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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

4-Cyclopropyl-1-naphthalenamine

Cas:878671-94-4

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 878671-94-4 with competitive price

Cas:878671-94-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

LESINURAD Intermediate 878671-94-4 API Manufacturer

Cas:878671-94-4

Min.Order:10 Gram

Negotiable

Type:Other

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 1-Naphthalenamine, 4-cyclopropyl- Synonyms: 1-Naphthalenamine, 4-cyclopropyl-;4-Cyclopropyl-1-Naphthalenamine;4-Cyclopropylnaphthalen-1-aMine;4-Cyclopropyl-1-naphthalenaMine oxalate;1-phthalemine, 4-cyclopropyl-;1-amino-4-cycloprop

1-Naphthalenamine, 4-cyclopropyl- high purity best quality

Cas:878671-94-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

CAS NO.878671-94-4 Hot sale 4-cyclopropylnaphthalen-1-amine 97% min

Cas:878671-94-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-CYCLOPROPYLNAPHTHALEN-1-AMINE

Cas:878671-94-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-cyclopropylnaphthalen-1-amine

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Naphthalenamine, 4-cyclopropyl-

Cas:878671-94-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

CAS NO.878671-94-4 Hot sale 4-cyclopropylnaphthalen-1-amine 97% min

Cas:878671-94-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

1-Naphthalenamine, 4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1-Naphthalenamine, 4-cyclopropyl-

Cas:878671-94-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

CAS NO.878671-94-4 Hot sale 4-cyclopropylnaphthalen-1-amine 97% min

Cas:878671-94-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

CAS NO.878671-94-4 Hot sale 4-cyclopropylnaphthalen-1-amine 97% min

Cas:878671-94-4

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 1-Amino-4-(cyclopropyl)naphthalene(878671-94-4)

Cas:878671-94-4

Min.Order:100 Gram

Negotiable

Type:Other

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

4-Cyclopropylnaphthalen-1-amine

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

CAS NO.878671-94-4 Hot sale 4-cyclopropylnaphthalen-1-amine 97% min

Cas:878671-94-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Hohance Chemical Co., ltd

1)Entity factory, can batch production 2)Sample service 3)the most competitive price with good quality: we do this products so many years with Skilled craft can control the cost. so we can provide the most competitive price for our cust

4-Cyclopropyl-1-Naphthalenamine

Cas:878671-94-4

Min.Order:1 Metric Ton

FOB Price: $22.0 / 33.0

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

4-cyclopropylnaphthalen-1-amine

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

4-Cyclopropyl-1-Naphthalenamine

Cas:878671-94-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

4-Cyclopropylnaphthalen-1-amine

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

1-Naphthalenamine, 4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Trading Company

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Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

1-Naphthalenamine,4-cyclopropyl-

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

≥99.0% Appearance:White or off-white powder Storage:Room temperature preservation Package:Packaging according to customer requirements Application:used for medicine Transportation:by sea by air express Port:china port

4-Cyclopropyl-naphthalen-1-ylamine for Lesinurad Intermediate 01

Cas:878671-94-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

1-NaphthalenaMine, 4-cyclopropyl- CAS No.878671-94-4

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

878671-94-4

Cas:878671-94-4

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

1-cyclopropyl-4-nitronaphthalene
878671-93-3

1-cyclopropyl-4-nitronaphthalene

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
Stage #1: 1-cyclopropyl-4-nitronaphthalene With iron hydroxide oxide In water at 80℃; for 0.5h;
Stage #2: With hydrazine In water for 2h; Solvent; Temperature; Reagent/catalyst; Time;
96%
With ammonium chloride; zinc In tetrahydrofuran; water for 10h; Reflux;89.1%
With ammonium chloride; zinc In tetrahydrofuran; water Reagent/catalyst; Reflux;87%
4-Bromo-1-naphthylamine
2298-07-9

4-Bromo-1-naphthylamine

cyclopropylboronic acid
411235-57-9

cyclopropylboronic acid

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In water; toluene at 90℃; for 6h; Suzuki Coupling; Inert atmosphere;95.3%
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 90℃; for 6h; Inert atmosphere;95.3%
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In water; toluene at 100℃; for 12h; Inert atmosphere;83.6%
1-bromo-4-cyclopropylnaphthalene
127971-24-8

