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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(Diphenyl(trimethylsilyloxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- 943757-71-9

Cas:943757-71-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 943757-71-9 with competitive price

Cas:943757-71-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- CAS:943757-71-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediate

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- CAS:943757-71-9

Cas:943757-71-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyrrolidine,2-[diphenyl[(trimethylsilyl)oxy]methyl]-,(2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(R) -2- (diphenyl(trimethylsilyloxy)met hyl)pyrrolidine

Cas:943757-71-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(R)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine CAS NO.943757-71-9

Cas:943757-71-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- Cas no.943757-71-9 98%

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzhou Port

Pyrrolidine,2-[diphenyl[(trimethylsilyl)oxy]methyl]-,(2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(Diphenyl(trimethylsilyloxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec (R)-Diphenylprolinol Trimethyl Silyl Ether 1g

Cas:943757-71-9

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin

Pyrrolidine,2-[diphenyl[(trimethylsilyl)oxy]methyl]-,(2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

943757-71-9

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SAGECHEM LIMITED

943757-71-9 Application:intermediate

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

R-Diphenylprolinol triMethyl silyl ether

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

Pyrrolidine,2-[diphenyl[(trimethylsilyl)oxy]methyl]-,(2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Scochem Technology Co., Ltd.

High quality suppliers Application:healing drugs

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NUTROCHEM- MANUFACTURE PLACE

best seller Application:API

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HWRK Chem

in store Package:1g Application:Organic Chemicals

4-Fluoro-1-naphthaldehyde

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

(R)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

(R)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine

Cas:943757-71-9

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2-nitro-4-(trifluoromethyl)benzenesulfonyl chloride
837-95-6

2-nitro-4-(trifluoromethyl)benzenesulfonyl chloride

C27H29F3N2O5SSi

C27H29F3N2O5SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;95%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((4-nitrophenyl)sulfonyl)pyrrolidine

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((4-nitrophenyl)sulfonyl)pyrrolidine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;94%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

4-chlorosulfonyl-3-nitrobenzoic acid methyl ester
162010-78-8

4-chlorosulfonyl-3-nitrobenzoic acid methyl ester

C28H32N2O7SSi

C28H32N2O7SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;93%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2-Nitrobenzenesulfonyl chloride
1694-92-4

2-Nitrobenzenesulfonyl chloride

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((2-nitrophenyl)sulfonyl)pyrrolidine

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((2-nitrophenyl)sulfonyl)pyrrolidine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;92%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

3-nitrobenzenesulphonyl chloride
121-51-7

3-nitrobenzenesulphonyl chloride

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((3-nitrophenyl)sulfonyl)pyrrolidine

(R)-2-(diphenyl((trimethylsilyl)oxy)methyl)-1-((3-nitrophenyl)sulfonyl)pyrrolidine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;91%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

4-methoxy-2-nitrobenzenesulfonyl chloride
18092-54-1

4-methoxy-2-nitrobenzenesulfonyl chloride

C27H32N2O6SSi

C27H32N2O6SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;90%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

4-chloro-2-nitrobenzenesulfonyl chloride
4533-96-4

4-chloro-2-nitrobenzenesulfonyl chloride

C26H29ClN2O5SSi

C26H29ClN2O5SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;88%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-4-methyl-2-(2-nitrovinyl)phenol
264224-82-0

(E)-4-methyl-2-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-2,6-dimethyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-98-4

(-)-(E)-ethyl 3-((2S,3R,4R)-2,6-dimethyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-4-methyl-2-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
87%
4-fluoro-2-nitrobenzene-1-sulfonyl chloride
568586-10-7

4-fluoro-2-nitrobenzene-1-sulfonyl chloride

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

C26H29FN2O5SSi

C26H29FN2O5SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;85%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

trans-4-bromo-2-(2-nitrovinyl)phenol
61131-72-4

trans-4-bromo-2-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-6-bromo-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-96-2

(-)-(E)-ethyl 3-((2S,3R,4R)-6-bromo-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; trans-4-bromo-2-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
83%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

4-fluoro-2-((E)-2-nitrovinyl)phenol
1308249-79-7

4-fluoro-2-((E)-2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-6-fluoro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-94-0

(-)-(E)-ethyl 3-((2S,3R,4R)-6-fluoro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 4-fluoro-2-((E)-2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
82%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-4-chloro-2-(2-nitroethenyl)phenol
61131-68-8

(E)-4-chloro-2-(2-nitroethenyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-6-chloro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-95-1

