydrofuran at 60℃; for 2h;
53%
4-methyloxazole
693-93-6

4-methyloxazole

5-bromo-2-(cyanomethyl)benzonitrile
925672-89-5

5-bromo-2-(cyanomethyl)benzonitrile

2-(cyanomethyl)-5-(4-methyl-1,3-oxazol-5-yl)benzonitrile

2-(cyanomethyl)-5-(4-methyl-1,3-oxazol-5-yl)benzonitrile

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl-formamide at 90℃; for 3h; Inert atmosphere;50%
4-methyloxazole
693-93-6

4-methyloxazole

3-Cyclopropyl-2-propinsaeure-methylester
80866-48-4

3-Cyclopropyl-2-propinsaeure-methylester

4-Cyclopropyl-3-furancarbonsaeure-methylester
104462-89-7

4-Cyclopropyl-3-furancarbonsaeure-methylester

Conditions
ConditionsYield
In toluene at 220 - 230℃; for 16h;45%
4-methyloxazole
693-93-6

4-methyloxazole

methyl 2-bromoisonicotinate
26156-48-9

methyl 2-bromoisonicotinate

methyl 2-(4-methyloxazol-2-yl)isonicotinate

methyl 2-(4-methyloxazol-2-yl)isonicotinate

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran at -78 - 20℃;
Stage #3: methyl 2-bromoisonicotinate With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 60℃; for 0.5h; Inert atmosphere; Microwave irradiation;
45%
4-methyloxazole
693-93-6

4-methyloxazole

(2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester
947145-70-2

(2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester

[2-amino-6-(4-methyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester
947145-78-0

[2-amino-6-(4-methyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane at -78℃; for 0.25h;
Stage #3: (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-trifluoromethyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; hexane at 90℃; for 0.0833333h; Negishi coupling reaction; Inert atmosphere; Microwave irradiation;
44%
4-methyloxazole
693-93-6

4-methyloxazole

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

4-methyl-5-oxazolecarboxaldehyde

4-methyl-5-oxazolecarboxaldehyde

Conditions
ConditionsYield
With n-butyllithium In diethyl ether; hexane at -70 - 20℃; for 2h; Inert atmosphere;40%
With n-butyllithium 1.) THF, -75 deg C, 45 min, 2.) THF, from -75 deg C to RT; Yield given. Multistep reaction;
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran at -78℃; for 0.75h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at 20℃;
4-methyloxazole
693-93-6

4-methyloxazole

8-(1-ethyl-propyl)-3-iodo-2,6-dimethyl-imidazo[1,2-b]pyridazine
910552-65-7

8-(1-ethyl-propyl)-3-iodo-2,6-dimethyl-imidazo[1,2-b]pyridazine

8-(1-ethyl-propyl)-2,6-dimethyl-3-(4-methyl-oxazol-5-yl)-imidazo[1,2-b]pyridazine

8-(1-ethyl-propyl)-2,6-dimethyl-3-(4-methyl-oxazol-5-yl)-imidazo[1,2-b]pyridazine

Conditions
ConditionsYield
With caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0); triphenylphosphine In N,N-dimethyl-formamide at 130℃;39%
4-methyloxazole
693-93-6

4-methyloxazole

methyl 3-<1'-chlorocyclopropyl>propiolate
83662-44-6

methyl 3-<1'-chlorocyclopropyl>propiolate

4-(1-Chlorcyclopropyl)-3-furancarbonsaeure-methylester
104462-97-7

4-(1-Chlorcyclopropyl)-3-furancarbonsaeure-methylester

Conditions
ConditionsYield
In toluene at 150℃; for 18h;30%
4-methyloxazole
693-93-6

4-methyloxazole

benzaldehyde
100-52-7

benzaldehyde

(4-Methyl-oxazol-2-yl)-phenyl-methanol
90892-90-3

(4-Methyl-oxazol-2-yl)-phenyl-methanol

Conditions
ConditionsYield
With n-butyllithium In diethyl ether at -78℃;30%
With n-butyllithium 1.) hexane, Et2O, 1 h; Yield given. Multistep reaction;
4-methyloxazole
693-93-6

