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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-Hydroxyisophthalonitrile Manufacturer/High quality/Best price/In stock

Cas:79370-78-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Hydroxy-Isophthalonitrile supplier in China

Cas:79370-78-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Hydroxy-Isophthalonitrile

Cas:79370-78-8

Min.Order:1

Negotiable

Type:Other

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 79370-78-8 with competitive price

Cas:79370-78-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,3-Benzenedicarbonitrile,5-hydroxy- 79370-78-8

Cas:79370-78-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Benzenedicarbonitrile,5-hydroxy-

Cas:79370-78-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,3-Benzenedicarbonitrile,5-hydroxy-

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

5-HYDROXY-ISOPHTHALONITRILE 79370-78-8

Cas:79370-78-8

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-HYDROXY-ISOPHTHALONITRILE 79370-78-8

Cas:79370-78-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,3-Benzenedicarbonitrile,5-hydroxy-

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 5-HYDROXY-ISOPHTHALONITRILE Synonyms: 1,3-BENZENEDICARBONITRILE, 5-HYDROXY-;5-HYDROXY-ISOPHTHALONITRILE;3,5-Dicyanohydroxybenzene;5-hydroxy-1,3-Benzenedicarbonitrile;5-hydroxybenzene-1,3-dicarbonitrile CAS: 79370-78-8 MF: C8H4N2

TIANFU-CHEM 79370-78-8 5-HYDROXY-ISOPHTHALONITRILE

Cas:79370-78-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

5-Hydroxy-isophthalonitrile

Cas:79370-78-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

79370-78-8 CAS NO.79370-78-8

Cas:79370-78-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

1,3-Benzenedicarbonitrile,5-hydroxy-

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Other

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Hydroxybenzene-1,3-Dicarbonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

5-Hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

5-Hydroxy-isophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

5-Hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 5-Hydroxyisophthalonitrile 10g

Cas:79370-78-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

5-Hydroxy-Isophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

5-Hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1,3-Benzenedicarbonitrile,5-hydroxy-

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

5-Hydroxy-Isophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

5-Hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

5-HYDROXY-ISOPHTHALONITRILE CAS No.79370-78-8

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

79370-78-8

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

5-Hydroxyisophthalonitrile cas 79370-78-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Hydroxyisophthalonitrile cas 79370-78-8

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

5-Hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-HYDROXY-ISOPHTHALONITRILE

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

79370-78-8 Application:intermediate

5-hydroxyisophthalonitrile

Cas:79370-78-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-hydroxy-benzene-1,3-dicarbonylamide
68052-43-7

5-hydroxy-benzene-1,3-dicarbonylamide

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
With trichlorophosphate In acetonitrile96%
With trichlorophosphate In N,N-dimethyl-formamide at 0 - 45℃; for 4h; Schlenk technique; Cooling with ice;74%
at 345℃; for 1h; Temperature;
With phosphorus pentoxide under 15.0015 - 37.5038 Torr; for 1h; Temperature; Heating;
4-nitro-phenol
100-02-7

4-nitro-phenol

5-nitrobenzene-1,3-dicarbonitrile
33224-18-9

5-nitrobenzene-1,3-dicarbonitrile

A

bis(4-nitrophenyl)ether
101-63-3

bis(4-nitrophenyl)ether

B

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

C

3,3',5,5'-tetracyanodiphenyl ether

3,3',5,5'-tetracyanodiphenyl ether

D

5-(4-Nitro-phenoxy)-isophthalonitrile
188998-65-4

5-(4-Nitro-phenoxy)-isophthalonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 2.3h;A n/a
B n/a
C n/a
D 25%
4-nitro-phenol
100-02-7

4-nitro-phenol

5-(4-Nitro-phenoxy)-isophthalonitrile
188998-65-4

5-(4-Nitro-phenoxy)-isophthalonitrile

A

bis(4-nitrophenyl)ether
101-63-3

bis(4-nitrophenyl)ether

B

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
With potassium carbonate at 120℃; for 7h;
5-nitrobenzene-1,3-dicarbonitrile
33224-18-9

5-nitrobenzene-1,3-dicarbonitrile

4-nitrophenol sodium salt
824-78-2

4-nitrophenol sodium salt

A

bis(4-nitrophenyl)ether
101-63-3

bis(4-nitrophenyl)ether

B

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

C

5-(4-Nitro-phenoxy)-isophthalonitrile
188998-65-4

5-(4-Nitro-phenoxy)-isophthalonitrile

Conditions
ConditionsYield
Product distribution; various temperatures;
4-cyanophenol
767-00-0

4-cyanophenol

5-(4-Cyano-phenoxy)-isophthalonitrile
188998-64-3

5-(4-Cyano-phenoxy)-isophthalonitrile

A

4-(4'-cyanophenoxy)benzonitrile
6508-04-9

4-(4'-cyanophenoxy)benzonitrile

B

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 150℃;
5-nitro-1,3-benzenedicarbonylchloride
13438-30-7

