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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Azacytosine Manufacturer/High quality/Best price/In stock

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Test Items Standards Results Appearance White or off-white crystalline powder comply Loss on drying

High quality 931-86-2 5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Amino-s-triazin-2(1H)-one supplier in China

Cas:931-86-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 5-Azacytosine Cas 931-86-2 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to off-white color powder Storage:Cool dry place Package:1kg/

Hot selling 5-Azacytosine Cas 931-86-2 with factory best quality and price

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $180.0 / 197.0

Type:Trading Company

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Azacytosine

Cas:931-86-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: 5-Azacytosine Synonyms: 5-triazin-2(1h)-one,4-amino-3;2-Amino-4-hydroxy-1,3,5-triazine;2-AMINO-4-HYDROXY-S-TRIAZINE;5-AZACYTOSINE;4-AMINO-1,3,5-TRIAZIN-2-ONE;4-AMINO-1,3,5-TRIAZINE-2[1H]-ONE;4-AMINO-S-TRIAZIN-2(1H)-ONE;5-

931-86-2 5-triazin-2(1h)-one,4-amino-3

Cas:931-86-2

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 5-Azacytosine CAS 931-86-2

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Ality Chemical Corporation

5-Azacytosine Basic information Product Name: 5-Azacytosine Synonyms: 5-triazin-2(1h)-one,4-amino-3;2-Amino-4-hydroxy-1,3,5-triazine;2-AMINO-4-HYDROXY-S-TRIAZINE;4-AMINO-1,3,5-TRIAZIN-2-ONE;4-AMINO-1,3,5-TRIAZINE-2[1H]-ONE;4-AMINO-S-TRIAZIN-2(1

Factory Supply 5-Azacytosine

Cas:931-86-2

Min.Order:1 Gram

Negotiable

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

High PurityCAS 931-86-2 with best price

Cas:931-86-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

pharmaceutical intermediates 5-Azacytosine 931-86-2

Cas:931-86-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

5-Azacytosine CAS:931-86-2

Cas:931-86-2

Min.Order:1 Metric Ton

FOB Price: $380.0 / 590.0

Type:Trading Company

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

High quality 5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

5-Azacytosine

Cas:931-86-2

Min.Order:1 Gram

FOB Price: $10.0

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

5-Azacytosine CAS:931-86-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

5-Azacytosine CAS:931-86-2

Cas:931-86-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

Pharmaceutical Intermediate 5-Azacytosine

Cas:931-86-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:931-86-2

Cas:931-86-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Lonwin Chemical Group Limited

5-Azacytosine CAS: 931-86-2 Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard Shelf life 2 years Storage should be stored in a well-closed c

Factory supply 5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

Negotiable

Type:Other

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Azacytosine

Cas:931-86-2

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:By Sea/Air/Courier Port:Qingdao

5-Azacytosine 931-86-2

Cas:931-86-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 931-86-2 5-Azacytosine

Cas:931-86-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-azacytosine

Cas:931-86-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Name 5-Azacytosine Synonyms 2-Amino-4-hydroxy-1,3,5-triazine; 4-Amino-1,3,5-triazin-2-one Molecular Structure

5-Azacytosine 931-86-2

Cas:931-86-2

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou Maytime Bio-Tech Co.,Ltd.

We are top supplier for decitabine intermediates Application:decitabine intermediate Port:shanghai seaport

5-Azacytosine

Cas:931-86-2

Min.Order:0 Metric Ton

Negotiable

Type:Other

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NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

5-Azacytosine

Cas:931-86-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

5-AZACYTOSINE

Cas:931-86-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

guanylurea formate
10043-39-7

guanylurea formate

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
With sodium methylate In methanol at 40 - 50℃; for 4h; Large scale;90%
Stage #1: guanylurea formate With sodium methylate In methanol at 25 - 35℃; for 0.0833333h;
Stage #2: N,N-dimethyl-formamide dimethyl acetal In methanol at 28 - 50℃;
formic acid
64-18-6

formic acid

N-Cyanoguanidine
127099-85-8, 780722-26-1

N-Cyanoguanidine

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
Stage #1: formic acid; N-Cyanoguanidine With toluene-4-sulfonic acid at 110℃; Autoclave; Large scale;
Stage #2: With hydrogenchloride In water for 0.5h; Temperature; Reagent/catalyst; Reflux; Large scale;
85%
propyl methanoate
110-74-7

propyl methanoate

N-cyanoacetamidine
56563-07-6

N-cyanoacetamidine

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
at 115℃; for 2h;80%
N-cyanoacetamidine
56563-07-6

