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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,4,6-Trifluoropyrimidine

Cas:696-82-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2,4,6-TRIFLUOROPYRIMIDINE 696-82-2

Cas:696-82-2

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 696-82-2 with best quality

Cas:696-82-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:10 Kilogram

FOB Price: $30.0 / 40.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyrimidine,2,4,6-trifluoro- 696-82-2

Cas:696-82-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2,4,6-TRIFLUOROPYRIMIDINE CAS:696-82-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2,4,6-TRIFLUOROPYRIMIDINE CAS:696-82-2

Cas:696-82-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyrimidine,2,4,6-trifluoro-

Cas:696-82-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyrimidine,2,4,6-trifluoro-

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used to make other chem

2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,4,6-Trifluoropyrimidine

Cas:696-82-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pyrimidine,2,4,6-trifluoro-

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,4,6-trifluoropyrimidine manufacturer

Cas:696-82-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,4,6-Trifluoropyrimidine

Cas:696-82-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Greenutra Resource Inc

2,4,6-trifluoropyrimidineAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2,4,6-trifluoropyrimidine

Cas:696-82-2

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,3'-Bipyridine

Cas:696-82-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Pyrimidine,2,4,6-trifluoro-

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pyrimidine,2,4,6-trifluoro-

Cas:696-82-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

2,4,6-TRIFLUOROPYRIMIDINE Application:2,4,6-TRIFLUOROPYRIMIDINE

2,4,6-TRIFLUOROPYRIMIDINE

Cas:696-82-2

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2,4,6-trichloropyrimidine
3764-01-0

2,4,6-trichloropyrimidine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

Conditions
ConditionsYield
With 1,8-bis(dimethylamino)naphthalene (hydrogen fluoride) In acetonitrile Ambient temperature;79%
With potassium fluoride; 18-crown-6 ether In sulfolane at 150℃; for 3.5h;56%
With tetrabutyl phosphonium hydrogen difluoride at 50℃; for 4h;85 % Chromat.
2,4,6-trichloropyrimidine
3764-01-0

2,4,6-trichloropyrimidine

A

2,4-dichloro-6-fluoropyrimidine
3833-57-6

2,4-dichloro-6-fluoropyrimidine

B

2-fluoro-4,6-dichloropyrimidine
3824-45-1

2-fluoro-4,6-dichloropyrimidine

C

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

Conditions
ConditionsYield
With potassium fluoride at 300℃; for 2h; Product distribution; C4HCl3N2/KF = 4 x 10 E-2, other times, other temperatures, other molar ratios, other fluorinated products;A n/a
B n/a
C 37%
morpholine
110-91-8

morpholine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

2,4-bis(morpholino)-6-fluoropyrimidine

2,4-bis(morpholino)-6-fluoropyrimidine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;95%
2-methylpropylmagnesium chloride
5674-02-2

2-methylpropylmagnesium chloride

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

2,4-difluoro-6-(2-methylpropyl)pyrimidine
1246034-33-2

2,4-difluoro-6-(2-methylpropyl)pyrimidine

Conditions
ConditionsYield
iron(III)-acetylacetonate In tetrahydrofuran at -75 - -65℃; for 1.75h; Inert atmosphere;94%
piperidine
110-89-4

piperidine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

4-Fluoro-2,6-di-piperidin-1-yl-pyrimidine

4-Fluoro-2,6-di-piperidin-1-yl-pyrimidine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;90%
hexamethylene imine
111-49-9

hexamethylene imine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

2,4-bis(azepan-1-yl)-6-fluoropyrimidine

2,4-bis(azepan-1-yl)-6-fluoropyrimidine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;90%
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

benzylamine
100-46-9

benzylamine

N2,N4-Dibenzyl-6-fluoro-pyrimidine-2,4-diamine

N2,N4-Dibenzyl-6-fluoro-pyrimidine-2,4-diamine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;90%
ethylamine
75-04-7

ethylamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

N2,N4-Diethyl-6-fluoro-pyrimidine-2,4-diamine

N2,N4-Diethyl-6-fluoro-pyrimidine-2,4-diamine

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 50 - 60℃; for 1h;90%
phenylglyoxylic acid ethyl ester
1603-79-8

phenylglyoxylic acid ethyl ester

tert-butyldimethylsilyloxydiethyl phosphonic ester
120341-31-3

tert-butyldimethylsilyloxydiethyl phosphonic ester

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

ethyl 2-(diethoxyphosphoryloxy)-2-(2,6-difluoropyrimidin-4-yl)-2-phenylacetate

ethyl 2-(diethoxyphosphoryloxy)-2-(2,6-difluoropyrimidin-4-yl)-2-phenylacetate

Conditions
ConditionsYield
With 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ5,4Λ5-catenadi(phosphazene) In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 4h; Inert atmosphere;90%
dibutylamine
111-92-2

dibutylamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

N2,N2,N4,N4-Tetrabutyl-6-fluoro-pyrimidine-2,4-diamine

N2,N2,N4,N4-Tetrabutyl-6-fluoro-pyrimidine-2,4-diamine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;85%
N-butylamine
109-73-9

