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Product Name: Metronidazole Synonyms: metronidazole Solution, 100ppm;Metronidazole solution ;METRONIDAZOLE BIOXTRA;2-Methyl-5-nitroimidazole-1-ethanol 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol;MNZ;skype:lila@tuskei.com;2-Met-h;2-Methyl-5-ni
Cas:443-48-1
Min.Order:100 Gram
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Type:Lab/Research institutions
inquiry1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE HangZhou Clake Biotech CO.,LTD is located in hangzhou city ,zhejiang province,China. We are engaged in export of APIs ,excipients,food additives and
Hubei Lidu New Materials Technology Co. , Ltd. is located in No. 12,3C Industrial Park, Zhongxiang Economic Development Zone, Hubei Province. The company is committed to fine chemical raw materials, pharmaceutical intermediates and other production,
As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:443-48-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiry443-48-1 Hubei Vanz Pharm Co. Ltd. is the manufacture of APIs, supplements raw powder and some customization products. located in Hubei province, China. We are one of the most professional company in pharm/chemical industry for more than 10 years.
Cas:443-48-1
Min.Order:1 Gram
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Type:Manufacturers
inquiryItems Standard Result Assay 98%min ----------------------------------------------------------------------------------------------
Cas:443-48-1
Min.Order:1 Gram
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inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:443-48-1
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inquiryUnique advantages for Metronidazole CAS 443-48-1 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or yellowish crystalline powder Storage:Store in 2-8℃ Package:25kg/
Cas:443-48-1
Min.Order:100 Kilogram
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inquiryXi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi
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Cas:443-48-1
Min.Order:1 Metric Ton
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inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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Cas:443-48-1
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Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:443-48-1
Min.Order:1 Kilogram
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Cas:443-48-1
Min.Order:1 Kilogram
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Name:Metronidazole CAS no:443-48-1 Grade:Anti anaerobic bacteria and anti Trichomonas Molecular formula:C6H9N3O3 Molecular weight:171.154 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability
Cas:443-48-1
Min.Order:25 Kilogram
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Type:Other
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:443-48-1
Min.Order:1 Gram
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Min.Order:1 Kilogram
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Type:Trading Company
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Min.Order:10 Kilogram
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Type:Trading Company
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Cas:443-48-1
Min.Order:1 Kilogram
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Type:Trading Company
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Cas:443-48-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryroduct Name: Metronidazole Other Name Flagyl CAS: 443-48-1 MF: C6H9N3O3
Cas:443-48-1
Min.Order:5 Metric Ton
FOB Price: $1.0 / 2.0
Type:Other
inquiryDear Friend, welcome you choose us ! And thank you very much for trust! We are one professional APIs and Chemicals supplier, we can provide you with good price and good service. Product Name Me
Cas:443-48-1
Min.Order:25 Kilogram
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Type:Other
inquiryAppearance:white to slightly yellow crystalline powder Storage:Room temperature Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in china
Cas:443-48-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed containers
Cas:443-48-1
Min.Order:100 Gram
Negotiable
Type:Other
inquiryConditions | Yield |
---|---|
With formic acid; sulfuric acid at 80℃; for 12h; Temperature; | 88% |
With formic acid at 50 - 60℃; for 0.5h; Reagent/catalyst; Temperature; | 74.9% |
With phosphoric acid; acetic anhydride In water at 25 - 30℃; for 2.5h; Yield given; | |
With sulfuric acid; acetic acid at 90℃; for 0.5h; Concentration; Temperature; Cooling; | |
With formic acid; sulfuric acid Large scale; |
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
benzoic acid
metronidazole
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; | 71% |
metronidazole phosphate
metronidazole
Conditions | Yield |
---|---|
With human serum In water at 37℃; human serum hydrolysis of metronidazole phosphate; pH dependence of solubility of metronidazole and metronidazole phosphate; |
Conditions | Yield |
---|---|