N-cyanoacetamidine

formic acid ethyl ester
109-94-4

formic acid ethyl ester

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
at 115℃; for 2h;75%
Methyl formate
107-31-3

Methyl formate

N-cyanoacetamidine
56563-07-6

N-cyanoacetamidine

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
at 115℃; for 2h; Temperature;73%
4-amino-2-chloro-1,3,5-triazine
7709-13-9

4-amino-2-chloro-1,3,5-triazine

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
In hydrogenchloride; methanol for 0.5h; Heating;
Conditions
ConditionsYield
With water at 20℃; Acidic aqueous solution;
carbamimidoylurea
141-83-3

carbamimidoylurea

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

5-azacytosine
931-86-2

5-azacytosine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 155℃; for 1.5h;
5-azacytosine
931-86-2

5-azacytosine

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

2-(trimethylsilylamino)-4-(trimethylsilyloxy)-s-triazine
52523-35-0

2-(trimethylsilylamino)-4-(trimethylsilyloxy)-s-triazine

Conditions
ConditionsYield
With ammonium sulfate for 8h; Product distribution / selectivity; Reflux;98%
at 145 - 150℃; for 20h; Concentration;96%
With ammonium sulfate at 120 - 150℃;95.7%
5-azacytosine
931-86-2

5-azacytosine

(S)-tritylglycidol
129940-50-7

(S)-tritylglycidol

1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]-5-azacytosine
933460-54-9

1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]-5-azacytosine

Conditions
ConditionsYield
With sodium hydroxide In dimethyl sulfoxide at 120℃; for 10h;83%
With sodium hydroxide In dimethyl sulfoxide at 120℃; for 10h;83%
Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile at 60 - 85℃; for 2h;
Stage #2: 1,2,3,5-tetra-O-acetyl-α-D-arabinofuranose With trifluorormethanesulfonic acid In acetonitrile at 85℃; for 1h;
75%
1,1,1-trifluoro-2,3-epoxypropane
359-41-1

1,1,1-trifluoro-2,3-epoxypropane

5-azacytosine
931-86-2

5-azacytosine

4-amino-1-(3,3,3-trifluoro-2-hydroxypropyl)-1,3,5-triazin-2(1H)-one

4-amino-1-(3,3,3-trifluoro-2-hydroxypropyl)-1,3,5-triazin-2(1H)-one

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide at 105 - 120℃; for 18h;73%
Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane for 18h; Heating;
Stage #2: 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane at 20℃; for 5h;
70%
5-azacytosine
931-86-2

5-azacytosine

(R)-2-[(diisopropoxyphosphoryl)methoxy]-3-hydroxypropyl p-toluenesulfonate
1160512-81-1

(R)-2-[(diisopropoxyphosphoryl)methoxy]-3-hydroxypropyl p-toluenesulfonate

A

1-[(2S)-2-(diisopropoxyphosphoryl)methoxy-3-hydroxypropyl]-5-azacytosine

1-[(2S)-2-(diisopropoxyphosphoryl)methoxy-3-hydroxypropyl]-5-azacytosine

B

diisopropyl {[(1R)-2-[(4-amino-1,3,5-triazin-2-yl)oxy]-1-(hydroxymethyl)ethoxy]methyl}-phosphonate
1207842-50-9

diisopropyl {[(1R)-2-[(4-amino-1,3,5-triazin-2-yl)oxy]-1-(hydroxymethyl)ethoxy]methyl}-phosphonate

C

3-[(2S)-2-(diisopropoxyphosphoryl)methoxy-3-hydroxypropyl]-5-azacytosine
1207842-49-6

3-[(2S)-2-(diisopropoxyphosphoryl)methoxy-3-hydroxypropyl]-5-azacytosine

Conditions
ConditionsYield
Stage #1: 5-azacytosine With sodium methylate In methanol for 14h; Reflux;
Stage #2: (R)-2-[(diisopropoxyphosphoryl)methoxy]-3-hydroxypropyl p-toluenesulfonate With caesium carbonate In N,N-dimethyl-formamide at 120℃; for 2h; regioselective reaction;
A 62%
B 8%
C 14%
1,2,3,5-tetra-O-acetyl-3-C-ethynyl-D-ribo-pentofuranose
848644-37-1

