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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyridine,2-bromo-3-methoxy-6-nitro- 76066-07-4

Cas:76066-07-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-Bromo-3-methoxy-6-nitropyridine CAS:76066-07-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

2-Bromo-3-methoxy-6-nitropyridine CAS:76066-07-4

Cas:76066-07-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyridine,2-bromo-3-methoxy-6-nitro-

Cas:76066-07-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyridine,2-bromo-3-methoxy-6-nitro-

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pyridine,2-bromo-3-methoxy-6-nitro-

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pyridine,2-bromo-3-methoxy-6-nitro-

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine Application:TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

2-Bromo-3-methoxy-6-nitropyridine CAS No.76066-07-4

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2-BROMO-3-METHOXY-6-NITROPYRIDINEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-BROMO-3-METHOXY-6-NITROPYRIDINE

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

76066-07-4 Application:intermediate

2-bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridineAppearance:White powder Storage:room temperature Package:as requested Application:Intermediates Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport)

TIANFU CHEM 2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

76066-07-4

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2-Bromo-3-methoxy-6-nitropyridine 76066-07-4

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2-Bromo-3-methoxy-6-nitropyridine 76066-07-4

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2-Bromo-3-methoxy-6-nitropyridine

Cas:76066-07-4

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-bromo-3-methoxypyridine
24100-18-3

2-bromo-3-methoxypyridine

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 2 - 55℃;83%
With sulfuric acid; nitric acid at 60℃; for 1h;80%
With sulfuric acid; nitric acid at 50℃; for 4h;80%
3-HYDROXYPYRIDINE
109-00-2

3-HYDROXYPYRIDINE

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 35 percent / Br2, 10percent aq. NaOH / 24 h
2: 1.) NaOCH3 / 1.) MeOH, DMF; 2.) DMF, RT, 1.5 h
3: 80 percent / fuming HNO3, conc. H2SO4 / 1 h / 60 °C
View Scheme
2-bromo-pyridin-3-ol
6602-32-0

2-bromo-pyridin-3-ol

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) NaOCH3 / 1.) MeOH, DMF; 2.) DMF, RT, 1.5 h
2: 80 percent / fuming HNO3, conc. H2SO4 / 1 h / 60 °C
View Scheme
2-bromo-3-methoxypyridine
24100-18-3

2-bromo-3-methoxypyridine

sulfuric acid
7664-93-9

sulfuric acid

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

Conditions
ConditionsYield
With nitric acid In water
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2-amino-5-methoxypyridine
10167-97-2

2-amino-5-methoxypyridine

Conditions
ConditionsYield
With hydrazine; palladium 10% on activated carbon In ethanol for 0.75h; Heating / reflux;96%
With hydrazine; palladium 10% on activated carbon In ethanol; water for 0.75h; Heating / reflux;96%
With hydrazine hydrate; palladium on activated charcoal In ethanol for 1.5h; Heating;95%
methanol
67-56-1

methanol

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2,3-dimethoxy-6-nitropyridine
79491-44-4

2,3-dimethoxy-6-nitropyridine

Conditions
ConditionsYield
With sodium In dimethyl sulfoxide at 30℃; for 2h;81%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-methoxy-6-nitropicolinonitrile

3-methoxy-6-nitropicolinonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 120℃; for 4h;78%
sodium methylate
124-41-4

sodium methylate

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2,3-dimethoxy-6-nitropyridine
79491-44-4

2,3-dimethoxy-6-nitropyridine

Conditions
ConditionsYield
In methanol; dimethyl sulfoxide at 20 - 35℃; for 49.5h;76%
methanol
67-56-1

methanol

sodium methylate
124-41-4

sodium methylate

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2,3-dimethoxy-6-nitropyridine
79491-44-4

2,3-dimethoxy-6-nitropyridine

Conditions
ConditionsYield
In dimethyl sulfoxide at 20 - 35℃; for 49.5h;76%
2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
72824-04-5

