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Cas:58-85-5
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inquiry1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq
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Superiority KONO is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in
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Cas:58-85-5
Min.Order:100 Gram
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Min.Order:1 Kilogram
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Cas:58-85-5
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Cas:58-85-5
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Item Standard Result Appearance White or almost white crystalline powder Conform Identification
Cas:58-85-5
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryHebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ
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inquiryUnique advantages for D-biotin/VITAMIN H Cas 58-85-5 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:2-8°C Package:1kg/foil bag, 25kg/drum or
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inquiry18-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China
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Vitamin H Product name: Vitamin H Specifications and models: 2%,98% Relative molecular weight: 244.31 Molecular formula: C10H16N2O3S CAS#: 58-85-5 Properties: light yellow crystal powder, soluble in water, stable in neutral solution Scope o
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Cas:58-85-5
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inquiryProduct Name:D-Biotin Appearance:White Powder Assay: 99% Shipping method: Fedex, DHL, TNT, Sea, Air or as you wish Package: Aluminum Foil Bag Hot Market: Europe, America, Asia Usage: Food,Cosmetics,Dietary Supplements,Medicines,Pharmaceuticals
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inquiryGMP factoryFull experience of large numbers containers loading in main Chinese seaports Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Rich experience for
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate; tin(IV) chloride at 150℃; under 300.03 Torr; for 3.5h; Temperature; Pressure; Reagent/catalyst; Autoclave; | 97.5% |
(3aS,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2,4-dione
potassium thioacetate
biotin
Conditions | Yield |
---|---|
In water at 0 - 60℃; Temperature; | 97% |
biotin
Conditions | Yield |
---|---|
With hydrogenchloride; sodium dithionite; water; sodium hydroxide In water at 55 - 90℃; for 0.5h; Reagent/catalyst; | 95.8% |
(3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid
biotin
Conditions | Yield |
---|---|
Stage #1: (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid With boron tribromide In dichloromethane at -5 - 50℃; for 1.16667h; Inert atmosphere; Stage #2: With hydrogenchloride In water Temperature; Solvent; | 95% |
Stage #1: (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid With water; hydrogen bromide In xylene for 20h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; bis(trichloromethyl) carbonate; pyrographite Product distribution / selectivity; more than 3 stages; | 92% |
Stage #1: (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid With water; hydrogen bromide In xylene for 20h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; bis(trichloromethyl) carbonate; pyrographite Product distribution / selectivity; more than 3 stages; | 92% |
(3aS,4S,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-one-4-ylpentane nitrile
biotin
Conditions | Yield |
---|---|
Stage #1: (3aS,4S,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-one-4-ylpentane nitrile With water; hydrogen bromide In xylene for 20h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; bis(trichloromethyl) carbonate; pyrographite Product distribution / selectivity; more than 3 stages; | 95% |
With water; hydrogen bromide for 10h; Reflux; Inert atmosphere; | 80% |