1,2,3,5-tetra-O-acetyl-3-C-ethynyl-D-ribo-pentofuranose

5-azacytosine
931-86-2

5-azacytosine

1-[2,3,5-tri-O-acetyl-3-C-ethynyl-β-D-ribo-pentofuranosyl]-5-azacytosine
848644-46-2

1-[2,3,5-tri-O-acetyl-3-C-ethynyl-β-D-ribo-pentofuranosyl]-5-azacytosine

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate In acetonitrile at 50℃;50%
5-azacytosine
931-86-2

5-azacytosine

4-methyl-1-phenyl-1H-pyrrol-2(3H)-one

4-methyl-1-phenyl-1H-pyrrol-2(3H)-one

5-methyl-4-[(5-methyl-3-oxo-2-phenyl-2,4-dihydro-3H-pyrazol-4-yl)methylene]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
61466-03-3

5-methyl-4-[(5-methyl-3-oxo-2-phenyl-2,4-dihydro-3H-pyrazol-4-yl)methylene]-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

Conditions
ConditionsYield
In butan-1-ol for 4h; Condensation; Heating;45%
5-azacytosine
931-86-2

5-azacytosine

1-O-acetyl-2-deoxy-3,5-di-O-benzyl-4-thio-D-erythro-pentafuranose
134700-26-8

1-O-acetyl-2-deoxy-3,5-di-O-benzyl-4-thio-D-erythro-pentafuranose

C22H24N4O3S
1161853-96-8

C22H24N4O3S

Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile at 80℃; Reflux;
Stage #2: 1-O-acetyl-2-deoxy-3,5-di-O-benzyl-4-thio-D-erythro-pentafuranose With trifluorormethanesulfonic acid In acetonitrile at 80℃;
44%
5-azacytosine
931-86-2

5-azacytosine

(6aR,9aS)-2,2,4,4-tetraisopropyl-8-((4-(octyloxy)benzyl)thio)tetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocine

(6aR,9aS)-2,2,4,4-tetraisopropyl-8-((4-(octyloxy)benzyl)thio)tetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocine

4-amino-1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-1,3,5-triazin-2(1H)-one

4-amino-1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-1,3,5-triazin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane for 21h; Inert atmosphere; Reflux;
Stage #2: (6aR,9aS)-2,2,4,4-tetraisopropyl-8-((4-(octyloxy)benzyl)thio)tetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocine With N-Bromosuccinimide In dichloromethane at 0℃; for 2h; Inert atmosphere;
41.7%
5-azacytosine
931-86-2

5-azacytosine

2,3-O,O-dibenzyl-4-(5,6-epoxy)-L-ascorbic acid
318239-79-1

2,3-O,O-dibenzyl-4-(5,6-epoxy)-L-ascorbic acid

4-amino-1-[2-(3,4-bis-benzyloxy-5-oxo-2,5-dihydro-furan-2-yl)-2-hydroxy-ethyl]-1H-[1,3,5]triazin-2-one
1313583-60-6

4-amino-1-[2-(3,4-bis-benzyloxy-5-oxo-2,5-dihydro-furan-2-yl)-2-hydroxy-ethyl]-1H-[1,3,5]triazin-2-one

Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane for 3h; Inert atmosphere; Reflux;
Stage #2: 2,3-O,O-dibenzyl-4-(5,6-epoxy)-L-ascorbic acid With trimethylsilyl trifluoromethanesulfonate In acetonitrile at 55 - 70℃; for 12h; Inert atmosphere;
27.2%
5-azacytosine
931-86-2

5-azacytosine

3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine
98495-56-8

3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine

A

α-5',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-deoxy-5-azacytidine
1163302-11-1

α-5',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-deoxy-5-azacytidine

B

β-5',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-deoxy-5-azacytidine
117399-71-0