1-bromo-4-cyclopropylnaphthalene

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
With copper(I) oxide; ammonium hydroxide In N,N-dimethyl-formamide at 100℃; for 28h; Solvent; Reagent/catalyst; Temperature; Autoclave; Green chemistry;80%
1-cyclopropyl-naphthalene
25033-19-6

1-cyclopropyl-naphthalene

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium nitrite / 2.5 h / 0 °C
2: hydrogen / palladium 10% on activated carbon / ethanol
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 0 - 20 °C
2: palladium on activated charcoal; hydrogen
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / water; dichloromethane
2: palladium on activated charcoal; hydrogen; oxalic acid / ethanol
View Scheme
Multi-step reaction with 2 steps
1: nitric acid
2: iron perchlorate hexahydrate; hydrazine hydrate / ethanol / Reflux
View Scheme
Multi-step reaction with 2 steps
1: acetic acid; nitric acid / 7 h / 20 °C / Cooling with ice
2: zinc; ammonium chloride / tetrahydrofuran; water / 10 h / Reflux
View Scheme
1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 0 - 20 °C
2: sodium nitrite / 2.5 h / 0 °C
3: hydrogen / palladium 10% on activated carbon / ethanol
View Scheme
Multi-step reaction with 3 steps
1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 0 - 5 °C
2: nitric acid / 0 - 20 °C
3: palladium on activated charcoal; hydrogen
View Scheme
Multi-step reaction with 3 steps
1.1: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / Cooling with ice
1.2: 44 h / 20 °C / Reflux; Inert atmosphere
2.1: acetic acid; nitric acid / 7 h / 20 °C / Cooling with ice
3.1: zinc; ammonium chloride / tetrahydrofuran; water / 10 h / Reflux
View Scheme
1-amino-naphthalene
134-32-7

1-amino-naphthalene

cyclopropylboronic acid
411235-57-9

cyclopropylboronic acid

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); phosphoric acid In water; toluene at 100℃; for 12h; Inert atmosphere;
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

phenyl chloroformate
1885-14-9

phenyl chloroformate

C20H17NO2

C20H17NO2

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at -10℃; for 1h; Temperature; Inert atmosphere;98.5%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

1,1'-Thiocarbonyldiimidazole
6160-65-2

1,1'-Thiocarbonyldiimidazole

(1-cyclopropylnaphthalen-4-yl)isothiocyanate
878671-95-5

(1-cyclopropylnaphthalen-4-yl)isothiocyanate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 12h;96.2%
In dichloromethane at 20℃; for 1h;80%
In dichloromethane at 20℃;
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

2-nitro-3-(trifluoromethylsulfonyloxy)pyridine
146336-72-3

2-nitro-3-(trifluoromethylsulfonyloxy)pyridine

N-(4-cyclopropylnaphthalen-1-yl)-2-nitropyridin-3-amine

N-(4-cyclopropylnaphthalen-1-yl)-2-nitropyridin-3-amine

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In toluene at 90℃; for 36h; Inert atmosphere;95.3%
With 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate In toluene at 90℃; for 36h; Inert atmosphere;33.3%
carbon disulfide
75-15-0

carbon disulfide

1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

(1-cyclopropylnaphthalen-4-yl)isothiocyanate
878671-95-5

(1-cyclopropylnaphthalen-4-yl)isothiocyanate

Conditions
ConditionsYield
Stage #1: carbon disulfide; 1-amino-4-cyclopropylnaphthalene With potassium carbonate In water; N,N-dimethyl-formamide at 15℃; for 3.5h;
Stage #2: With 1,3,5-trichloro-2,4,6-triazine In dichloromethane; water; N,N-dimethyl-formamide at 0℃; for 1h;
Stage #3: With water; sodium hydroxide In dichloromethane; N,N-dimethyl-formamide for 2h;
94%
Stage #1: 1-amino-4-cyclopropylnaphthalene With 1,4-diaza-bicyclo[2.2.2]octane In toluene at 20℃;
Stage #2: carbon disulfide In toluene at 20℃; for 7.5h;
Stage #3: With p-toluenesulfonyl chloride In toluene at 0℃; for 3h; Reflux;
86.3%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

thiophosgene
463-71-8

thiophosgene

(1-cyclopropylnaphthalen-4-yl)isothiocyanate
878671-95-5

(1-cyclopropylnaphthalen-4-yl)isothiocyanate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.0833333h;86%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.0833333h;86%
Stage #1: 1-amino-4-cyclopropylnaphthalene; thiophosgene With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.0833333h;
Stage #2: With hydrogenchloride In dichloromethane; water
86%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