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2-allyl-3-methoxy-6-nitropyridine
1446792-80-8

2-allyl-3-methoxy-6-nitropyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 66℃; for 20h;75%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In tetrahydrofuran at 66℃; for 20h;75%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In tetrahydrofuran at 66℃; for 20h;75%
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2-isopropenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
126726-62-3

2-isopropenyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

3-methoxy-6-nitro-2-(prop-1-en-2-yl)pyridine
1446792-90-0

3-methoxy-6-nitro-2-(prop-1-en-2-yl)pyridine

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In water; dimethyl amine at 150℃; for 0.333333h; Microwave irradiation; Sealed tube;66%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In aq. phosphate buffer; N,N-dimethyl acetamide; water at 150℃; for 0.333333h;66%
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl acetamide; water at 150℃; for 0.333333h; Microwave irradiation; Sealed tube;66%
sodium hydrosulfite (Na2 Ss O4)

sodium hydrosulfite (Na2 Ss O4)

2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

6-bromo-5-methoxypyridin-2-amine
79491-43-3

6-bromo-5-methoxypyridin-2-amine

Conditions
ConditionsYield
With ammonium hydroxide In dichloromethane; water50%
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

6-bromo-5-methoxypyridin-2-amine
79491-43-3

6-bromo-5-methoxypyridin-2-amine

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In ethanol under 760 Torr;46%
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

2-bromo-5-methoxypyridine
105170-27-2

2-bromo-5-methoxypyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

5-methoxy-2-pyridinecarboxaldehyde
22187-96-8

5-methoxy-2-pyridinecarboxaldehyde

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: aq. HCl
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-(5-Methoxypyridin-2-ylmethyl)-1-methyl-2,3-dihydro-1H-indol
325796-80-3

3-(5-Methoxypyridin-2-ylmethyl)-1-methyl-2,3-dihydro-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 40 percent / tetrahydrofuran; hexane / -100 °C
4.1: 85 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 1.5 h / 20 °C / 52504.2 Torr
5.1: 71 percent / NaBH3CN; TFA / acetic acid
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-(5-Methoxypyridin-2-ylmethyl)-2,3-dihydroindol-1-carbonsaeuremethylester
325796-82-5

3-(5-Methoxypyridin-2-ylmethyl)-2,3-dihydroindol-1-carbonsaeuremethylester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: NaBH3CN / methanol; acetic acid / 3.5 h
4.2: 82 percent / NaBH3CN; TFA / 16.5 h
5.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
6.1: 94 percent / aq. NaHCO3 / diethyl ether / 0 °C
View Scheme
Multi-step reaction with 7 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
5.1: 86 percent / TFA; NaBH3CN / acetic acid
6.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
7.1: 94 percent / aq. NaHCO3 / diethyl ether / 0 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

5-Methoxy-2-(1-methoxycarbonyl-2,3-dihydro-1H-indol-3-ylmethyl)-1-methylpyridiniumiodid

5-Methoxy-2-(1-methoxycarbonyl-2,3-dihydro-1H-indol-3-ylmethyl)-1-methylpyridiniumiodid

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: NaBH3CN / methanol; acetic acid / 3.5 h
4.2: 82 percent / NaBH3CN; TFA / 16.5 h
5.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
6.1: 94 percent / aq. NaHCO3 / diethyl ether / 0 °C
7.1: 92 percent / acetone / 120 h
View Scheme
Multi-step reaction with 8 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
5.1: 86 percent / TFA; NaBH3CN / acetic acid
6.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
7.1: 94 percent / aq. NaHCO3 / diethyl ether / 0 °C
8.1: 92 percent / acetone / 120 h
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1‐(5‐methoxypyridin‐2‐yl)ethan‐1‐one
325796-84-7