Multi-step reaction with 2 steps 1: aq. HBr / toluene / 40 h / Heating 2: 22 g / aq. NaOH / toluene; methoxybenzene / 6 h / 30 °C View Scheme |
Conditions | Yield |
---|---|
With sodium hydroxide at 20℃; for 10h; pH=9-11; | 93% |
bis(trichloromethyl) carbonate
biotin
Conditions | Yield |
---|---|
With potassium hydroxide at 20℃; for 10h; pH=9-11; Reagent/catalyst; | 92% |
Conditions | Yield |
---|---|
With methanetrisulfonic acid at 170℃; under 3000.3 - 4500.45 Torr; Reagent/catalyst; Pressure; Temperature; Autoclave; | 91.67% |
(3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid ethyl ester
biotin
Conditions | Yield |
---|---|
Stage #1: (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid ethyl ester With water; hydrogen bromide In xylene for 20h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; bis(trichloromethyl) carbonate; pyrographite Product distribution / selectivity; more than 3 stages; | 90% |
With sulfuric acid; water; acetic acid at 20 - 80℃; | 82% |
With methanesulfonic acid In 1,3,5-trimethyl-benzene | 74% |
Stage #1: (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-5-ylidene)pentanoic acid ethyl ester With hydrogen bromide for 48h; Substitution; Heating; Stage #2: With sodium hydroxide; chloroformic acid ethyl ester Substitution; Stage #3: With hydrogenchloride Hydrolysis; |
benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate
biotin
Conditions | Yield |
---|---|
Stage #1: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate With water; hydrogen bromide In xylene for 24h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; trichloromethyl chloroformate; pyrographite Product distribution / selectivity; more than 3 stages; | 90% |
Stage #1: benzyl (3aS,4S,6aR)-5-(1,3-dibenzyl-2,3,3a,4,6,6a-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoate With water; hydrogen bromide In xylene for 20h; Heating / reflux; Stage #2: With sodium hydroxide In water pH=12; Stage #3: With hydrogenchloride; trichloromethyl chloroformate; pyrographite Product distribution / selectivity; more than 3 stages; | 90% |
biotin
Conditions | Yield |
---|---|
Stage #1: C19H24N2O3S With palladium on activated charcoal; hydrogen In ethanol at 80 - 85℃; under 11400.8 - 15201 Torr; for 15h; Stage #2: With sodium hydroxide In water at 25 - 30℃; for 5h; Solvent; | 86.9% |
<3aS-(3aα,4β,6aα)>-Hexahydro-2-oxo-3-(phenylmethyl)-1H-thieno<3,4-d>imidazole-4-pentanoic acid methyl ester
biotin
Conditions | Yield |
---|---|
With hydrogen bromide | 85% |
With hydrogen bromide | 85% |
<3aS-(3aα,4β,6aα)>-Hexahydro-2-oxo-1-(phenylmethyl)-1H-thieno<3,4-d>imidazole-4-pentanoic acid methyl ester
biotin
Conditions | Yield |
---|---|
With hydrogen bromide for 2h; Heating; | 85% |
With hydrogen bromide for 2h; Heating; | 85% |
Multi-step reaction with 2 steps 1.1: water; NaOH / methanol / 3 h / 40 °C 2.1: MeSO3H / xylene / 3 h / 135 °C 2.2: 3.06 g / water / 1 h / 10 °C View Scheme |
(3aS,6aR)-1,3-Dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-one-4-ylidenepentanoic acid
biotin
Conditions | Yield |
---|---|
With formic acid; methanesulfonic acid; palladium on activated charcoal for 15h; Catalytic hydrogenation; Debenzylation; Heating; | 85% |
Multi-step reaction with 2 steps 1: H2 / 10percent Pd/C / propan-2-ol / 18 h / 50 °C / 7500.6 Torr 2: 48percent HBr / 2 h / 100 °C View Scheme |
(3aS,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2,4-dione
biotin
Conditions | Yield |
---|---|
Stage #1: ethyl 5-iodopentanoate With bromine; zinc In tetrahydrofuran; toluene at 40℃; for 1h; Stage #2: (3aS,6aR)-1,3-dibenzyltetrahydro-1H-thieno[3,4-d]imidazole-2,4-dione With palladium 10% on activated carbon In tetrahydrofuran; N,N-dimethyl-formamide; toluene at 28 - 40℃; for 5h; Further stages; | 85% |
biotin
Conditions | Yield |
---|---|
With 5'-d(CATAGGTCTTAACTT)-3'; sodium cacodylate In water; isopropyl alcohol at 20℃; pH=7.0; UV-irradiation; | 84% |
N,N'-p-methoxybenzylbiotin
biotin
Conditions | Yield |
---|---|