With aqueous buffer Rate constant; pHs 0.83-8.82, half-life times for the hydrolysis, also in simulated intestinal fluid (pH 7.55), Jones medium (pH 6.69) and Kupferberg medium (pH 6.11); |
Conditions | Yield |
---|---|
With aqueous buffer Rate constant; pHs 0.83-8.82, half-life times for the hydrolysis, also in simulated intestinal fluid (pH 7.55), Jones medium (pH 6.69) and Kupferberg medium (pH 6.11); |
Conditions | Yield |
---|---|
With aqueous buffer Rate constant; pHs 0.83-8.82, half-life times for the hydrolysis, also in simulated intestinal fluid (pH 7.55), Jones medium (pH 6.69) and Kupferberg medium (pH 6.11); |
metronidazole glycyl glycinate hydrochloride
A
Glycine anhydride
B
glycylglycine
C
metronidazole
Conditions | Yield |
---|---|
With aqueous buffer Rate constant; pHs 0.83-8.82, half-life times for the hydrolysis, also in simulated intestinal fluid (pH 7.55), Jones medium (pH 6.69) and Kupferberg medium (pH 6.11); |
metronidazole glycyl phenylalaninate hydrochloride
A
Gly-Phe-OH
B
metronidazole
C
cyclo(Gly-Phe)
Conditions | Yield |
---|---|
With aqueous buffer Rate constant; pHs 0.83-8.82, half-life times for the hydrolysis, also in simulated intestinal fluid (pH 7.55), Jones medium (pH 6.69) and Kupferberg medium (pH 6.11); |
Conditions | Yield |
---|---|
In water at 20℃; under 735.5 Torr; Rate constant; also in the presence of enzymes or cellular extracts with nitroreductase, oxygen reductase, superoxide dismutase or nitrite raductase activity, variation of pH; also the radical anion of 5-nitro-2-furaldoxime; | |
In water at 20℃; under 735.5 Torr; Rate constant; also in the presence of a copper oxidase (laccase or ceruloplasmin); also the radical anion of misonidazole; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
Conditions | Yield |
---|---|
With water at 37℃; Rate constant; rate constant of hydrolysis; | |
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
Conditions | Yield |
---|---|
With sodium chloride at 25℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers; | |
With water at 37℃; Rate constant; rate constant of hydrolysis; |
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
A
metronidazole
B
benzoic acid
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
2-Formyl-benzoic acid 2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl ester
A
metronidazole
B
o-carboxybenzaldehyde
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Mechanism; |
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
A
2,6-diformylbenzoic acid
B
metronidazole
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; |
A
2,6-diformylbenzoic acid
B
metronidazole
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
A
metronidazole
B
2-(2,2,2-trifluoroacetyl)benzoic acid
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; Thermodynamic data; var. temp., ΔH(excit.), ΔS)(excit.); |
Conditions | Yield |
---|---|
With hydroxide In 1,4-dioxane; water at 30℃; Rate constant; |
succinic acid bis-[2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl] ester
A
succinic acid
B
metronidazole
C
4-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethoxy]-4-oxobutanoic acid
Conditions | Yield |
---|---|
With phosphate buffer pH 7.4 In methanol; water at 37℃; Rate constant; var. pH, also in human plasma, Wistar rat liver homogenate; |
phthalic acid bis-[2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl] ester
A
benzene-1,2-dicarboxylic acid
B
metronidazole
C
1,2-benzenedicarboxylic acid, mono[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]ester
Conditions | Yield |
---|---|
With phosphate buffer pH 7.4 In methanol; water at 37℃; Rate constant; var. pH, also in human plasma, Wistar rat liver homogenate; |
Conditions | Yield |
---|---|
With phosphate buffer pH 7.4 In methanol; water at 37℃; for 48h; Rate constant; Kinetics; var. pH, also in human plasma, Wistar rat liver homogenate; |
Conditions | Yield |
---|---|
With phosphate buffer pH 7.4 In methanol; water at 37℃; Rate constant; Kinetics; var. pH, also in human plasma, Wistar rat liver homogenate; |
methanesulfonyl chloride
metronidazole
2-(5-nitro-2-methyl-1-imidazolyl)ethyl methanesulfonate
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0 - 20℃; | 100% |
With triethylamine In dichloromethane at 10 - 20℃; for 4h; | 97% |
With dmap; triethylamine In dichloromethane at 0 - 20℃; | 97.5% |
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at -10 - 20℃; | 99.1% |
metronidazole
1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole
Conditions | Yield |
---|---|
With thionyl chloride at 0 - 50℃; for 2h; | 99% |
With thionyl chloride In dichloromethane at 20℃; | 96% |
With thionyl chloride for 3h; Heating; | 90% |
Conditions | Yield |
---|---|
In methanol at 65℃; for 0.25h; | 99% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 99% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 99% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 99% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 99% |
nickel diacetate
metronidazole
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 99% |
metronidazole
Cysteamine