5-nitro-1,3-benzenedicarbonylchloride

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 76 percent
2: K2CO3 / dimethylformamide / 2.3 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1: 76 percent
2: 25 percent / K2CO3 / dimethylformamide / 2.3 h / 100 °C
3: K2CO3 / 7 h / 120 °C
View Scheme
Multi-step reaction with 3 steps
1: 76 percent
2: 70 percent / K2CO3 / dimethylformamide / 3 h / 100 °C
3: K2CO3 / dimethylformamide / 150 °C
View Scheme
5-nitrobenzene-1,3-dicarboxylic acid
618-88-2

5-nitrobenzene-1,3-dicarboxylic acid

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Cl-X
2: 76 percent
3: K2CO3 / dimethylformamide / 2.3 h / 100 °C
View Scheme
Multi-step reaction with 4 steps
1: Cl-X
2: 76 percent
3: 25 percent / K2CO3 / dimethylformamide / 2.3 h / 100 °C
4: K2CO3 / 7 h / 120 °C
View Scheme
Multi-step reaction with 4 steps
1: Cl-X
2: 76 percent
3: 70 percent / K2CO3 / dimethylformamide / 3 h / 100 °C
4: K2CO3 / dimethylformamide / 150 °C
View Scheme
5-nitrobenzene-1,3-dicarbonitrile
33224-18-9

5-nitrobenzene-1,3-dicarbonitrile

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 25 percent / K2CO3 / dimethylformamide / 2.3 h / 100 °C
2: K2CO3 / 7 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1: 70 percent / K2CO3 / dimethylformamide / 3 h / 100 °C
2: K2CO3 / dimethylformamide / 150 °C
View Scheme
5-methoxyisophthalonitrile
453565-53-2

5-methoxyisophthalonitrile

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Stage #1: 5-methoxyisophthalonitrile With aluminum (III) chloride In dichloromethane at 0 - 45℃; for 144h;
Stage #2: With hydrogenchloride In dichloromethane; water at 20℃; for 0.166667h;
Stage #1: 5-methoxyisophthalonitrile With aluminum (III) chloride In dichloromethane at 0 - 45℃; for 144h;
Stage #2: With hydrogenchloride In water at 20℃; for 0.166667h;
Stage #1: 5-methoxyisophthalonitrile With aluminum (III) chloride In dichloromethane at 0 - 45℃; for 144h;
Stage #2: With hydrogenchloride In water at 20℃; for 0.166667h;
5-Hydroxyisophthalic acid
618-83-7

5-Hydroxyisophthalic acid

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride / tetrahydrofuran; N,N-dimethyl-formamide / Schlenk technique; Reflux
2: ammonium hydroxide / tetrahydrofuran / -40 °C
3: trichlorophosphate / N,N-dimethyl-formamide / 4 h / 0 - 45 °C / Schlenk technique; Cooling with ice
View Scheme
Multi-step reaction with 2 steps
1: ammonium / 0.5 h / Heating
2: phosphorus pentoxide / 1 h / 15 - 37.5 Torr / Heating
View Scheme
5-Hydroxybenzene-1,3-dicarbonyl dichloride
61842-44-2

5-Hydroxybenzene-1,3-dicarbonyl dichloride

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonium hydroxide / tetrahydrofuran / -40 °C
2: trichlorophosphate / N,N-dimethyl-formamide / 4 h / 0 - 45 °C / Schlenk technique; Cooling with ice
View Scheme
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

<2H9>trimethylsulphoxonium iodide
23726-00-3

<2H9>trimethylsulphoxonium iodide

5-(methoxy-d3)isophthalonitrile

5-(methoxy-d3)isophthalonitrile

Conditions
ConditionsYield
With potassium carbonate at 65℃; for 18h; Sealed tube;99%
ethyl (2,3-difluoro-4-nitrophenyl)acetate
317356-84-6

ethyl (2,3-difluoro-4-nitrophenyl)acetate

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

C18H12FN3O5
867366-79-8

C18H12FN3O5

Conditions
ConditionsYield
Stage #1: 5-hydroxyisophthalonitrile With sodium t-butanolate In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: ethyl (2,3-difluoro-4-nitrophenyl)acetate In tetrahydrofuran for 3h;
Stage #3: With hydrogenchloride; water In tetrahydrofuran
78%
(2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester
234108-73-7

(2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

C18H16N4O3

C18H16N4O3

Conditions
ConditionsYield
With C45H65FeNO3P2PdS; caesium carbonate In toluene at 100℃; for 24h; Inert atmosphere; Sealed tube;76%
sodium tetrahydroborate
16940-66-2

sodium tetrahydroborate

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

sodium-tetrakis(bis-3,5-cyano-phenoxy)-borate

sodium-tetrakis(bis-3,5-cyano-phenoxy)-borate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 3h; Reflux;63%
4-chloro-3,5-heptanedione
13054-81-4

