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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethyl N-methylamidomalonate

Cas:71510-95-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top quality CAS 71510-95-7 with best price

Cas:71510-95-7

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 71510-95-7 Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Propanoic acid,3-(methylamino)-3-oxo-, ethyl ester

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Ethyl-N-Methyl Malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

71510-95-7

Cas:71510-95-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Ethyl-N-methyl malonamide Basic information Product Name: Ethyl-N-methyl malonamide Synonyms: Ethyl 3-(methylamino)-3-oxopropanoate;N-METHYL-MALONAMIC ACID ETHYL ESTER;3-(Methylamino)-3-oxo-propanoic acid ethyl ester;ETHYL 1-METHYL AMIDOMALONAT

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Ethyl N-Methylmalonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-carboethoxy-n-methyl-acetamide

Cas:71510-95-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediate

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home

Ethyl-N-methyl malonamide china manufacture

Cas:71510-95-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Ethyl-N-Methyl Malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Cartoon Ingredients Co., Ltd

Cartoon Ingredients Co.,Ltd.is located in NanJing, the capital of Jiangsu Province.with Convenient traffic As a manufacturer, the company mainly engaged in providing Food ingredients, Herbal extracts, Vitamins, APIs and Fine chemicals &a

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Ethyl-N-Methyl MalonaMide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Ethyl-N-methylmalonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Ethyl-N-methyl malonamide CAS No.71510-95-7

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Ethyl-N-methyl malonamide cas 71510-95-7Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Ethyl-N-methyl malonamide cas 71510-95-7

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Ethyl-N-methyl malonamide

Cas:71510-95-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

C14H13FN2O

C14H13FN2O

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione
188302-25-2

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
Stage #1: C14H13FN2O With C31H44N4O4; ytterbium(III) triflate In dichloromethane at 35℃; for 0.5h; Molecular sieve; Inert atmosphere;
Stage #2: 2-carboethoxy-N-methyl-acetamide With triethylamine In dichloromethane at 40℃; for 72h; Reagent/catalyst; Solvent; Concentration; Inert atmosphere; Molecular sieve; stereoselective reaction;
90%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole

p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole

(3R,4S)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

(3R,4S)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
Stage #1: 2-carboethoxy-N-methyl-acetamide; p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole With C32H46N4O4; ytterbium(III) triflate In toluene at 35℃; for 0.333333h;
Stage #2: With triethylamine In toluene at 30 - 50℃; Reagent/catalyst; Solvent;
85.5%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

2-carboisopropoxy-N-methyl-acetamide
323203-14-1

2-carboisopropoxy-N-methyl-acetamide

Conditions
ConditionsYield
In isopropyl alcohol; mineral oil82%
In isopropyl alcohol; mineral oil82%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

3-[3-(4-fluorophenyl)acryloyl]-(R)-4-phenyl-oxazolidin-2-one

3-[3-(4-fluorophenyl)acryloyl]-(R)-4-phenyl-oxazolidin-2-one

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione
188302-25-2

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
Stage #1: 2-carboethoxy-N-methyl-acetamide With sodium hydride In dimethyl sulfoxide at 20℃; Inert atmosphere;
Stage #2: 3-[3-(4-fluorophenyl)acryloyl]-(R)-4-phenyl-oxazolidin-2-one In dimethyl sulfoxide at 20℃; Inert atmosphere;
80%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

4-nitrophenyl 3-phenylprop-2-ynoate

4-nitrophenyl 3-phenylprop-2-ynoate

(Z)-ethyl 5-benzylidene-2-(methylamino)-4-oxo-4,5-dihydrofuran-3-carboxylate

(Z)-ethyl 5-benzylidene-2-(methylamino)-4-oxo-4,5-dihydrofuran-3-carboxylate

Conditions
ConditionsYield
With 1,3-bis(mesityl)imidazolium chloride; N-ethyl-N,N-diisopropylamine; lithium chloride In acetonitrile at 65℃; for 10h; Reagent/catalyst; Molecular sieve; Inert atmosphere; regioselective reaction;77%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

4-Methylamino-1,3-dihydro-benzo[b][1,4]diazepin-2-one
91598-13-9

4-Methylamino-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Conditions
ConditionsYield
With trichlorophosphate at 110℃; for 4h;59.1%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