4-methyloxazole

4,7-dihydro-2-(4,7-dihydro-1,3-dioxepin-2-yl)-5-nitro-1,3-dioxepin

4,7-dihydro-2-(4,7-dihydro-1,3-dioxepin-2-yl)-5-nitro-1,3-dioxepin

1,5-dihydro-3-(4,7-dihydro-1,3-dioxepin-2-yl)-9-hydroxy-8-methyl-3H-<1,3>dioxepino<5,6-c>pyridine
187467-53-4

1,5-dihydro-3-(4,7-dihydro-1,3-dioxepin-2-yl)-9-hydroxy-8-methyl-3H-<1,3>dioxepino<5,6-c>pyridine

Conditions
ConditionsYield
With perchloric acid for 4h; Heating;27.7%
4-methyloxazole
693-93-6

4-methyloxazole

4,7-dihydro-2-<3-(4,7-dihydro-1,3-dioxepin-2-yl)-propyl>-1,3-dioxepin
10192-66-2

4,7-dihydro-2-<3-(4,7-dihydro-1,3-dioxepin-2-yl)-propyl>-1,3-dioxepin

A

7-[3-(4,7-Dihydro-[1,3]dioxepin-2-yl)-propyl]-3-methyl-5,9-dihydro-6,8-dioxa-2-aza-benzocyclohepten-4-ol
187467-61-4

7-[3-(4,7-Dihydro-[1,3]dioxepin-2-yl)-propyl]-3-methyl-5,9-dihydro-6,8-dioxa-2-aza-benzocyclohepten-4-ol

B

3-[3-(1,5-dihydro-9-hydroxy-8-methyl-3H-[1,3]dioxepino[5,6-c]pyridin-3-yl)-propyl]-1,5-dihydro-9-hydroxy-8-methyl-3H-[1,3]dioxepino[5,6-c]pyridine

3-[3-(1,5-dihydro-9-hydroxy-8-methyl-3H-[1,3]dioxepino[5,6-c]pyridin-3-yl)-propyl]-1,5-dihydro-9-hydroxy-8-methyl-3H-[1,3]dioxepino[5,6-c]pyridine

Conditions
ConditionsYield
With acetic anhydride; nitrobenzene; hydroquinone at 180 - 190℃; for 2h;A 23.6%
B 11.9%
4-methyloxazole
693-93-6

4-methyloxazole

6-chloro-4-iodo-1-(phenylsulfonyl)-1H-indazole
1254036-94-6

6-chloro-4-iodo-1-(phenylsulfonyl)-1H-indazole

2-(6-chloro-1-(phenylsulfonyl)-1H-indazol-4-yl)-4-methyloxazole

2-(6-chloro-1-(phenylsulfonyl)-1H-indazol-4-yl)-4-methyloxazole

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -70℃; for 0.5h;
Stage #2: 6-chloro-4-iodo-1-(phenylsulfonyl)-1H-indazole With tetrakis(triphenylphosphine) palladium(0); zinc(II) chloride In tetrahydrofuran; hexane at 0℃; for 7h; Reflux;
22%
4-methyloxazole
693-93-6

4-methyloxazole

2-bromopentan-3-one
815-52-1

2-bromopentan-3-one

A

2-(2,2,3,3-Tetrafluorpropoxy)-3-pentanon
109308-43-2

2-(2,2,3,3-Tetrafluorpropoxy)-3-pentanon

endo-2,endo-4,7-Trimethyl-8-oxa-6-azabicyclo<3.2.1>oct-6-en-3-on
109308-56-7

endo-2,endo-4,7-Trimethyl-8-oxa-6-azabicyclo<3.2.1>oct-6-en-3-on

Conditions
ConditionsYield
With 2,2,3,3-tetrafluoropropanol; sodium 2,2,3,3-tetrafluoropropan-1-olate for 19h;A 12%
B 13%
4-methyloxazole
693-93-6

4-methyloxazole

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

methyl 4-methyloxazole-2-carboxylate
1429559-59-0

methyl 4-methyloxazole-2-carboxylate

Conditions
ConditionsYield
Stage #1: 4-methyloxazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: chloroformic acid ethyl ester In tetrahydrofuran; hexane at -78 - 20℃;
13%

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