β-5',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-deoxy-5-azacytidine

Conditions
ConditionsYield
Stage #1: 5-azacytosine; 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-deoxyuridine With N,O-Bis(trimethylsilyl)trifluoroacetamide In dichloromethane for 3h; Reflux; Inert atmosphere;
Stage #2: With trimethylsilyl trifluoromethanesulfonate In dichloromethane for 6h; Reflux; Inert atmosphere;
A n/a
B 25%
5-azacytosine
931-86-2

5-azacytosine

1-O-acetyl-2-deoxy-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-erythro-pentofuranose
457653-05-3

1-O-acetyl-2-deoxy-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-D-erythro-pentofuranose

4-amino-1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-1,3,5-triazin-2(1H)-one

4-amino-1-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-thieno[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-1,3,5-triazin-2(1H)-one

Conditions
ConditionsYield
With chloro-trimethyl-silane; trimethylsilyl trifluoromethanesulfonate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile25%
5-azacytosine
931-86-2

5-azacytosine

2-deoxy–α-D-ribose 1-phosphate
17039-17-7

2-deoxy–α-D-ribose 1-phosphate

5-aza-2'-deoxycytidine
2353-33-5, 22432-95-7

5-aza-2'-deoxycytidine

Conditions
ConditionsYield
With Escherichia coli purine nucleoside phosphorylase In aq. buffer at 20℃; for 0.5h; pH=7; Enzymatic reaction;15%
5-azacytosine
931-86-2

5-azacytosine

5',6'-di-O-acetyl-2',3'-di-O-benzyl-L-ascorbic acid
231619-90-2

5',6'-di-O-acetyl-2',3'-di-O-benzyl-L-ascorbic acid

(Z)-4-amino-1-(2-(3,4-bis(benzyloxy)-5-oxofuran-2(5H)-ylidene)ethyl)-1,3,5-triazin-2(1H)-one
1313583-54-8

(Z)-4-amino-1-(2-(3,4-bis(benzyloxy)-5-oxofuran-2(5H)-ylidene)ethyl)-1,3,5-triazin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 5-azacytosine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane Inert atmosphere; Reflux;
Stage #2: 5',6'-di-O-acetyl-2',3'-di-O-benzyl-L-ascorbic acid With trimethylsilyl trifluoromethanesulfonate In acetonitrile at 55 - 70℃; for 16h; Inert atmosphere;
3.06%
5-azacytosine
931-86-2

5-azacytosine

2-(acetoxymethoxy)-1,3-propanediyl dibenzoate
110874-22-1

2-(acetoxymethoxy)-1,3-propanediyl dibenzoate

4-Amino-1-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1H-[1,3,5]triazin-2-one
82410-28-4

4-Amino-1-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1H-[1,3,5]triazin-2-one

Conditions
ConditionsYield
Yield given. Multistep reaction;
5-azacytosine
931-86-2

5-azacytosine

1-O-acetyl-2,3-di-O-benzoyl-4-thio-DL-erythrofuranoside

1-O-acetyl-2,3-di-O-benzoyl-4-thio-DL-erythrofuranoside

1-(2,3-di-O-benzoyl-4-thio-β-DL-erythrofuranosyl)-5-azacytosine

1-(2,3-di-O-benzoyl-4-thio-β-DL-erythrofuranosyl)-5-azacytosine

Conditions
ConditionsYield
With ammonium sulfate; tin(IV) chloride; 1,1,1,3,3,3-hexamethyl-disilazane 1.) reflux, 3 h, 2.) CH2Cl2, r.t., 10 h; Yield given. Multistep reaction;
5-azacytosine
931-86-2

5-azacytosine

1-O-acetyl-4-(carboethoxy)-2,3-dideoxy-L-ribofuranose
208173-53-9

1-O-acetyl-4-(carboethoxy)-2,3-dideoxy-L-ribofuranose

A

(2R,5S)-5-(4-Amino-2-oxo-2H-[1,3,5]triazin-1-yl)-tetrahydro-furan-2-carboxylic acid ethyl ester

(2R,5S)-5-(4-Amino-2-oxo-2H-[1,3,5]triazin-1-yl)-tetrahydro-furan-2-carboxylic acid ethyl ester

B

(2R,5R)-5-(4-Amino-2-oxo-2H-[1,3,5]triazin-1-yl)-tetrahydro-furan-2-carboxylic acid ethyl ester