1,2,4-triaminopyridin-1-ium 2,4,6-trimethylbenzenesulfonate

1,2,4-triaminopyridin-1-ium 2,4,6-trimethylbenzenesulfonate

2-(7-amino-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-N-methylacetamide

2-(7-amino-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-N-methylacetamide

Conditions
ConditionsYield
With sodium hydroxide In methanol Reflux;39.4%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

1,2,4-triamino-4-bromopyridin-1-ium-2,4,6-trimethylbenzenesulfonate

1,2,4-triamino-4-bromopyridin-1-ium-2,4,6-trimethylbenzenesulfonate

2-(7-amino-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-N-methylacetamide

2-(7-amino-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-N-methylacetamide

Conditions
ConditionsYield
With sodium hydroxide In methanol Reflux;39.4%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

ethyl 2-bromo-3-(methylamino)-3-oxopropanoate

ethyl 2-bromo-3-(methylamino)-3-oxopropanoate

Conditions
ConditionsYield
With sodium hydrogen sulfate; N-Bromosuccinimide In tetrahydrofuran at 0℃; Inert atmosphere;20%
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

trans 3-ethoxycarbonyl-4-(4'-fluorophenyl)-N-methyl-piperidine-2,6-dione
202534-94-9

trans 3-ethoxycarbonyl-4-(4'-fluorophenyl)-N-methyl-piperidine-2,6-dione

Conditions
ConditionsYield
With sodium methylate; acetic acid In water; ethyl acetate
With sodium methylate; acetic acid In water; ethyl acetate
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

3-phenyl-propenal
104-55-2

3-phenyl-propenal

A

C15H19NO4

C15H19NO4

B

C15H19NO4
323203-12-9

C15H19NO4

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; optical yield given as %ee; enantioselective reaction;
(E)-3-phenylpropenal
14371-10-9

(E)-3-phenylpropenal

2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

(3R,4S,6S)-ethyl 6-hydroxy-1-methyl-2-oxo-4-phenylpiperidine-3-carboxylate

(3R,4S,6S)-ethyl 6-hydroxy-1-methyl-2-oxo-4-phenylpiperidine-3-carboxylate

Conditions
ConditionsYield
With (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %ee; enantioselective reaction;
3-(4-nitrophenyl)-propenal
49678-08-2

3-(4-nitrophenyl)-propenal

2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

(3S,4R,6R)-ethyl 6-hydroxy-1-methyl-4-(4-nitrophenyl)-2-oxopiperidine-3-carboxylate
1345157-71-2

(3S,4R,6R)-ethyl 6-hydroxy-1-methyl-4-(4-nitrophenyl)-2-oxopiperidine-3-carboxylate

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %ee; enantioselective reaction;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

4-chlorocinnamaldehyde
1075-77-0

4-chlorocinnamaldehyde

A

(3S,4R,6R)-ethyl 4-(4-chlorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate
1345157-65-4

(3S,4R,6R)-ethyl 4-(4-chlorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

B

ethyl 4-(4-chlorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

ethyl 4-(4-chlorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %de; enantioselective reaction;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

trans-4-bromocinnamaldehyde
49678-04-8

trans-4-bromocinnamaldehyde

A

(3S,4R,6R)-ethyl 4-(4-bromophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate
1345157-68-7

(3S,4R,6R)-ethyl 4-(4-bromophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

B

ethyl 4-(4-bromophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

ethyl 4-(4-bromophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %de; enantioselective reaction;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

3-(4-fluoro-phenyl)-propenal
51791-26-5, 24654-55-5

3-(4-fluoro-phenyl)-propenal

A

ethyl 4-(4-fluorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

ethyl 4-(4-fluorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

B

ethyl 4-(4-fluorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

ethyl 4-(4-fluorophenyl)-6-hydroxy-1-methyl-2-oxopiperidine-3-carboxylate

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %de; enantioselective reaction;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

3-(4-methylphenyl)acrylaldehyde
1504-75-2

3-(4-methylphenyl)acrylaldehyde

A

(3S,4R,6R)-ethyl 6-hydroxy-1-methyl-2-oxo-4-p-tolylpiperidine-3-carboxylate
1345157-60-9