N-butylamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

N2,N4-Dibutyl-6-fluoro-pyrimidine-2,4-diamine

N2,N4-Dibutyl-6-fluoro-pyrimidine-2,4-diamine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;85%
piperazine
110-85-0

piperazine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

4-Fluoro-2,6-di-piperazin-1-yl-pyrimidine

4-Fluoro-2,6-di-piperazin-1-yl-pyrimidine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50 - 60℃; for 1h;80%
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

benzylmagnesium chloride
6921-34-2

benzylmagnesium chloride

2,4-difluoro-6-(phenylmethyl)pyrimidine
1246033-77-1

2,4-difluoro-6-(phenylmethyl)pyrimidine

Conditions
ConditionsYield
In tetrahydrofuran at -75 - -65℃; for 1.5h; Inert atmosphere;79%
guanidine hydrochloride
50-01-1

guanidine hydrochloride

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

2-guanidino-4,6-difluoropyrimidine

2-guanidino-4,6-difluoropyrimidine

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 10℃;76%
4-[4-((S)-1-aminoethyl)benzyl]piperazine-1-carboxylic acid tert-butyl ester

4-[4-((S)-1-aminoethyl)benzyl]piperazine-1-carboxylic acid tert-butyl ester

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

tert-butyl (S)-4-(4-(1-((4,6-difluoropyrimidin-2-yl)amino)ethyl)benzyl)piperazine-1-carboxylate

tert-butyl (S)-4-(4-(1-((4,6-difluoropyrimidin-2-yl)amino)ethyl)benzyl)piperazine-1-carboxylate

Conditions
ConditionsYield
In diethyl ether at -20 - 20℃;74%
tert-butyl 4-[1-[4-[(1S)-1-aminoethyl]phenyl]-2-cyclopropylethyl]piperazine-1-carboxylate

tert-butyl 4-[1-[4-[(1S)-1-aminoethyl]phenyl]-2-cyclopropylethyl]piperazine-1-carboxylate

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

tert-butyl 4-(2-cyclopropyl-1-(4-((S)-1-((4,6-difluoropyrimidin-2-yl)amino)ethyl)phenyl)ethyl)piperazine-1-carboxylate

tert-butyl 4-(2-cyclopropyl-1-(4-((S)-1-((4,6-difluoropyrimidin-2-yl)amino)ethyl)phenyl)ethyl)piperazine-1-carboxylate

Conditions
ConditionsYield
In diethyl ether at -40 - 20℃;74%
bis(1,5-cyclooctadiene)nickel (0)
1295-35-8

bis(1,5-cyclooctadiene)nickel (0)

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

triethylphosphine
554-70-1

triethylphosphine

[NiF(P(C2H5)3)2(C4HN2F2)]
256234-36-3

[NiF(P(C2H5)3)2(C4HN2F2)]

Conditions
ConditionsYield
In hexane addn. of PEt3 to the Ni complex in hexane, stirring (room temp., 5 min),addn. of the pyrimidine, stirring (10 min); removal of volatiles (vac.), dissoln. (hexane), filtration, concn., crystn. on cooling tp -20°C overnight;72%
1-Adamantanamine
768-94-5

1-Adamantanamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

Adamantan-1-yl-(2,6-difluoro-pyrimidin-4-yl)-amine

Adamantan-1-yl-(2,6-difluoro-pyrimidin-4-yl)-amine

B

Adamantan-1-yl-(4,6-difluoro-pyrimidin-2-yl)-amine

Adamantan-1-yl-(4,6-difluoro-pyrimidin-2-yl)-amine

Conditions
ConditionsYield
With sodium carbonate In water at 0 - 10℃; for 1h; Yields of byproduct given;A n/a
B 70%
With sodium carbonate In water at 0 - 10℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
ethylamine
75-04-7

ethylamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

2-ethylamino-4,6-difluoropyrimidine
165258-59-3

2-ethylamino-4,6-difluoropyrimidine

B

4-ethylamino-2,6-difluoropyrimidine

4-ethylamino-2,6-difluoropyrimidine

Conditions
ConditionsYield
In water at 0 - 10℃; for 1h;A 70%
B 30%
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

4-amino-2,6-difluoropyrimidine
675-12-7

4-amino-2,6-difluoropyrimidine

B

2-amino-4,6-difluoropyrimidine
675-11-6

2-amino-4,6-difluoropyrimidine

C

2,4-diamino-6-fluoropyrimidine
696-83-3

2,4-diamino-6-fluoropyrimidine

Conditions
ConditionsYield
With ammonia In methanol at 20℃;A n/a
B n/a
C 67%
[Ni(FHF)(P(C2H5)3)2(C4HN2F2)]

[Ni(FHF)(P(C2H5)3)2(C4HN2F2)]

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

[Ni(P(C2H5)3)2(C4HN2F2)(C4HN2F2O)]
256234-43-2

[Ni(P(C2H5)3)2(C4HN2F2)(C4HN2F2O)]

