100276-64-0 Usage
Description
2,3,4,5-Tetrafluoro-α-[(2-formyl-2-methylhydrazinyl)methylene]-β-oxobenzenepropanoic Acid Ethyl Ester is a complex organic compound characterized by its tetrafluoro substitution on the benzene ring and a unique methylene bridge connecting a formyl group to a methylhydrazinyl moiety. This molecule serves as a crucial intermediate in the synthesis of various pharmaceutical compounds due to its structural complexity and reactivity.
Uses
Used in Pharmaceutical Industry:
2,3,4,5-Tetrafluoro-α-[(2-formyl-2-methylhydrazinyl)methylene]-β-oxobenzenepropanoic Acid Ethyl Ester is used as an intermediate in the synthesis of Marbofloxacin (M197000), a fluorinated quinolone antibacterial agent. Its role in the synthesis process is essential for creating the final drug product, which is effective against a wide range of bacterial infections.
Marbofloxacin, as a fluorinated quinolone, is known for its broad-spectrum antibacterial activity, making it a valuable compound in the treatment of various bacterial infections in both humans and animals. The ester's contribution to the development of such an important antibiotic highlights its significance in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 100276-64-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,2,7 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 100276-64:
(8*1)+(7*0)+(6*0)+(5*2)+(4*7)+(3*6)+(2*6)+(1*4)=80
80 % 10 = 0
So 100276-64-0 is a valid CAS Registry Number.
100276-64-0Relevant articles and documents
Process for the manufacture of a tricyclic compound
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, (2008/06/13)
A process for preparing a compound of formula (I) or a phamaceutically-acceptable salt thereof, comprising: 1) reacting a compound. of formula (III), in which R is a straight or branched chain alkyl having from one to four carbon atoms, with an alkali metal hydroxide in an aqueous medium at a temperature of about 80° to 120° C. and time of about 20 to 100 hours to form a reaction product; 2) cyclizing the reaction product of step 1) with formic acid and formaldehyde to form a formiate compound; and 3) neutralizing the formiate compound of step 2) with an aqueous base.
