Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryItems Standard Result Appearance yellowish crystals powder Comply Coupling value 98%min
Cas:78287-27-1
Min.Order:1 Kilogram
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Type:Manufacturers
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Cas:78287-27-1
Min.Order:1 Gram
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Type:Manufacturers
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:78287-27-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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Min.Order:1 Kilogram
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Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:78287-27-1
Min.Order:0
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inquiryHigh purity 7-Ethyl-Camptothecin with high quality and lowest pricre cas:78287-27-1 1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitiv
Cas:78287-27-1
Min.Order:10 Gram
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Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryBeluga chemical professional supply High quality 7-Ethylcamptothecin CAS 78287-27-1 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in C
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Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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Min.Order:1 Kilogram
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Cas:78287-27-1
Min.Order:25 Gram
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inquiryPRODUCT DETAILS
Cas:78287-27-1
Min.Order:500 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Min.Order:1 Gram
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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Min.Order:10 Gram
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Min.Order:1 Metric Ton
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Min.Order:1 Kilogram
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Type:Trading Company
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Min.Order:1 Gram
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:78287-27-1
Min.Order:1 Metric Ton
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Type:Trading Company
inquiryLocated in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; acetic acid at -5 - 5℃; for 0.166667h; Temperature; | 95.4% |
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate In water for 3h; Ambient temperature; | 77% |
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate for 3h; Ambient temperature; | 77% |
Conditions | Yield |
---|---|
With sulfuric acid; iron(II) sulfate; acetic acid In water at 0℃; for 0.5h; | 83.3% |
Acetic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester
A
7-ethylcamptothecin
B
(S)-2-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-2H,4H-2,6,12a-triaza-dibenzo[b,h]fluorene-3,13-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 2.5h; Heating; | A 74% B 11% |
Conditions | Yield |
---|---|
With tris(2,2'-bipyridyl)ruthenium dichloride; 1-acetoxy-1,2-benziodoxol-3-one at 30℃; for 48h; Minisci Aromatic Substitution; Inert atmosphere; Irradiation; | 60% |
propan-1-ol
camptothecin
A
7-ethylcamptothecin
B
7(3-Hydroxy-1-propyl)camptothecin
C
7-(1-Hydroxy-2-propyl)camptothecin
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate In water for 3h; Ambient temperature; | A 40% B 12% C 22% |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate In water; acetic acid for 48h; Ambient temperature; | 22% |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; iron(II) sulfate In water for 48h; Ambient temperature; | 13% |
Isobutyric acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester
A
7-ethylcamptothecin
B
(S)-2-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-2H,4H-2,6,12a-triaza-dibenzo[b,h]fluorene-3,13-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 2.5h; Heating; | A 10 % Chromat. B 16 % Chromat. |
Benzoic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester
A
7-ethylcamptothecin
B
(S)-2-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-2H,4H-2,6,12a-triaza-dibenzo[b,h]fluorene-3,13-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 2.5h; Heating; | A 38 % Chromat. B 36 % Chromat. |
4-Methoxy-benzoic acid 7-[(S)-1-(2-dimethylamino-ethylcarbamoyl)-1-hydroxy-propyl]-12-ethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-8-ylmethyl ester
A
7-ethylcamptothecin
B
(S)-2-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-2H,4H-2,6,12a-triaza-dibenzo[b,h]fluorene-3,13-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 2.5h; Heating; | A 20 % Chromat. B 46 % Chromat. |
A
7-ethylcamptothecin
B
(S)-2-Amino-4,11-diethyl-4-hydroxy-1,12-dihydro-2H,4H-2,6,12a-triaza-dibenzo[b,h]fluorene-3,13-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol for 2.5h; Heating; | A 42 % Chromat. B 46 % Chromat. |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; acetic acid In water |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; propionic acid In water |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide In water |
Conditions | Yield |
---|---|