Stage #1: N,N'-p-methoxybenzylbiotin With hydrogen bromide In toluene for 36h; Reflux; Stage #2: With bis(trichloromethyl) carbonate; methoxybenzene In water for 2h; pH=10; | 83% |
bis(trichloromethyl) carbonate
biotin
Conditions | Yield |
---|---|
With sodium hydroxide In water; toluene at -10 - -5℃; | 82.38% |
biotin
Conditions | Yield |
---|---|
Stage #1: N,N'-dibenzylbiotin methyl ester With hydrogen bromide for 5h; Heating; Stage #2: With sulfuric acid In methanol for 2h; Heating; | 78% |
With hydrogen bromide for 5h; Heating; | 0.041 g |
Conditions | Yield |
---|---|
With sodium hydroxide In water; 1,2-dichloro-ethane at 70 - 80℃; for 4h; pH=10 - 12; | 75.8% |
Conditions | Yield |
---|---|
With 4-methyl-morpholine In dichloromethane; N,N-dimethyl-formamide | A n/a B 62% |
phosgene
(2S,3S,4R)-cis-5-(3,4-diaminotetrahydro-2-thienyl)valeric acid
biotin
biotin
Conditions | Yield |
---|---|
With MANDELIC ACID | |
With (9S)-9-hydroxy-6'-methoxy-1-methyl-cinchonanium hydroxide | |
With L-arginine |
5-[(3aS)-1( oder !3)-benzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4t-yl]-valeric acid
biotin
Conditions | Yield |
---|---|
With ammonia; sodium; xylene | |
Stage #1: 5-[(3aS)-1( oder !3)-benzyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4t-yl]-valeric acid With methanesulfonic acid In xylene at 135℃; for 3h; Stage #2: With water at 10℃; for 1h; Further stages.; | 3.06 g |
With ammonia; sodium; xylene |
phosgene
5-[3,4-bis-(2,2,2-trifluoro-acetylamino)-2,5-dihydro-thiophen-2-yl]-pentanoic acid methyl ester
biotin
Conditions | Yield |
---|---|
(i) H2, Pd/C, (ii) K2CO3, H2O, (iii) /BRN= 1098367/; Multistep reaction; |
[3-((3aS)-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4t-yl)-propyl]-malonic acid
biotin
Conditions | Yield |
---|---|
With sodium hydroxide at 180℃; for 0.5h; |
5-((3aS)-1,3-diacetyl-2-oxo-(3ar,6ac)-hexahydro-thieno[3,4-d]imidazol-4t-yl)-pentanoic acid methyl ester
biotin
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; water |
biotin
Conditions | Yield |
---|---|
With hydrogen bromide for 2h; Heating; |
Conditions | Yield |
---|---|
With hydrogenchloride for 15h; | 100% |
With sulfuric acid | 100% |
Stage #1: methanol With acetyl chloride at 0℃; for 0.166667h; Stage #2: biotin for 1h; Reflux; | 100% |
1-hydroxy-pyrrolidine-2,5-dione
biotin
biotin N-Hydroxysuccinimide ester
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; | 100% |
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere; | 98% |
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; | 95% |
ethanol
biotin
5-[(3aS,4S,6aR)-2-oxo-hexahydro-thieno[3,4-d]imidazol-4-yl]-pentanoic acid ethyl ester
Conditions | Yield |
---|---|
With sulfuric acid | 100% |
With sulfuric acid at 20℃; | 97% |
With hydrogenchloride at 0 - 20℃; for 24h; | 91% |
methyl 10-aminodecanoate hydrochloride
biotin
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide | 100% |
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide | 100% |
tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate
biotin
tert-butyl-N-(2-(2-(2-(5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno(3,4-d)imidazol-6-yl)pentanoylamino)ethoxy)ethoxy)ethyl)carbamate
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1h; | 100% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 17.5h; Inert atmosphere; | 100% |
Stage #1: biotin With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate In dichloromethane at 20℃; for 16h; | 96% |
C2HF3O2*C6H14N4O2
biotin
N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Conditions | Yield |
---|---|
With 2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetratetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide | 100% |
Conditions | Yield |
---|---|
With 2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetratetramethyluronium hexafluorophosphate In N,N-dimethyl-formamide | 100% |
1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-amine
biotin
1-(benzylthio)-3-(tert-butyldiphenylsilyloxy)propan-2-biotinylamide
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 24h; | 100% |
biotin