(-)-(E)-ethyl 3-((2S,3R,4R)-6-chloro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-4-chloro-2-(2-nitroethenyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
82%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2,4-chloro-2-((E)-2-nitrovinyl)phenol
1310493-82-3

2,4-chloro-2-((E)-2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-6,8-dichloro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-97-3

(-)-(E)-ethyl 3-((2S,3R,4R)-6,8-dichloro-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 2,4-chloro-2-((E)-2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
82%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-4-methoxy-2-(2-nitrovinyl)phenol
35467-98-2

(E)-4-methoxy-2-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-6-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-99-5

(-)-(E)-ethyl 3-((2S,3R,4R)-6-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-4-methoxy-2-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
82%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

2-((1E)-2-nitrovinyl)-4-nitrophenol

2-((1E)-2-nitrovinyl)-4-nitrophenol

(-)-(E)-ethyl 3-((2S,3R,4R)-8-hydroxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631166-02-3

(-)-(E)-ethyl 3-((2S,3R,4R)-8-hydroxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; acetaldehyde; 2-((1E)-2-nitrovinyl)-4-nitrophenol In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
80%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2-[(E)-2-nitrovinyl]phenol
3156-43-2

2-[(E)-2-nitrovinyl]phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631165-93-9

(-)-(E)-ethyl 3-((2S,3R,4R)-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 2-[(E)-2-nitrovinyl]phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h; Reagent/catalyst; Concentration; Temperature; Solvent;
80%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-5-methoxy-2-(2-nitrovinyl)phenol
96853-34-8

(E)-5-methoxy-2-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-7-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631166-00-1

(-)-(E)-ethyl 3-((2S,3R,4R)-7-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-5-methoxy-2-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
80%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2-[(E)-2-nitrovinyl]phenol
3156-43-2

2-[(E)-2-nitrovinyl]phenol

acetaldehyde
75-07-0

acetaldehyde

(-)-(2S,3R,4R)-2-methyl-4-(nitromethyl)chroman-3-carbaldehyde
1631165-92-8

(-)-(2S,3R,4R)-2-methyl-4-(nitromethyl)chroman-3-carbaldehyde

Conditions
ConditionsYield
In chloroform at -40 - -5℃; for 3.25h;80%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-2-methoxy-6-(2-nitrovinyl)phenol
1986-06-7, 141849-32-3

(E)-2-methoxy-6-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-8-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631166-01-2

(-)-(E)-ethyl 3-((2S,3R,4R)-8-methoxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-2-methoxy-6-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
75%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

(E)-3-(2-nitrovinyl)benzene-1,2-diol
1308250-94-3

(E)-3-(2-nitrovinyl)benzene-1,2-diol

acetaldehyde
75-07-0

acetaldehyde

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

(-)-(E)-ethyl 3-((2S,3R,4R)-8-hydroxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate
1631166-02-3

(-)-(E)-ethyl 3-((2S,3R,4R)-8-hydroxy-2-methyl-4-(nitromethyl)chroman-3-yl)acrylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-3-(2-nitrovinyl)benzene-1,2-diol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl (triphenylphosphoranylidene)acetate In chloroform at 20℃; for 2h;
75%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

2-[(E)-2-nitrovinyl]phenol
3156-43-2

2-[(E)-2-nitrovinyl]phenol

acetaldehyde
75-07-0

acetaldehyde

(-)-((2S,3S,4R)-2-methyl-4-(nitromethyl)chroman-3-yl)methanol
1631165-85-9

(-)-((2S,3S,4R)-2-methyl-4-(nitromethyl)chroman-3-yl)methanol

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 2-[(E)-2-nitrovinyl]phenol; acetaldehyde In chloroform at -40 - -5℃; for 3.25h;
Stage #2: With methanol; sodium tetrahydroborate In chloroform at 0℃; for 1h;
75%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

ethyl 2-diethoxyphosphinoylacrylate
20345-61-3

ethyl 2-diethoxyphosphinoylacrylate

2-[(E)-2-nitrovinyl]phenol
3156-43-2

2-[(E)-2-nitrovinyl]phenol

acetaldehyde
75-07-0

acetaldehyde

(-)-(6S,6aR,10S,10aR)-ethyl 6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate
1631166-04-5