With sulfuric acid; dihydrogen peroxide; acetic acid In water |
7-ethyl-18,19-dehydrocamptothecin
7-ethylcamptothecin
Conditions | Yield |
---|---|
With hydrogen; palladium 10% on activated carbon In 1,4-dioxane; ethanol at 20℃; for 1 - 7h; |
Conditions | Yield |
---|---|
With ferrous(II) sulfate heptahydrate; sulfuric acid; dihydrogen peroxide In water at 0℃; for 8h; |
7-ethylcamptothecin
7-ethyl-1,2,6,7-tetrahydro-20-(S)-camptothecin
Conditions | Yield |
---|---|
With hydrogen; N113 In acetic acid at 110℃; under 15001.5 Torr; for 6h; Autoclave; | 96% |
With hydrogen; dimethyl sulfoxide; platinum on carbon In acetic acid at 25 - 65℃; under 3750.38 Torr; for 43.5h; |
Conditions | Yield |
---|---|
With dmap In dichloromethane at 20℃; for 20h; | 92% |
Conditions | Yield |
---|---|
Stage #1: 5-fluorouracil-1-acetic acid With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 0℃; Stage #2: 7-ethylcamptothecin at 0 - 20℃; Inert atmosphere; | 88% |
Conditions | Yield |
---|---|
Stage #1: uracilacetic acid With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 0℃; Stage #2: 7-ethylcamptothecin at 0 - 20℃; Inert atmosphere; | 86.6% |
7-ethylcamptothecin
2-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid
Conditions | Yield |
---|---|
Stage #1: 2-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 0℃; Stage #2: 7-ethylcamptothecin at 0 - 20℃; Inert atmosphere; | 86.6% |
7-ethylcamptothecin
isopropylamine
Conditions | Yield |
---|---|
for 1.5h; Heating; | 86% |
Conditions | Yield |
---|---|
Stage #1: 1-carboxymethyl-5-chlorouracil With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 0℃; Stage #2: 7-ethylcamptothecin at 0 - 20℃; Inert atmosphere; | 84% |
p-nitrobenzotrifluoride
7-ethylcamptothecin
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 2 - 20℃; for 2.25h; | 82% |
7-ethylcamptothecin
7-ethyl-10-hydroxycamptothecin
Conditions | Yield |
---|---|
With dihydrogen peroxide; acetic anhydride; acetic acid at 50℃; | 80.3% |
Multi-step reaction with 2 steps 1: 77.7 percent / 30percent aq. H2O2, acetic acid / 3.5 h / 70 - 80 °C 2: 49.1 percent / 1 N aq. H2SO4 / dioxane / 0.5 h / Irradiation View Scheme | |
Multi-step reaction with 2 steps 1: 78 percent / 30percent H2O2 / acetic acid / 3.5 h / 70 - 80 °C 2: 49 percent / 1 N H2SO4 / dioxane / 0.5 h / Irradiation View Scheme | |
Stage #1: 7-ethylcamptothecin With hydrogen; acetic acid; platinum(IV) oxide In dimethyl sulfoxide at 50 - 60℃; under 3102.97 Torr; for 10h; Stage #2: With [bis(acetoxy)iodo]benzene In water at 20℃; for 3h; | |
Multi-step reaction with 2 steps 1: acetic acid; dihydrogen peroxide / 8 h / 80 °C 2: sulfuric acid; water / 1,4-dioxane; acetonitrile / Inert atmosphere; Irradiation View Scheme |
Conditions | Yield |
---|---|
Stage #1: (5-bromouracil)acetic acid With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 0℃; Stage #2: 7-ethylcamptothecin at 0 - 20℃; Inert atmosphere; | 80% |
7-ethylcamptothecin
7-Ethylcamptothecin 1-Oxide
Conditions | Yield |
---|---|
With dihydrogen peroxide In acetic acid at 70 - 80℃; for 3.5h; | 78% |
With dihydrogen peroxide; acetic acid at 70 - 80℃; for 3.5h; | 77.7% |
With dihydrogen peroxide; acetic acid at 80℃; for 8h; | 72% |
7-ethylcamptothecin
3-nitrobenzoic acid
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 2 - 20℃; for 2.25h; | 77.1% |
7-ethylcamptothecin
N,N-dimethylethylenediamine
(S)-N-(2-Dimethylamino-ethyl)-2-(12-ethyl-8-hydroxymethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-7-yl)-2-hydroxy-butyramide
Conditions | Yield |
---|---|
at 50℃; for 1.5h; | 71% |
Conditions | Yield |
---|---|
Stage #1: 7-ethylcamptothecin With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h; Inert atmosphere; Stage #2: propargyl bromide In N,N-dimethyl-formamide Inert atmosphere; Reflux; | 70% |
7-ethylcamptothecin
Conditions | Yield |
---|---|
With hydrazine hydrate for 2h; Heating; | 64% |
7-ethylcamptothecin
7-ethyl-14-nitro-camptothecin
Conditions | Yield |
---|---|
With nitric acid; acetic anhydride at 0℃; for 1h; | 63.4% |
Conditions | Yield |
---|---|
With dmap; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere; | 57% |
7-ethylcamptothecin
N-(+)-biotinyl-6-aminocaproic acid
Conditions | Yield |
---|---|
With dmap; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere; | 56% |
Conditions | Yield |
---|---|
Stage #1: C17H20N2O4S2 With pyridine In tetrahydrofuran for 0.0833333h; Inert atmosphere; Cooling with ice; Stage #2: With trichloromethyl chloroformate In tetrahydrofuran for 1h; Stage #3: C28H29ClNO2(1+)*I(1-); 7-ethylcamptothecin With dmap; triethylamine In tetrahydrofuran at 20℃; for 12h; Inert atmosphere; Cooling with ice; | 31% |
7-ethylcamptothecin
12-Ethyl-8-methyl-7-propionyl-11H-indolizino[1,2-b]quinolin-9-one
Conditions | Yield |
---|---|
With sodium azide; 18-crown-6 ether In N,N-dimethyl-formamide at 120℃; for 4h; | 20% |
7-ethylcamptothecin
(S)-2-(12-Ethyl-8-hydroxymethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-7-yl)-2-hydroxy-butyric acid hydrazide
Conditions | Yield |
---|---|
With hydrazine hydrate for 0.5h; Ambient temperature; |
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