4-<(2-aminoethyl)thio>-2-methylimidazole-1-ethanol
Conditions | Yield |
---|---|
With pH 5.0 In water at 37℃; for 120h; | 98% |
With pH 5.0 at 37℃; for 120h; Product distribution; Mechanism; other reaction conditions; |
metronidazole
Conditions | Yield |
---|---|
With thionyl chloride In chloroform at 20℃; for 12h; | 98% |
With thionyl chloride In benzene for 2h; Heating; |
Conditions | Yield |
---|---|
In chloroform at 20℃; Product distribution / selectivity; | 98% |
In dichloromethane at 20℃; Product distribution / selectivity; | |
In N,N-dimethyl-formamide for 12h; | 7.32 g |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 98% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 98% |
Conditions | Yield |
---|---|
In methanol at 20 - 40℃; | 98% |
metronidazole
Conditions | Yield |
---|---|
With potassium fluoride; 1,3-bis(2,6-diisopropylphenyl)-2-fluoroimidazolium tetrafluoroborate In 1,4-dioxane at 40℃; for 17h; Inert atmosphere; Schlenk technique; Sealed tube; | 98% |
Stage #1: metronidazole With copper(l) chloride; diisopropyl-carbodiimide at 60℃; for 1h; Sealed tube; Microwave irradiation; Stage #2: With copper (II)-fluoride In water at 100℃; for 24h; Microwave irradiation; | 61% |
benzoyl chloride
metronidazole
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
Conditions | Yield |
---|---|
With dmap; ammonium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In chloroform at 5℃; for 3h; pH=9; Reagent/catalyst; Temperature; Solvent; pH-value; | 97.38% |
With pyridine In dichloromethane at 20℃; | 85.12% |
With triethylamine In 1,4-dioxane; chloroform 1.) r.t., 30 min, 2.) reflux, 4 h; |
succinic acid anhydride
metronidazole
4-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethoxy]-4-oxobutanoic acid
Conditions | Yield |
---|---|
With dmap In acetonitrile for 48h; Ambient temperature; | 95% |
With pyridine at 20℃; for 24h; Inert atmosphere; Cooling with ice; | 95% |
With sodium hydroxide In methanol; water at 60℃; for 2h; | 94% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In chloroform at 20℃; | 95% |
With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane for 4h; Esterification; | 72% |
potassium tetrachloroplatinate(II)
metronidazole
cis-Pt(metronidazole)2Br2
Conditions | Yield |
---|---|
With KBr In water 20-fold excess of KBr added to aq. soln. of K2(PtCl4), added solid ligand, stirred at 50 °C for 1 h; ppt. filtered, washed with EtOH/Et2O, Et2O, dried in vac.; elem. anal.; | 95% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In chloroform at 20℃; | 95% |
metronidazole
Conditions | Yield |
---|---|
Stage #1: metronidazole With potassium hexamethylsilazane In tetrahydrofuran; N,N-dimethyl-formamide at 25℃; for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: 4-cyano-N,N,N-trimethylanilinium trifluoromethansulfonate In tetrahydrofuran; N,N-dimethyl-formamide at 25℃; for 3h; Inert atmosphere; Schlenk technique; | 95% |
metronidazole
Conditions | Yield |
---|---|
In benzene byproducts: pyridine; soln. of metronidazole (excess) and Pd compd. in benzene stirred for ca. 12 h at ca. 25 °C; evapn. in vac.; residue chromd. (TLC) on silica gel eluting with ethyl acetate; | 94.8% |
p-toluenesulfonyl chloride
metronidazole
toluene-4-sulfonic acid 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 5h; | 94% |
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 3h; | 90% |
With pyridine | 85% |
(9R,12Z )-9-hydroxyoctadec-12-enoic acid
metronidazole
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In chloroform at 20℃; | 92% |
Conditions | Yield |
---|---|
With potassium iodide In ethanol; water aq. soln. of KI was added to a soln. of Pt-complex in H2O, stirred for 1 min at room temp., a soln. of ligand in EtOH was added, stirred for 30min, stored at ca. 2°C overnight; elem. anal.; | 91% |
potassium tetrachloroplatinate(II)
metronidazole
cis-Pt(metronidazole)2Cl2
Conditions | Yield |
---|---|
In water 50°C, 1 h (crystn.); recrystn. (Me2CO/H2O); | 91% |
In water solid ligand added to aq. soln. of K2(PtCl4), stirred at 50 °C for 1 h; ppt. filtered, washed with EtOH/Et2O, Et2O, dried in vac.; elem. anal.; | 90% |
Conditions | Yield |
---|---|
With carbon tetrabromide; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 1.75h; | 91% |
With carbon tetrabromide; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 1.75h; | 91% |
With sulfuric acid; ammonium bromide In water at 120℃; for 12h; | 87.6% |
Stage #1: metronidazole With bromine; phosphorus trichloride In ethyl acetate for 3h; Reflux; Stage #2: With sodium hydroxide pH=5 - 6; |
metronidazole
m-Toluic acid
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-methylbenzoate
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; | 91% |
phthalic anhydride
metronidazole
1,2-benzenedicarboxylic acid, mono[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]ester
Conditions | Yield |
---|---|
With dmap In acetonitrile Ambient temperature; | 90% |
With dmap In acetonitrile at 20℃; | 87.1% |
With dmap In acetonitrile at 20℃; | 87.1% |
With dmap In acetonitrile |
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