Conditions
ConditionsYield
With CsOH*H2O In tetrahydrofuran stirring (room temp., 20 h); removal of volatiles (vac.), extn. (hexane), filtration, pptn. on concn.in vacuo;67%
piperidine
110-89-4

piperidine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

4,6-Difluoro-2-piperidin-1-yl-pyrimidine

4,6-Difluoro-2-piperidin-1-yl-pyrimidine

B

2,4-Difluoro-6-piperidin-1-yl-pyrimidine

2,4-Difluoro-6-piperidin-1-yl-pyrimidine

Conditions
ConditionsYield
In water at 0 - 10℃; for 1h; Yields of byproduct given;A 65%
B n/a
In water at 0 - 10℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

benzylamine
100-46-9

benzylamine

A

2-benzylamino-4,6-difluoropyrimidine
130866-84-1

2-benzylamino-4,6-difluoropyrimidine

B

4-benzylamino-2,6-difluoropyrimidine

4-benzylamino-2,6-difluoropyrimidine

Conditions
ConditionsYield
In water at 0 - 10℃; for 1h; Yields of byproduct given;A 65%
B n/a
In water at 0 - 10℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
ethanolamine
141-43-5

ethanolamine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

4,6-difluoro-(2-hydroxyethylamino)pyrimidine

4,6-difluoro-(2-hydroxyethylamino)pyrimidine

B

2-(2,6-difluoro-pyrimidin-4-ylamino)-ethanol

2-(2,6-difluoro-pyrimidin-4-ylamino)-ethanol

Conditions
ConditionsYield
In ethanol at 20℃;A 65%
B n/a
helium

helium

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

2,4,5,6-tetrafluoropyrimidine
767-79-3

2,4,5,6-tetrafluoropyrimidine

Conditions
ConditionsYield
With fluorine; sodium fluoride In trichlorofluoromethane64%
D-Alanine
338-69-2

D-Alanine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

N-(4,6-Difluoro-2-pyrimidyl)-D-α-alanine

N-(4,6-Difluoro-2-pyrimidyl)-D-α-alanine

B

N-(2,6-Difluoro-4-pyrimidyl)-D-α-alanine

N-(2,6-Difluoro-4-pyrimidyl)-D-α-alanine

Conditions
ConditionsYield
With sodium carbonate In water at 50℃; for 2h;A 63%
B 32%
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

glycine
56-40-6

glycine

A

N-(2,6-Difluoro-4-pyrimidyl)glycine

N-(2,6-Difluoro-4-pyrimidyl)glycine

B

N-(4,6-Difluoro-2-pyrimidyl)glycine
205817-03-4

N-(4,6-Difluoro-2-pyrimidyl)glycine

Conditions
ConditionsYield
With sodium carbonate In water at 50℃; for 2h;A 28%
B 62%
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

3-amino propanoic acid
107-95-9

3-amino propanoic acid

A

N-(2,6-Difluoro-4-pyrimidyl)-β-alanine

N-(2,6-Difluoro-4-pyrimidyl)-β-alanine

B

N-(4,6-Difluoro-2-pyrimidyl)-β-alanine

N-(4,6-Difluoro-2-pyrimidyl)-β-alanine

Conditions
ConditionsYield
With sodium carbonate In water at 50℃; for 2h;A 30%
B 61%
morpholine
110-91-8

morpholine

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

4-morpholino-2,6-difluoropyrimidine

4-morpholino-2,6-difluoropyrimidine

B

2-morpholino-4,6-difluoropyrimidine

2-morpholino-4,6-difluoropyrimidine

Conditions
ConditionsYield
In water at 0 - 10℃; for 1h; Yields of byproduct given;A n/a
B 60%
In water at 0 - 10℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

4-amino-n-butyric acid
56-12-2

4-amino-n-butyric acid

A

N-(2,6-Difluoro-4-pyrimidyl)-γ-aminobutyric acid

N-(2,6-Difluoro-4-pyrimidyl)-γ-aminobutyric acid

B

N-(4,6-Difluoro-2-pyrimidyl)-γ-aminobutyric acid

N-(4,6-Difluoro-2-pyrimidyl)-γ-aminobutyric acid

Conditions
ConditionsYield
With sodium carbonate In water at 50℃; for 2h;A 38%
B 60%
2-(N,N-dimethylamino)ethanol
108-01-0

2-(N,N-dimethylamino)ethanol

2,4,6-trifluoropyrimidine
696-82-2

2,4,6-trifluoropyrimidine

A

2-((4,6-difluoropyrimidin-2-yl)oxy)-N,N-dimethylethanamine

2-((4,6-difluoropyrimidin-2-yl)oxy)-N,N-dimethylethanamine

B

2-((2,6-difluoropyrimidin-4-yl)oxy)-N,N-dimethylethanamine

2-((2,6-difluoropyrimidin-4-yl)oxy)-N,N-dimethylethanamine

Conditions
ConditionsYield
In tetrahydrofuran at -78 - 20℃; for 1h;A 55%
B 5%

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