C8H15N3O

C8H15N3O

3-(3-buten-1-yl)-4-(4-cyclopropylnaphth-1-yl)-4H-1,2,4-triazole

3-(3-buten-1-yl)-4-(4-cyclopropylnaphth-1-yl)-4H-1,2,4-triazole

Conditions
ConditionsYield
With acetic acid In acetonitrile at 120℃; Inert atmosphere;81%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

4-Pentenoic acid hydrazide
86538-23-0

4-Pentenoic acid hydrazide

3-(3-buten-1-yl)-4-(4-cyclopropylnaphth-1-yl)-4H-1,2,4-triazole

3-(3-buten-1-yl)-4-(4-cyclopropylnaphth-1-yl)-4H-1,2,4-triazole

Conditions
ConditionsYield
Stage #1: 4-Pentenoic acid hydrazide With N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 50℃; for 2h;
Stage #2: 1-amino-4-cyclopropylnaphthalene With acetic acid for 12h; Reflux;
78%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

diazodimedone
1807-68-7

diazodimedone

4-cyclopropyl-9,9-dimethyl-9,10-dihydro-7H-benzo[kl]acridin-11(8H)-one

4-cyclopropyl-9,9-dimethyl-9,10-dihydro-7H-benzo[kl]acridin-11(8H)-one

Conditions
ConditionsYield
With {Ir(η5-C5Me5)(CH3CN)3}{SbF6}2; acetic acid In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere; Schlenk technique; Sealed tube; regioselective reaction;78%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

diformylhydrazine
628-36-4

diformylhydrazine

4-(4-cyclopropylnaphthalene)-1,2,4-triazole

4-(4-cyclopropylnaphthalene)-1,2,4-triazole

Conditions
ConditionsYield
With pyridine; chloro-trimethyl-silane In toluene at 20℃; for 2h; Solvent; Reagent/catalyst; Temperature; Reflux;78%
With pyridine; chloro-trimethyl-silane at 20℃; for 2h; Reflux;70%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

C13H12ClN

C13H12ClN

Conditions
ConditionsYield
With N-chloro-succinimide; acetic acid at 20℃; for 16h;64.47%
With N-chloro-succinimide; acetic acid at 20℃; for 16h;64.47%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

3-chloro-2-nitropyridine
54231-32-2

3-chloro-2-nitropyridine

N-(4-cyclopropylnaphthalen-1-yl)-2-nitropyridin-3-amine

N-(4-cyclopropylnaphthalen-1-yl)-2-nitropyridin-3-amine

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 20 - 90℃; for 12.25h; Inert atmosphere;60.6%
With palladium acetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 90℃; for 12h; Buchwald-Hartwig Coupling; Inert atmosphere;60.6%
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol
878671-96-6

5-amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 0 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 15 h / 50 °C
2.2: 60 h / 50 °C
View Scheme
Multi-step reaction with 2 steps
1: dichloromethane / 12 h / 20 °C
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 50 °C
View Scheme
Multi-step reaction with 2 steps
1: dichloromethane / 20 °C
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 50 h
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

2-((5-amino-4-(4-cyclopropyl-naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid methyl ester

2-((5-amino-4-(4-cyclopropyl-naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 0 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 15 h / 50 °C
2.2: 60 h / 50 °C
3.1: potassium carbonate / 24.08 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
3: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
4: N,N-dimethyl-formamide / 14 - 22 °C
View Scheme
Multi-step reaction with 5 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide
4: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
5: N,N-dimethyl-formamide / 14 - 22 °C
View Scheme
Multi-step reaction with 3 steps
1: dichloromethane / 12 h / 20 °C
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 50 °C
3: potassium carbonate / N,N-dimethyl-formamide / 24 h / 50 °C
View Scheme
Multi-step reaction with 3 steps
1: dichloromethane / 20 °C
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 50 h
3: potassium carbonate / N,N-dimethyl-formamide / 20 °C
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 0 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 15 h / 50 °C
2.2: 60 h / 50 °C
3.1: potassium carbonate / 24.08 h / 20 °C
4.1: sodium nitrite; N-benzyl-N,N,N-triethylammonium chloride; Bromoform; dichloro-acetic acid / 3 h / 20 °C
5.1: water; lithium hydroxide / ethanol; tetrahydrofuran / 0.83 h / 0 °C
5.2: 0 °C / pH 7
View Scheme
Multi-step reaction with 6 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
5: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
6: sodium hydroxide; water / toluene / 18 - 25 °C
View Scheme
Multi-step reaction with 6 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
3: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
4: N,N-dimethyl-formamide / 14 - 22 °C
5: copper(ll) bromide; potassium nitrite / acetonitrile / 14 - 20 °C
6: sodium hydroxide; water / toluene / 18 - 25 °C
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid methyl ester