(3S,4R,6R)-ethyl 6-hydroxy-1-methyl-2-oxo-4-p-tolylpiperidine-3-carboxylate

B

ethyl 6-hydroxy-1-methyl-2-oxo-4-p-tolylpiperidine-3-carboxylate

ethyl 6-hydroxy-1-methyl-2-oxo-4-p-tolylpiperidine-3-carboxylate

Conditions
ConditionsYield
With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; potassium acetate In 2,2,2-trifluoroethanol at 20℃; for 14h; optical yield given as %de; enantioselective reaction;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole

p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione
188302-25-2

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
Stage #1: 2-carboethoxy-N-methyl-acetamide; p-fluorocinnamoyl-3,5-dimethyl-1H-pyrazole With C32H46N4O4; ytterbium(III) triflate In dichloromethane at 35℃; for 0.333333h;
Stage #2: With triethylamine In dichloromethane at 30 - 50℃; Reagent/catalyst;
51 g
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

C14H14N2O
37612-74-1

C14H14N2O

C15H17NO4

C15H17NO4

B

(3R,4S)-3-ethoxycarbonyl-4-(4-phenyl)-N-methylpiperidine-2,6-dione

(3R,4S)-3-ethoxycarbonyl-4-(4-phenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
With C31H44N4O4; triethylamine; ytterbium(III) triflate In 1,2-dichloro-ethane at 40℃; for 72h; Molecular sieve; Inert atmosphere; Overall yield = 87 %; stereoselective reaction;A n/a
B n/a
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

C14H13FN2O

C14H13FN2O

A

(3R,4S)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

(3R,4S)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

B

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione
188302-25-2

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

C15H16FNO4

C15H16FNO4

Conditions
ConditionsYield
With (2S,2'S)-1,1'-(propane-1,3-diyl)bis(N-(2,6-dimethylphenyl)pyrrolidine-2-carboxamide)-N,N'-dioxide; triethylamine; ytterbium(III) triflate In dichloromethane at 35℃; for 72h; Inert atmosphere; Overall yield = 10 %;A n/a
B n/a
C n/a
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

C14H13FN2O

C14H13FN2O

A

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione
188302-25-2

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

C15H16FNO4

C15H16FNO4

Conditions
ConditionsYield
With C35H52N4O4; triethylamine; ytterbium(III) triflate In dichloromethane at 35℃; for 72h; Inert atmosphere; Overall yield = 9 %;A n/a
B n/a
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

C14H13FN2O

C14H13FN2O

trans 3-ethoxycarbonyl-4-(4'-fluorophenyl)-N-methyl-piperidine-2,6-dione
202534-94-9

trans 3-ethoxycarbonyl-4-(4'-fluorophenyl)-N-methyl-piperidine-2,6-dione

Conditions
ConditionsYield
Stage #1: 2-carboethoxy-N-methyl-acetamide With potassium tert-butylate In dichloromethane at 20℃; for 0.333333h; Inert atmosphere;
Stage #2: C14H13FN2O In dichloromethane at 20℃; for 24h; Inert atmosphere;
2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

3,5-dimethyl-1-[3-(4-chlorophenyl)propanonyl]pyrazole

3,5-dimethyl-1-[3-(4-chlorophenyl)propanonyl]pyrazole

C15H16ClNO4

C15H16ClNO4

B

(3R,4S)-3-ethoxycarbonyl-4-(4-chlorophenyl)-N-methylpiperidine-2,6-dione

(3R,4S)-3-ethoxycarbonyl-4-(4-chlorophenyl)-N-methylpiperidine-2,6-dione

Conditions
ConditionsYield
With C31H44N4O4; triethylamine; ytterbium(III) triflate In 1,2-dichloro-ethane at 40℃; for 72h; Molecular sieve; Inert atmosphere; Overall yield = 92 %; stereoselective reaction;A n/a
B n/a
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

2-carboethoxy-N-methyl-acetamide
71510-95-7

2-carboethoxy-N-methyl-acetamide

ethyl 1,5-dimethyl-2,4,6-pyridin-3-carboxylate

ethyl 1,5-dimethyl-2,4,6-pyridin-3-carboxylate

Conditions
ConditionsYield
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide; toluene at 20 - 35℃; for 56h; Temperature;

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