2-N-biotinyl-N,N-dimethylethan-1,2-diamine
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 24h; | 100% |
Conditions | Yield |
---|---|
Stage #1: biotin With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 40℃; for 0.5h; Inert atmosphere; Stage #2: 3-{2-[2-(3-{[Bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-propoxy)-ethoxy]-ethoxy}-propylamine With triethylamine In N,N-dimethyl-formamide Inert atmosphere; | 100% |
biotin
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetonitrile at 20℃; | 100% |
biotin
Conditions | Yield |
---|---|
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide | 100% |
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Inert atmosphere; | 100% |
biotin
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide | 100% |
1,6-Hexanediamine
biotin
N-(6-aminohexyl)-5-((3aS,4S,6aR)-3a,6a-dimethyl-2-oxohexahydro-1H-thieno[3,4-d] imidazol-4-yl)pentanamide
Conditions | Yield |
---|---|
Stage #1: biotin With di(succinimido) carbonate; triethylamine In N,N-dimethyl-formamide at 20℃; for 6h; Inert atmosphere; Stage #2: 1,6-Hexanediamine In N,N-dimethyl-formamide Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 16h; | 99% |
biotin
C28H35IN8O4S2
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 9h; Sonication; Inert atmosphere; | 99% |
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 9h; Sonication; | 99% |
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 9h; Sonication; | 99% |
Conditions | Yield |
---|---|
Stage #1: biotin With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 48 - 63℃; for 0.583333 - 0.666667h; Stage #2: ethylenediamine In N,N-dimethyl-formamide for 72h; | 99% |
Conditions | Yield |
---|---|
With pyridine; dicyclohexyl-carbodiimide 0-5 deg C, 2.5 h; room temperature, 16 h; | 98% |
With pyridine; dicyclohexyl-carbodiimide at 20 - 50℃; | 95% |
With pyridine; 2`,3`-dideoxycytidine at 20℃; for 24h; | 93% |
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In toluene for 48h; Heating; | 98% |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In dichloromethane at 20℃; Inert atmosphere; | 98% |
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 60℃; for 24h; Inert atmosphere; | 65% |
Conditions | Yield |
---|---|
Stage #1: acetyl chloride In methanol at 0℃; for 0.25h; Stage #2: biotin In methanol at 20℃; for 0.5h; | 98% |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
Fmoc-Trp-OH
Fmoc-Lys-OH
Fmoc-D-Phe-OH
(9-fluorenylmethoxycarbonyl)-L-histidine
biotin
Conditions | Yield |
---|---|
Stage #1: Fmoc-Lys-OH With dmap; diisopropyl-carbodiimide In N,N-dimethyl-formamide for 4h; Stage #2: With piperidine In N,N-dimethyl-formamide for 0.166667h; Stage #3: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Trp-OH; Fmoc-D-Phe-OH; (9-fluorenylmethoxycarbonyl)-L-histidine; biotin Further stages; | 98% |
Conditions | Yield |
---|---|
Stage #1: biotin With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide Stage #2: N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-2,4-dinitroaniline In N,N-dimethyl-formamide for 0.166667h; | 98% |
Conditions | Yield |
---|---|
Stage #1: biotin With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0℃; Inert atmosphere; Stage #2: 4-azidoaniline In N,N-dimethyl-formamide at 0 - 20℃; for 2h; Inert atmosphere; | 98% |
bis(pentafluorophenyl)carbonate
biotin
biotin pentafluorophenyl ester
Conditions | Yield |
---|---|
With 4-methyl-morpholine In N,N-dimethyl-formamide for 2h; | 97% |
biotin
5-((3aS,4S,6aR)-5-oxido-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid
Conditions | Yield |
---|---|
With sodium peroxoborate tetrahydrate; acetic acid at 20℃; for 1.33333h; | 97% |
With dihydrogen peroxide In acetic acid for 12h; Ambient temperature; |
di-tert-butyl 4-<2-(tert-butoxycarbonyl)ethyl>-4-nitroheptanedicarboxylate
biotin
Biotinamidotris[2-(tert-butoxycarbonyl)ethyl]methane
Conditions | Yield |
---|---|
With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 13h; | 97% |
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