1‐(5‐methoxypyridin‐2‐yl)ethan‐1‐one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: tetrahydrofuran; hexane / -100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-(5-Methoxypyridin-2-ylmethyl)-2,3-dihydro-1H-indol
325796-81-4

3-(5-Methoxypyridin-2-ylmethyl)-2,3-dihydro-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: NaBH3CN / methanol; acetic acid / 3.5 h
4.2: 82 percent / NaBH3CN; TFA / 16.5 h
5.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
View Scheme
Multi-step reaction with 6 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
5.1: 86 percent / TFA; NaBH3CN / acetic acid
6.1: 95 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 45003.6 Torr
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-(5-Methoxypyridin-2-ylmethyl)-1H-indol

3-(5-Methoxypyridin-2-ylmethyl)-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 10 percent / tetrahydrofuran; hexane / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-(1H-Indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol
325796-74-5

1-(1H-Indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 10 percent / tetrahydrofuran; hexane / -100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-(1-Methoxymethyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol
325796-73-4

1-(1-Methoxymethyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 40 percent / tetrahydrofuran; hexane / -100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-Methoxymethyl-3-(5-methoxypyridin-2-ylmethyl)-1H-indol
325796-77-8

1-Methoxymethyl-3-(5-methoxypyridin-2-ylmethyl)-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 40 percent / tetrahydrofuran; hexane / -100 °C
4.1: 85 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 1.5 h / 20 °C / 52504.2 Torr
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

3-[1-Hydroxy-1-(5-methoxypyridin-2-yl)-methyl]-indol-1-carbonsaeuremethylester

3-[1-Hydroxy-1-(5-methoxypyridin-2-yl)-methyl]-indol-1-carbonsaeuremethylester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / -105 - -100 °C
3.2: 34 percent / tetrahydrofuran; hexane / -100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-1H-indol
325796-76-7

1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-2,3-dihydro-1H-indol
325796-79-0

1-Benzyl-3-(5-methoxypyridin-2-ylmethyl)-2,3-dihydro-1H-indol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: NaBH3CN / methanol; acetic acid / 3.5 h
4.2: 82 percent / NaBH3CN; TFA / 16.5 h
View Scheme
Multi-step reaction with 5 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: 100 percent / H2 / 5 percent Pd/C / ethanol; aq. HCl / 3 h / 20 °C / 52504.2 Torr
5.1: 86 percent / TFA; NaBH3CN / acetic acid
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol
325796-72-3

1-(1-Benzyl-1H-indol-3-yl)-1-(5-methoxypyridin-2-yl)-methanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

C23H24BN3O

C23H24BN3O

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: NaBH3CN / methanol; acetic acid / 3.5 h
4.2: NaBH3CN; TFA / 16.5 h
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

Bis-(1-benzylindol-3-yl)-5-methoxypyridin-2-yl-methan

Bis-(1-benzylindol-3-yl)-5-methoxypyridin-2-yl-methan

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating
2.1: Br2 / aq. HBr / cooling
2.2: 67 percent / aq. NaNO2 / 0.5 h / cooling
3.1: BuLi / tetrahydrofuran; hexane / 0.33 h / -105 - -100 °C
3.2: 60 percent / tetrahydrofuran; hexane / 1.5 h / -100 °C
4.1: aq. HCl
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

5'-Hydroxypiroxicam
77459-78-0

5'-Hydroxypiroxicam

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 59 percent / H2, NaOH / 10percent Pd/C / ethanol
2: 59 percent / xylene / 24 h / Heating
3: 30percent HBr, AcOH / 120 h / 100 °C
View Scheme
2-bromo-3-methoxy-6-nitropyridine
76066-07-4

2-bromo-3-methoxy-6-nitropyridine

N-(5'-methoxy-2'-pyridyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
76066-12-1

N-(5'-methoxy-2'-pyridyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 59 percent / H2, NaOH / 10percent Pd/C / ethanol
2: 59 percent / xylene / 24 h / Heating
View Scheme

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