As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:926922-18-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:926922-18-1
Min.Order:1 Kilogram
FOB Price: $2.0 / 10.0
Type:Trading Company
inquiry3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide CAS:926922-18-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of
Cas:926922-18-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:926922-18-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAppearance:Off white to slight yellow solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common pro
Cas:926922-18-1
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:926922-18-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryN-(3-(TRIFLUOROMETHYL)-5-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL)-3-IODO-4-METHYLBENZAMIDEAppearance:detailed see specifications Storage:Keep away of light, cool place Package:25kg/drum;200kg/drum Application:An important raw material and intermediate used
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryN-(3-(Trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl)-3-iodo-4-methylbenzamide Application:Organic Chemicals
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGood Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryPrice, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryHuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of
Cas:926922-18-1
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
Type:Trading Company
inquiryJoyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryFINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide,
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryn-(3-(trifluoromethyl)-5-(4-methyl-1h-imidazol-1-yl)phenyl)-3-iodo-4-methylbenzamide Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,B
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Trading Company
inquiryCas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryCas:926922-18-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryR & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
N-(3-(trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl)-3-iodo-4-methylbenzamide
Cas:926922-18-1
Min.Order:0
Negotiable
Type:Trading Company
inquiry3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
3-iodo-4-methylbenzoyl chloride
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Stage #1: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline; 3-iodo-4-methylbenzoyl chloride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; Stage #2: With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran | 85% |
With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h; | 4.60 g |
With N-ethyl-N,N-diisopropylamine; dmap In tetrahydrofuran at 20℃; for 2h; |
3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
3-iodo-4-toluic acid
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; thionyl chloride; water | 84.3% |
Stage #1: 3-iodo-4-toluic acid With thionyl chloride for 6h; Stage #2: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline With N-ethyl-N,N-diisopropylamine In chloroform at 60℃; for 5h; | 57% |
Stage #1: 3-iodo-4-toluic acid With thionyl chloride for 1h; Reflux; Stage #2: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline With dmap; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h; |
3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Stage #1: 3-iodo-4-toluic acid With thionyl chloride for 1h; Heating / reflux; Stage #2: 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline With N-ethyl-N,N-diisopropylamine; dmap In tetrahydrofuran; benzene at 20℃; for 2h; |
[3-bromo-5-(trifluoromethyl)phenyl]amine
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1-(5,6,7,8-tetrahydroquinolin-8-yl)ethan-1-one; copper(l) iodide; caesium carbonate / N,N-dimethyl-formamide / 18 h / 110 °C / Inert atmosphere; Sealed tube 2: triethylamine / tetrahydrofuran / 1 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: 8-quinolinol; potassium carbonate; copper(l) iodide / dimethyl sulfoxide / 16 h / 40 - 120 °C / Inert atmosphere; Sealed tube 2.1: thionyl chloride / 1 h / Reflux 2.2: 2 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate; copper(l) iodide; 8-quinolinol; ammonia / dimethyl sulfoxide; water / 16 h / 50 - 120 °C / Sealed tube; Inert atmosphere 2: N-ethyl-N,N-diisopropylamine; dmap / tetrahydrofuran; water; thionyl chloride View Scheme | |
Multi-step reaction with 2 steps 1.1: copper(l) iodide; 8-quinolinol / dimethyl sulfoxide / 24 h / 120 °C / Inert atmosphere 2.1: thionyl chloride / 6 h 2.2: 5 h / 60 °C View Scheme |
3-iodo-4-toluic acid
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide; thionyl chloride / 2 h / Reflux 2: triethylamine / tetrahydrofuran / 1 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: thionyl chloride; N,N-dimethyl-formamide / 2 h / Reflux 2: triethylamine / tetrahydrofuran / 1 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: thionyl chloride / N,N-dimethyl-formamide / 2 h / Reflux 2: triethylamine / tetrahydrofuran / 1 h / 0 - 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: thionyl chloride 2: tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
trimethylsilylacetylene
3-ethynyl-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Stage #1: 3-iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide; trimethylsilylacetylene With copper(l) iodide; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine In acetonitrile at 80℃; for 2h; Sonogashira Cross-Coupling; Sealed tube; Inert atmosphere; Stage #2: With potassium carbonate In methanol at 20℃; for 3h; | 90% |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
4-pyridin-3-ylpyrimidin-2-ylamine
nilotinib
Conditions | Yield |
---|---|
With caesium carbonate; tris(dibenzylideneacetone)dipalladium (0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane; tert-butyl alcohol at 100℃; for 7h; | 89% |
With tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,4-dioxane; tert-butyl alcohol at 100℃; for 7h; | 89% |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; palladium dichloride In N,N-dimethyl-formamide at 100℃; for 3h; | 58% |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-acetylenylimidazo[1,2-a]pyridine
Conditions | Yield |
---|---|
With copper(l) iodide; N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 20℃; for 28.25h; Sonogashira coupling; |
9-vinyl-9H-purine
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
AP24348
Conditions | Yield |
---|---|
With palladium diacetate; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 110℃; for 15h; Heck reaction; Inert atmosphere; |
N-cyclopropyl-9-vinyl-9H-purin-6-amine
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
With palladium diacetate; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 110℃; for 15h; Heck reaction; Inert atmosphere; |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-(cyclopropylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 2 h / 80 °C / Inert atmosphere 2: potassium carbonate; methanol / 3 h / 20 °C 3: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 12 h / 60 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 2: potassium carbonate / methanol / 3 h / 20 °C 3: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 12 h / 60 °C / Sealed tube; Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 12 h / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-ethynyl-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / acetonitrile / 2 h / 80 °C / Inert atmosphere 2: potassium carbonate; methanol / 3 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 2: potassium carbonate / methanol / 3 h / 20 °C View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
trimethylsilylacetylene
Conditions | Yield |
---|---|
With bis-triphenylphosphine-palladium(II) chloride; triethylamine In acetonitrile at 80℃; for 2h; Inert atmosphere; | |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In acetonitrile at 80℃; for 2h; Sealed tube; Inert atmosphere; |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 28.25h; Sealed tube; Inert atmosphere; |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-aminopyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-(2-(methylamino)pyrimidin-5-yl)ethynyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-(ethylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-(isopropylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-(cyclohexylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
3-(2-(2-(tert-butylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-(2-(phenylamino)pyrimidin-5-yl)ethynyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-(2-(piperidin-1-yl)pyrimidin-5-yl)ethynyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; triethylamine; copper(l) iodide / acetonitrile / 2 h / 80 °C / Sealed tube; Inert atmosphere 1.2: 3 h / 20 °C 2.1: palladium diacetate; tricyclohexylphosphine; N-ethyl-N,N-diisopropylamine; copper(l) iodide / N,N-dimethyl-formamide / 60 °C / Sealed tube; Inert atmosphere View Scheme |
3-iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Conditions | Yield |
---|---|
Stage #1: 3-iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide; 6-ethynyl-1H-1,8-naphthyridin-2-one With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 80℃; for 5h; Inert atmosphere; Stage #2: With hydrogenchloride In isopropyl alcohol |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View