2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 0 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 15 h / 50 °C
2.2: 60 h / 50 °C
3.1: potassium carbonate / 24.08 h / 20 °C
4.1: sodium nitrite; N-benzyl-N,N,N-triethylammonium chloride; Bromoform; dichloro-acetic acid / 3 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
5: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
View Scheme
Multi-step reaction with 5 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
3: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
4: N,N-dimethyl-formamide / 14 - 22 °C
5: copper(ll) bromide; potassium nitrite / acetonitrile / 14 - 20 °C
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid sodium salt
1151516-14-1

2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid sodium salt

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 0 °C
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 15 h / 50 °C
2.2: 60 h / 50 °C
3.1: potassium carbonate / 24.08 h / 20 °C
4.1: sodium nitrite; N-benzyl-N,N,N-triethylammonium chloride; Bromoform; dichloro-acetic acid / 3 h / 20 °C
5.1: water; lithium hydroxide / ethanol; tetrahydrofuran / 0.83 h / 0 °C
5.2: 0 °C / pH 7
6.1: sodium hydroxide / ethanol; water / 0.25 h / 10 °C
View Scheme
Multi-step reaction with 6 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: sodium carbonate / N,N-dimethyl-formamide / 27 - 35 °C / Large scale
5: N-Bromosuccinimide / tetrahydrofuran / 27 - 32 °C / Large scale
6: sodium hydroxide / toluene; water / 18 - 25 °C / Large scale
View Scheme
Multi-step reaction with 6 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
3: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
4: N,N-dimethyl-formamide / 14 - 22 °C
5: copper(ll) bromide; potassium nitrite / acetonitrile / 14 - 20 °C
6: sodium hydroxide / toluene; water / 18 - 25 °C / Large scale
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Reaxys ID: 26486083

Reaxys ID: 26486083

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: N,N-dimethyl-formamide
5: N-Bromosuccinimide / tetrahydrofuran
View Scheme
Multi-step reaction with 6 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
5: N,N-dimethyl-formamide
6: N-Bromosuccinimide / tetrahydrofuran
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

3-amino-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione
878671-96-6

3-amino-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
3: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
View Scheme
Multi-step reaction with 4 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide
4: sodium hydroxide / N,N-dimethyl-formamide; water / Heating
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

Reaxys ID: 26486087

Reaxys ID: 26486087

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
3: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
4: N,N-dimethyl-formamide
View Scheme
Multi-step reaction with 5 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide / 50 - 55 °C
4: potassium hydrogencarbonate / N,N-dimethyl-formamide; water / 90 - 140 °C
5: N,N-dimethyl-formamide
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

(1-cyclopropylnaphthalen-4-yl)isothiocyanate
878671-95-5

(1-cyclopropylnaphthalen-4-yl)isothiocyanate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene; water
2: potassium hydroxide
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

C15H17N5S*ClH
1533519-90-2

C15H17N5S*ClH

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide
View Scheme
Multi-step reaction with 3 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide
View Scheme
1-amino-4-cyclopropylnaphthalene
878671-94-4

1-amino-4-cyclopropylnaphthalene

N-(4-cyclopropylnaphthalen-1-yl)-2-formylhydrazine-1-thiocarboxamide
1533519-86-6

N-(4-cyclopropylnaphthalen-1-yl)-2-formylhydrazine-1-thiocarboxamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; 5,5-dimethyl-1,3-cyclohexadiene / 90 - 140 °C
2: N,N-dimethyl-formamide / 50 - 55 °C
View Scheme
Multi-step reaction with 3 steps
1: toluene; water
2: potassium hydroxide
3: N,N-dimethyl-formamide / 50 - 55 °C
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / water; N,N-dimethyl-formamide / 3.5 h / 15 °C
1.2: 1 h / 0 °C
1.3: 2 h
2.1: ethyl acetate / 2 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: ethyl acetate
2: ethanol
View Scheme

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