(2R,5R)-5-(4-Amino-2-oxo-2H-[1,3,5]triazin-1-yl)-tetrahydro-furan-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With 2,6-dimethylpyridine; trimethylsilyl iodide; t-butyldimethylsiyl triflate 1.) CH2Cl2; 2.) r.t.; Yield given. Multistep reaction. Yields of byproduct given;
5-azacytosine
931-86-2

5-azacytosine

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

acetic anhydride
108-24-7

acetic anhydride

N-(4-Trimethylsilanyloxy-[1,3,5]triazin-2-yl)-acetamide

N-(4-Trimethylsilanyloxy-[1,3,5]triazin-2-yl)-acetamide

Conditions
ConditionsYield
With triethylamine
5-azacytosine
931-86-2

5-azacytosine

1-O-acetyl-2-deoxy-4-thio-3,5-di-O-p-toluoyl-4-thio-D-erythro-pentofuranose
169736-17-8

1-O-acetyl-2-deoxy-4-thio-3,5-di-O-p-toluoyl-4-thio-D-erythro-pentofuranose

A

1-(2-deoxy-3,5-di-O-p-toluoyl-4-thio-β-D-erythropentofuranosyl)-5-azacytosine
676487-18-6

1-(2-deoxy-3,5-di-O-p-toluoyl-4-thio-β-D-erythropentofuranosyl)-5-azacytosine

B

1-(2-deoxy-3,5-di-O-p-toluoyl-4-thio-α-D-erythropentofuranosyl)-5-azacytosine
676487-25-5

1-(2-deoxy-3,5-di-O-p-toluoyl-4-thio-α-D-erythropentofuranosyl)-5-azacytosine

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate Substitution;
Stage #1: 5-azacytosine; 1-O-acetyl-2-deoxy-4-thio-3,5-di-O-p-toluoyl-4-thio-D-erythro-pentofuranose With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile at 20℃; for 0.5h;
Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile at -78℃; for 2.5h;
A 100 mg
B 200 mg
5-azacytosine
931-86-2

5-azacytosine

2-deoxy-1,3,5-tri-O-acetyl-4-thio-L-threo-pentofuranose

2-deoxy-1,3,5-tri-O-acetyl-4-thio-L-threo-pentofuranose

A

1-(2-deoxy-3,5-di-O-acetyl-4-thio-α-L-threopentofuranosyl)-5-azacytosine
676487-27-7

1-(2-deoxy-3,5-di-O-acetyl-4-thio-α-L-threopentofuranosyl)-5-azacytosine

B

1-(2-deoxy-3,5-di-O-acetyl-4-thio-β-L-threopentofuranosyl)-5-azacytosine
676487-22-2

1-(2-deoxy-3,5-di-O-acetyl-4-thio-β-L-threopentofuranosyl)-5-azacytosine

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate Substitution;
Stage #1: 5-azacytosine; 2-deoxy-1,3,5-tri-O-acetyl-4-thio-L-threo-pentofuranose With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile at 20℃; for 0.5h;
Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile at -78℃; for 2h;
A 75 mg
B 160 mg
5-azacytosine
931-86-2

5-azacytosine

(2R)-2-benzyloxymethyl-4-acetoxy-1,3-dioxolane
307002-00-2

(2R)-2-benzyloxymethyl-4-acetoxy-1,3-dioxolane

A

4-Amino-1-((2R,4S)-2-benzyloxymethyl-[1,3]dioxolan-4-yl)-1H-[1,3,5]triazin-2-one

4-Amino-1-((2R,4S)-2-benzyloxymethyl-[1,3]dioxolan-4-yl)-1H-[1,3,5]triazin-2-one

B

4-Amino-1-((2R,4R)-2-benzyloxymethyl-[1,3]dioxolan-4-yl)-1H-[1,3,5]triazin-2-one

4-Amino-1-((2R,4R)-2-benzyloxymethyl-[1,3]dioxolan-4-yl)-1H-[1,3,5]triazin-2-one

Conditions
ConditionsYield
Stage #1: 5-azacytosine With 1,1,1,3,3,3-hexamethyl-disilazane for 4h; silylation; Heating;
Stage #2: (2R)-2-benzyloxymethyl-4-acetoxy-1,3-dioxolane With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane for 18h; Condensation;

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