4-chloro-3,5-heptanedione

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

5-(2-oxo-1-propanoylbutoxy)isophthalonitrile
473924-01-5

5-(2-oxo-1-propanoylbutoxy)isophthalonitrile

Conditions
ConditionsYield
With caesium carbonate In acetone47%
With triethylamine In Isopropyl acetate Reflux;
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

tert-butyl 4-bromobutyrate
110661-91-1

tert-butyl 4-bromobutyrate

tert-butyl 4-(3,5-dicyanophenoxy)butanoate

tert-butyl 4-(3,5-dicyanophenoxy)butanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 16h;42%
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

3-chloropentane-2,4-dione
1694-29-7

3-chloropentane-2,4-dione

5-[(3, 5-dimethyl-1H-pyrazol-4-yl)oxy]-5-isophthalonitrile
676994-55-1

5-[(3, 5-dimethyl-1H-pyrazol-4-yl)oxy]-5-isophthalonitrile

Conditions
ConditionsYield
Stage #1: 5-hydroxyisophthalonitrile; 3-chloropentane-2,4-dione With cesium carbonate In acetone at 65℃; for 2h;
Stage #2: With hydrogenchloride In water; acetone at 20℃;
Stage #3: With acetic acid; hydrazine at 20℃; for 0.166667h;
Stage #1: 5-hydroxyisophthalonitrile; 3-chloropentane-2,4-dione With caesium carbonate at 65℃; for 2h;
Stage #2: With acetic acid; hydrazine at 20℃; for 0.166667h;
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

methyl 2-chloro-3-oxopentanoate
114192-09-5

methyl 2-chloro-3-oxopentanoate

2-(3,5-dicyano-phenoxy)-3-oxo-pentanoic acid methyl ester

2-(3,5-dicyano-phenoxy)-3-oxo-pentanoic acid methyl ester

Conditions
ConditionsYield
With caesium carbonate In acetone at 20℃; for 2.75h; Heating / reflux;
(4E)-1-(benzyloxy)-4-chloro-5-hydroxy-4-hepten-3-one
473924-09-3

(4E)-1-(benzyloxy)-4-chloro-5-hydroxy-4-hepten-3-one

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

5-({(1E)-1-[3-(benzyloxy)propanoyl]-2-hydroxy-1-butenyl}oxy)isophthalonitrile
473924-11-7

5-({(1E)-1-[3-(benzyloxy)propanoyl]-2-hydroxy-1-butenyl}oxy)isophthalonitrile

Conditions
ConditionsYield
With caesium carbonate In acetone at 20℃; for 2h; Heating / reflux;
With caesium carbonate In acetone for 2h; Heating / reflux;
2-chloro-1-cyclopropylbutane-1,3-dione
473924-31-1

2-chloro-1-cyclopropylbutane-1,3-dione

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

5-[1-(cyclopropylcarbonyl)-2-oxopropoxy]isophtalonitrile
675198-31-9

5-[1-(cyclopropylcarbonyl)-2-oxopropoxy]isophtalonitrile

Conditions
ConditionsYield
With caesium carbonate In acetone at 60℃; for 3h;
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

5-(4-methylthiopyrimidin-2-yloxy)isophthalonitrile
548466-06-4

5-(4-methylthiopyrimidin-2-yloxy)isophthalonitrile

Conditions
ConditionsYield
With potassium carbonate In water; ethyl acetate; N,N-dimethyl-formamide
2,4-bis(3-chloro-4-cyanophenoxy)pyrimidine
548466-09-7

2,4-bis(3-chloro-4-cyanophenoxy)pyrimidine

5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

5-[2-(3-chloro-4-cyanophenoxy)pyrimidin-4-yloxy]isophthalonitrile
548466-02-0

5-[2-(3-chloro-4-cyanophenoxy)pyrimidin-4-yloxy]isophthalonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

N,N-Dimethylthiocarbamoyl chloride
16420-13-6

N,N-Dimethylthiocarbamoyl chloride

O-(3,5-dicyanophenyl)dimethylthiocarbamate
868525-05-7

O-(3,5-dicyanophenyl)dimethylthiocarbamate

Conditions
ConditionsYield
Stage #1: 5-hydroxyisophthalonitrile With sodium carbonate In 1-methyl-pyrrolidin-2-one at 0 - 20℃; for 0.5h;
Stage #2: N,N-Dimethylthiocarbamoyl chloride In 1-methyl-pyrrolidin-2-one at 20 - 70℃; for 16.5h;
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

4-(3,5-dicyanophenoxy)butanoic acid

4-(3,5-dicyanophenoxy)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 90 °C
2: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C
View Scheme
5-hydroxyisophthalonitrile
79370-78-8

5-hydroxyisophthalonitrile

4-(3,5-dicyanophenoxy)-N-(5-methylthiazol-2-yl)butanamide

4-(3,5-dicyanophenoxy)-N-(5-methylthiazol-2-yl)butanamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 90 °C
2: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C
3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 1,2-dichloro-ethane / 16 h / 45 °C
View Scheme

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