(-)-(6S,6aR,10S,10aR)-ethyl 6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 2-[(E)-2-nitrovinyl]phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl 2-diethoxyphosphinoylacrylate With caesium carbonate In dichloromethane at 0℃; for 6h; Inert atmosphere;
Stage #3: With ethanol In dichloromethane at 0 - 20℃; for 2h;
75%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

isovaleraldehyde
590-86-3

isovaleraldehyde

C25H35NOSi

C25H35NOSi

Conditions
ConditionsYield
In dimethylsulfoxide-d675%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

ethyl 2-diethoxyphosphinoylacrylate
20345-61-3

ethyl 2-diethoxyphosphinoylacrylate

(E)-3-(2-nitrovinyl)benzene-1,2-diol
1308250-94-3

(E)-3-(2-nitrovinyl)benzene-1,2-diol

acetaldehyde
75-07-0

acetaldehyde

(-)-(6S,6aR,10S,10aR)-ethyl 4-hydroxy-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate
1631166-07-8

(-)-(6S,6aR,10S,10aR)-ethyl 4-hydroxy-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; (E)-3-(2-nitrovinyl)benzene-1,2-diol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl 2-diethoxyphosphinoylacrylate With caesium carbonate In dichloromethane at 0℃; for 6h; Inert atmosphere;
Stage #3: With ethanol In dichloromethane at 0 - 20℃; for 2h;
72%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

ethyl 2-diethoxyphosphinoylacrylate
20345-61-3

ethyl 2-diethoxyphosphinoylacrylate

2,4-chloro-2-((E)-2-nitrovinyl)phenol
1310493-82-3

2,4-chloro-2-((E)-2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

(-)-(6S,6aR,10S,10aR)-ethyl 2,4-dichloro-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate
1631166-06-7

(-)-(6S,6aR,10S,10aR)-ethyl 2,4-dichloro-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; 2,4-chloro-2-((E)-2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl 2-diethoxyphosphinoylacrylate With caesium carbonate In dichloromethane at 0℃; for 6h; Inert atmosphere;
Stage #3: With ethanol In dichloromethane at 0 - 20℃; for 2h;
70%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

ethyl 2-diethoxyphosphinoylacrylate
20345-61-3

ethyl 2-diethoxyphosphinoylacrylate

trans-4-bromo-2-(2-nitrovinyl)phenol
61131-72-4

trans-4-bromo-2-(2-nitrovinyl)phenol

acetaldehyde
75-07-0

acetaldehyde

(-)-(6S,6aR,10S,10aR)-ethyl 2-bromo-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate
1631166-05-6

(-)-(6S,6aR,10S,10aR)-ethyl 2-bromo-6-methyl-10-nitro-6a,9,10,10a-tetrahydro-6H-benzo[c]chromene-8-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; trans-4-bromo-2-(2-nitrovinyl)phenol; acetaldehyde In chloroform at -40 - -5℃; Wittig-Horner Reaction;
Stage #2: ethyl 2-diethoxyphosphinoylacrylate With caesium carbonate In dichloromethane at 0℃; for 6h; Inert atmosphere;
Stage #3: With ethanol In dichloromethane at 0 - 20℃; for 2h;
67%
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

1-nitroethanol
39221-06-2

1-nitroethanol

4-methoxy-trans-cinnamaldehyde
24680-50-0, 71277-11-7, 1963-36-6

4-methoxy-trans-cinnamaldehyde

(4R,5R)-4-(2-methoxyphenyl)-5-nitrotetrahydro-2H-pyran-2-ol

(4R,5R)-4-(2-methoxyphenyl)-5-nitrotetrahydro-2H-pyran-2-ol

Conditions
ConditionsYield
With benzoic acid In methanol at 40℃; for 10h; Inert atmosphere;51%
nitrostyrene
5153-67-3

nitrostyrene

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

acetaldehyde
75-07-0

acetaldehyde

A

(3R)-4-nitro-3-phenylbutanal
934269-53-1

(3R)-4-nitro-3-phenylbutanal

B

C14H15NO3

C14H15NO3

Conditions
ConditionsYield
In chloroform at -40 - -5℃; for 96h;A 25%
B 25%
nitrostyrene
5153-67-3

nitrostyrene

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

5-formy-1,3,6-trimethyluracil
23941-84-6

5-formy-1,3,6-trimethyluracil

(5R,6R,7R)-5-((R)-2-(diphenyl((trimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-1,3-dimethyl-6-nitro-7-phenyl-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione

(5R,6R,7R)-5-((R)-2-(diphenyl((trimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-1,3-dimethyl-6-nitro-7-phenyl-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione

Conditions
ConditionsYield
In dichloromethane at 25℃; for 24h; Inert atmosphere;18%
nitrostyrene
5153-67-3

nitrostyrene

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine
943757-71-9

(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine

C8H7NO2*C20H27NOSi

C8H7NO2*C20H27NOSi

Conditions
ConditionsYield
In methanol for 0.166667h;

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